Strain Name:
C57BL/6J-MtgxR9341Btlr/Mmmh
Stock Number:
069152-MU
Citation ID:
RRID:MMRRC_069152-MU
Other Names:
R9341 (G1)
Major Collection:

Strain Information

Strn4
Name: striatin, calmodulin binding protein 4
Synonyms: ZIN, zinedin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 97387
Homologene: 8378
S1pr3
Name: sphingosine-1-phosphate receptor 3
Synonyms: S1P3, LPb3, Edg3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13610
VEGA: 13
HGNC: HGNC:3167
Homologene: 3829
Mllt3
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
Synonyms: 2210011H10Rik, D4Ertd321e, 3830408D16Rik, Af9, 2610012I03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70122
HGNC: HGNC:7136
Homologene: 37933
Trh
Name: thyrotropin releasing hormone
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22044
Homologene: 5163
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, D630001M17Rik, LOC381026, 9330188B09Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Zbtb14
Name: zinc finger and BTB domain containing 14
Synonyms: Zfp161, ZF5, b2b1982Clo
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22666
Homologene: 2560
Cacna2d3
Name: calcium channel, voltage-dependent, alpha2/delta subunit 3
Synonyms: alpha 2 delta-3, alpha2delta3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12294
Homologene: 74929
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: 9430095H01Rik, TEG-190, Tex190
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Med23
Name: mediator complex subunit 23
Synonyms: sno, ESTM7, X83317, Crsp3, Sur2, 3000002A17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Dpys
Name: dihydropyrimidinase
Synonyms: 1300004I01Rik, 1200017I10Rik, DHPase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 64705
HGNC: HGNC:3013
Homologene: 20359
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 252972
Homologene: 9905
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171395
Homologene: 51376
Clec4a2
Name: C-type lectin domain family 4, member a2
Synonyms: Clecsf6, Dcir1, dendritic cell immunoreceptor, DCIR
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26888
Homologene: 49291
Acat2
Name: acetyl-Coenzyme A acetyltransferase 2
Synonyms: Tcp-1x, Tcp1-rs1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 110460
HGNC: HGNC:94
Homologene: 55855
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 665700
Homologene: 90772
Prlr
Name: prolactin receptor
Synonyms: Pr-1, Prlr-rs1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19116
HGNC: HGNC:9446
Homologene: 733
Col9a2
Name: collagen, type IX, alpha 2
Synonyms: Col9a-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12840
HGNC: HGNC:2218
Homologene: 37535
Vwa3b
Name: von Willebrand factor A domain containing 3B
Synonyms: A230074B11Rik, 4921511C04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70853
Homologene: 27053
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53867
Homologene: 9253
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19886
Homologene: 2207
Caskin1
Name: CASK interacting protein 1
Synonyms: C630036E02Rik, 3300002N10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268932
VEGA: 17
Homologene: 25873
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Myom2
Name: myomesin 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Agap2
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Synonyms: Centg1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216439
VEGA: 10
Homologene: 86815
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 320277
Homologene: 23371
Dennd2d
Name: DENN domain containing 2D
Synonyms: 2010308M01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72121
Homologene: 11776
Klhl33
Name: kelch-like 33
Synonyms: EG546611
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 546611
VEGA: 14
Homologene: 52385
Pou2f2
Name: POU domain, class 2, transcription factor 2
Synonyms: Oct2d, Otf2, Oct2b, Oct2a, Oct-2, Otf-2, Oct2c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18987
HGNC: HGNC:9213
Homologene: 55674
Fbln5
Name: fibulin 5
Synonyms: EVEC
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23876
VEGA: 12
HGNC: HGNC:3602
Homologene: 38170
Tas2r144
Name: taste receptor, type 2, member 144
Synonyms: Tas2r44, mt2r33
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387515
Homologene: 47977
Sh3rf3
Name: SH3 domain containing ring finger 3
Synonyms: Sh3md4, 4831416G18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237353
Homologene: 77551
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Or52r1c
Name: olfactory receptor family 52 subfamily R member 1C
Synonyms: Olfr584, GA_x6K02T2PBJ9-5796876-5797820, MOR30-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259056
Man2b2
Name: mannosidase 2, alpha B2
Synonyms: 135 kDa alpha-D-mannosidase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17160
Homologene: 7411
Wars2
Name: tryptophanyl tRNA synthetase 2 (mitochondrial)
Synonyms: 9430020O07Rik, TrpRS
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70560
Homologene: 5673
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54667
Homologene: 23226
Cope
Name: coatomer protein complex, subunit epsilon
Synonyms: 1110005D17Rik, Cope1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 59042
HGNC: HGNC:2234
Homologene: 5254
Scgn
Name: secretagogin, EF-hand calcium binding protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214189
Homologene: 5088
Zdhhc16
Name: zinc finger, DHHC domain containing 16
Synonyms: Abl-philin 2, Ablphilin 2, 1500015N03Rik, APH2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74168
VEGA: 19
Homologene: 11377
Rbm7
Name: RNA binding motif protein 7
Synonyms: 1500011D06Rik, 1200007M24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67010
VEGA: 9
HGNC: HGNC:9904
Homologene: 9379
Gm16503
Name: predicted gene 16503
Type: Gene
Species: Mouse
Chromosome: 4
Sox18
Name: SRY (sex determining region Y)-box 18
Synonyms: Sry-related HMG-box gene 18, Ragl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20672
Homologene: 7546
Pcdhga10
Name: protocadherin gamma subfamily A, 10
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93722
HGNC: HGNC:8697
Homologene: 49567
Gm9195
Name: predicted gene 9195
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 675947
Homologene: 139067
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 37,114,534 bp (GRCm38)
  • A to G, chromosome 2 at 31,389,347 bp (GRCm38)
  • T to C, chromosome 2 at 181,670,438 bp (GRCm38)
  • A to T, chromosome 3 at 89,948,504 bp (GRCm38)
  • T to C, chromosome 3 at 99,187,530 bp (GRCm38)
  • T to A, chromosome 3 at 106,490,414 bp (GRCm38)
  • T to A, chromosome 4 at 87,873,931 bp (GRCm38)
  • T to A, chromosome 4 at 121,054,286 bp (GRCm38)
  • A to T, chromosome 4 at 147,541,051 bp (GRCm38)
  • A to G, chromosome 5 at 36,818,607 bp (GRCm38)
  • T to C, chromosome 5 at 120,540,672 bp (GRCm38)
  • A to T, chromosome 6 at 42,216,132 bp (GRCm38)
  • A to G, chromosome 6 at 92,243,842 bp (GRCm38)
  • G to T, chromosome 6 at 123,127,996 bp (GRCm38)
  • T to C, chromosome 7 at 16,839,902 bp (GRCm38)
  • G to A, chromosome 7 at 25,094,852 bp (GRCm38)
  • A to T, chromosome 7 at 81,300,679 bp (GRCm38)
  • A to T, chromosome 7 at 103,086,117 bp (GRCm38)
  • G to A, chromosome 8 at 15,084,633 bp (GRCm38)
  • T to C, chromosome 8 at 70,308,578 bp (GRCm38)
  • T to C, chromosome 9 at 20,793,613 bp (GRCm38)
  • T to C, chromosome 9 at 48,489,669 bp (GRCm38)
  • T to A, chromosome 10 at 24,912,807 bp (GRCm38)
  • A to G, chromosome 10 at 52,096,020 bp (GRCm38)
  • A to G, chromosome 10 at 59,130,980 bp (GRCm38)
  • G to C, chromosome 10 at 127,091,690 bp (GRCm38)
  • T to C, chromosome 11 at 8,836,399 bp (GRCm38)
  • T to A, chromosome 11 at 8,961,305 bp (GRCm38)
  • G to A, chromosome 12 at 101,771,292 bp (GRCm38)
  • T to A, chromosome 13 at 23,989,846 bp (GRCm38)
  • G to T, chromosome 13 at 51,419,517 bp (GRCm38)
  • A to T, chromosome 14 at 28,982,358 bp (GRCm38)
  • A to G, chromosome 14 at 50,896,446 bp (GRCm38)
  • A to G, chromosome 14 at 61,208,770 bp (GRCm38)
  • A to G, chromosome 14 at 72,480,060 bp (GRCm38)
  • T to A, chromosome 15 at 9,713,104 bp (GRCm38)
  • A to G, chromosome 15 at 10,328,902 bp (GRCm38)
  • T to C, chromosome 15 at 39,793,352 bp (GRCm38)
  • A to G, chromosome 15 at 91,700,415 bp (GRCm38)
  • G to A, chromosome 15 at 99,279,735 bp (GRCm38)
  • T to C, chromosome 16 at 20,656,691 bp (GRCm38)
  • T to C, chromosome 17 at 12,948,651 bp (GRCm38)
  • A to G, chromosome 17 at 24,504,473 bp (GRCm38)
  • T to C, chromosome 17 at 30,998,727 bp (GRCm38)
  • A to G, chromosome 17 at 69,388,581 bp (GRCm38)
  • G to T, chromosome 18 at 37,747,479 bp (GRCm38)
  • T to C, chromosome 19 at 41,938,110 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9341 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069152-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.