Strain Name:
C57BL/6J-MtgxR9413Btlr/Mmmh
Stock Number:
069217-MU
Citation ID:
RRID:MMRRC_069217-MU
Other Names:
R9413 (G1)
Major Collection:

Strain Information

Prrx1
Name: paired related homeobox 1
Synonyms: A230024N07Rik, mHox, Prx1, mHox, MHox1, Pmx1, K-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18933
HGNC: HGNC:9142
Homologene: 7896
Prkci
Name: protein kinase C, iota
Synonyms: 2310021H13Rik, Prkcl, Pkcl, aPKClambda, Pkci, PKClambda
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18759
HGNC: HGNC:9404
Homologene: 37667
Ppp1ca
Name: protein phosphatase 1 catalytic subunit alpha
Synonyms: dism2, Ppp1c
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19045
VEGA: 19
HGNC: HGNC:9281
Homologene: 105262
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: b2b327Clo, opm, A630086P08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Ubxn2b
Name: UBX domain protein 2B
Synonyms: 3110003A22Rik, 6430407D20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68053
Homologene: 23587
Atg13
Name: autophagy related 13
Synonyms: D2Ertd391e, 1110053A20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51897
Homologene: 32229
Gucy2c
Name: guanylate cyclase 2c
Synonyms: GC-C
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14917
HGNC: HGNC:4688
Homologene: 3641
D5Ertd579e
Name: DNA segment, Chr 5, ERATO Doi 579, expressed
Synonyms: 9030221A05Rik, A930018H20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320661
Homologene: 19716
Creb3l1
Name: cAMP responsive element binding protein 3-like 1
Synonyms: BBF-2 (drosophila) homolog, Oasis
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26427
Homologene: 8058
Snrnp27
Name: small nuclear ribonucleoprotein 27 (U4/U6.U5)
Synonyms: 2610209M04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66618
Homologene: 135794
Tubgcp3
Name: tubulin, gamma complex component 3
Synonyms: GCP3, Spc98p
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 259279
Homologene: 4609
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Ap3s1
Name: adaptor-related protein complex 3, sigma 1 subunit
Synonyms: [s]3A
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11777
VEGA: 18
HGNC: HGNC:2013
Homologene: 4254
Ell2
Name: elongation factor for RNA polymerase II 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 192657
VEGA: 13
Homologene: 8094
Arrdc2
Name: arrestin domain containing 2
Synonyms: 4632416I05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70807
Homologene: 79540
Mycbpap
Name: MYCBP associated protein
Synonyms: AMAP-1, 4932408B01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104601
Homologene: 49982
Chsy3
Name: chondroitin sulfate synthase 3
Synonyms: 4833446K15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 78923
VEGA: 18
Homologene: 28624
Vmn2r103
Name: vomeronasal 2, receptor 103
Synonyms: EG627636
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627636
Homologene: 115024
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 672511
Homologene: 45439
Trim69
Name: tripartite motif-containing 69
Synonyms: Rnf36, Trif, 4921519C19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70928
Homologene: 18827
Ephb6
Name: Eph receptor B6
Synonyms: Mep, Cekl
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Kif1a
Name: kinesin family member 1A
Synonyms: ATSV, N-3 kinesin, Kns1, LOC381283, C630002N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Pglyrp3
Name: peptidoglycan recognition protein 3
Synonyms: LOC242100
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242100
Homologene: 71559
Pex3
Name: peroxisomal biogenesis factor 3
Synonyms: 1700014F15Rik, 2810027F19Rik, 2900010N04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56535
HGNC: HGNC:8858
Homologene: 2691
C1qtnf4
Name: C1q and tumor necrosis factor related protein 4
Synonyms: 0710001E10Rik, 9430004J15Rik, CTRP4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67445
Homologene: 12134
Spata16
Name: spermatogenesis associated 16
Synonyms: Nyd-sp12, spermatogenesis-related protein, 4930503K02Rik, 4921511F01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70862
Homologene: 49974
Flnc
Name: filamin C, gamma
Synonyms: 1110055E19Rik, actin binding protein 280, Fln2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Psd4
Name: pleckstrin and Sec7 domain containing 4
Synonyms: EFA6B, SEC7 homolog
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 215632
Homologene: 8261
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: Olfr136, GA_x6K02T2PSCP-2779375-2780313, MOR256-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Cdk5rap1
Name: CDK5 regulatory subunit associated protein 1
Synonyms: 2310066P17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66971
Homologene: 9502
Akr7a5
Name: aldo-keto reductase family 7, member A5
Synonyms: 0610025K21Rik, Afar
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 110198
Homologene: 2737
Spag6
Name: sperm associated antigen 6
Synonyms: Spag6l, BC061194
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381350
Homologene: 133723
Gm6619
Name: predicted gene 6619
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 102638913
Homologene: 136510
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 93,021,297 bp (GRCm38)
  • A to G, chromosome 1 at 163,312,613 bp (GRCm38)
  • A to T, chromosome 2 at 18,734,218 bp (GRCm38)
  • C to T, chromosome 2 at 24,397,460 bp (GRCm38)
  • T to C, chromosome 2 at 90,890,304 bp (GRCm38)
  • T to C, chromosome 2 at 91,681,625 bp (GRCm38)
  • C to T, chromosome 2 at 91,991,886 bp (GRCm38)
  • G to A, chromosome 2 at 122,178,602 bp (GRCm38)
  • A to T, chromosome 2 at 154,365,960 bp (GRCm38)
  • T to A, chromosome 3 at 26,924,337 bp (GRCm38)
  • T to C, chromosome 3 at 31,043,766 bp (GRCm38)
  • G to T, chromosome 3 at 92,022,799 bp (GRCm38)
  • A to G, chromosome 4 at 6,204,607 bp (GRCm38)
  • A to T, chromosome 4 at 139,310,748 bp (GRCm38)
  • A to G, chromosome 5 at 36,614,934 bp (GRCm38)
  • G to A, chromosome 6 at 29,441,485 bp (GRCm38)
  • T to C, chromosome 6 at 41,614,575 bp (GRCm38)
  • T to C, chromosome 6 at 86,676,273 bp (GRCm38)
  • A to T, chromosome 6 at 131,491,407 bp (GRCm38)
  • T to C, chromosome 6 at 136,723,773 bp (GRCm38)
  • G to T, chromosome 7 at 81,478,009 bp (GRCm38)
  • A to T, chromosome 7 at 120,527,199 bp (GRCm38)
  • A to C, chromosome 8 at 12,624,885 bp (GRCm38)
  • C to T, chromosome 8 at 70,836,248 bp (GRCm38)
  • A to G, chromosome 10 at 13,534,710 bp (GRCm38)
  • A to G, chromosome 11 at 94,501,495 bp (GRCm38)
  • A to G, chromosome 11 at 119,466,233 bp (GRCm38)
  • G to A, chromosome 12 at 51,746,097 bp (GRCm38)
  • A to G, chromosome 13 at 75,769,586 bp (GRCm38)
  • A to G, chromosome 17 at 19,811,896 bp (GRCm38)
  • A to T, chromosome 17 at 38,335,429 bp (GRCm38)
  • T to C, chromosome 18 at 46,754,464 bp (GRCm38)
  • C to T, chromosome 18 at 59,176,098 bp (GRCm38)
  • T to C, chromosome 19 at 4,194,898 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9413 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069217-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.