Strain Name:
C57BL/6J-MtgxR9437Btlr/Mmmh
Stock Number:
069241-MU
Citation ID:
RRID:MMRRC_069241-MU
Other Names:
R9437 (G1)
Major Collection:

Strain Information

Mok
Name: MOK protein kinase
Synonyms: MAPK/MAK/MRK/ overlapping kinase, MOK, Stk30, Rage
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 26448
HGNC: HGNC:9833
Homologene: 8062
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: 2900024N03Rik, D930043C02Rik, 9430019J22Rik, Mnab, Rnf164
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319817
Homologene: 28276
Map4
Name: microtubule-associated protein 4
Synonyms: MAP 4, Mtap4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Etl4
Name: enhancer trap locus 4
Synonyms: Etl-4, Skt, E330027G05Rik, 9430077C05Rik, Sickle tail, 6620402G01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 208618
Homologene: 10477
Ccdc93
Name: coiled-coil domain containing 93
Synonyms: 9230102M16Rik, 4633402D15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70829
Homologene: 10393
Tex264
Name: testis expressed gene 264 ER-phagy receptor
Synonyms: TEG-264
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21767
Homologene: 7975
Kcnk5
Name: potassium channel, subfamily K, member 5
Synonyms: TASK-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16529
VEGA: 14
HGNC: HGNC:6280
Homologene: 2773
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Akap8l
Name: A kinase anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 54194
VEGA: 17
Homologene: 8658
Ncapd2
Name: non-SMC condensin I complex, subunit D2
Synonyms: 2810465G24Rik, 2810406C15Rik, CNAP1, CAP-D2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68298
Homologene: 6497
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: TAF3B1, Tfnr, TFC5, TFIIIB90, TFIIIB150, B130055N23Rik, G630013P12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 544971
Homologene: 34582
Krt10
Name: keratin 10
Synonyms: D130054E02Rik, cytokeratin 10, K1C1, Krt1-10, K10, keratin 10, suprabasal cytokeratin 10, Krt-1.10
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16661
HGNC: HGNC:6413
Homologene: 137236
Hnrnph3
Name: heterogeneous nuclear ribonucleoprotein H3
Synonyms: Hnrph3, hnRNP 2H9
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432467
HGNC: HGNC:5043
Homologene: 11012
Susd4
Name: sushi domain containing 4
Synonyms: E430021N18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 96935
Homologene: 23062
Peg10
Name: paternally expressed 10
Synonyms: Rtl2, MEF3L, MyEF-3, Mar2, MyEF-3 like, Edr, HB-1, Mart2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: C330025N11Rik, ZFYVE23
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232237
Homologene: 27798
Osbp2
Name: oxysterol binding protein 2
Synonyms: ORP-4, C630001G20Rik, OSBPL1, 1700095P05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74309
HGNC: HGNC:8504
Homologene: 75303
Nrp1
Name: neuropilin 1
Synonyms: NP-1, Npn1, NPN-1, Neuropilin-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18186
HGNC: HGNC:8004
Homologene: 2876
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: Arhgap13, 4930572H05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 117600
Homologene: 56898
Fscb
Name: fibrous sheath CABYR binding protein
Synonyms: EG623046
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 623046
VEGA: 12
Homologene: 136275
Pygl
Name: liver glycogen phosphorylase
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 110095
HGNC: HGNC:9725
Homologene: 84371
Cyp2b23
Name: cytochrome P450, family 2, subfamily b, polypeptide 23
Synonyms: EG243881
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243881
HGNC: HGNC:2615
Homologene: 117483
Or2w25
Name: olfactory receptor family 2 subfamily W member 25
Synonyms: Olfr225, MOR256-51, GA_x6K02T0073K-490-1545
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 257886
Homologene: 105324
Tbpl1
Name: TATA box binding protein-like 1
Synonyms: TRF2, TRP, TLF, Tlp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237336
Homologene: 3577
Pkn3
Name: protein kinase N3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263803
Homologene: 50980
Ebf4
Name: early B cell factor 4
Synonyms: Olf-1/EBF-like 4, O/E-4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228598
Homologene: 65064
Psg16
Name: pregnancy specific beta-1-glycoprotein 16
Synonyms: Cea11, bCEA
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26436
Ergic2
Name: ERGIC and golgi 2
Synonyms: 4930572C01Rik, 1200009B18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67456
Homologene: 6574
Fam24b
Name: family with sequence similarity 24 member B
Synonyms: 1700007K09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69318
Homologene: 78032
Ms4a3
Name: membrane-spanning 4-domains, subfamily A, member 3
Synonyms: HTm4, haematopoietic cell-specific transmembrane-4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 170813
HGNC: HGNC:7317
Homologene: 4472
Ly6c2
Name: lymphocyte antigen 6 family memberC2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 100041546
Homologene: 113718
Or56a41
Name: olfactory receptor family 56 subfamily A member 41, pseudogene 1
Synonyms: MOR40-10P, GA_x6K02T2PBJ9-7720330-7719479, Olfr680
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257981
Dcun1d2
Name: defective in cullin neddylation 1 domain containing 2
Synonyms: DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102323
Homologene: 85990
Pigx
Name: phosphatidylinositol glycan anchor biosynthesis, class X
Synonyms: 2010319C14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72084
Homologene: 9886
Pcdhga3
Name: protocadherin gamma subfamily A, 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93711
HGNC: HGNC:8701
Homologene: 75100
Gm2244
Name: predicted gene 2244
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100039452
Homologene: 115686
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 121,441,855 bp (GRCm38)
  • G to A, chromosome 1 at 172,104,145 bp (GRCm38)
  • T to C, chromosome 1 at 182,854,132 bp (GRCm38)
  • T to C, chromosome 2 at 20,809,061 bp (GRCm38)
  • T to C, chromosome 2 at 30,083,255 bp (GRCm38)
  • G to A, chromosome 2 at 37,382,829 bp (GRCm38)
  • T to A, chromosome 2 at 130,360,085 bp (GRCm38)
  • A to G, chromosome 3 at 38,891,268 bp (GRCm38)
  • T to TCCA, chromosome 6 at 4,756,451 bp (GRCm38)
  • A to G, chromosome 6 at 91,987,646 bp (GRCm38)
  • A to G, chromosome 6 at 125,176,692 bp (GRCm38)
  • T to C, chromosome 6 at 148,196,064 bp (GRCm38)
  • T to A, chromosome 7 at 17,093,790 bp (GRCm38)
  • A to T, chromosome 7 at 26,672,774 bp (GRCm38)
  • A to T, chromosome 7 at 105,090,756 bp (GRCm38)
  • A to T, chromosome 7 at 131,326,164 bp (GRCm38)
  • T to C, chromosome 8 at 13,281,004 bp (GRCm38)
  • A to G, chromosome 8 at 128,460,627 bp (GRCm38)
  • T to C, chromosome 9 at 106,681,897 bp (GRCm38)
  • C to A, chromosome 9 at 110,035,087 bp (GRCm38)
  • T to C, chromosome 10 at 22,711,939 bp (GRCm38)
  • T to A, chromosome 10 at 63,018,848 bp (GRCm38)
  • T to C, chromosome 10 at 121,800,872 bp (GRCm38)
  • A to G, chromosome 11 at 3,714,581 bp (GRCm38)
  • T to C, chromosome 11 at 59,613,369 bp (GRCm38)
  • A to G, chromosome 11 at 99,385,564 bp (GRCm38)
  • G to T, chromosome 12 at 64,472,934 bp (GRCm38)
  • A to G, chromosome 12 at 70,200,151 bp (GRCm38)
  • A to G, chromosome 12 at 110,808,225 bp (GRCm38)
  • A to G, chromosome 13 at 100,025,650 bp (GRCm38)
  • A to T, chromosome 14 at 19,548,970 bp (GRCm38)
  • A to C, chromosome 14 at 20,142,400 bp (GRCm38)
  • C to G, chromosome 15 at 75,111,686 bp (GRCm38)
  • G to T, chromosome 16 at 32,099,492 bp (GRCm38)
  • T to C, chromosome 17 at 32,334,634 bp (GRCm38)
  • G to A, chromosome 18 at 37,675,091 bp (GRCm38)
  • T to C, chromosome 19 at 11,629,701 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9437 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069241-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.