Strain Name:
C57BL/6J-MtgxR9473Btlr/Mmmh
Stock Number:
069276-MU
Citation ID:
RRID:MMRRC_069276-MU
Other Names:
R9473 (G1)
Major Collection:

Strain Information

Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: Edd1, Edd, 4432411E13Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 1810054D07Rik, 9130422G05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69863
Homologene: 25228
Rfx1
Name: regulatory factor X, 1 (influences HLA class II expression)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19724
HGNC: HGNC:9982
Homologene: 2189
Eif3l
Name: eukaryotic translation initiation factor 3, subunit L
Synonyms: PAF67, HSP-66Y, 0610011H21Rik, D15N1e, Eif3s6ip, Eif3eip
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223691
VEGA: 15
Homologene: 9380
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: binding factor for early enhancer, ESTM9, Cream1, MusTRD1, GTF3, WBSCR11, BEN
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 57080
HGNC: HGNC:4661
Homologene: 4158
Fip1l1
Name: factor interacting with PAPOLA and CPSF1
Synonyms: Rje, 1300019H17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66899
Homologene: 136254
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: enaptin165, nesprin-1, A330049M09Rik, C130039F11Rik, SYNE-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Dnmt3l
Name: DNA methyltransferase 3-like
Synonyms: ecat7, D6Ertd14e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54427
HGNC: HGNC:2980
Homologene: 8362
Slc18a3
Name: solute carrier family 18 (vesicular monoamine), member 3
Synonyms: VAChT, VAT
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 20508
Homologene: 11022
Akap5
Name: A kinase anchor protein 5
Synonyms: AKAP150, LOC238276, 3526401B18Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238276
HGNC: HGNC:375
Homologene: 15854
Nol11
Name: nucleolar protein 11
Synonyms: 1500002M01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68979
Homologene: 32264
Anapc10
Name: anaphase promoting complex subunit 10
Synonyms: Apc10, 1500026N15Rik, A830003M23Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68999
Homologene: 32238
Dpys
Name: dihydropyrimidinase
Synonyms: 1200017I10Rik, DHPase, 1300004I01Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 64705
HGNC: HGNC:3013
Homologene: 20359
Wscd1
Name: WSC domain containing 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216881
Homologene: 18590
Mturn
Name: maturin, neural progenitor differentiation regulator homolog (Xenopus)
Synonyms: B230212L03Rik, 2410066E13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68235
Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Synonyms: Nor1, MINOR, NOR-1, TEC
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18124
HGNC: HGNC:7982
Homologene: 5074
Bmf
Name: BCL2 modifying factor
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 171543
Homologene: 14130
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Capns2
Name: calpain, small subunit 2
Synonyms: 30K-2, 2310005G05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69543
Homologene: 57167
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, D430029O09Rik, 1110021D17Rik, Polydom
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64817
Homologene: 23386
Clcn3
Name: chloride channel, voltage-sensitive 3
Synonyms: Clc3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12725
HGNC: HGNC:2021
Homologene: 20435
Bltp2
Name: bridge-like lipid transfer protein family member 2
Synonyms: 2610507B11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72503
Homologene: 34730
Rdh19
Name: retinol dehydrogenase 19
Synonyms: Rdhs, RDH-S
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216453
Homologene: 129514
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238455
Homologene: 18813
Fbxl13
Name: F-box and leucine-rich repeat protein 13
Synonyms: 4921539K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320118
Homologene: 27057
Vpreb1b
Name: V-set pre-B cell surrogate light chain 1B
Synonyms: Vpreb-2, Vpreb2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22363
VEGA: 16
Homologene: 84741
Capn3
Name: calpain 3
Synonyms: p94, Capa-3, Lp82, Capa3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12335
HGNC: HGNC:1480
Homologene: 52
Plce1
Name: phospholipase C, epsilon 1
Synonyms: PLCepsilon, 4933403A21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74055
Homologene: 9478
Eif2b1
Name: eukaryotic translation initiation factor 2B, subunit alpha
Synonyms: EIF2B, EIF2BA, D5Ertd406e, 26kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 209354
HGNC: HGNC:3257
Homologene: 1080
Rflnb
Name: refilin B
Synonyms: RefilinB, Fam101b, cfm, 1500005K14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76566
Homologene: 18809
Steap1
Name: six transmembrane epithelial antigen of the prostate 1
Synonyms: 2410007B19Rik, Prss24
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70358
Homologene: 8256
Serpina1d
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1D
Synonyms: Spi1-4, PI4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20703
HGNC: HGNC:8941
Homologene: 20103
Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Synonyms: 1300012D20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71773
Homologene: 68144
Krt7
Name: keratin 7
Synonyms: Cytokeratin 7, K7, D15Wsu77e, Krt2-7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110310
HGNC: HGNC:6445
Homologene: 4058
Accsl
Name: 1-aminocyclopropane-1-carboxylate synthase (inactive)-like
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381411
Homologene: 86007
1700018F24Rik
Name: RIKEN cDNA 1700018F24 gene
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69396
Homologene: 86127
Abcc10
Name: ATP-binding cassette, sub-family C member 10
Synonyms: Mrp7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224814
HGNC: HGNC:52
Homologene: 58616
Gm17324
Name: predicted gene, 17324
Type: Gene
Species: Mouse
Chromosome: 9
Duoxa1
Name: dual oxidase maturation factor 1
Synonyms: Nip1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 213696
Homologene: 16043
Adgra2
Name: adhesion G protein-coupled receptor A2
Synonyms: Gpr124, 8430414O08Rik, Tem5, 9530074E10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78560
Homologene: 13112
Scgn
Name: secretagogin, EF-hand calcium binding protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214189
Homologene: 5088
Tpm2
Name: tropomyosin 2, beta
Synonyms: Trop-2, Tpm-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22004
Homologene: 134309
Dcstamp
Name: dendrocyte expressed seven transmembrane protein
Synonyms: Tm7sf4, DC-STAMP, 4833414I07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75766
VEGA: 15
Homologene: 12769
Galt
Name: galactose-1-phosphate uridyl transferase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14430
HGNC: HGNC:4135
Homologene: 126
Saxo5
Name: stabilizer of axonemal microtubules 5
Synonyms: 1700019B03Rik, Tex45
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76406
Homologene: 52367
Tas2r114
Name: taste receptor, type 2, member 114
Synonyms: T2R14, mt2r46, mGR14, Tas2r14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387346
Homologene: 128355
Ceacam13
Name: CEA cell adhesion molecule 13
Synonyms: Ceacam13-C2, 1600012K03Rik, 1600025J19Rik, Ceacam13-C1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69785
HGNC: HGNC:1819
Homologene: 135962
Ighv7-4
Name: immunoglobulin heavy variable 7-4
Synonyms: Gm16839
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 632654
HGNC: HGNC:5633
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 2 at 76,716,994 bp (GRCm38)
  • T to C, chromosome 2 at 93,855,747 bp (GRCm38)
  • A to C, chromosome 2 at 118,532,623 bp (GRCm38)
  • G to T, chromosome 2 at 120,496,054 bp (GRCm38)
  • A to G, chromosome 2 at 122,303,845 bp (GRCm38)
  • A to G, chromosome 4 at 41,757,575 bp (GRCm38)
  • A to T, chromosome 4 at 43,514,813 bp (GRCm38)
  • A to T, chromosome 4 at 48,052,143 bp (GRCm38)
  • A to G, chromosome 4 at 58,064,243 bp (GRCm38)
  • A to G, chromosome 4 at 83,263,740 bp (GRCm38)
  • T to G, chromosome 4 at 143,894,245 bp (GRCm38)
  • T to C, chromosome 5 at 5,740,378 bp (GRCm38)
  • T to C, chromosome 5 at 21,585,245 bp (GRCm38)
  • C to T, chromosome 5 at 74,585,058 bp (GRCm38)
  • A to T, chromosome 5 at 86,917,680 bp (GRCm38)
  • G to A, chromosome 5 at 124,574,614 bp (GRCm38)
  • T to A, chromosome 5 at 134,404,680 bp (GRCm38)
  • C to T, chromosome 5 at 145,044,102 bp (GRCm38)
  • G to A, chromosome 6 at 54,689,024 bp (GRCm38)
  • T to C, chromosome 6 at 131,689,141 bp (GRCm38)
  • G to T, chromosome 7 at 18,013,356 bp (GRCm38)
  • G to A, chromosome 8 at 3,479,232 bp (GRCm38)
  • T to A, chromosome 8 at 27,120,915 bp (GRCm38)
  • T to C, chromosome 8 at 60,954,617 bp (GRCm38)
  • A to G, chromosome 8 at 79,775,044 bp (GRCm38)
  • A to T, chromosome 8 at 84,093,274 bp (GRCm38)
  • T to C, chromosome 8 at 92,902,226 bp (GRCm38)
  • C to T, chromosome 9 at 53,498,972 bp (GRCm38)
  • G to T, chromosome 9 at 78,448,557 bp (GRCm38)
  • T to C, chromosome 10 at 5,248,258 bp (GRCm38)
  • C to T, chromosome 10 at 78,050,188 bp (GRCm38)
  • A to G, chromosome 10 at 127,860,308 bp (GRCm38)
  • A to G, chromosome 11 at 71,788,818 bp (GRCm38)
  • T to A, chromosome 11 at 76,022,238 bp (GRCm38)
  • G to A, chromosome 11 at 78,284,157 bp (GRCm38)
  • T to C, chromosome 11 at 107,184,755 bp (GRCm38)
  • T to C, chromosome 12 at 76,329,858 bp (GRCm38)
  • T to C, chromosome 12 at 103,763,680 bp (GRCm38)
  • T to C, chromosome 12 at 114,223,102 bp (GRCm38)
  • A to G, chromosome 12 at 119,334,255 bp (GRCm38)
  • T to C, chromosome 13 at 23,959,748 bp (GRCm38)
  • T to C, chromosome 14 at 32,463,956 bp (GRCm38)
  • A to G, chromosome 15 at 38,002,373 bp (GRCm38)
  • G to A, chromosome 15 at 39,754,576 bp (GRCm38)
  • A to G, chromosome 15 at 39,824,187 bp (GRCm38)
  • T to A, chromosome 15 at 79,086,504 bp (GRCm38)
  • C to T, chromosome 15 at 101,420,528 bp (GRCm38)
  • G to A, chromosome 16 at 17,980,701 bp (GRCm38)
  • T to C, chromosome 17 at 46,306,683 bp (GRCm38)
  • T to G, chromosome 18 at 90,590,969 bp (GRCm38)
  • A to T, chromosome 19 at 24,358,226 bp (GRCm38)
  • G to A, chromosome 19 at 38,777,893 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9473 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069276-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.