Strain Name:
C57BL/6J-MtgxR9461Btlr/Mmmh
Stock Number:
069264-MU
Citation ID:
RRID:MMRRC_069264-MU
Other Names:
R9461 (G1)
Major Collection:

Strain Information

Elp2
Name: elongator acetyltransferase complex subunit 2
Synonyms: Statip1, StIP1, Stat3-interacting protein
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 58523
VEGA: 18
Homologene: 6019
Arpp21
Name: cyclic AMP-regulated phosphoprotein, 21
Synonyms: 0710001E13Rik, Tarpp, R3hdm3, ARPP-21, D9Bwg1012e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74100
Homologene: 32306
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: Rutbc2, D5Bwg1524e, 2410098H20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52850
Homologene: 64485
Dock9
Name: dedicator of cytokinesis 9
Synonyms: D14Wsu89e, B230309H04Rik, Zizimin1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105445
Homologene: 41026
Tut7
Name: terminal uridylyl transferase 7
Synonyms: Tent3b, 6030448M23Rik, Zcchc6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Klhdc4
Name: kelch domain containing 4
Synonyms: G430025P05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234825
Homologene: 69234
Txnl1
Name: thioredoxin-like 1
Synonyms: 32kDa, TRP32
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 53382
VEGA: 18
Homologene: 3515
Serbp1
Name: serpine1 mRNA binding protein 1
Synonyms: 1200009K13Rik, 9330147J08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66870
Homologene: 134277
Phyhipl
Name: phytanoyl-CoA hydroxylase interacting protein-like
Synonyms: PHY2, 4921522K17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70911
Homologene: 13028
Zfp281
Name: zinc finger protein 281
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226442
Homologene: 8270
Syngap1
Name: synaptic Ras GTPase activating protein 1 homolog (rat)
Synonyms: Syngap
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240057
Homologene: 84739
Tars3
Name: threonyl-tRNA synthetase 3
Synonyms: A530046H20Rik, Tarsl2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 272396
Homologene: 65036
Mb21d2
Name: Mab-21 domain containing 2
Synonyms: 1600021P15Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239796
VEGA: 16
Homologene: 18614
Vat1
Name: vesicle amine transport 1
Synonyms: VAT-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26949
Homologene: 36200
Col24a1
Name: collagen, type XXIV, alpha 1
Synonyms: 5430404K19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71355
Homologene: 65061
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: A930014J19Rik, DMPK-like
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Lmod2
Name: leiomodin 2 (cardiac)
Synonyms: C-Lmod
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93677
HGNC: HGNC:6648
Homologene: 28302
Kif17
Name: kinesin family member 17
Synonyms: Kif17b, 5930435E01Rik, N-4 kinesin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16559
Homologene: 5883
Abcb9
Name: ATP-binding cassette, sub-family B member 9
Synonyms: TAPL
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56325
HGNC: HGNC:50
Homologene: 10491
Gas2l2
Name: growth arrest-specific 2 like 2
Synonyms: OTTMUSG00000000934
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237891
Homologene: 16409
Aox1
Name: aldehyde oxidase 1
Synonyms: Aox2, retinal oxidase, Aox-2, Aox-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11761
HGNC: HGNC:553
Homologene: 68165
Abhd18
Name: abhydrolase domain containing 18
Synonyms: 3110057O12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269423
Homologene: 105457
Thbs2
Name: thrombospondin 2
Synonyms: Thbs-2, TSP2, Thrombospondin-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Ces2b
Name: carboxyesterase 2B
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234669
HGNC: HGNC:1864
Homologene: 135851
Spem1
Name: spermatid maturation 1
Synonyms: 1700095G12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74288
Homologene: 45717
Tbc1d16
Name: TBC1 domain family, member 16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207592
Homologene: 10380
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Ranbp6
Name: RAN binding protein 6
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240614
HGNC: HGNC:9851
Homologene: 18935
Or5i1
Name: olfactory receptor family 5 subfamily I member 1
Synonyms: GA_x6K02T2Q125-49283184-49284128, Olfr4-1, MOR181-1, V1, Olfr152
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258640
HGNC: HGNC:8347
Homologene: 4835
Dab2
Name: disabled 2, mitogen-responsive phosphoprotein
Synonyms: D15Wsu122e, 5730435J12Rik, p96, D630005B22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13132
HGNC: HGNC:2662
Homologene: 1026
Cfap45
Name: cilia and flagella associated protein 45
Synonyms: Ccdc19, Nesg1, 1700028D05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71870
Homologene: 71837
Spsb1
Name: splA/ryanodine receptor domain and SOCS box containing 1
Synonyms: 4930422J18Rik, SSB1, 1110014L01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74646
Homologene: 11832
Pacs2
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: 6720425G15Rik, Pacs1l
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217893
VEGA: 12
Homologene: 15016
Veph1
Name: ventricular zone expressed PH domain-containing 1
Synonyms: Veph, 2810471M23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72789
Homologene: 11624
Mfsd4b3-ps
Name: major facilitator superfamily domain containing 4B3, pseudogene
Synonyms: G630090E17Rik, Mfsd4b3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 100041085
Homologene: 136347
Slc22a22
Name: solute carrier family 22 (organic cation transporter), member 22
Synonyms: BC026439, OAT-PG
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 210463
Homologene: 18166
Lrp8
Name: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Synonyms: Lr8b, 4932703M08Rik, apoER2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16975
HGNC: HGNC:6700
Homologene: 31250
Or52n2b
Name: olfactory receptor family 52 subfamily N member 2B
Synonyms: GA_x6K02T2PBJ9-7546146-7545166, MOR34-2, MOR34-11, Olfr667
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259062
Homologene: 121559
Zpld2
Name: zona pellucida like domain containing 2
Synonyms: Gm7534
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 665186
Homologene: 104039
Tmem220
Name: transmembrane protein 220
Synonyms: A730055C05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338369
Homologene: 18579
Or5b12b
Name: olfactory receptor family 5 subfamily B member 12B
Synonyms: MOR202-7, Olfr1445, GA_x6K02T2RE5P-3213352-3214296
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258694
Homologene: 133606
H1f7
Name: H1.7 linker histone
Synonyms: H1T2, 1700026P10Rik, H1fnt, H1-7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70069
VEGA: 15
Smpd1
Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Synonyms: A-SMase, ASM, Zn-SMase, aSMase, acid sphingomyelinase
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20597
Homologene: 457
Ppm1k
Name: protein phosphatase 1K (PP2C domain containing)
Synonyms: A930026L03Rik, PP2Cm, 2900063A19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243382
Homologene: 36819
Or14c41
Name: olfactory receptor family 14 subfamily C member 41
Synonyms: Olfr295, GA_x6K02T2NHDJ-9539243-9538314, MOR220-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258850
Homologene: 115526
Ccdc190
Name: coiled-coil domain containing 190
Synonyms: 1700084C01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78465
Homologene: 52274
Sfxn2
Name: sideroflexin 2
Synonyms: F630107H02Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94279
VEGA: 19
Homologene: 14227
Nkain2
Name: Na+/K+ transporting ATPase interacting 2
Synonyms: 6330571D19Rik, Tcba1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432450
Homologene: 65073
Sars2
Name: seryl-aminoacyl-tRNA synthetase 2
Synonyms: 2410015F05Rik, D7Ertd353e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71984
Homologene: 6073
Chst13
Name: carbohydrate sulfotransferase 13
Synonyms: Chst13, 1110067M19Rik, C4ST-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71797
Homologene: 44360
Dnajb1
Name: DnaJ heat shock protein family (Hsp40) member B1
Synonyms: Hsp40, 0610007I11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 81489
HGNC: HGNC:5270
Homologene: 55957
Eppk1
Name: epiplakin 1
Synonyms: EPPK, EPIPL1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223650
VEGA: 15
Homologene: 20006
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 58,077,577 bp (GRCm38)
  • T to A, chromosome 1 at 136,626,762 bp (GRCm38)
  • G to A, chromosome 1 at 169,933,920 bp (GRCm38)
  • A to G, chromosome 1 at 172,535,327 bp (GRCm38)
  • G to T, chromosome 1 at 180,142,296 bp (GRCm38)
  • A to T, chromosome 2 at 28,032,604 bp (GRCm38)
  • A to G, chromosome 2 at 87,782,539 bp (GRCm38)
  • A to T, chromosome 3 at 40,904,884 bp (GRCm38)
  • T to A, chromosome 3 at 66,121,645 bp (GRCm38)
  • G to T, chromosome 3 at 145,481,124 bp (GRCm38)
  • G to A, chromosome 4 at 107,843,318 bp (GRCm38)
  • G to A, chromosome 4 at 134,202,001 bp (GRCm38)
  • G to A, chromosome 4 at 138,277,942 bp (GRCm38)
  • A to T, chromosome 4 at 149,906,450 bp (GRCm38)
  • A to T, chromosome 5 at 113,276,032 bp (GRCm38)
  • T to C, chromosome 5 at 124,090,113 bp (GRCm38)
  • A to G, chromosome 6 at 24,603,569 bp (GRCm38)
  • T to C, chromosome 6 at 57,510,735 bp (GRCm38)
  • G to A, chromosome 6 at 67,267,329 bp (GRCm38)
  • G to A, chromosome 6 at 90,309,524 bp (GRCm38)
  • T to C, chromosome 7 at 28,750,013 bp (GRCm38)
  • T to C, chromosome 7 at 65,689,971 bp (GRCm38)
  • T to A, chromosome 7 at 86,586,039 bp (GRCm38)
  • T to A, chromosome 7 at 104,916,376 bp (GRCm38)
  • C to T, chromosome 7 at 105,555,582 bp (GRCm38)
  • T to C, chromosome 8 at 83,608,544 bp (GRCm38)
  • T to A, chromosome 8 at 104,837,379 bp (GRCm38)
  • T to C, chromosome 8 at 121,799,485 bp (GRCm38)
  • C to A, chromosome 9 at 112,136,636 bp (GRCm38)
  • C to T, chromosome 10 at 32,890,129 bp (GRCm38)
  • T to G, chromosome 10 at 39,947,251 bp (GRCm38)
  • T to C, chromosome 10 at 70,559,413 bp (GRCm38)
  • T to C, chromosome 11 at 67,034,153 bp (GRCm38)
  • T to C, chromosome 11 at 69,820,915 bp (GRCm38)
  • T to A, chromosome 11 at 83,422,205 bp (GRCm38)
  • T to C, chromosome 11 at 101,463,020 bp (GRCm38)
  • G to T, chromosome 11 at 119,153,955 bp (GRCm38)
  • A to G, chromosome 12 at 113,047,107 bp (GRCm38)
  • G to A, chromosome 13 at 59,815,698 bp (GRCm38)
  • C to T, chromosome 14 at 121,605,189 bp (GRCm38)
  • T to C, chromosome 15 at 6,430,954 bp (GRCm38)
  • T to C, chromosome 15 at 57,244,946 bp (GRCm38)
  • T to A, chromosome 15 at 57,263,656 bp (GRCm38)
  • T to C, chromosome 15 at 76,110,468 bp (GRCm38)
  • C to T, chromosome 15 at 98,257,257 bp (GRCm38)
  • C to T, chromosome 16 at 28,828,509 bp (GRCm38)
  • A to G, chromosome 17 at 14,690,173 bp (GRCm38)
  • T to A, chromosome 17 at 26,954,988 bp (GRCm38)
  • A to G, chromosome 18 at 24,632,812 bp (GRCm38)
  • T to C, chromosome 18 at 63,676,979 bp (GRCm38)
  • T to A, chromosome 19 at 12,884,511 bp (GRCm38)
  • T to C, chromosome 19 at 29,809,763 bp (GRCm38)
  • T to A, chromosome 19 at 46,585,753 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9461 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069264-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.