Strain Name:
C57BL/6J-MtgxR9471Btlr/Mmmh
Stock Number:
069274-MU
Citation ID:
RRID:MMRRC_069274-MU
Other Names:
R9471 (G1)
Major Collection:

Strain Information

Clasrp
Name: CLK4-associating serine/arginine rich protein
Synonyms: SWAP2, Srsf16, Sfrs16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 53609
Homologene: 134306
Stoml1
Name: stomatin-like 1
Synonyms: UNC-24, WPB72, SLP-1, 1810015E19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69106
VEGA: 9
Homologene: 31265
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Mhdadsk9, Dsk9, Nf-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: LOC237877, C130052G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237877
Homologene: 32611
Anapc5
Name: anaphase-promoting complex subunit 5
Synonyms: 2510006G12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59008
Homologene: 41118
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382034
Homologene: 40964
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lec1, Lphn2, Lphh1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99633
Homologene: 22712
Tyw1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms: Rsafd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100929
Homologene: 7068
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214133
Homologene: 49498
Klhl24
Name: kelch-like 24
Synonyms: 4930429H24Rik, 1110046J11Rik, 6530402O20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 75785
VEGA: 16
Homologene: 32352
Mc5r
Name: melanocortin 5 receptor
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17203
VEGA: 18
HGNC: HGNC:6933
Homologene: 4321
Aff4
Name: AF4/FMR2 family, member 4
Synonyms: Laf4l, Alf4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 93736
Homologene: 8683
Bcl6
Name: B cell leukemia/lymphoma 6
Synonyms: Bcl5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12053
HGNC: HGNC:1001
Homologene: 7640
Zfp981
Name: zinc finger protein 981
Synonyms: Gm13247
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100041433
Homologene: 133076
Cd300lg
Name: CD300 molecule like family member G
Synonyms: D11Ertd736e, 2310016B05Rik, Clm9, nepmucin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 52685
Homologene: 17059
Alg12
Name: ALG12 alpha-1,6-mannosyltransferase
Synonyms: ECM39, mannosyltransferase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223774
Homologene: 36269
Klhl26
Name: kelch-like 26
Synonyms: C630013N10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234378
Homologene: 41247
Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Synonyms: HZF-3, RNR-1, Nurr1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18227
HGNC: HGNC:7981
Homologene: 4509
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Casp1
Name: caspase 1
Synonyms: Caspase-1, ICE, interleukin 1 beta-converting enzyme, Il1bc
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12362
VEGA: 9
HGNC: HGNC:1499
Homologene: 133272
Fcsk
Name: fucose kinase
Synonyms: Fuk, 1110046B12Rik, L-fucose kinase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234730
Homologene: 15452
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: Blimp-1, PRDI-BF1, Blimp1, b2b1765Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
Zscan18
Name: zinc finger and SCAN domain containing 18
Synonyms: EG232875
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232875
Homologene: 122136
Trim44
Name: tripartite motif-containing 44
Synonyms: Mc7, DIPB
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80985
Homologene: 9731
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242838
Homologene: 18247
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210274
Homologene: 105965
Egr4
Name: early growth response 4
Synonyms: pAT133, NGF1-C, NGFI-C
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13656
HGNC: HGNC:3241
Homologene: 1485
Pappa2
Name: pappalysin 2
Synonyms: PAPP-A2, placenta-specific 3, pregnancy-associated plasma protein-E, pregnancy-associated plasma preproprotein-A2, PLAC3, Pappe
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23850
Homologene: 10661
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338349
Homologene: 9805
Prss36
Name: serine protease 36
Synonyms: C330007D15Rik, polyserase-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77613
Homologene: 18303
Wdr90
Name: WD repeat domain 90
Synonyms: 3230401M21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106618
Homologene: 27066
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Pramel23
Name: PRAME like 23
Synonyms: Gm13089
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 277667
Actl6b
Name: actin-like 6B
Synonyms: ArpNa, Actl6, Baf53b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83766
HGNC: HGNC:160
Homologene: 81844
Hs6st3
Name: heparan sulfate 6-O-sulfotransferase 3
Synonyms: 6OST3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50787
VEGA: 14
Homologene: 89201
Mrc2
Name: mannose receptor, C type 2
Synonyms: uPARAP, Endo180, novel lectin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17534
Homologene: 4408
Pla2g6
Name: phospholipase A2, group VI
Synonyms: iPLA2beta, iPLA2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 53357
HGNC: HGNC:9039
Homologene: 2635
Klra5
Name: killer cell lectin-like receptor, subfamily A, member 5
Synonyms: Ly49e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16636
Homologene: 110821
Cd300c
Name: CD300C molecule
Synonyms: Clm6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 387565
Homologene: 74580
Tgm4
Name: transglutaminase 4 (prostate)
Synonyms: experimental autoimmune prostatitis antigen 1, 9530008N10Rik, Eapa1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 331046
Homologene: 20689
Pnpla1
Name: patatin-like phospholipase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 433091
Homologene: 25324
Frat2
Name: frequently rearranged in advanced T cell lymphomas 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 212398
Homologene: 8095
Zfp316
Name: zinc finger protein 316
Synonyms: Emzf1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54201
Homologene: 69231
Vmn2r67
Name: vomeronasal 2, receptor 67
Synonyms: EG620672
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620672
Homologene: 115466
Tmem156
Name: transmembrane protein 156
Synonyms: LOC243025
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243025
Homologene: 49811
Or1af1
Name: olfactory receptor family 1 subfamily AF member 1
Synonyms: Olfr366, MOR138-5P, MOR138-6, GA_x6K02T2NLDC-33902472-33903401
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 236509
Homologene: 114744
Apol7a
Name: apolipoprotein L 7a
Synonyms: 9130022K13Rik, Apol3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75761
HGNC: HGNC:619
Homologene: 40940
Clec4n
Name: C-type lectin domain family 4, member n
Synonyms: dectin-2, Nkcl, Clecsf10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56620
Homologene: 84615
Btbd7
Name: BTB domain containing 7
Synonyms: E130118E17Rik, 5730507E09Rik, FUP1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238386
VEGA: 12
Homologene: 34300
H2-M3
Name: histocompatibility 2, M region locus 3
Synonyms: Hmt, R4B2, H-2M3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14991
HGNC: HGNC:4964
Homologene: 133255
Obox2
Name: oocyte specific homeobox 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 246792
Homologene: 44937
Sbspon
Name: somatomedin B and thrombospondin, type 1 domain containing
Synonyms: LOC226866, Gm106
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226866
Homologene: 45950
Or2t48
Name: olfactory receptor family 2 subfamily T member 48
Synonyms: GA_x6K02T2NKPP-895420-896349, Olfr330, MOR275-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258879
Homologene: 133015
Defa29
Name: defensin, alpha, 29
Synonyms: 2010300L12Rik, CRS1C-2, Defcr-rs1, 2010319H24Rik, Defa-rs1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13218
Homologene: 85974
Atp6v1f
Name: ATPase, H+ transporting, lysosomal V1 subunit F
Synonyms: 1110004G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66144
Homologene: 3119
Fam221a
Name: family with sequence similarity 221, member A
Synonyms: D330028D13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 231946
Homologene: 18214
Ceacam13
Name: CEA cell adhesion molecule 13
Synonyms: Ceacam13-C2, 1600012K03Rik, 1600025J19Rik, Ceacam13-C1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69785
HGNC: HGNC:1819
Homologene: 135962
Ighv1-42
Name: immunoglobulin heavy variable V1-42
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629906
Sat2
Name: spermidine/spermine N1-acetyl transferase 2
Synonyms: SSAT2, SSAT-2, 2610016A03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69215
Homologene: 44215
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 15,892,453 bp (GRCm38)
  • C to T, chromosome 1 at 158,814,459 bp (GRCm38)
  • G to A, chromosome 2 at 37,220,388 bp (GRCm38)
  • A to G, chromosome 2 at 57,112,102 bp (GRCm38)
  • C to T, chromosome 2 at 76,768,502 bp (GRCm38)
  • T to C, chromosome 2 at 102,400,306 bp (GRCm38)
  • C to T, chromosome 3 at 133,485,919 bp (GRCm38)
  • T to C, chromosome 3 at 148,852,729 bp (GRCm38)
  • T to A, chromosome 4 at 85,049,782 bp (GRCm38)
  • T to A, chromosome 4 at 143,697,179 bp (GRCm38)
  • C to A, chromosome 4 at 146,537,623 bp (GRCm38)
  • A to T, chromosome 5 at 3,863,980 bp (GRCm38)
  • C to T, chromosome 5 at 65,080,188 bp (GRCm38)
  • T to C, chromosome 5 at 122,806,245 bp (GRCm38)
  • G to A, chromosome 5 at 130,269,224 bp (GRCm38)
  • A to G, chromosome 5 at 137,567,057 bp (GRCm38)
  • T to C, chromosome 5 at 143,255,406 bp (GRCm38)
  • T to A, chromosome 6 at 29,467,942 bp (GRCm38)
  • T to G, chromosome 6 at 49,372,586 bp (GRCm38)
  • A to G, chromosome 6 at 85,512,713 bp (GRCm38)
  • T to A, chromosome 6 at 123,244,546 bp (GRCm38)
  • C to A, chromosome 6 at 129,906,723 bp (GRCm38)
  • T to C, chromosome 7 at 12,774,416 bp (GRCm38)
  • G to A, chromosome 7 at 15,397,188 bp (GRCm38)
  • T to A, chromosome 7 at 18,019,087 bp (GRCm38)
  • G to A, chromosome 7 at 19,585,247 bp (GRCm38)
  • A to C, chromosome 7 at 85,150,515 bp (GRCm38)
  • A to T, chromosome 7 at 127,946,433 bp (GRCm38)
  • G to A, chromosome 7 at 144,411,015 bp (GRCm38)
  • T to C, chromosome 8 at 21,326,885 bp (GRCm38)
  • C to G, chromosome 8 at 70,452,153 bp (GRCm38)
  • T to C, chromosome 8 at 110,883,409 bp (GRCm38)
  • C to A, chromosome 8 at 120,575,106 bp (GRCm38)
  • G to A, chromosome 8 at 123,274,158 bp (GRCm38)
  • A to G, chromosome 9 at 5,304,187 bp (GRCm38)
  • A to T, chromosome 9 at 58,256,685 bp (GRCm38)
  • A to G, chromosome 9 at 123,040,379 bp (GRCm38)
  • C to T, chromosome 10 at 44,450,178 bp (GRCm38)
  • C to T, chromosome 11 at 53,380,646 bp (GRCm38)
  • A to T, chromosome 11 at 58,529,529 bp (GRCm38)
  • A to G, chromosome 11 at 69,622,899 bp (GRCm38)
  • A to G, chromosome 11 at 79,545,369 bp (GRCm38)
  • G to T, chromosome 11 at 80,132,698 bp (GRCm38)
  • T to A, chromosome 11 at 102,054,094 bp (GRCm38)
  • T to A, chromosome 11 at 105,343,733 bp (GRCm38)
  • A to T, chromosome 11 at 114,956,390 bp (GRCm38)
  • C to T, chromosome 12 at 102,793,886 bp (GRCm38)
  • T to A, chromosome 12 at 114,937,307 bp (GRCm38)
  • G to T, chromosome 14 at 119,138,823 bp (GRCm38)
  • A to G, chromosome 15 at 77,389,480 bp (GRCm38)
  • A to T, chromosome 15 at 79,317,839 bp (GRCm38)
  • G to A, chromosome 15 at 88,806,418 bp (GRCm38)
  • C to T, chromosome 16 at 20,122,985 bp (GRCm38)
  • T to A, chromosome 16 at 23,973,107 bp (GRCm38)
  • C to A, chromosome 17 at 25,861,041 bp (GRCm38)
  • A to T, chromosome 17 at 28,880,999 bp (GRCm38)
  • T to A, chromosome 17 at 37,271,097 bp (GRCm38)
  • A to G, chromosome 18 at 68,339,056 bp (GRCm38)
  • A to G, chromosome 19 at 41,847,674 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9471 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069274-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.