Strain Name:
C57BL/6J-MtgxR9438Btlr/Mmmh
Stock Number:
069242-MU
Citation ID:
RRID:MMRRC_069242-MU
Other Names:
R9438 (G1)
Major Collection:

Strain Information

Pax4
Name: paired box 4
Synonyms: Pax-4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18506
HGNC: HGNC:8618
Homologene: 4515
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Cdk19
Name: cyclin dependent kinase 19
Synonyms: 2700084L06Rik, Cdc2l6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 78334
VEGA: 10
Homologene: 22862
Usp7
Name: ubiquitin specific peptidase 7
Synonyms: 2210010O09Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 252870
Homologene: 2592
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: mXrn1, Dhm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24127
Homologene: 5894
Dnmt1
Name: DNA methyltransferase 1
Synonyms: MTase, Dnmt1o, Cxxc9, MommeD2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223666
Homologene: 27825
Dot1l
Name: DOT1 like histone lysine methyltransferase
Synonyms: mDot1, KMT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208266
Homologene: 32779
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, Drf1, Dia1, D18Wsu154e, mDia1, Diap1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Rexo1
Name: REX1, RNA exonuclease 1
Synonyms: 1700021P10Rik, 2610511M11Rik, Tceb3bp1, Rex1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66932
Homologene: 41391
Rufy3
Name: RUN and FYVE domain containing 3
Synonyms: 2810428M05Rik, 6330416M07Rik, D5Bwg0860e, Rpipx
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52822
Homologene: 87809
Ccdc93
Name: coiled-coil domain containing 93
Synonyms: 9230102M16Rik, 4633402D15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70829
Homologene: 10393
Rbbp6
Name: retinoblastoma binding protein 6, ubiquitin ligase
Synonyms: 4933422O15Rik, C030034J04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19647
HGNC: HGNC:9889
Homologene: 136812
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: mGluR7, Gpr1g, E130018M02Rik, 6330570A01Rik, mGlu7a receptor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Efs
Name: embryonal Fyn-associated substrate
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 13644
VEGA: 14
Homologene: 4284
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230895
Homologene: 15583
Nsd2
Name: nuclear receptor binding SET domain protein 2
Synonyms: 5830445G22Rik, 9430010A17Rik, Whsc1l, D030027O06Rik, C130020C13Rik, D930023B08Rik, Whsc1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 107823
Homologene: 26175
Muc16
Name: mucin 16
Synonyms: LOC385009, 1110008I14Rik, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Atp1b3
Name: ATPase, Na+/K+ transporting, beta 3 polypeptide
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11933
HGNC: HGNC:806
Homologene: 37510
Mrpl55
Name: mitochondrial ribosomal protein L55
Synonyms: 2810038N09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67212
Homologene: 12098
Trap1
Name: TNF receptor-associated protein 1
Synonyms: HSP75, 2410002K23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 68015
Homologene: 9457
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 5430439G14Rik, 6330406J24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71389
Homologene: 32772
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218333
VEGA: 13
Homologene: 18902
Papln
Name: papilin, proteoglycan-like sulfated glycoprotein
Synonyms: E030033C16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 170721
Homologene: 71541
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Setd1b
Name: SET domain containing 1B
Synonyms: KMT2G
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208043
Homologene: 134654
Rab44
Name: RAB44, member RAS oncogene family
Synonyms: 9830134C10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 442827
Homologene: 53300
Strc
Name: stereocilin
Synonyms: DFNB16
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 140476
Homologene: 15401
Cntn1
Name: contactin 1
Synonyms: F3cam, CNTN, usl
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12805
HGNC: HGNC:2171
Homologene: 7274
Tram2
Name: translocating chain-associating membrane protein 2
Synonyms: C330003D03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170829
Homologene: 8183
Pitpnm2
Name: phosphatidylinositol transfer protein, membrane-associated 2
Synonyms: RDGBA2, NIR3, Rdgb2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19679
Homologene: 7915
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: Slo, mSlo1, Slo1, MaxiK, BK channel alpha subunit, 5730414M22Rik, BKCa
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Rp1l1
Name: retinitis pigmentosa 1 homolog like 1
Synonyms: Dcdc4, Rp1hl1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 271209
VEGA: 14
Homologene: 105870
Cts6
Name: cathepsin 6
Synonyms: 1600022N02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 58518
Homologene: 75165
Or7e170
Name: olfactory receptor family 7 subfamily E member 170
Synonyms: GA_x6K02T2PVTD-13624132-13623212, MOR146-1, Olfr862
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258555
Homologene: 115540
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086, AI414108
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235086
Homologene: 19472
Tsks
Name: testis-specific serine kinase substrate
Synonyms: clone 4, Tssks1, Tsks, Stk22s1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22116
Homologene: 7984
Ttc14
Name: tetratricopeptide repeat domain 14
Synonyms: cI-44, 4931403I22Rik, 4930434D01Rik, 4933402I15Rik, 2700016E08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67120
Homologene: 12085
Ddt
Name: D-dopachrome tautomerase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13202
Homologene: 1038
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: SAPLT, 1700042F02Rik, 1700056N23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Nudcd1
Name: NudC domain containing 1
Synonyms: 4921532K09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67429
VEGA: 15
Homologene: 12128
Kbtbd12
Name: kelch repeat and BTB (POZ) domain containing 12
Synonyms: 4833415F11Rik, 4933428M03Rik, Klhdc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74589
Homologene: 52613
Terf2
Name: telomeric repeat binding factor 2
Synonyms: TRF2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21750
Homologene: 4133
Or7g19
Name: olfactory receptor family 7 subfamily G member 19
Synonyms: GA_x6K02T2PVTD-12687800-12688738, MOR153-1, Olfr832
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258075
HGNC: HGNC:8467
Homologene: 128143
Gbp11
Name: guanylate binding protein 11
Synonyms: Gm7141
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 634650
Homologene: 128731
Hecw1
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Synonyms: NEDL1, E130207I19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94253
VEGA: 13
Homologene: 9004
Nfkbib
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
Synonyms: IKappaBbeta, IkB
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18036
HGNC: HGNC:7798
Homologene: 37631
Plk5
Name: polo like kinase 5
Synonyms: 6330514A18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216166
Homologene: 28072
Adgra1
Name: adhesion G protein-coupled receptor A1
Synonyms: Gpr123, D7Ertd680e, 2900059M17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52389
Homologene: 18582
Or5p55
Name: olfactory receptor family 5 subfamily P member 55
Synonyms: GA_x6K02T2PBJ9-10296787-10297719, MOR204-3, Olfr476
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258926
Acp2
Name: acid phosphatase 2, lysosomal
Synonyms: Acp-2, LAP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11432
HGNC: HGNC:123
Homologene: 1217
Calhm5
Name: calcium homeostasis modulator family member 5
Synonyms: Fam26e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103511
VEGA: 10
Homologene: 17807
Cacng8
Name: calcium channel, voltage-dependent, gamma subunit 8
Synonyms: TARP gamma 8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81905
Homologene: 12894
Klri1
Name: killer cell lectin-like receptor family I member 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 503550
Homologene: 86735
Krt9
Name: keratin 9
Synonyms: K9, Krt1-9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107656
HGNC: HGNC:6447
Homologene: 138337
Tmod1
Name: tropomodulin 1
Synonyms: E-Tmod, erythrocyte tropomodulin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21916
Homologene: 20701
Prr23a4
Name: proline rich 23A, member 4
Synonyms: 7420426K07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 546157
Homologene: 133110
Ldhc
Name: lactate dehydrogenase C
Synonyms: Ldh-3, Ldh3, Ldhc4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16833
HGNC: HGNC:6544
Homologene: 22767
Tcstv5a
Name: Tcstv family member 5A
Synonyms: Tcstv5, B020031M17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 333467
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 21,005,610 bp (GRCm38)
  • A to G, chromosome 1 at 40,006,792 bp (GRCm38)
  • C to T, chromosome 1 at 121,441,855 bp (GRCm38)
  • T to C, chromosome 2 at 76,917,404 bp (GRCm38)
  • G to A, chromosome 2 at 91,202,994 bp (GRCm38)
  • A to T, chromosome 2 at 121,368,166 bp (GRCm38)
  • A to G, chromosome 2 at 160,957,158 bp (GRCm38)
  • T to A, chromosome 3 at 33,804,712 bp (GRCm38)
  • A to G, chromosome 4 at 46,093,958 bp (GRCm38)
  • G to T, chromosome 4 at 123,385,573 bp (GRCm38)
  • T to C, chromosome 4 at 145,131,744 bp (GRCm38)
  • A to G, chromosome 5 at 33,843,288 bp (GRCm38)
  • T to C, chromosome 5 at 88,648,265 bp (GRCm38)
  • T to A, chromosome 5 at 105,326,605 bp (GRCm38)
  • A to G, chromosome 5 at 123,147,881 bp (GRCm38)
  • G to A, chromosome 5 at 124,131,279 bp (GRCm38)
  • T to C, chromosome 6 at 28,446,186 bp (GRCm38)
  • G to A, chromosome 6 at 88,614,058 bp (GRCm38)
  • A to T, chromosome 6 at 111,254,116 bp (GRCm38)
  • A to C, chromosome 6 at 129,698,916 bp (GRCm38)
  • T to C, chromosome 6 at 146,166,668 bp (GRCm38)
  • G to A, chromosome 7 at 3,415,403 bp (GRCm38)
  • T to A, chromosome 7 at 28,760,229 bp (GRCm38)
  • C to T, chromosome 7 at 44,957,671 bp (GRCm38)
  • G to T, chromosome 7 at 46,866,433 bp (GRCm38)
  • A to T, chromosome 7 at 107,967,793 bp (GRCm38)
  • G to A, chromosome 7 at 123,000,233 bp (GRCm38)
  • C to T, chromosome 7 at 139,852,609 bp (GRCm38)
  • C to A, chromosome 8 at 107,076,872 bp (GRCm38)
  • T to C, chromosome 9 at 18,647,732 bp (GRCm38)
  • T to A, chromosome 9 at 18,945,030 bp (GRCm38)
  • C to T, chromosome 9 at 19,883,787 bp (GRCm38)
  • T to C, chromosome 9 at 20,915,894 bp (GRCm38)
  • T to C, chromosome 9 at 27,332,543 bp (GRCm38)
  • T to C, chromosome 9 at 96,011,234 bp (GRCm38)
  • A to T, chromosome 9 at 96,333,578 bp (GRCm38)
  • G to A, chromosome 9 at 98,903,780 bp (GRCm38)
  • T to C, chromosome 10 at 34,096,053 bp (GRCm38)
  • T to A, chromosome 10 at 40,476,180 bp (GRCm38)
  • A to T, chromosome 10 at 75,771,498 bp (GRCm38)
  • T to A, chromosome 10 at 80,358,033 bp (GRCm38)
  • C to T, chromosome 10 at 80,525,575 bp (GRCm38)
  • T to A, chromosome 10 at 80,543,014 bp (GRCm38)
  • T to A, chromosome 10 at 80,791,286 bp (GRCm38)
  • A to G, chromosome 11 at 59,205,755 bp (GRCm38)
  • G to T, chromosome 11 at 69,473,394 bp (GRCm38)
  • A to G, chromosome 11 at 100,188,998 bp (GRCm38)
  • A to T, chromosome 12 at 83,771,832 bp (GRCm38)
  • T to C, chromosome 13 at 14,306,829 bp (GRCm38)
  • G to A, chromosome 13 at 61,202,255 bp (GRCm38)
  • A to G, chromosome 13 at 70,606,315 bp (GRCm38)
  • A to G, chromosome 13 at 119,949,827 bp (GRCm38)
  • T to C, chromosome 14 at 23,367,585 bp (GRCm38)
  • T to A, chromosome 14 at 54,919,411 bp (GRCm38)
  • A to G, chromosome 14 at 64,028,125 bp (GRCm38)
  • C to T, chromosome 15 at 44,405,925 bp (GRCm38)
  • C to A, chromosome 15 at 76,751,918 bp (GRCm38)
  • G to A, chromosome 15 at 92,246,143 bp (GRCm38)
  • T to C, chromosome 16 at 4,065,267 bp (GRCm38)
  • T to C, chromosome 16 at 8,704,969 bp (GRCm38)
  • A to G, chromosome 17 at 29,145,252 bp (GRCm38)
  • A to C, chromosome 18 at 37,893,390 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9438 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069242-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.