Strain Name:
C57BL/6J-MtgxR9331Btlr/Mmmh
Stock Number:
069143-MU
Citation ID:
RRID:MMRRC_069143-MU
Other Names:
R9331 (G1)
Major Collection:

Strain Information

Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: Nos-1, nNOS, 2310005C01Rik, bNOS, NO
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Npy2r
Name: neuropeptide Y receptor Y2
Synonyms: NPY-Y2 receptor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18167
HGNC: HGNC:7957
Homologene: 701
P2rx7
Name: purinergic receptor P2X, ligand-gated ion channel, 7
Synonyms: P2X7 receptor, P2X7R, P2X(7)
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18439
HGNC: HGNC:8537
Homologene: 1925
Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74753
Homologene: 32316
Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330953
VEGA: 9
Homologene: 3997
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Diaph3
Name: diaphanous related formin 3
Synonyms: mDia2, Diap3, Drf3, p134MDia2, 4930417P13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56419
VEGA: 14
Homologene: 84829
Ccnt1
Name: cyclin T1
Synonyms: CycT1, 2810478G24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12455
HGNC: HGNC:1599
Homologene: 947
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE-1, A330049M09Rik, enaptin165, nesprin-1, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Ei24
Name: etoposide induced 2.4 mRNA
Synonyms: PIG8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13663
Homologene: 3588
Polg
Name: polymerase (DNA directed), gamma
Synonyms: polymerase gamma, mitochondrial DNA polymerase-gamma, mitochondrial DNA polymerase gamma, Pol gamma, Polga
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18975
HGNC: HGNC:9179
Homologene: 2016
Cd72
Name: CD72 antigen
Synonyms: Ly-19, Ly-m19, Ly-32, Lyb-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12517
HGNC: HGNC:1696
Homologene: 1350
Tmub1
Name: transmembrane and ubiquitin-like domain containing 1
Synonyms: Hops, 2010004O20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 64295
Homologene: 11187
Crispld1
Name: cysteine-rich secretory protein LCCL domain containing 1
Synonyms: Cocoacrisp
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 83691
Homologene: 12857
Fgf21
Name: fibroblast growth factor 21
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56636
HGNC: HGNC:3678
Homologene: 10428
Tmco1
Name: transmembrane and coiled-coil domains 1
Synonyms: ESTM39, 4930403O06Rik, 1190006A08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68944
Homologene: 10384
Unkl
Name: unkempt family like zinc finger
Synonyms: 1300004G08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74154
Homologene: 62673
Ap3m1
Name: adaptor-related protein complex 3, mu 1 subunit
Synonyms: C78982, 1200013D09Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 55946
HGNC: HGNC:569
Homologene: 22693
Zfp386
Name: zinc finger protein 386 (Kruppel-like)
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56220
Homologene: 51668
Plekho2
Name: pleckstrin homology domain containing, family O member 2
Synonyms: Plekhq1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102595
VEGA: 9
Homologene: 11870
Hexim1
Name: hexamethylene bis-acetamide inducible 1
Synonyms: HIS1, Clp1, 7330426E13Rik, CLP-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192231
Homologene: 31382
Pde12
Name: phosphodiesterase 12
Synonyms: E430028B21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 211948
Homologene: 14272
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240255
Homologene: 11265
Cacna1a
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Synonyms: nmf352, Cacnl1a4, Ccha1a, smrl, alpha1A, SCA6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12286
HGNC: HGNC:1388
Homologene: 56383
Smarcc2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Synonyms: 5930405J04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68094
VEGA: 10
Homologene: 2312
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: Abc3, ABC-C, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Hyal4
Name: hyaluronoglucosaminidase 4
Synonyms: 4632428M18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77042
HGNC: HGNC:5323
Homologene: 69117
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: D930026N18Rik, (alpha)1 subunit, L-type Cav1.2, Cchl1a1, Cav1.2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Mccc1
Name: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Synonyms: MCCalpha, 1810045E08Rik, MCCA, 2310058B18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72039
HGNC: HGNC:6936
Homologene: 10603
Nprl2
Name: NPR2 like, GATOR1 complex subunit
Synonyms: G21, NPRL2, Tusc4, 2810446G01Rik, NPR2L
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56032
Homologene: 4771
Actrt3
Name: actin related protein T3
Synonyms: Arpm1, 1700119I24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76652
Homologene: 13038
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227334
Homologene: 32400
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Pwwp2b
Name: PWWP domain containing 2B
Synonyms: Pwwp2, D7Ertd517e, D930023J19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101631
Homologene: 19056
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: 2300002I04Rik, MUC5, MUC9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Abca8a
Name: ATP-binding cassette, sub-family A member 8a
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Plcl1
Name: phospholipase C-like 1
Synonyms: C230017K02Rik, PRIP-1, PLC-L
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227120
HGNC: HGNC:9063
Homologene: 38155
Gne
Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Synonyms: 2310066H07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 50798
Homologene: 3996
Hoxd8
Name: homeobox D8
Synonyms: 4921540P06Rik, Hox-5.4, Hox-4.3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15437
HGNC: HGNC:5139
Homologene: 10473
Gdap1l1
Name: ganglioside-induced differentiation-associated protein 1-like 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228858
HGNC: HGNC:4213
Homologene: 11426
Tubb1
Name: tubulin, beta 1 class VI
Synonyms: 2810484G07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545486
Homologene: 69474
Ptar1
Name: protein prenyltransferase alpha subunit repeat containing 1
Synonyms: 4930428J16Rik, 2010013L17Rik, 1700084D09Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72351
VEGA: 19
Homologene: 34254
Xaf1
Name: XIAP associated factor 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327959
Homologene: 49488
Or8c10
Name: olfactory receptor family 8 subfamily C member 10
Synonyms: GA_x6K02T2PVTD-32060891-32061865, MOR170-8, GA_x6K02T2MYUG-19447-18473, MOR170-14, Olfr250, Olfr899
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 404312
VEGA: 9
Homologene: 74151
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Hkdc1
Name: hexokinase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216019
Homologene: 128937
Adam3
Name: ADAM metallopeptidase domain 3
Synonyms: Taz83, ADAM3, Taz83, tMDC, Cyrn1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11497
HGNC: HGNC:209
Homologene: 69052
Klk15
Name: kallikrein related-peptidase 15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 317652
Homologene: 77571
Adamts8
Name: ADAM metallopeptidase with thrombospondin type 1 motif 8
Synonyms: METH-2, METH2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 30806
HGNC: HGNC:224
Homologene: 5108
Zfp456
Name: zinc finger protein 456
Synonyms: Rslcan-13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408065
Homologene: 110878
Prl7a2
Name: prolactin family 7, subfamily a, member 2
Synonyms: Prlpf, PLP-F
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19114
Homologene: 49263
Fdxacb1
Name: ferredoxin-fold anticodon binding domain containing 1
Synonyms: D630004A14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382137
Homologene: 19813
Or8b9
Name: olfactory receptor family 8 subfamily B member 9
Synonyms: Olfr877, GA_x6K02T2PVTD-31540342-31541277, MOR161-5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258412
Homologene: 121556
Vmn2r32
Name: vomeronasal 2, receptor 32
Synonyms: V2r5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22311
Homologene: 113703
Pacc1
Name: proton activated chloride channel 1
Synonyms: Tmem206, 2310028N02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66950
Homologene: 10097
Agpat2
Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
Synonyms: BSCL1, LPAAT-beta, 2510002J07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67512
HGNC: HGNC:325
Homologene: 4678
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: Gm9813, LOC217602, AU024163, 4921506M07Rik, EG639426
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70846
Homologene: 78002
Gm44501
Name: predicted readthrough transcript, 44501
Synonyms: Esp6Esp5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 102577428
VEGA: 17
Homologene: 136357
Ighv5-9-1
Name: immunoglobulin heavy variable 5-9-1
Synonyms: Gm16886
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 641178
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 17,762,230 bp (GRCm38)
  • T to C, chromosome 1 at 26,683,709 bp (GRCm38)
  • T to C, chromosome 1 at 55,696,871 bp (GRCm38)
  • A to G, chromosome 1 at 87,974,106 bp (GRCm38)
  • C to T, chromosome 1 at 167,308,563 bp (GRCm38)
  • T to C, chromosome 1 at 191,345,121 bp (GRCm38)
  • A to G, chromosome 2 at 26,597,306 bp (GRCm38)
  • CGCGGCGGCGGCGGCGGC to CGCGGCGGCGGCGGC, chromosome 2 at 74,705,598 bp (GRCm38)
  • A to T, chromosome 2 at 163,453,744 bp (GRCm38)
  • A to G, chromosome 2 at 174,455,679 bp (GRCm38)
  • T to C, chromosome 3 at 30,597,901 bp (GRCm38)
  • A to G, chromosome 3 at 35,960,089 bp (GRCm38)
  • A to G, chromosome 3 at 82,540,761 bp (GRCm38)
  • T to A, chromosome 4 at 43,454,320 bp (GRCm38)
  • A to G, chromosome 4 at 44,066,845 bp (GRCm38)
  • A to C, chromosome 4 at 46,387,642 bp (GRCm38)
  • T to C, chromosome 5 at 24,445,987 bp (GRCm38)
  • T to C, chromosome 5 at 117,900,524 bp (GRCm38)
  • T to C, chromosome 5 at 122,680,898 bp (GRCm38)
  • A to T, chromosome 6 at 24,765,867 bp (GRCm38)
  • C to T, chromosome 6 at 119,107,948 bp (GRCm38)
  • G to A, chromosome 7 at 7,464,403 bp (GRCm38)
  • C to T, chromosome 7 at 43,938,366 bp (GRCm38)
  • G to T, chromosome 7 at 45,614,190 bp (GRCm38)
  • T to C, chromosome 7 at 79,458,400 bp (GRCm38)
  • G to A, chromosome 7 at 139,255,441 bp (GRCm38)
  • C to A, chromosome 7 at 141,857,738 bp (GRCm38)
  • A to G, chromosome 8 at 24,687,935 bp (GRCm38)
  • C to T, chromosome 8 at 84,415,817 bp (GRCm38)
  • A to T, chromosome 9 at 30,951,474 bp (GRCm38)
  • A to G, chromosome 9 at 36,789,921 bp (GRCm38)
  • G to A, chromosome 9 at 37,855,414 bp (GRCm38)
  • A to G, chromosome 9 at 38,367,707 bp (GRCm38)
  • G to A, chromosome 9 at 50,770,211 bp (GRCm38)
  • T to C, chromosome 9 at 58,860,422 bp (GRCm38)
  • C to A, chromosome 9 at 65,556,584 bp (GRCm38)
  • G to A, chromosome 9 at 107,544,756 bp (GRCm38)
  • C to G, chromosome 10 at 5,123,666 bp (GRCm38)
  • A to T, chromosome 10 at 62,400,335 bp (GRCm38)
  • A to T, chromosome 10 at 128,487,441 bp (GRCm38)
  • T to C, chromosome 11 at 72,306,644 bp (GRCm38)
  • C to T, chromosome 11 at 103,117,148 bp (GRCm38)
  • A to G, chromosome 11 at 110,026,328 bp (GRCm38)
  • C to A, chromosome 12 at 57,673,723 bp (GRCm38)
  • C to T, chromosome 12 at 84,876,191 bp (GRCm38)
  • T to C, chromosome 12 at 113,736,258 bp (GRCm38)
  • C to T, chromosome 12 at 116,047,813 bp (GRCm38)
  • A to G, chromosome 13 at 27,665,079 bp (GRCm38)
  • T to A, chromosome 13 at 67,366,270 bp (GRCm38)
  • A to G, chromosome 14 at 21,045,598 bp (GRCm38)
  • T to C, chromosome 14 at 26,668,673 bp (GRCm38)
  • G to T, chromosome 14 at 87,141,025 bp (GRCm38)
  • T to A, chromosome 15 at 98,543,216 bp (GRCm38)
  • A to G, chromosome 17 at 24,397,350 bp (GRCm38)
  • G to A, chromosome 17 at 25,231,749 bp (GRCm38)
  • G to A, chromosome 17 at 40,578,729 bp (GRCm38)
  • T to A, chromosome 18 at 34,629,509 bp (GRCm38)
  • T to A, chromosome 18 at 44,837,432 bp (GRCm38)
  • T to C, chromosome 19 at 6,398,099 bp (GRCm38)
  • T to A, chromosome 19 at 23,694,343 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9331 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069143-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.