Strain Name:
C57BL/6J-MtgxR9470Btlr/Mmmh
Stock Number:
069273-MU
Citation ID:
RRID:MMRRC_069273-MU
Other Names:
R9470 (G1)
Major Collection:

Strain Information

Bmp7
Name: bone morphogenetic protein 7
Synonyms: OP1, osteogenic protein 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12162
HGNC: HGNC:1074
Homologene: 20410
Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: Nos-1, nNOS, 2310005C01Rik, bNOS, NO
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Ubap2
Name: ubiquitin-associated protein 2
Synonyms: 1190005K07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68926
Homologene: 73649
Zdbf2
Name: zinc finger, DBF-type containing 2
Synonyms: 4930431J08Rik, 9330107J05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73884
Homologene: 52868
Ggta1
Name: glycoprotein galactosyltransferase alpha 1, 3
Synonyms: Ggta-1, Gal, Ggta, glycoprotein alpha galactosyl transferase 1, GALT, alpha3GalT, alpha Gal
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14594
HGNC: HGNC:4253
Homologene: 7730
Arid1a
Name: AT-rich interaction domain 1A
Synonyms: Smarcf1, BAF250a, Osa1, 1110030E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 93760
Homologene: 21216
Tyw1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms: Rsafd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100929
Homologene: 7068
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 4432404J10Rik, 2010005B09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66691
Homologene: 32637
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665775
Homologene: 45109
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: D030002L11Rik, LOC382100, Rme8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235567
Homologene: 13574
Mov10l1
Name: Mov10 like RISC complex RNA helicase 1
Synonyms: CHAMP, Csm
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 83456
HGNC: HGNC:7201
Homologene: 56835
Barx2
Name: BarH-like homeobox 2
Synonyms: Barx2b, 2310006E12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12023
HGNC: HGNC:956
Homologene: 2715
Kcnu1
Name: potassium channel, subfamily U, member 1
Synonyms: Kcnma3, Slo3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16532
Homologene: 7392
Fam184b
Name: family with sequence similarity 184, member B
Synonyms: 9630031F12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 58227
Homologene: 137353
Scart2
Name: scavenger receptor family member expressed on T cells 2
Synonyms: 5830411N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244234
Homologene: 133218
Trim44
Name: tripartite motif-containing 44
Synonyms: Mc7, DIPB
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80985
Homologene: 9731
Zc3h12d
Name: zinc finger CCCH type containing 12D
Synonyms: D730019B10Rik, TFL
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237256
VEGA: 10
Homologene: 18225
Or6b6
Name: olfactory receptor family 6 subfamily B member 6
Synonyms: Olfr711, MOR103-4, GA_x6K02T2PBJ9-9352783-9351839
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259037
Homologene: 128111
Cyp2c54
Name: cytochrome P450, family 2, subfamily c, polypeptide 54
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 404195
VEGA: 19
Homologene: 137231
Ces1c
Name: carboxylesterase 1C
Synonyms: Es-4, Es-1, Ces-N, Es1, Ee-1, Es-N
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13884
HGNC: HGNC:1863
Homologene: 117484
Pcdhb14
Name: protocadherin beta 14
Synonyms: PcdhbN, Pcdhb17, 2210006M07Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93885
Homologene: 70876
Traf1
Name: TNF receptor-associated factor 1
Synonyms: 4732496E14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22029
Homologene: 4138
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229927
HGNC: HGNC:2017
Homologene: 135610
Noxred1
Name: NADP+ dependent oxidoreductase domain containing 1
Synonyms: 4933437F05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71275
VEGA: 12
Homologene: 51388
Nup50l
Name: nucleoporin 50 like
Synonyms: 1700123L14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78482
HGNC: HGNC:8065
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 636808
Homologene: 43974
Pde11a
Name: phosphodiesterase 11A
Synonyms: A630086N24Rik, 6330414F14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241489
HGNC: HGNC:8773
Homologene: 56763
Vmn1r47
Name: vomeronasal 1 receptor 47
Synonyms: V1ra4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113846
Homologene: 137651
Parp8
Name: poly (ADP-ribose) polymerase family, member 8
Synonyms: 2810430O08Rik, D13Ertd275e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 52552
VEGA: 13
Homologene: 11621
Tmem82
Name: transmembrane protein 82
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 213989
Homologene: 27088
Or5b113
Name: olfactory receptor family 5 subfamily B member 113
Synonyms: GA_x6K02T2RE5P-3695694-3696620, MOR202-15, Olfr1467
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258686
Homologene: 133888
Tmem156
Name: transmembrane protein 156
Synonyms: LOC243025
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243025
Homologene: 49811
Or11g1
Name: olfactory receptor family 11 subfamily G member 1
Synonyms: GA_x6K02T2PMLR-6110726-6111661, Olfr738, MOR106-3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258662
Homologene: 74220
Or5ak4
Name: olfactory receptor family 5 subfamily AK member 4
Synonyms: GA_x6K02T2Q125-46808500-46807571, MOR203-7P, Olfr987
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257951
Homologene: 103791
Or52j3
Name: olfactory receptor family 52 subfamily J member 3
Synonyms: GA_x6K02T2PBJ9-5902266-5903204, Olfr1525-ps1, MOR32-13, MOR0-3P, Olfr592, MOR0-3P
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404317
Homologene: 66215
Paqr7
Name: progestin and adipoQ receptor family member VII
Synonyms: PGLP, Mpra, 2310021M12Rik, mPR
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71904
Homologene: 12420
Zpbp
Name: zona pellucida binding protein
Synonyms: Sp38, 4930486K01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53604
Homologene: 5092
Nkx1-1
Name: NK1 homeobox 1
Synonyms: Nkx-1.1, Sax2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 672284
Homologene: 78303
Gpr31b
Name: G protein-coupled receptor 31, D17Leh66b region
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 436440
VEGA: 17
HGNC: HGNC:4486
Homologene: 48337
Potefam3e
Name: POTE ankyrin domain family member 3E
Synonyms: OTTMUSG00000018948, 4930467E23Rik, TSAP, ENSMUSG00000074453, Pote3e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 626415
Homologene: 128726
Sertad1
Name: SERTA domain containing 1
Synonyms: Trip-Br1, p34SEI-1, 1110032C13Rik, Sei-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 55942
Homologene: 8365
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 63,305,625 bp (GRCm38)
  • T to G, chromosome 1 at 116,446,614 bp (GRCm38)
  • A to T, chromosome 2 at 34,712,268 bp (GRCm38)
  • A to G, chromosome 2 at 34,943,962 bp (GRCm38)
  • T to C, chromosome 2 at 35,402,755 bp (GRCm38)
  • G to A, chromosome 2 at 75,991,268 bp (GRCm38)
  • A to T, chromosome 2 at 85,331,329 bp (GRCm38)
  • T to C, chromosome 2 at 102,400,306 bp (GRCm38)
  • G to T, chromosome 2 at 172,870,167 bp (GRCm38)
  • T to C, chromosome 3 at 144,837,695 bp (GRCm38)
  • G to A, chromosome 4 at 41,195,434 bp (GRCm38)
  • T to A, chromosome 4 at 130,009,281 bp (GRCm38)
  • T to C, chromosome 4 at 133,685,746 bp (GRCm38)
  • T to C, chromosome 4 at 134,507,603 bp (GRCm38)
  • T to A, chromosome 4 at 141,615,030 bp (GRCm38)
  • G to A, chromosome 5 at 33,433,931 bp (GRCm38)
  • A to T, chromosome 5 at 41,817,096 bp (GRCm38)
  • A to G, chromosome 5 at 45,584,512 bp (GRCm38)
  • C to T, chromosome 5 at 65,080,188 bp (GRCm38)
  • T to C, chromosome 5 at 117,926,495 bp (GRCm38)
  • G to A, chromosome 5 at 130,269,224 bp (GRCm38)
  • A to T, chromosome 6 at 84,113,370 bp (GRCm38)
  • T to G, chromosome 6 at 90,022,795 bp (GRCm38)
  • T to C, chromosome 6 at 96,165,493 bp (GRCm38)
  • T to C, chromosome 7 at 27,489,446 bp (GRCm38)
  • G to A, chromosome 7 at 103,187,063 bp (GRCm38)
  • A to T, chromosome 7 at 106,972,254 bp (GRCm38)
  • A to G, chromosome 7 at 140,247,432 bp (GRCm38)
  • T to A, chromosome 8 at 19,747,793 bp (GRCm38)
  • A to G, chromosome 8 at 25,919,632 bp (GRCm38)
  • C to T, chromosome 8 at 93,104,118 bp (GRCm38)
  • A to T, chromosome 9 at 31,858,748 bp (GRCm38)
  • A to G, chromosome 9 at 104,230,720 bp (GRCm38)
  • T to C, chromosome 10 at 7,867,557 bp (GRCm38)
  • A to T, chromosome 11 at 11,408,541 bp (GRCm38)
  • A to G, chromosome 12 at 7,989,219 bp (GRCm38)
  • A to G, chromosome 12 at 87,223,055 bp (GRCm38)
  • A to T, chromosome 13 at 116,894,756 bp (GRCm38)
  • T to C, chromosome 14 at 50,413,778 bp (GRCm38)
  • T to C, chromosome 15 at 89,020,315 bp (GRCm38)
  • A to G, chromosome 17 at 13,051,958 bp (GRCm38)
  • A to T, chromosome 18 at 37,448,023 bp (GRCm38)
  • A to G, chromosome 18 at 49,893,710 bp (GRCm38)
  • A to G, chromosome 19 at 13,364,751 bp (GRCm38)
  • T to C, chromosome 19 at 40,072,444 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9470 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069273-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.