Strain Name:
C57BL/6J-MtgxR9481Btlr/Mmmh
Stock Number:
069284-MU
Citation ID:
RRID:MMRRC_069284-MU
Other Names:
R9481 (G1)
Major Collection:

Strain Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: HALR, E330008K23Rik, Mll3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Bdnf
Name: brain derived neurotrophic factor
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12064
HGNC: HGNC:1033
Homologene: 7245
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: 2810449C13Rik, D330022K21Rik, Usp31
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: Myst4, Morf, monocytic leukemia, qkf, querkopf, B130044K16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54169
Homologene: 136480
Vcl
Name: vinculin
Synonyms: metavinculin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22330
VEGA: 14
Homologene: 7594
Ccdc9
Name: coiled-coil domain containing 9
Synonyms: 2600011L02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243846
Homologene: 9209
Clasp2
Name: CLIP associating protein 2
Synonyms: 8030404L10Rik, CLASP2gamma, CLASP2beta, CLASP2, 1500004F14Rik, CLASP2alpha
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Grg1, Estm14, C230057C06Rik, Tle4l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21885
Homologene: 21058
Kcnk1
Name: potassium channel, subfamily K, member 1
Synonyms: TWIK-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16525
HGNC: HGNC:6272
Homologene: 1691
Arid1b
Name: AT-rich interaction domain 1B
Synonyms: 9330189K18Rik, B230217J03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 239985
Homologene: 32344
Nsmaf
Name: neutral sphingomyelinase (N-SMase) activation associated factor
Synonyms: factor associated with N-SMase activation, Fan
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18201
HGNC: HGNC:8017
Homologene: 2652
Hook1
Name: hook microtubule tethering protein 1
Synonyms: azh, abnormal spermatozoon head shape, A930033L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77963
Homologene: 9289
Icam5
Name: intercellular adhesion molecule 5, telencephalin
Synonyms: TLN, CD50, Tlcn, Icam3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15898
VEGA: 9
HGNC: HGNC:5348
Homologene: 2447
Ambn
Name: ameloblastin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11698
HGNC: HGNC:452
Homologene: 7625
Il15ra
Name: interleukin 15 receptor, alpha chain
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16169
HGNC: HGNC:5978
Homologene: 1650
Nmnat2
Name: nicotinamide nucleotide adenylyltransferase 2
Synonyms: D030041I09Rik, PNAT1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226518
Homologene: 75037
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 264895
Homologene: 23519
Gpc6
Name: glypican 6
Synonyms: 6720429C22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 23888
HGNC: HGNC:4454
Homologene: 55922
Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Synonyms: ESTM42, D3Ertd557e, bHLHe2, Hif1b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11863
HGNC: HGNC:700
Homologene: 1261
Pafah1b2
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
Synonyms: PAF-AH 30, mus[b], Pafahb, PAF-AH alpha2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18475
VEGA: 9
HGNC: HGNC:8575
Homologene: 1932
Srpra
Name: signal recognition particle receptor alpha
Synonyms: 1300011P19Rik, Srpr, D11Mgi27
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67398
Homologene: 2364
Ahcyl1
Name: S-adenosylhomocysteine hydrolase-like 1
Synonyms: 1110034F20Rik, DCAL, IRBIT, Ahcy-rs3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229709
HGNC: HGNC:344
Homologene: 77353
Zfp334
Name: zinc finger protein 334
Synonyms: D2Ertd535e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228876
Homologene: 23076
Cyp2r1
Name: cytochrome P450, family 2, subfamily r, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244209
Homologene: 75210
Efcab2
Name: EF-hand calcium binding domain 2
Synonyms: 1700073K01Rik, D830011E08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68226
Homologene: 12248
Cdh13
Name: cadherin 13
Synonyms: T-cadherin, 4932416G01Rik, Tcad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12554
HGNC: HGNC:1753
Homologene: 20335
Kctd19
Name: potassium channel tetramerisation domain containing 19
Synonyms: 4922504H04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 279499
Homologene: 18630
Megf10
Name: multiple EGF-like-domains 10
Synonyms: 3000002B06Rik, LOC240312
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70417
Homologene: 23771
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Abcb9
Name: ATP-binding cassette, sub-family B member 9
Synonyms: TAPL
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56325
HGNC: HGNC:50
Homologene: 10491
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Sez4, Rev
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Itga1
Name: integrin alpha 1
Synonyms: Vla1, CD49A, E130012M19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Hadhb
Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
Synonyms: Mtpb, 4930479F15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231086
HGNC: HGNC:4803
Homologene: 153
Vsig10l
Name: V-set and immunoglobulin domain containing 10 like
Synonyms: 2210412E05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75690
Homologene: 35386
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237711
Homologene: 104282
Cyba
Name: cytochrome b-245, alpha polypeptide
Synonyms: b558, p22 phox, cytochrome beta-558
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13057
HGNC: HGNC:2577
Homologene: 80
Spata17
Name: spermatogenesis associated 17
Synonyms: 1700065F16Rik, 4930504I07Rik, 4930513F16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74717
Homologene: 12551
Ptprb
Name: protein tyrosine phosphatase receptor type B
Synonyms: VE-PTP, 3230402H02Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 433070
Or2t1
Name: olfactory receptor family 2 subfamily T member 1
Synonyms: GA_x6K02T2PLTE-6714644-6715597, MTPCR53, MOR274-1, Olfr31
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18330
HGNC: HGNC:8277
Homologene: 74028
Or8g26
Name: olfactory receptor family 8 subfamily G member 26
Synonyms: Olfr943, GA_x6K02T2PVTD-32881408-32882343, MOR171-44
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258323
VEGA: 9
HGNC: HGNC:8484
Homologene: 110526
Fbln5
Name: fibulin 5
Synonyms: EVEC
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23876
VEGA: 12
HGNC: HGNC:3602
Homologene: 38170
Spef1
Name: sperm flagellar 1
Synonyms: 4931426K16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70997
Homologene: 15741
Skint9
Name: selection and upkeep of intraepithelial T cells 9
Synonyms: A030013N09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329918
Homologene: 136292
Or5w15
Name: olfactory receptor family 5 subfamily W member 15
Synonyms: Olfr1138, MOR177-8, GA_x6K02T2Q125-49242149-49241214
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258632
Homologene: 74082
Zpld2
Name: zona pellucida like domain containing 2
Synonyms: Gm7534
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 665186
Homologene: 104039
Vmn1r200
Name: vomeronasal 1 receptor 200
Synonyms: V1rh3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171246
Homologene: 110880
Rps6ka4
Name: ribosomal protein S6 kinase, polypeptide 4
Synonyms: 90kDa, MSK2, 1110069D02Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56613
VEGA: 19
Homologene: 69288
Stk32c
Name: serine/threonine kinase 32C
Synonyms: YANK3, Pkek
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57740
Homologene: 75157
Tmem88b
Name: transmembrane protein 88B
Synonyms: A230069A22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320587
Homologene: 85849
Cyp2a5
Name: cytochrome P450, family 2, subfamily a, polypeptide 5
Synonyms: Coh
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13087
Homologene: 85917
Glyatl3
Name: glycine-N-acyltransferase-like 3
Synonyms: Gm5683
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 435528
VEGA: 17
Homologene: 19824
Taar7d
Name: trace amine-associated receptor 7D
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 435206
Homologene: 115653
Or8b38
Name: olfactory receptor family 8 subfamily B member 38
Synonyms: MOR162-12, GA_x6K02T2PVTD-31740639-31741568, Olfr885
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257885
Homologene: 79400
Chst13
Name: carbohydrate sulfotransferase 13
Synonyms: 1110067M19Rik, Chst13, C4ST-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71797
Homologene: 44360
Scgb2b24
Name: secretoglobin, family 2B, member 24
Synonyms: Abpbg24, C2b, Abpz, Scgb2b3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233090
Homologene: 83171
Apol9b
Name: apolipoprotein L 9b
Synonyms: 2310016F22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71898
VEGA: 15
Homologene: 77567
Mettl21e
Name: methyltransferase like 21E
Synonyms: 4832428D23Rik, LOC381340
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 403183
Homologene: 19006
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 44,206,697 bp (GRCm38)
  • C to A, chromosome 1 at 153,086,435 bp (GRCm38)
  • T to C, chromosome 1 at 178,481,322 bp (GRCm38)
  • A to G, chromosome 1 at 187,112,559 bp (GRCm38)
  • T to C, chromosome 2 at 11,720,043 bp (GRCm38)
  • A to T, chromosome 2 at 87,738,232 bp (GRCm38)
  • A to G, chromosome 2 at 109,723,590 bp (GRCm38)
  • A to T, chromosome 2 at 131,172,705 bp (GRCm38)
  • G to A, chromosome 2 at 165,380,351 bp (GRCm38)
  • T to C, chromosome 3 at 95,483,781 bp (GRCm38)
  • A to T, chromosome 3 at 107,672,072 bp (GRCm38)
  • T to C, chromosome 4 at 6,414,976 bp (GRCm38)
  • G to A, chromosome 4 at 72,126,267 bp (GRCm38)
  • C to T, chromosome 4 at 96,013,268 bp (GRCm38)
  • A to T, chromosome 4 at 112,391,718 bp (GRCm38)
  • G to A, chromosome 4 at 134,202,001 bp (GRCm38)
  • G to A, chromosome 4 at 137,613,685 bp (GRCm38)
  • A to T, chromosome 4 at 155,784,276 bp (GRCm38)
  • A to T, chromosome 5 at 25,292,909 bp (GRCm38)
  • A to T, chromosome 5 at 25,349,862 bp (GRCm38)
  • T to G, chromosome 5 at 30,163,713 bp (GRCm38)
  • G to T, chromosome 5 at 88,465,191 bp (GRCm38)
  • A to G, chromosome 5 at 101,852,612 bp (GRCm38)
  • T to C, chromosome 5 at 124,090,113 bp (GRCm38)
  • G to A, chromosome 6 at 90,309,524 bp (GRCm38)
  • A to T, chromosome 7 at 16,282,836 bp (GRCm38)
  • A to C, chromosome 7 at 26,841,086 bp (GRCm38)
  • A to T, chromosome 7 at 33,737,370 bp (GRCm38)
  • G to T, chromosome 7 at 43,463,371 bp (GRCm38)
  • A to G, chromosome 7 at 114,553,134 bp (GRCm38)
  • G to A, chromosome 7 at 139,188,257 bp (GRCm38)
  • A to T, chromosome 8 at 105,393,617 bp (GRCm38)
  • A to G, chromosome 8 at 119,236,937 bp (GRCm38)
  • A to T, chromosome 8 at 122,427,655 bp (GRCm38)
  • T to C, chromosome 8 at 126,029,542 bp (GRCm38)
  • A to G, chromosome 9 at 21,037,581 bp (GRCm38)
  • C to T, chromosome 9 at 35,214,719 bp (GRCm38)
  • G to T, chromosome 9 at 38,061,411 bp (GRCm38)
  • T to C, chromosome 9 at 39,184,876 bp (GRCm38)
  • G to A, chromosome 9 at 45,972,986 bp (GRCm38)
  • A to T, chromosome 9 at 113,841,601 bp (GRCm38)
  • T to C, chromosome 10 at 24,027,841 bp (GRCm38)
  • T to A, chromosome 10 at 39,825,037 bp (GRCm38)
  • T to A, chromosome 10 at 116,319,448 bp (GRCm38)
  • T to G, chromosome 11 at 29,838,641 bp (GRCm38)
  • C to T, chromosome 11 at 94,573,218 bp (GRCm38)
  • A to T, chromosome 12 at 101,768,469 bp (GRCm38)
  • G to A, chromosome 13 at 13,683,068 bp (GRCm38)
  • T to A, chromosome 13 at 22,395,741 bp (GRCm38)
  • T to C, chromosome 13 at 115,016,217 bp (GRCm38)
  • C to T, chromosome 14 at 14,328,756 bp (GRCm38)
  • G to T, chromosome 14 at 21,020,658 bp (GRCm38)
  • AGAGGAGGAGGAGGAGGAGGA to AGAGGAGGAGGAGGAGGA, chromosome 14 at 21,662,349 bp (GRCm38)
  • A to G, chromosome 14 at 116,926,020 bp (GRCm38)
  • A to G, chromosome 15 at 47,607,063 bp (GRCm38)
  • G to T, chromosome 15 at 77,735,456 bp (GRCm38)
  • A to G, chromosome 17 at 5,318,732 bp (GRCm38)
  • A to G, chromosome 17 at 18,573,359 bp (GRCm38)
  • A to G, chromosome 17 at 40,910,125 bp (GRCm38)
  • T to A, chromosome 18 at 57,262,018 bp (GRCm38)
  • T to A, chromosome 19 at 6,832,004 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9481 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069284-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.