Strain Name:
C57BL/6J-MtgxR9346Btlr/Mmmh
Stock Number:
069157-MU
Citation ID:
RRID:MMRRC_069157-MU
Other Names:
R9346 (G1)
Major Collection:

Strain Information

Sbf2
Name: SET binding factor 2
Synonyms: B430219L04Rik, mMTMH1, 4833411B01Rik, SBF2, Mtmr13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: RNCAM, R4B12 antigen, Ncam-2, Ocam
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Cfl1
Name: cofilin 1, non-muscle
Synonyms: n-cofilin, Cof, cofilin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12631
HGNC: HGNC:1874
Homologene: 99735
Gtf2i
Name: general transcription factor II I
Synonyms: BAP-135, 6030441I21Rik, TFII-I
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 2610510B01Rik, 0610038M01Rik, Dopey2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Arid2
Name: AT-rich interaction domain 2
Synonyms: zipzap/p200, 1700124K17Rik, 4432409D24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77044
Homologene: 14601
Pon1
Name: paraoxonase 1
Synonyms: Pon
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18979
HGNC: HGNC:9204
Homologene: 68058
Adam8
Name: a disintegrin and metallopeptidase domain 8
Synonyms: CD156a, MS2, CD156, E430039A18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11501
HGNC: HGNC:215
Homologene: 74384
Zdhhc13
Name: zinc finger, DHHC domain containing 13
Synonyms: skc4, 2410004E01Rik, kojak, Hip14l
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243983
Homologene: 75106
Slc39a11
Name: solute carrier family 39 (metal ion transporter), member 11
Synonyms: 1810074D23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69806
Homologene: 12331
Rad51
Name: RAD51 recombinase
Synonyms: Reca, Rad51a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19361
HGNC: HGNC:9817
Homologene: 2155
Adh5
Name: alcohol dehydrogenase 5 (class III), chi polypeptide
Synonyms: Adh3, S-nitrosoglutathione reductase, Adh-5, GSNOR
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11532
HGNC: HGNC:253
Homologene: 68076
Tln1
Name: talin 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21894
Homologene: 21267
Ino80
Name: INO80 complex subunit
Synonyms: 2310079N15Rik, INO80, Inoc1, 4632409L19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68142
Homologene: 75070
Shq1
Name: SHQ1 homolog (S. cerevisiae)
Synonyms: 2810403P18Rik, Grim-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 72171
Homologene: 31683
Trim37
Name: tripartite motif-containing 37
Synonyms: MUL, TEF3, 1110032A10Rik, 2810004E07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68729
HGNC: HGNC:7523
Homologene: 9084
Dennd1a
Name: DENN domain containing 1A
Synonyms: 6030446I19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227801
Homologene: 17141
Zfp280b
Name: zinc finger protein 280B
Synonyms: Suhw2, D10Jhu82e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64453
VEGA: 10
Homologene: 62794
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: Cchl1a2, Cav1.3alpha1, 8430418G19Rik, Cchl1a, D-LTCC, Cacnl1a2, C79217
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Nynrin
Name: NYN domain and retroviral integrase containing
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 277154
VEGA: 14
Homologene: 19483
Chga
Name: chromogranin A
Synonyms: ChrA
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12652
VEGA: 12
HGNC: HGNC:1929
Homologene: 976
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Arnt2
Name: aryl hydrocarbon receptor nuclear translocator 2
Synonyms: bHLHe1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11864
Homologene: 7230
Arrb1
Name: arrestin, beta 1
Synonyms: 1200006I17Rik, beta-arrestin1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109689
HGNC: HGNC:711
Homologene: 2981
Ccdc180
Name: coiled-coil domain containing 180
Synonyms: E230008N13Rik, LOC381522
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381522
Homologene: 117988
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: 5730414M22Rik, Slo, MaxiK, BKCa, BK channel alpha subunit, mSlo1, Slo1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Sec11a
Name: SEC11 homolog A, signal peptidase complex subunit
Synonyms: sid2895, Spc18, 1810012E07Rik, 18kDa, Sec11l1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56529
Homologene: 55536
Or1e1c
Name: olfactory receptor family 1 subfamily E member 1C
Synonyms: MOR135-12, GA_x6K02T2P1NL-3535075-3536028, Olfr376
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258924
Homologene: 133579
Fam171a2
Name: family with sequence similarity 171, member A2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217219
Homologene: 19144
Adamts1
Name: ADAM metallopeptidase with thrombospondin type 1 motif 1
Synonyms: METH-1, ADAM-TS1, METH1, ADAMTS-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Or4c102
Name: olfactory receptor family 4 subfamily C member 102
Synonyms: Olfr1189, GA_x6K02T2Q125-50079044-50079964, MOR237-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258768
Homologene: 81569
Tgm6
Name: transglutaminase 6
Synonyms: TGM3L
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241636
Homologene: 27970
Ptk2b
Name: PTK2 protein tyrosine kinase 2 beta
Synonyms: Raftk, CAKbeta, cellular adhesion kinase beta, proline-rich tyrosine kinase 2, related adhesion focal tyrosine kinase, E430023O05Rik, PYK2, calcium-dependent tyrosine kinase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19229
HGNC: HGNC:9612
Homologene: 23001
Krt82
Name: keratin 82
Synonyms: Krt2-20
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 114566
VEGA: 15
HGNC: HGNC:6459
Homologene: 13200
Gimap9
Name: GTPase, IMAP family member 9
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 317758
Homologene: 115637
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Zgpat
Name: zinc finger, CCCH-type with G patch domain
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229007
Homologene: 41874
Brdt
Name: bromodomain, testis-specific
Synonyms: Fsrg3, 7420412D09Rik, Brd6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 114642
HGNC: HGNC:1105
Homologene: 21064
4930438A08Rik
Name: RIKEN cDNA 4930438A08 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73988
Homologene: 104884
Snrnp25
Name: small nuclear ribonucleoprotein 25 (U11/U12)
Synonyms: 3300001G02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78372
Homologene: 11592
Sftpd
Name: surfactant associated protein D
Synonyms: Sfpd, SP-D, Sftp4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 20390
VEGA: 14
Homologene: 2272
Aipl1
Name: aryl hydrocarbon receptor-interacting protein-like 1
Synonyms: A930007I01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 114230
HGNC: HGNC:359
Homologene: 22806
Zfp583
Name: zinc finger protein 583
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 213011
Homologene: 65048
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 2 at 38,021,435 bp (GRCm38)
  • T to A, chromosome 2 at 88,592,718 bp (GRCm38)
  • G to A, chromosome 2 at 119,118,612 bp (GRCm38)
  • G to A, chromosome 2 at 119,426,958 bp (GRCm38)
  • A to T, chromosome 2 at 130,141,856 bp (GRCm38)
  • C to A, chromosome 2 at 181,380,051 bp (GRCm38)
  • G to A, chromosome 3 at 138,451,442 bp (GRCm38)
  • C to A, chromosome 4 at 43,546,895 bp (GRCm38)
  • A to T, chromosome 4 at 45,927,953 bp (GRCm38)
  • T to C, chromosome 5 at 107,377,014 bp (GRCm38)
  • A to G, chromosome 5 at 134,244,809 bp (GRCm38)
  • G to T, chromosome 5 at 134,286,927 bp (GRCm38)
  • C to A, chromosome 6 at 5,193,722 bp (GRCm38)
  • C to A, chromosome 6 at 48,677,558 bp (GRCm38)
  • T to A, chromosome 6 at 100,664,470 bp (GRCm38)
  • T to A, chromosome 7 at 6,325,543 bp (GRCm38)
  • T to A, chromosome 7 at 48,822,580 bp (GRCm38)
  • T to C, chromosome 7 at 80,908,012 bp (GRCm38)
  • C to T, chromosome 7 at 84,282,113 bp (GRCm38)
  • T to A, chromosome 7 at 99,593,000 bp (GRCm38)
  • A to G, chromosome 7 at 110,320,739 bp (GRCm38)
  • T to C, chromosome 7 at 139,987,721 bp (GRCm38)
  • C to T, chromosome 10 at 76,039,292 bp (GRCm38)
  • A to T, chromosome 11 at 32,205,622 bp (GRCm38)
  • G to T, chromosome 11 at 58,288,269 bp (GRCm38)
  • C to T, chromosome 11 at 72,037,427 bp (GRCm38)
  • T to C, chromosome 11 at 73,375,303 bp (GRCm38)
  • A to T, chromosome 11 at 87,166,600 bp (GRCm38)
  • C to T, chromosome 11 at 102,437,945 bp (GRCm38)
  • A to G, chromosome 11 at 113,523,623 bp (GRCm38)
  • A to G, chromosome 12 at 102,559,289 bp (GRCm38)
  • T to C, chromosome 14 at 23,650,165 bp (GRCm38)
  • T to A, chromosome 14 at 30,096,923 bp (GRCm38)
  • C to T, chromosome 14 at 41,174,509 bp (GRCm38)
  • T to C, chromosome 14 at 55,494,684 bp (GRCm38)
  • A to G, chromosome 14 at 55,863,038 bp (GRCm38)
  • T to A, chromosome 14 at 66,178,092 bp (GRCm38)
  • T to C, chromosome 15 at 96,287,911 bp (GRCm38)
  • G to A, chromosome 15 at 99,279,735 bp (GRCm38)
  • A to G, chromosome 15 at 101,550,524 bp (GRCm38)
  • A to G, chromosome 16 at 81,455,316 bp (GRCm38)
  • T to A, chromosome 16 at 85,802,532 bp (GRCm38)
  • T to C, chromosome 16 at 93,780,814 bp (GRCm38)
  • T to A, chromosome 19 at 5,493,613 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9346 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069157-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.