Strain Name:
C57BL/6J-MtgxR9439Btlr/Mmmh
Stock Number:
069243-MU
Citation ID:
RRID:MMRRC_069243-MU
Other Names:
R9439 (G1)
Major Collection:

Strain Information

Avpr1b
Name: arginine vasopressin receptor 1B
Synonyms: V3/V1b, V1BR, AVPR3, V1bR, V3/V1b pituitary vasopressin receptor, VPR3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26361
HGNC: HGNC:896
Homologene: 22678
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: 0610010D24Rik, Daple
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68339
VEGA: 12
Homologene: 18903
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: KMT1D, 9230102N17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77683
Homologene: 11698
Armc9
Name: armadillo repeat containing 9
Synonyms: 5730415N24Rik, 4831423D23Rik, 3830422A13Rik, 4930438O05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78795
Homologene: 11847
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 328977
Homologene: 138627
Tcf7l1
Name: transcription factor 7 like 1 (T cell specific, HMG box)
Synonyms: Tcf3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21415
Homologene: 7563
Dot1l
Name: DOT1 like histone lysine methyltransferase
Synonyms: KMT4, mDot1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208266
Homologene: 32779
Cabin1
Name: calcineurin binding protein 1
Synonyms: Cain, Ppp3in, A330070M20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 104248
VEGA: 10
Homologene: 49307
Diaph1
Name: diaphanous related formin 1
Synonyms: mDia1, p140mDia, Drf1, Dia1, D18Wsu154e, Diap1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Tsc22d1
Name: TSC22 domain family, member 1
Synonyms: Egr5, Tgfb1i4, TSC-22
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21807
Homologene: 7573
Smpd4
Name: sphingomyelin phosphodiesterase 4
Synonyms: 4122402O22Rik, neutral membrane (neutral sphingomyelinase-3)
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 77626
Homologene: 9813
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: Pir121, 6430511D02Rik, 1500004I01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76884
Homologene: 7936
Gnat1
Name: G protein subunit alpha transducin 1
Synonyms: Gnat-1, Tralpha, Ird1, irdr, Ird2, transducin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14685
HGNC: HGNC:4393
Homologene: 20084
Rnf126
Name: ring finger protein 126
Synonyms: 2610010O19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70294
VEGA: 10
Homologene: 27024
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Mtnap1
Name: mitochondrial nucleoid associated protein 1
Synonyms: D11Wsu47e, Gm57859
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 276852
Homologene: 9928
Aak1
Name: AP2 associated kinase 1
Synonyms: 5530400K14Rik, D6Ertd245e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 269774
Homologene: 128746
Mpp7
Name: membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
Synonyms: 2810038M04Rik, 1110068J02Rik, LOC381166, 5430426E14Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75739
VEGA: 18
Homologene: 1455
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 4732496O19Rik, 6530407C02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99470
Homologene: 26431
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12870
HGNC: HGNC:2295
Homologene: 75
Gp2
Name: glycoprotein 2 zymogen granule membrane
Synonyms: 2310037I18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67133
HGNC: HGNC:4441
Homologene: 133790
Rfx8
Name: regulatory factor X 8
Synonyms: 4933400N17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 619289
Homologene: 82436
Il20ra
Name: interleukin 20 receptor, alpha
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237313
VEGA: 10
HGNC: HGNC:6003
Homologene: 8685
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
Synonyms: p150, Vps15
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75669
HGNC: HGNC:8982
Homologene: 24678
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: AS250, RGC2, A230067G21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241694
Homologene: 28131
Flt1
Name: FMS-like tyrosine kinase 1
Synonyms: vascular endothelial growth factor receptor-1, Flt-1, VEGFR1, VEGFR-1, sFlt1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14254
HGNC: HGNC:3763
Homologene: 134179
Rabl6
Name: RAB, member RAS oncogene family-like 6
Synonyms: Rbel1b, B230208H17Rik, Rbel1a, Rbel1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227624
Homologene: 11674
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
1110002E22Rik
Name: RIKEN cDNA 1110002E22 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 102634333
Homologene: 131709
Gm19410
Name: predicted gene, 19410
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 100502846
Homologene: 132117
Pitpnm2
Name: phosphatidylinositol transfer protein, membrane-associated 2
Synonyms: Rdgb2, RDGBA2, NIR3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19679
Homologene: 7915
Ache
Name: acetylcholinesterase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11423
HGNC: HGNC:108
Homologene: 543
Or51ac3
Name: olfactory receptor family 51 subfamily AC member 3
Synonyms: GA_x6K02T2PBJ9-6289676-6288723, Olfr616, MOR19-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259103
Homologene: 64957
Or5p81
Name: olfactory receptor family 5 subfamily P member 81
Synonyms: Olfr510, MOR204-34, GA_x6K02T2PBJ9-10997715-10998659
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258308
Ccnd2
Name: cyclin D2
Synonyms: cD2, Vin1, 2600016F06Rik, Vin-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12444
HGNC: HGNC:1583
Homologene: 37525
Or14j2
Name: olfactory receptor family 14 subfamily J member 2
Synonyms: GA_x6K02T2PSCP-2034880-2033942, MOR218-9, Olfr113
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258286
Ptk6
Name: PTK6 protein tyrosine kinase 6
Synonyms: Sik, Tksk
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20459
HGNC: HGNC:9617
Homologene: 68494
Nkx6-3
Name: NK6 homeobox 3
Synonyms: Nkx6.3, 9130417I07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74561
Homologene: 46375
Neil1
Name: nei endonuclease VIII-like 1 (E. coli)
Synonyms: 2810450N13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72774
Homologene: 11616
Paqr4
Name: progestin and adipoQ receptor family member IV
Synonyms: 1500004C10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 76498
VEGA: 17
Homologene: 22278
Vmn1r210
Name: vomeronasal 1 receptor 210
Synonyms: V1rh10
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171269
Homologene: 110880
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Tspoap1
Name: TSPO associated protein 1
Synonyms: peripheral, Bzrap1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207777
Homologene: 37961
Gpsm2
Name: G-protein signalling modulator 2 (AGS3-like, C. elegans)
Synonyms: 6230410J09Rik, LGN, Pins
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76123
Homologene: 56584
Prr23a2
Name: proline rich 23A, member 2
Synonyms: Gm6406
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 623186
Homologene: 67036
Plod3
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Synonyms: lysyl hydroxylase 3, LH3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26433
HGNC: HGNC:9083
Homologene: 843
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54667
Homologene: 23226
Or2h2c
Name: olfactory receptor family 2 subfamily H member 2C
Synonyms: MOR256-29, Olfr92, GA_x6K02T2PSCP-1552066-1551128
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258448
HGNC: HGNC:8253
Homologene: 115562
Or2t46
Name: olfactory receptor family 2 subfamily T member 46
Synonyms: MOR275-5, MOR275-11_p, Olfr325, GA_x6K02T2NKPP-844642-843680
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258261
Homologene: 133015
Gpc2
Name: glypican 2 cerebroglycan
Synonyms: 2410016G05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71951
HGNC: HGNC:4450
Homologene: 17657
Kap
Name: kidney androgen regulated protein
Synonyms: kidney androgen-regulated protein
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16483
Homologene: 49244
Or11m3
Name: olfactory receptor family 11 subfamily M member 3
Synonyms: Olfr279, GA_x6K02T04SN1-554-3, GA_x6K02T2NBG7-5241885-5241019, Olfr234, MOR122-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 258502
Homologene: 74008
Pcdha9
Name: protocadherin alpha 9
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 192161
HGNC: HGNC:8664
Homologene: 130700
Pcdhgb7
Name: protocadherin gamma subfamily B, 7
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93704
HGNC: HGNC:8714
Homologene: 75102
Noc2l
Name: NOC2 like nucleolar associated transcriptional repressor
Synonyms: NIR
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 57741
VEGA: 4
Homologene: 6980
Igkv4-80
Name: immunoglobulin kappa variable 4-80
Synonyms: Gm16729
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 545848
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to G, chromosome 1 at 39,685,509 bp (GRCm38)
  • T to C, chromosome 1 at 86,156,965 bp (GRCm38)
  • A to T, chromosome 1 at 90,816,433 bp (GRCm38)
  • T to C, chromosome 1 at 131,600,291 bp (GRCm38)
  • A to T, chromosome 2 at 24,825,018 bp (GRCm38)
  • C to T, chromosome 2 at 25,602,420 bp (GRCm38)
  • T to C, chromosome 2 at 146,412,138 bp (GRCm38)
  • T to A, chromosome 2 at 181,198,413 bp (GRCm38)
  • A to G, chromosome 3 at 19,992,507 bp (GRCm38)
  • T to A, chromosome 3 at 89,944,185 bp (GRCm38)
  • C to T, chromosome 3 at 104,015,157 bp (GRCm38)
  • T to A, chromosome 3 at 108,703,081 bp (GRCm38)
  • A to T, chromosome 3 at 138,066,287 bp (GRCm38)
  • T to C, chromosome 4 at 108,644,341 bp (GRCm38)
  • T to A, chromosome 4 at 156,241,673 bp (GRCm38)
  • A to G, chromosome 5 at 124,136,126 bp (GRCm38)
  • A to G, chromosome 5 at 124,140,596 bp (GRCm38)
  • G to A, chromosome 5 at 136,994,182 bp (GRCm38)
  • A to C, chromosome 5 at 137,290,923 bp (GRCm38)
  • G to T, chromosome 5 at 138,278,986 bp (GRCm38)
  • A to G, chromosome 5 at 147,578,397 bp (GRCm38)
  • T to A, chromosome 6 at 69,016,809 bp (GRCm38)
  • A to G, chromosome 6 at 72,788,757 bp (GRCm38)
  • T to C, chromosome 6 at 73,035,347 bp (GRCm38)
  • T to A, chromosome 6 at 86,956,292 bp (GRCm38)
  • A to T, chromosome 6 at 127,150,654 bp (GRCm38)
  • C to T, chromosome 6 at 133,851,987 bp (GRCm38)
  • C to A, chromosome 7 at 28,104,011 bp (GRCm38)
  • T to G, chromosome 7 at 103,564,842 bp (GRCm38)
  • T to C, chromosome 7 at 108,667,419 bp (GRCm38)
  • T to C, chromosome 7 at 119,454,210 bp (GRCm38)
  • A to G, chromosome 8 at 23,153,762 bp (GRCm38)
  • G to T, chromosome 8 at 35,781,656 bp (GRCm38)
  • T to A, chromosome 9 at 57,143,814 bp (GRCm38)
  • C to T, chromosome 9 at 98,856,868 bp (GRCm38)
  • C to A, chromosome 9 at 105,650,842 bp (GRCm38)
  • A to T, chromosome 9 at 107,676,312 bp (GRCm38)
  • C to A, chromosome 10 at 19,743,003 bp (GRCm38)
  • G to A, chromosome 10 at 75,745,235 bp (GRCm38)
  • G to A, chromosome 10 at 77,995,338 bp (GRCm38)
  • A to T, chromosome 10 at 79,761,631 bp (GRCm38)
  • G to T, chromosome 10 at 80,785,604 bp (GRCm38)
  • C to T, chromosome 11 at 46,200,841 bp (GRCm38)
  • T to C, chromosome 11 at 58,581,278 bp (GRCm38)
  • C to T, chromosome 11 at 87,774,709 bp (GRCm38)
  • C to T, chromosome 11 at 113,692,403 bp (GRCm38)
  • T to C, chromosome 12 at 100,918,338 bp (GRCm38)
  • A to C, chromosome 13 at 22,827,227 bp (GRCm38)
  • G to A, chromosome 14 at 76,506,459 bp (GRCm38)
  • T to C, chromosome 15 at 98,498,366 bp (GRCm38)
  • A to G, chromosome 16 at 17,641,587 bp (GRCm38)
  • A to G, chromosome 17 at 23,739,965 bp (GRCm38)
  • A to G, chromosome 17 at 37,111,313 bp (GRCm38)
  • A to G, chromosome 17 at 37,574,934 bp (GRCm38)
  • A to T, chromosome 18 at 7,461,692 bp (GRCm38)
  • A to G, chromosome 18 at 36,998,474 bp (GRCm38)
  • T to C, chromosome 18 at 37,751,864 bp (GRCm38)
  • A to G, chromosome 18 at 37,896,359 bp (GRCm38)
  • G to A, chromosome 18 at 65,685,643 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9439 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069243-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.