Strain Name:
C57BL/6J-MtgxR9362Btlr/Mmmh
Stock Number:
069171-MU
Citation ID:
RRID:MMRRC_069171-MU
Other Names:
R9362 (G1)
Major Collection:

Strain Information

Adamts20
Name: ADAM metallopeptidase with thrombospondin type 1 motif 20
Synonyms: ADAMTS-20, bt
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223838
Homologene: 11808
Myh7
Name: myosin, heavy polypeptide 7, cardiac muscle, beta
Synonyms: MYH-beta/slow, beta-MHC, MyHC-I, B-MHC, Myhcb, Myhc-b, betaMHC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 140781
HGNC: HGNC:7577
Homologene: 68044
Ltbp3
Name: latent transforming growth factor beta binding protein 3
Synonyms: Ltbp2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16998
VEGA: 19
HGNC: HGNC:6716
Homologene: 7405
Gsr
Name: glutathione reductase
Synonyms: Gr1, Gr-1, D8Ertd238e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14782
HGNC: HGNC:4623
Homologene: 531
Ahdc1
Name: AT hook, DNA binding motif, containing 1
Synonyms: D030015G18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230793
Homologene: 17144
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, Phr1, C130061D10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Bmpr1a
Name: bone morphogenetic protein receptor, type 1A
Synonyms: Bmpr, ALK3, BMPR-IA, 1110037I22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12166
HGNC: HGNC:1076
Homologene: 20911
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: 4932438A13Rik, Tweek, FSA
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229227
Homologene: 52105
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRTe, SMRT
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Cnr1
Name: cannabinoid receptor 1
Synonyms: CB1R, CB1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12801
HGNC: HGNC:2159
Homologene: 7273
Arhgef17
Name: Rho guanine nucleotide exchange factor 17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207212
Homologene: 129601
Bcr
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, breakpoint cluster region
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110279
VEGA: 10
HGNC: HGNC:1014
Homologene: 3192
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: IGF-II/CI-MPR, CI-MPR, mannose-6-phosphate receptor, cation independent, M6P/IGF2R, Mpr300, CD222
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Zfp37
Name: zinc finger protein 37
Synonyms: Tzn, Zfp-37
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22696
Homologene: 40682
Tars1
Name: threonyl-tRNA synthetase 1
Synonyms: Tars, ThrRS, D15Wsu59e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110960
VEGA: 15
Homologene: 11852
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: C130096N06Rik, D130005J21Rik, Girdin, HkRP1, A430106J12Rik, C330012F17Rik, GIV
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108686
Homologene: 41180
Slc11a2
Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Synonyms: DMT1, Nramp2, van, DCT1, microcytic anemia, viable anaemia
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18174
Homologene: 55471
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Mapk3
Name: mitogen-activated protein kinase 3
Synonyms: Esrk1, p44 MAP kinase, Prkm3, Erk1, Mtap2k, Erk-1, p44mapk, p44erk1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26417
HGNC: HGNC:6877
Homologene: 55682
Snapc4
Name: small nuclear RNA activating complex, polypeptide 4
Synonyms: 5730436L13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227644
Homologene: 2321
Elmod1
Name: ELMO/CED-12 domain containing 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270162
VEGA: 9
Homologene: 10280
Il23r
Name: interleukin 23 receptor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209590
Homologene: 16930
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210274
Homologene: 105965
Myom1
Name: myomesin 1
Synonyms: D430047A17Rik, skelemin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319807
Homologene: 14974
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Galnt13
Name: polypeptide N-acetylgalactosaminyltransferase 13
Synonyms: pp-GalNAc-T13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271786
Homologene: 62167
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98733
Sidt1
Name: SID1 transmembrane family, member 1
Synonyms: B830021E24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320007
Homologene: 41189
Tead2
Name: TEA domain family member 2
Synonyms: TEF-4, TEAD-2, Etdf
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21677
Homologene: 19662
Gm10295
Name: predicted gene 10295
Type: Gene
Species: Mouse
Chromosome: 7
Hcfc2
Name: host cell factor C2
Synonyms: 1700129L13Rik, fkls
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67933
Homologene: 8337
Fam136a
Name: family with sequence similarity 136, member A
Synonyms: 2010309E21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66488
Homologene: 135942
Or8u8
Name: olfactory receptor family 8 subfamily U member 8
Synonyms: GA_x6K02T2Q125-47650922-47649963, Olfr52, IE6, MOR185-6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18352
Homologene: 105200
Slfn3
Name: schlafen 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20557
Homologene: 133236
Ggcx
Name: gamma-glutamyl carboxylase
Synonyms: vitamin K-dependent carboxylase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56316
HGNC: HGNC:4247
Homologene: 639
Slc5a12
Name: solute carrier family 5 (sodium/glucose cotransporter), member 12
Synonyms: SMCT2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241612
Homologene: 15107
Sall2
Name: spalt like transcription factor 2
Synonyms: Msal-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50524
Homologene: 9269
Gm5145
Name: predicted pseudogene 5145
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381065
VEGA: 17
Ighv5-8
Name: immunoglobulin heavy variable V5-8
Synonyms: Gm17309
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 777782
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 75,505,747 bp (GRCm38)
  • T to A, chromosome 2 at 26,364,853 bp (GRCm38)
  • A to G, chromosome 2 at 54,733,052 bp (GRCm38)
  • C to A, chromosome 2 at 86,181,388 bp (GRCm38)
  • C to T, chromosome 2 at 110,616,699 bp (GRCm38)
  • A to G, chromosome 3 at 36,957,013 bp (GRCm38)
  • T to C, chromosome 4 at 33,944,038 bp (GRCm38)
  • G to C, chromosome 4 at 47,288,200 bp (GRCm38)
  • G to A, chromosome 4 at 62,192,062 bp (GRCm38)
  • G to A, chromosome 4 at 133,063,037 bp (GRCm38)
  • G to T, chromosome 5 at 63,804,404 bp (GRCm38)
  • G to T, chromosome 5 at 94,303,142 bp (GRCm38)
  • C to T, chromosome 5 at 125,018,201 bp (GRCm38)
  • T to A, chromosome 6 at 67,423,400 bp (GRCm38)
  • T to G, chromosome 6 at 72,428,032 bp (GRCm38)
  • C to T, chromosome 6 at 86,368,873 bp (GRCm38)
  • A to G, chromosome 7 at 45,232,316 bp (GRCm38)
  • C to A, chromosome 7 at 71,351,007 bp (GRCm38)
  • A to C, chromosome 7 at 100,930,958 bp (GRCm38)
  • A to G, chromosome 7 at 126,764,272 bp (GRCm38)
  • C to T, chromosome 7 at 130,815,786 bp (GRCm38)
  • A to T, chromosome 7 at 144,409,534 bp (GRCm38)
  • A to T, chromosome 8 at 33,689,378 bp (GRCm38)
  • T to A, chromosome 9 at 53,926,020 bp (GRCm38)
  • C to A, chromosome 10 at 75,157,191 bp (GRCm38)
  • C to T, chromosome 10 at 82,738,424 bp (GRCm38)
  • T to A, chromosome 11 at 29,503,922 bp (GRCm38)
  • T to C, chromosome 11 at 83,212,981 bp (GRCm38)
  • A to T, chromosome 12 at 113,653,320 bp (GRCm38)
  • A to G, chromosome 14 at 34,434,403 bp (GRCm38)
  • T to A, chromosome 14 at 52,313,144 bp (GRCm38)
  • A to G, chromosome 14 at 54,985,475 bp (GRCm38)
  • C to T, chromosome 14 at 103,260,206 bp (GRCm38)
  • A to G, chromosome 15 at 11,387,530 bp (GRCm38)
  • T to A, chromosome 15 at 94,338,745 bp (GRCm38)
  • T to C, chromosome 15 at 100,406,355 bp (GRCm38)
  • T to C, chromosome 16 at 44,257,953 bp (GRCm38)
  • A to T, chromosome 17 at 12,722,175 bp (GRCm38)
  • A to G, chromosome 17 at 20,571,080 bp (GRCm38)
  • A to T, chromosome 17 at 71,036,293 bp (GRCm38)
  • A to G, chromosome 19 at 5,753,669 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9362 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069171-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.