Strain Name:
C57BL/6J-MtgxR9322Btlr/Mmmh
Stock Number:
069134-MU
Citation ID:
RRID:MMRRC_069134-MU
Other Names:
R9322 (G1)
Major Collection:

Strain Information

Fasl
Name: Fas ligand
Synonyms: Fasl, CD95L, CD178, Fas-L, Tnfsf6, APT1LG1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14103
Homologene: 533
Il23a
Name: interleukin 23, alpha subunit p19
Synonyms: p19, IL-23p19, IL-23
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83430
VEGA: 10
Homologene: 12832
Usp7
Name: ubiquitin specific peptidase 7
Synonyms: 2210010O09Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 252870
Homologene: 2592
Slc44a2
Name: solute carrier family 44, member 2
Synonyms: 1110028E10Rik, CTL2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68682
VEGA: 9
Homologene: 10711
Csrnp1
Name: cysteine-serine-rich nuclear protein 1
Synonyms: CSRNP-1, Axud1, taip-3, 4931429D10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215418
VEGA: 9
Homologene: 13196
Mid1
Name: midline 1
Synonyms: 61B3-R, DXHXS1141, Trim18, Fxy
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 17318
HGNC: HGNC:7095
Homologene: 7837
Ccdc9
Name: coiled-coil domain containing 9
Synonyms: 2600011L02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243846
Homologene: 9209
Med4
Name: mediator complex subunit 4
Synonyms: HSPC126, p36 TRAP/SMCC/PC2 subunit, DRIP36, 2410046H15Rik, MED4, TRAP36, Vdrip
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67381
VEGA: 14
Homologene: 8568
Lhx4
Name: LIM homeobox protein 4
Synonyms: A330062J17Rik, Gsh4, Gsh-4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16872
Homologene: 56497
Slc18a3
Name: solute carrier family 18 (vesicular monoamine), member 3
Synonyms: VAChT, VAT
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 20508
Homologene: 11022
Epha6
Name: Eph receptor A6
Synonyms: m-ehk2, Ehk2, Hek12
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13840
Homologene: 56396
Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Synonyms: D3Ertd557e, ESTM42, Hif1b, bHLHe2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11863
HGNC: HGNC:700
Homologene: 1261
Csnk1g2
Name: casein kinase 1, gamma 2
Synonyms: 2810429I12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103236
VEGA: 10
HGNC: HGNC:2455
Homologene: 100845
Nbeal1
Name: neurobeachin like 1
Synonyms: A530050O19Rik, A530083I02Rik, ALS2CR17, 2310076G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269198
Homologene: 16453
Sfrp2
Name: secreted frizzled-related protein 2
Synonyms: Sdf5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20319
Homologene: 56438
Rlbp1
Name: retinaldehyde binding protein 1
Synonyms: CRALBP, 3110056M11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19771
Homologene: 68046
Asic4
Name: acid-sensing ion channel family member 4
Synonyms: Accn4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241118
Homologene: 11166
Skic2
Name: SKI2 subunit of superkiller complex
Synonyms: Ski2w, 4930534J06Rik, Skiv2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 108077
Homologene: 123971
Cat
Name: catalase
Synonyms: Cas-1, Cs-1, Cas1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12359
HGNC: HGNC:1516
Homologene: 55514
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Itpr5, Ip3r2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Ttc16
Name: tetratricopeptide repeat domain 16
Synonyms: 1200002K10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 338348
Homologene: 17011
Psd
Name: pleckstrin and Sec7 domain containing
Synonyms: 1110007H17Rik, Psdl, Efa6a, Efa6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73728
VEGA: 19
HGNC: HGNC:9507
Homologene: 31115
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 637515
Homologene: 19080
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL19, DLP12, 4921531P07Rik, HL-19, DHC3, LOC380889, Dnahc12, Dnahc7l
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Pik3r2
Name: phosphoinositide-3-kinase regulatory subunit 2
Synonyms: p85beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18709
HGNC: HGNC:8980
Homologene: 3687
Vmn2r70
Name: vomeronasal 2, receptor 70
Synonyms: EG620835
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670940
Homologene: 115466
Trim67
Name: tripartite motif-containing 67
Synonyms: D130049O21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330863
Homologene: 45699
St18
Name: suppression of tumorigenicity 18
Synonyms: Nzf3, Myt3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240690
Homologene: 8792
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22313
Homologene: 129751
Ciao3
Name: cytosolic iron-sulfur assembly component 3
Synonyms: 9030612I22Rik, Narfl
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67563
Homologene: 6750
Filip1
Name: filamin A interacting protein 1
Synonyms: 5730485H21Rik, FILIP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70598
Homologene: 6700
Abca5
Name: ATP-binding cassette, sub-family A member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Fmo5
Name: flavin containing monooxygenase 5
Synonyms: 5033418D19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14263
HGNC: HGNC:3773
Homologene: 68185
Grm8
Name: glutamate receptor, metabotropic 8
Synonyms: Gprc1h, mGluR8
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14823
HGNC: HGNC:4600
Homologene: 654
Arhgef33
Name: Rho guanine nucleotide exchange factor 33
Synonyms: Gm941, LOC381112
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381112
VEGA: 17
Homologene: 55190
Mief2
Name: mitochondrial elongation factor 2
Synonyms: LOC237781, Smcr7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237781
Homologene: 27354
Nat3
Name: N-acetyltransferase 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17962
Homologene: 69026
Pdha2
Name: pyruvate dehydrogenase E1 alpha 2
Synonyms: Pdhal
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18598
HGNC: HGNC:8807
Homologene: 137212
Zer1
Name: zyg-11 related, cell cycle regulator
Synonyms: C230075L19Rik, Zyg11bl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227693
Homologene: 4621
Or5p4
Name: olfactory receptor family 5 subfamily P member 4
Synonyms: MOR204-2, GA_x6K02T2PBJ9-10409785-10410723, Olfr481, MOR204-39
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258927
Homologene: 105166
Dsn1
Name: DSN1 homolog, MIS12 kinetochore complex component
Synonyms: 1700022L09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66934
Homologene: 49806
Psme3
Name: proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Synonyms: PA28gamma, Ki, REGgamma, pa28g
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19192
HGNC: HGNC:9570
Homologene: 2111
Ccdc121rt3
Name: coiled-coil domain containing 121, retrogene 3
Synonyms: Gm6583
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 625424
Homologene: 116059
Or11h23
Name: olfactory receptor family 11 subfamily G member 23
Synonyms: Olfr748, MOR106-9P, GA_x6K02T2PMLR-6454789-6455712
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258113
Homologene: 134081
Krt79
Name: keratin 79
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223917
Homologene: 89169
Or5aq7
Name: olfactory receptor family 5 subfamily AQ member 7
Synonyms: GA_x6K02T2N869-1820-882, MOR172-3, Olfr259
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258766
Homologene: 106833
Scn1b
Name: sodium channel, voltage-gated, type I, beta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20266
Homologene: 810
Gm5157
Name: predicted gene 5157
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381937
Homologene: 128656
Dchs2
Name: dachsous cadherin related 2
Synonyms: LOC229459
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100534287
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 6,795,523 bp (GRCm38)
  • T to A, chromosome 1 at 60,258,659 bp (GRCm38)
  • A to G, chromosome 1 at 75,469,818 bp (GRCm38)
  • A to G, chromosome 1 at 155,702,607 bp (GRCm38)
  • A to T, chromosome 1 at 161,781,943 bp (GRCm38)
  • A to G, chromosome 1 at 172,280,058 bp (GRCm38)
  • A to T, chromosome 2 at 30,110,911 bp (GRCm38)
  • C to T, chromosome 2 at 32,774,940 bp (GRCm38)
  • T to C, chromosome 2 at 87,108,217 bp (GRCm38)
  • T to C, chromosome 2 at 103,472,988 bp (GRCm38)
  • C to T, chromosome 2 at 157,001,749 bp (GRCm38)
  • T to A, chromosome 3 at 83,281,694 bp (GRCm38)
  • T to C, chromosome 3 at 83,766,699 bp (GRCm38)
  • T to C, chromosome 3 at 95,490,618 bp (GRCm38)
  • A to T, chromosome 3 at 97,638,874 bp (GRCm38)
  • C to A, chromosome 3 at 141,210,789 bp (GRCm38)
  • T to A, chromosome 5 at 112,355,406 bp (GRCm38)
  • T to A, chromosome 6 at 27,363,729 bp (GRCm38)
  • T to C, chromosome 6 at 146,325,089 bp (GRCm38)
  • T to C, chromosome 7 at 16,278,435 bp (GRCm38)
  • T to G, chromosome 7 at 21,185,506 bp (GRCm38)
  • C to A, chromosome 7 at 31,125,092 bp (GRCm38)
  • T to C, chromosome 7 at 79,377,255 bp (GRCm38)
  • T to C, chromosome 7 at 85,559,290 bp (GRCm38)
  • C to T, chromosome 7 at 108,081,520 bp (GRCm38)
  • A to T, chromosome 8 at 67,547,510 bp (GRCm38)
  • A to G, chromosome 8 at 70,774,850 bp (GRCm38)
  • C to A, chromosome 8 at 124,823,228 bp (GRCm38)
  • A to T, chromosome 9 at 21,346,950 bp (GRCm38)
  • A to T, chromosome 9 at 79,819,732 bp (GRCm38)
  • T to C, chromosome 9 at 119,972,787 bp (GRCm38)
  • T to C, chromosome 10 at 80,639,144 bp (GRCm38)
  • T to C, chromosome 10 at 128,297,121 bp (GRCm38)
  • A to T, chromosome 11 at 60,731,018 bp (GRCm38)
  • T to C, chromosome 11 at 71,217,292 bp (GRCm38)
  • A to C, chromosome 11 at 101,320,611 bp (GRCm38)
  • A to T, chromosome 11 at 104,874,373 bp (GRCm38)
  • A to G, chromosome 11 at 110,301,505 bp (GRCm38)
  • A to T, chromosome 14 at 26,770,977 bp (GRCm38)
  • A to G, chromosome 14 at 32,463,325 bp (GRCm38)
  • C to A, chromosome 14 at 50,711,050 bp (GRCm38)
  • T to C, chromosome 14 at 73,510,161 bp (GRCm38)
  • T to A, chromosome 15 at 101,931,810 bp (GRCm38)
  • A to T, chromosome 16 at 8,699,260 bp (GRCm38)
  • A to T, chromosome 16 at 60,424,755 bp (GRCm38)
  • T to C, chromosome 17 at 20,042,825 bp (GRCm38)
  • G to C, chromosome 17 at 25,779,574 bp (GRCm38)
  • T to C, chromosome 17 at 34,847,463 bp (GRCm38)
  • T to A, chromosome 17 at 80,370,389 bp (GRCm38)
  • T to A, chromosome 19 at 46,313,441 bp (GRCm38)
  • C to G, chromosome X at 169,985,007 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9322 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069134-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.