Strain Name:
C57BL/6J-MtgxR9357Btlr/Mmmh
Stock Number:
069166-MU
Citation ID:
RRID:MMRRC_069166-MU
Other Names:
R9357 (G1)
Major Collection:

Strain Information

Agt
Name: angiotensinogen
Synonyms: Serpina8, angiotensin precursor, Aogen
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11606
HGNC: HGNC:333
Homologene: 14
Glo1
Name: glyoxalase 1
Synonyms: 2510049H23Rik, Qglo, Glo-1, 0610009E22Rik, Glo-1r, Glo-1s, Glo1-s, Glo1-r, 1110008E19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 109801
VEGA: 17
HGNC: HGNC:4323
Homologene: 4880
Map1b
Name: microtubule-associated protein 1B
Synonyms: Mtap1b, Mtap5, LC1, MAP5, Mtap-5
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: b2b1625.2Clo, D230004K18Rik, Megalin, Gp330
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 360013
Homologene: 7977
Cacul1
Name: CDK2 associated, cullin domain 1
Synonyms: 9830127L17Rik, 2700078E11Rik, 2810417M16Rik, D130033C15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78832
VEGA: 19
Homologene: 17821
Parg
Name: poly (ADP-ribose) glycohydrolase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 26430
HGNC: HGNC:8605
Homologene: 50532
Xdh
Name: xanthine dehydrogenase
Synonyms: XO, Xox1, Xor, Xox-1, xanthine oxidase
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Mindy1
Name: MINDY lysine 48 deubiquitinase 1
Synonyms: 4930504E06Rik, NF-E2 inducible protein, Fam63a, 1810005H09Rik, cI-40
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75007
Homologene: 32409
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2 (I blood group)
Synonyms: IGnTC, 5330430K10Rik, IGnTA, IGnTB, IGnT
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Twf2
Name: twinfilin actin binding protein 2
Synonyms: Ptk9l, A6-related, Twinfilin-2, Twf2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23999
HGNC: HGNC:9621
Homologene: 5272
Ppan
Name: peter pan homolog
Synonyms: A230087P06Rik, SSF1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235036
Homologene: 5690
Wdtc1
Name: WD and tetratricopeptide repeats 1
Synonyms: adipose, LOC230796, adp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230796
Homologene: 8997
Slc35d1
Name: solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Synonyms: UGTREL7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242585
Homologene: 22870
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Ush2a
Name: usherin
Synonyms: MUSH2A, LOC269160, Ush2a, A930037M10Rik, A930011D15Rik, LOC381317, Ushrn
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Fbxo24
Name: F-box protein 24
Synonyms: Fbx24, 4933422D21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71176
Homologene: 14131
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668940
Homologene: 66117
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Ppargc1b
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Synonyms: 4631412G21Rik, PGC-1beta/ERRL1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 170826
Homologene: 15776
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Sh3pxd2a
Name: SH3 and PX domains 2A
Synonyms: Sh3md1, 2310014D11Rik, Fish, Tks5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14218
VEGA: 19
Homologene: 7317
Atg4b
Name: autophagy related 4B, cysteine peptidase
Synonyms: Apg4b, autophagin 1, 2510009N07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66615
Homologene: 100868
Atp10b
Name: ATPase, class V, type 10B
Synonyms: 9030605H24Rik, 5930426O13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319767
Homologene: 70969
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, D130016K21Rik, 9430063L05Rik, Usmg4, 4732458A06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17836
HGNC: HGNC:9750
Homologene: 136663
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Gbp7
Name: guanylate binding protein 7
Synonyms: 9830147J24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229900
Homologene: 138296
Fpr-rs4
Name: formyl peptide receptor, related sequence 4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14291
HGNC: HGNC:3827
Homologene: 130629
Adam28
Name: a disintegrin and metallopeptidase domain 28
Synonyms: D430033C21Rik, MDC-L, Dtgn1, C130072N01Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 13522
VEGA: 14
HGNC: HGNC:206
Homologene: 40705
Apc2
Name: APC regulator of WNT signaling pathway 2
Synonyms: APCL
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23805
Homologene: 4299
Cnnm1
Name: cyclin M1
Synonyms: Acdp1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83674
VEGA: 19
HGNC: HGNC:102
Homologene: 10673
Ccdc7a
Name: coiled-coil domain containing 7A
Synonyms: 4930517G15Rik, 4930540C21Rik, Ccdc7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74703
Homologene: 134760
Tent5a
Name: terminal nucleotidyltransferase 5A
Synonyms: BAP014, D930050G01Rik, Fam46a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 212943
Homologene: 23032
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 675969
Homologene: 104330
Ifi213
Name: interferon activated gene 213
Synonyms: Pyr-A, Pydc4, E030037K03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 623121
HGNC: HGNC:5395
Homologene: 115929
Gsdmc4
Name: gasdermin C4
Synonyms: 9030605I04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74548
HGNC: HGNC:7151
Homologene: 69487
Vmn1r3
Name: vomeronasal 1 receptor 3
Synonyms: Gm11778
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100312471
Homologene: 128342
Zfp358
Name: zinc finger protein 358
Synonyms: Zfend
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 140482
Homologene: 9996
Ager
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 11596
HGNC: HGNC:320
Homologene: 883
Rdh16f2
Name: RDH16 family member 2
Synonyms: BC089597
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216454
Homologene: 129514
Pcdha6
Name: protocadherin alpha 6
Synonyms: Cnr2, Crnr2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12937
Homologene: 75098
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 93,785,926 bp (GRCm38)
  • T to A, chromosome 1 at 173,568,826 bp (GRCm38)
  • C to T, chromosome 1 at 188,874,950 bp (GRCm38)
  • T to C, chromosome 2 at 52,179,568 bp (GRCm38)
  • A to T, chromosome 2 at 69,506,573 bp (GRCm38)
  • A to G, chromosome 2 at 155,621,348 bp (GRCm38)
  • C to T, chromosome 3 at 95,295,279 bp (GRCm38)
  • A to G, chromosome 3 at 97,718,329 bp (GRCm38)
  • T to C, chromosome 3 at 142,543,128 bp (GRCm38)
  • T to G, chromosome 4 at 3,185,149 bp (GRCm38)
  • A to T, chromosome 4 at 103,208,136 bp (GRCm38)
  • A to G, chromosome 4 at 133,296,471 bp (GRCm38)
  • A to G, chromosome 5 at 137,612,834 bp (GRCm38)
  • T to C, chromosome 6 at 48,467,055 bp (GRCm38)
  • A to G, chromosome 6 at 121,875,491 bp (GRCm38)
  • A to G, chromosome 6 at 146,359,316 bp (GRCm38)
  • T to C, chromosome 7 at 86,231,220 bp (GRCm38)
  • T to C, chromosome 8 at 3,495,568 bp (GRCm38)
  • G to T, chromosome 8 at 124,564,326 bp (GRCm38)
  • T to C, chromosome 8 at 128,944,655 bp (GRCm38)
  • T to C, chromosome 9 at 20,889,924 bp (GRCm38)
  • A to T, chromosome 9 at 85,326,619 bp (GRCm38)
  • T to C, chromosome 9 at 106,214,901 bp (GRCm38)
  • T to C, chromosome 10 at 80,311,038 bp (GRCm38)
  • T to A, chromosome 10 at 127,877,046 bp (GRCm38)
  • A to G, chromosome 11 at 43,259,884 bp (GRCm38)
  • G to A, chromosome 11 at 59,038,766 bp (GRCm38)
  • C to T, chromosome 11 at 77,842,188 bp (GRCm38)
  • A to G, chromosome 11 at 120,010,870 bp (GRCm38)
  • A to G, chromosome 12 at 115,495,858 bp (GRCm38)
  • A to T, chromosome 13 at 40,888,256 bp (GRCm38)
  • A to T, chromosome 13 at 99,430,200 bp (GRCm38)
  • G to A, chromosome 14 at 32,274,917 bp (GRCm38)
  • C to T, chromosome 14 at 68,642,030 bp (GRCm38)
  • T to C, chromosome 15 at 63,900,347 bp (GRCm38)
  • T to A, chromosome 17 at 18,021,949 bp (GRCm38)
  • T to C, chromosome 17 at 30,612,544 bp (GRCm38)
  • T to C, chromosome 17 at 34,598,567 bp (GRCm38)
  • A to G, chromosome 17 at 73,907,716 bp (GRCm38)
  • A to C, chromosome 17 at 73,926,546 bp (GRCm38)
  • A to T, chromosome 18 at 31,960,076 bp (GRCm38)
  • A to T, chromosome 18 at 36,969,173 bp (GRCm38)
  • C to A, chromosome 18 at 61,315,868 bp (GRCm38)
  • A to C, chromosome 19 at 43,441,388 bp (GRCm38)
  • A to T, chromosome 19 at 47,272,009 bp (GRCm38)
  • A to G, chromosome 19 at 60,545,504 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9357 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069166-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.