Strain Name:
C57BL/6J-MtgxR9351Btlr/Mmmh
Stock Number:
069161-MU
Citation ID:
RRID:MMRRC_069161-MU
Other Names:
R9351 (G1)
Major Collection:

Strain Information

Nfat5
Name: nuclear factor of activated T cells 5
Synonyms: B130038B15Rik, TonEBP, nfatz, OREBP
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54446
HGNC: HGNC:7774
Homologene: 4811
Sf1
Name: splicing factor 1
Synonyms: Zfp162, MZFM, CW17R, WBP4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 22668
Homologene: 134065
Ippk
Name: inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Synonyms: 1810043M15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75678
VEGA: 13
Homologene: 41495
Adcy9
Name: adenylate cyclase 9
Synonyms: D16Wsu65e, ACtp10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11515
HGNC: HGNC:240
Homologene: 868
Ifi203
Name: interferon activated gene 203
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15950
HGNC: HGNC:5395
Homologene: 115929
Epb41l5
Name: erythrocyte membrane protein band 4.1 like 5
Synonyms: 1700030C16Rik, Lulu1, NBL5, Epb4.1l5, E230025E14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226352
Homologene: 32492
Brd1
Name: bromodomain containing 1
Synonyms: 1110059H06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223770
HGNC: HGNC:1102
Homologene: 40956
Zfp26
Name: zinc finger protein 26
Synonyms: Zfp-26, Zfp81-rs1, KRAB15, Zfp70, mkr-3, 5033428C05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22688
Homologene: 52318
Lars2
Name: leucyl-tRNA synthetase, mitochondrial
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102436
VEGA: 9
Homologene: 6526
Esr1
Name: estrogen receptor 1 (alpha)
Synonyms: Nr3a1, ESR, ER-alpha, ERalpha, Estr, ER[a], Estra, ERa
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13982
HGNC: HGNC:3467
Homologene: 47906
Iws1
Name: IWS1, SUPT6 interacting protein
Synonyms: 1700069O15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 73473
Homologene: 134421
Pus10
Name: pseudouridylate synthase 10
Synonyms: Ccdc139, 2810013G11Rik, 4933435A13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74467
Homologene: 12566
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: C130040G20Rik, Dbs
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17207
Homologene: 11804
Abca17
Name: ATP-binding cassette, sub-family A member 17
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381072
Homologene: 86807
Lctl
Name: lactase-like
Synonyms: E130104I05Rik, KLPH
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235435
Homologene: 70710
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: Dnchc2, m152Asp, m407Asp, b2b414Clo, D030010H02Rik, D330044F14Rik, 4432416O06Rik, DHC1b, DHC2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Rnf115
Name: ring finger protein 115
Synonyms: Rabring7, Zfp364, 2610028E05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67845
Homologene: 69167
Clp1
Name: CLP1, cleavage and polyadenylation factor I subunit
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98985
Homologene: 4975
Ahcyl1
Name: S-adenosylhomocysteine hydrolase-like 1
Synonyms: 1110034F20Rik, DCAL, IRBIT, Ahcy-rs3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229709
HGNC: HGNC:344
Homologene: 77353
Kdm2a
Name: lysine (K)-specific demethylase 2A
Synonyms: Cxxc8, Fbxl11, Jhdm1a, Fbl7, lalina, 5530401A10Rik, Gm4560
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225876
Homologene: 56564
Arhgef28
Name: Rho guanine nucleotide exchange factor 28
Synonyms: D13Bwg1089e, Rho specific exchange factor, 9230110L08Rik, RIP2, Rgnef, p190RhoGEF, RhoGEF
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110596
VEGA: 13
Homologene: 8078
Adamtsl3
Name: ADAMTS-like 3
Synonyms: punctin-2, 9230119C12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269959
Homologene: 18912
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, mKIAA0811, LOC245827, Fath2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
Vmn2r115
Name: vomeronasal 2, receptor 115
Synonyms: V2Rp4, EG638102
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 638102
Homologene: 86604
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56552
Homologene: 135915
Prr35
Name: proline rich 35
Synonyms: A930017K11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100034748
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Psd3
Name: pleckstrin and Sec7 domain containing 3
Synonyms: 4931420C21Rik, EFA6D
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234353
Homologene: 87257
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Stxbp5l
Name: syntaxin binding protein 5-like
Synonyms: tomosyn-2, A830015P08Rik, insulin level locus 1, LLGL4, t2md1, T2dm1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207227
Homologene: 18173
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: 4632417D23Rik, 9530025L16Rik, 5530401I02Rik, LOC268884
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 77446
Homologene: 35276
Irf5
Name: interferon regulatory factor 5
Synonyms: mirf5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27056
HGNC: HGNC:6120
Homologene: 8088
Tmprss15
Name: transmembrane protease, serine 15
Synonyms: Prss7, enterokinase, A130097D21Rik, enteropeptidase
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19146
HGNC: HGNC:9490
Homologene: 2075
Cabs1
Name: calcium binding protein, spermatid specific 1
Synonyms: 4931407G18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70977
Homologene: 13225
Mvp
Name: major vault protein
Synonyms: VAULT1, LRP, 2310009M24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78388
HGNC: HGNC:7531
Homologene: 3752
Eif4a3l1
Name: eukaryotic translation initiation factor 4A3 like 1
Synonyms: Gm8994, B020013A22Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 668137
Pcdhb2
Name: protocadherin beta 2
Synonyms: PcdhbB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93873
HGNC: HGNC:8687
Homologene: 69266
Ccdc96
Name: coiled-coil domain containing 96
Synonyms: 4921513E08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66717
Homologene: 32639
Zfp286
Name: zinc finger protein 286
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192651
Homologene: 56892
1700113H08Rik
Name: RIKEN cDNA 1700113H08 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76640
Homologene: 45695
Or6n2
Name: olfactory receptor family 6 subfamily N member 2
Synonyms: Olfr430, MOR105-5P, GA_x6K02T2P20D-21108443-21107490
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258713
Homologene: 17362
Wdr27
Name: WD repeat domain 27
Synonyms: 0610012K18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71682
VEGA: 17
Homologene: 18417
Tmed3
Name: transmembrane p24 trafficking protein 3
Synonyms: 1200002G13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66111
Homologene: 7213
Vmn1r30
Name: vomeronasal 1 receptor 30
Synonyms: V1rc9, V1rc22
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171195
Homologene: 137652
Parp8
Name: poly (ADP-ribose) polymerase family, member 8
Synonyms: D13Ertd275e, 2810430O08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 52552
VEGA: 13
Homologene: 11621
Kcnj12
Name: potassium inwardly-rectifying channel, subfamily J, member 12
Synonyms: IRK2, MB-IRK2, Kir2.2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16515
Homologene: 7793
Sdsl
Name: serine dehydratase-like
Synonyms: SDS-RS1, SDH1, 4432411H13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 257635
Homologene: 44224
Dcun1d1
Name: defective in cullin neddylation 1 domain containing 1
Synonyms: Rp42, pTes3, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae), SCCRO, Tes3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 114893
Homologene: 10773
Clgn
Name: calmegin
Synonyms: A2/6, calnexin-t, 4930459O04Rik, Cln
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12745
HGNC: HGNC:2060
Homologene: 68392
Map4k2
Name: mitogen-activated protein kinase kinase kinase kinase 2
Synonyms: BL44, Rab8ip
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 26412
HGNC: HGNC:6864
Homologene: 3370
Frmd3
Name: FERM domain containing 3
Synonyms: 4.1O, P410, 9430066I12Rik, EPB41L4O
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242506
Homologene: 16012
Pde6h
Name: phosphodiesterase 6H, cGMP-specific, cone, gamma
Synonyms: A930033D18Rik, PDEgamma
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78600
HGNC: HGNC:8790
Homologene: 4522
Gsto2
Name: glutathione S-transferase omega 2
Synonyms: 1700020F09Rik, 4930425C18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 68214
Homologene: 57057
Pagr1a
Name: PAXIP1 associated glutamate rich protein 1A
Synonyms: C77040, 2900092E17Rik, PA1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67278
Homologene: 11563
Trbv14
Name: T cell receptor beta, variable 14
Synonyms: Gm16910, BV13S1, Tcrb-V13
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100124678
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 119,549,909 bp (GRCm38)
  • A to G, chromosome 1 at 173,922,567 bp (GRCm38)
  • T to A, chromosome 1 at 174,069,455 bp (GRCm38)
  • T to C, chromosome 2 at 84,723,851 bp (GRCm38)
  • A to T, chromosome 3 at 35,921,036 bp (GRCm38)
  • T to C, chromosome 3 at 96,788,678 bp (GRCm38)
  • T to C, chromosome 3 at 107,667,695 bp (GRCm38)
  • A to G, chromosome 4 at 74,135,831 bp (GRCm38)
  • T to C, chromosome 5 at 36,484,725 bp (GRCm38)
  • A to G, chromosome 5 at 87,980,441 bp (GRCm38)
  • A to T, chromosome 5 at 120,463,094 bp (GRCm38)
  • A to T, chromosome 6 at 29,531,318 bp (GRCm38)
  • A to T, chromosome 6 at 41,135,494 bp (GRCm38)
  • A to G, chromosome 6 at 58,435,277 bp (GRCm38)
  • A to T, chromosome 6 at 124,039,374 bp (GRCm38)
  • A to T, chromosome 6 at 136,329,773 bp (GRCm38)
  • A to G, chromosome 6 at 136,959,334 bp (GRCm38)
  • A to T, chromosome 7 at 82,520,721 bp (GRCm38)
  • A to G, chromosome 7 at 126,996,263 bp (GRCm38)
  • A to T, chromosome 7 at 127,016,901 bp (GRCm38)
  • G to T, chromosome 8 at 13,000,757 bp (GRCm38)
  • T to C, chromosome 8 at 54,690,022 bp (GRCm38)
  • C to A, chromosome 8 at 67,960,649 bp (GRCm38)
  • A to G, chromosome 8 at 83,426,589 bp (GRCm38)
  • T to A, chromosome 8 at 107,339,278 bp (GRCm38)
  • G to A, chromosome 9 at 7,176,911 bp (GRCm38)
  • A to C, chromosome 9 at 20,438,151 bp (GRCm38)
  • T to C, chromosome 9 at 64,133,191 bp (GRCm38)
  • A to T, chromosome 9 at 89,702,927 bp (GRCm38)
  • A to G, chromosome 9 at 123,436,301 bp (GRCm38)
  • G to A, chromosome 10 at 4,746,763 bp (GRCm38)
  • G to A, chromosome 10 at 23,941,002 bp (GRCm38)
  • A to G, chromosome 10 at 87,230,206 bp (GRCm38)
  • A to G, chromosome 11 at 23,667,311 bp (GRCm38)
  • A to G, chromosome 11 at 55,281,301 bp (GRCm38)
  • C to T, chromosome 11 at 61,069,847 bp (GRCm38)
  • A to G, chromosome 11 at 62,779,975 bp (GRCm38)
  • C to T, chromosome 13 at 49,461,631 bp (GRCm38)
  • C to T, chromosome 13 at 97,994,068 bp (GRCm38)
  • G to T, chromosome 13 at 116,864,245 bp (GRCm38)
  • T to A, chromosome 15 at 88,730,104 bp (GRCm38)
  • A to T, chromosome 16 at 4,418,364 bp (GRCm38)
  • A to G, chromosome 16 at 33,725,497 bp (GRCm38)
  • A to G, chromosome 16 at 37,115,685 bp (GRCm38)
  • T to C, chromosome 16 at 79,035,198 bp (GRCm38)
  • G to A, chromosome 17 at 14,908,571 bp (GRCm38)
  • A to T, chromosome 17 at 23,359,508 bp (GRCm38)
  • G to A, chromosome 17 at 24,291,777 bp (GRCm38)
  • G to A, chromosome 17 at 25,947,144 bp (GRCm38)
  • G to A, chromosome 18 at 32,080,160 bp (GRCm38)
  • C to A, chromosome 18 at 37,296,316 bp (GRCm38)
  • C to T, chromosome 19 at 4,343,113 bp (GRCm38)
  • T to C, chromosome 19 at 6,351,193 bp (GRCm38)
  • A to G, chromosome 19 at 6,365,664 bp (GRCm38)
  • A to C, chromosome 19 at 9,007,868 bp (GRCm38)
  • T to A, chromosome 19 at 47,886,169 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9351 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069161-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.