Strain Name:
C57BL/6J-MtgxR9348Btlr/Mmmh
Stock Number:
069159-MU
Citation ID:
RRID:MMRRC_069159-MU
Other Names:
R9348 (G1)
Major Collection:

Strain Information

Kif3c
Name: kinesin family member 3C
Synonyms: N-4 kinesin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16570
VEGA: 12
HGNC: HGNC:6321
Homologene: 55640
Ranbp17
Name: RAN binding protein 17
Synonyms: 4932704E15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66011
Homologene: 36409
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224273
Homologene: 28544
Atp6v1h
Name: ATPase, H+ transporting, lysosomal V1 subunit H
Synonyms: 0710001F19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108664
Homologene: 7139
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Snd1
Name: staphylococcal nuclease and tudor domain containing 1
Synonyms: p100 co-activator, Tudor-SN
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56463
Homologene: 8665
Auts2
Name: autism susceptibility candidate 2
Synonyms: A730011F23Rik, D830032G16Rik, 2700063G02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319974
Homologene: 22907
Arfgef1
Name: ADP ribosylation factor guanine nucleotide exchange factor 1
Synonyms: BIG1, P200, ARFGEP1, D730028O18Rik, D130059B05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211673
Homologene: 4687
Icam5
Name: intercellular adhesion molecule 5, telencephalin
Synonyms: TLN, CD50, Tlcn, Icam3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15898
VEGA: 9
HGNC: HGNC:5348
Homologene: 2447
Arih2
Name: ariadne RBR E3 ubiquitin protein ligase 2
Synonyms: TRIAD1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23807
HGNC: HGNC:690
Homologene: 48424
Zfp141
Name: zinc finger protein 141
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434178
Creb3l1
Name: cAMP responsive element binding protein 3-like 1
Synonyms: BBF-2 (drosophila) homolog, Oasis
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26427
Homologene: 8058
Trim25
Name: tripartite motif-containing 25
Synonyms: Zfp147, estrogen-responsive finger protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217069
Homologene: 48325
Srpk2
Name: serine/arginine-rich protein specific kinase 2
Synonyms: WBP6, mSRPK2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20817
Homologene: 101663
Hs1bp3
Name: HCLS1 binding protein 3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 58240
VEGA: 12
Homologene: 10980
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: 9330197E15Rik, A630028O16Rik, LOC380767
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
E2f1
Name: E2F transcription factor 1
Synonyms: E2F-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13555
HGNC: HGNC:3113
Homologene: 3828
Cep164
Name: centrosomal protein 164
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214552
Homologene: 51110
Ttll7
Name: tubulin tyrosine ligase-like family, member 7
Synonyms: 1110049N09Rik, 4921517B04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70892
Homologene: 41578
Enpep
Name: glutamyl aminopeptidase
Synonyms: Ly51, aminopeptidase-A, 6030431M22Rik, APA, Bp-1/6C3, Ly-51
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13809
HGNC: HGNC:3355
Homologene: 68216
Prss45
Name: serine protease 45
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 260408
Homologene: 51905
Cyb5d1
Name: cytochrome b5 domain containing 1
Synonyms: LOC327951
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327951
Homologene: 15945
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241589
Homologene: 115928
Nlrp9b
Name: NLR family, pyrin domain containing 9B
Synonyms: Nalp9b, Nalp-delta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243874
Homologene: 18530
Stx2
Name: syntaxin 2
Synonyms: repro34, Syn-2, Epim, G1-536-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13852
HGNC: HGNC:3403
Homologene: 37559
BC034090
Name: cDNA sequence BC034090
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 207792
Homologene: 19490
Dennd5a
Name: DENN domain containing 5A
Synonyms: 1500012B19Rik, ORF37, Rab6ip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19347
Homologene: 14584
Adam25
Name: ADAM metallopeptidase domain 25
Synonyms: testase 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23793
HGNC: HGNC:199
Homologene: 128364
C4b
Name: complement C4B (Chido blood group)
Synonyms: Ss, C4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12268
Homologene: 36030
Zcchc9
Name: zinc finger, CCHC domain containing 9
Synonyms: 1810019C21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69085
Homologene: 12999
Cby2
Name: chibby family member 2
Synonyms: Spert, 1700086N05Rik, Nurit
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67926
VEGA: 14
Homologene: 12213
Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms: ether a go-go related, LQT, ERG1, Lqt2, merg1b, M-erg, merg1a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16511
HGNC: HGNC:6251
Homologene: 201
Prickle2
Name: prickle planar cell polarity protein 2
Synonyms: 6720451F06Rik, 6230400G14Rik, Pk2, mpk2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243548
Homologene: 17889
Cadps2
Name: Ca2+-dependent activator protein for secretion 2
Synonyms: cpd2, A230044C21Rik, Caps2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320405
Homologene: 23060
Ifi205
Name: interferon activated gene 205
Synonyms: D3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226695
Homologene: 115929
Bpifb9b
Name: BPI fold containing family B, member 9B
Synonyms: 5430413K10Rik, OTTMUSG00000015915
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 433492
Homologene: 128535
Tgfbrap1
Name: transforming growth factor, beta receptor associated protein 1
Synonyms: 3110018K12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73122
Homologene: 3141
Iqce
Name: IQ motif containing E
Synonyms: 1700028P05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74239
Homologene: 49912
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: Olfr136, GA_x6K02T2PSCP-2779375-2780313, MOR256-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Crlf1
Name: cytokine receptor-like factor 1
Synonyms: cytokine receptor like molecule 3, CLF-1, CRLM3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12931
HGNC: HGNC:2364
Homologene: 3489
Or2g1
Name: olfactory receptor family 2 subfamily G member 1
Synonyms: MOR256-9, GA_x6K02T2PSCP-2255106-2256035, Olfr123
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258623
Homologene: 105169
Oog2
Name: oogenesin 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381570
Homologene: 77858
Ndufaf3
Name: NADH:ubiquinone oxidoreductase complex assembly factor 3
Synonyms: 4733401H18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66706
Homologene: 32460
Zpbp2
Name: zona pellucida binding protein 2
Synonyms: 1700017D11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69376
Homologene: 18892
Cep112
Name: centrosomal protein 112
Synonyms: 1700001M19Rik, 1700029K01Rik, Ccdc46, 8430407H02Rik, Macoco
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76380
Homologene: 44915
Or1a1b
Name: olfactory receptor family 1 subfamily A member 1B
Synonyms: Olfr43, MOR125-1, GA_x6K02T2P1NL-4359899-4358958
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258706
Homologene: 8219
Preb
Name: prolactin regulatory element binding
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50907
HGNC: HGNC:9356
Homologene: 40877
Napepld
Name: N-acyl phosphatidylethanolamine phospholipase D
Synonyms: NAPE-PLD
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242864
Homologene: 7094
Or2w1
Name: olfactory receptor family 2 subfamily W member 1
Synonyms: GA_x6K02T2QHY8-12114828-12113875, Olfr42, IA3, Olfr263-ps1, GA_x6K02T2N5E5-9379-8514, MOR256-61, Olfr263, MOR256-37P, MOR256-31
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18341
HGNC: HGNC:8281
Homologene: 12791
Gm20939
Name: predicted gene, 20939
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100044193
VEGA: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 5,117,476 bp (GRCm38)
  • G to T, chromosome 1 at 10,213,194 bp (GRCm38)
  • A to G, chromosome 1 at 43,054,535 bp (GRCm38)
  • A to G, chromosome 1 at 155,223,303 bp (GRCm38)
  • T to C, chromosome 1 at 174,017,431 bp (GRCm38)
  • C to T, chromosome 2 at 91,991,886 bp (GRCm38)
  • T to C, chromosome 2 at 104,257,992 bp (GRCm38)
  • T to A, chromosome 2 at 154,318,846 bp (GRCm38)
  • T to A, chromosome 2 at 154,560,835 bp (GRCm38)
  • T to A, chromosome 3 at 129,309,123 bp (GRCm38)
  • T to A, chromosome 3 at 146,968,013 bp (GRCm38)
  • T to C, chromosome 4 at 144,195,219 bp (GRCm38)
  • A to T, chromosome 5 at 21,670,492 bp (GRCm38)
  • A to T, chromosome 5 at 23,514,673 bp (GRCm38)
  • C to T, chromosome 5 at 24,333,005 bp (GRCm38)
  • A to G, chromosome 5 at 30,955,651 bp (GRCm38)
  • A to G, chromosome 5 at 101,941,492 bp (GRCm38)
  • A to T, chromosome 5 at 128,999,537 bp (GRCm38)
  • T to C, chromosome 5 at 131,461,317 bp (GRCm38)
  • T to C, chromosome 5 at 140,691,625 bp (GRCm38)
  • T to C, chromosome 6 at 23,344,263 bp (GRCm38)
  • T to C, chromosome 6 at 28,745,207 bp (GRCm38)
  • C to T, chromosome 6 at 92,420,262 bp (GRCm38)
  • C to T, chromosome 7 at 20,023,411 bp (GRCm38)
  • C to A, chromosome 7 at 42,475,390 bp (GRCm38)
  • C to G, chromosome 7 at 109,899,723 bp (GRCm38)
  • T to A, chromosome 7 at 109,899,735 bp (GRCm38)
  • C to T, chromosome 8 at 40,755,916 bp (GRCm38)
  • T to A, chromosome 8 at 70,498,666 bp (GRCm38)
  • T to C, chromosome 9 at 21,032,131 bp (GRCm38)
  • T to C, chromosome 9 at 45,806,410 bp (GRCm38)
  • C to A, chromosome 9 at 108,566,158 bp (GRCm38)
  • C to G, chromosome 9 at 108,611,739 bp (GRCm38)
  • T to A, chromosome 9 at 110,839,210 bp (GRCm38)
  • T to C, chromosome 11 at 33,479,232 bp (GRCm38)
  • T to A, chromosome 11 at 69,395,004 bp (GRCm38)
  • T to A, chromosome 11 at 74,206,463 bp (GRCm38)
  • G to T, chromosome 11 at 89,009,341 bp (GRCm38)
  • C to T, chromosome 11 at 98,551,315 bp (GRCm38)
  • T to C, chromosome 11 at 108,437,250 bp (GRCm38)
  • A to G, chromosome 12 at 3,367,505 bp (GRCm38)
  • T to A, chromosome 12 at 8,336,273 bp (GRCm38)
  • T to C, chromosome 12 at 79,268,457 bp (GRCm38)
  • T to A, chromosome 13 at 21,132,961 bp (GRCm38)
  • T to A, chromosome 13 at 91,806,067 bp (GRCm38)
  • A to G, chromosome 14 at 75,583,398 bp (GRCm38)
  • T to C, chromosome 16 at 59,600,893 bp (GRCm38)
  • C to T, chromosome 17 at 34,733,185 bp (GRCm38)
  • T to C, chromosome 17 at 37,796,101 bp (GRCm38)
  • A to T, chromosome 17 at 38,335,429 bp (GRCm38)
  • A to G, chromosome 17 at 94,875,549 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9348 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069159-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.