Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9388Btlr/Mmmh
Stock Number:
069194-MU
Citation ID:
RRID:MMRRC_069194-MU
Other Names:
R9388 (G1)
Major Collection:

Strain Information

Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: GENA 60, GENA 47, Gena 52, Cyn, A730019I05Rik, WBE1, Whi, Todo, Obt, Mt, Lda, Flo, Edy, Dz, Cycn
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320790
Homologene: 19067
Il4
Name: interleukin 4
Synonyms: Il-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16189
HGNC: HGNC:6014
Homologene: 491
Mmp10
Name: matrix metallopeptidase 10
Synonyms: stromelysin 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17384
VEGA: 9
HGNC: HGNC:7156
Homologene: 20546
Xpnpep1
Name: X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Synonyms: D230045I08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 170750
Homologene: 6424
Herc4
Name: hect domain and RLD 4
Synonyms: 4921531D01Rik, 1700056O17Rik, 9530080M15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67345
VEGA: 10
Homologene: 56715
Ube2o
Name: ubiquitin-conjugating enzyme E2O
Synonyms: B230113M03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217342
Homologene: 11113
Stat1
Name: signal transducer and activator of transcription 1
Synonyms: 2010005J02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20846
Homologene: 21428
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 46,740,726 bp (GRCm38)
  • A to T, chromosome 1 at 52,153,878 bp (GRCm38)
  • C to A, chromosome 1 at 93,072,307 bp (GRCm38)
  • A to G, chromosome 1 at 138,083,642 bp (GRCm38)
  • T to C, chromosome 1 at 153,817,609 bp (GRCm38)
  • T to C, chromosome 1 at 157,560,823 bp (GRCm38)
  • A to T, chromosome 2 at 32,589,613 bp (GRCm38)
  • A to T, chromosome 2 at 87,093,046 bp (GRCm38)
  • A to T, chromosome 2 at 155,631,063 bp (GRCm38)
  • T to A, chromosome 3 at 106,488,599 bp (GRCm38)
  • A to G, chromosome 4 at 8,865,756 bp (GRCm38)
  • C to T, chromosome 4 at 113,192,641 bp (GRCm38)
  • A to G, chromosome 4 at 120,891,355 bp (GRCm38)
  • T to C, chromosome 4 at 150,642,610 bp (GRCm38)
  • T to A, chromosome 5 at 72,668,214 bp (GRCm38)
  • T to A, chromosome 5 at 105,813,996 bp (GRCm38)
  • T to A, chromosome 5 at 113,190,848 bp (GRCm38)
  • A to G, chromosome 6 at 38,731,021 bp (GRCm38)
  • T to C, chromosome 6 at 132,312,474 bp (GRCm38)
  • C to A, chromosome 7 at 3,658,368 bp (GRCm38)
  • C to T, chromosome 7 at 6,066,875 bp (GRCm38)
  • G to T, chromosome 7 at 103,250,938 bp (GRCm38)
  • A to G, chromosome 7 at 120,283,038 bp (GRCm38)
  • G to T, chromosome 7 at 140,539,015 bp (GRCm38)
  • G to A, chromosome 8 at 46,581,570 bp (GRCm38)
  • A to C, chromosome 8 at 55,872,250 bp (GRCm38)
  • A to T, chromosome 8 at 60,900,148 bp (GRCm38)
  • G to A, chromosome 9 at 7,504,169 bp (GRCm38)
  • A to G, chromosome 10 at 4,969,179 bp (GRCm38)
  • T to C, chromosome 10 at 18,630,129 bp (GRCm38)
  • T to C, chromosome 10 at 51,678,021 bp (GRCm38)
  • T to A, chromosome 10 at 63,307,743 bp (GRCm38)
  • A to G, chromosome 10 at 119,211,308 bp (GRCm38)
  • C to A, chromosome 11 at 34,262,460 bp (GRCm38)
  • C to T, chromosome 11 at 53,614,010 bp (GRCm38)
  • T to C, chromosome 11 at 59,052,663 bp (GRCm38)
  • C to T, chromosome 11 at 74,836,624 bp (GRCm38)
  • A to T, chromosome 11 at 98,710,067 bp (GRCm38)
  • T to C, chromosome 11 at 116,539,384 bp (GRCm38)
  • T to C, chromosome 12 at 31,491,568 bp (GRCm38)
  • T to C, chromosome 13 at 21,116,604 bp (GRCm38)
  • T to C, chromosome 13 at 55,476,275 bp (GRCm38)
  • C to T, chromosome 14 at 31,154,355 bp (GRCm38)
  • A to T, chromosome 16 at 23,079,638 bp (GRCm38)
  • T to C, chromosome 16 at 45,239,091 bp (GRCm38)
  • C to T, chromosome 16 at 91,495,479 bp (GRCm38)
  • A to G, chromosome 17 at 24,264,299 bp (GRCm38)
  • A to G, chromosome 17 at 25,247,135 bp (GRCm38)
  • A to G, chromosome 17 at 31,191,067 bp (GRCm38)
  • G to A, chromosome 17 at 33,777,184 bp (GRCm38)
  • C to T, chromosome 17 at 38,055,257 bp (GRCm38)
  • A to T, chromosome 18 at 37,505,800 bp (GRCm38)
  • A to G, chromosome 19 at 8,914,938 bp (GRCm38)
  • T to C, chromosome 19 at 53,004,802 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9388 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069194-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.