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Strain Name:
C57BL/6J-MtgxR9484Btlr/Mmmh
Stock Number:
069287-MU
Citation ID:
RRID:MMRRC_069287-MU
Other Names:
R9484 (G1)
Major Collection:

Strain Information

Pofut2
Name: protein O-fucosyltransferase 2
Synonyms: FUT13, 2310011G23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 80294
VEGA: 10
Homologene: 12724
Th
Name: tyrosine hydroxylase
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21823
Homologene: 307
Evl
Name: Ena-vasodilator stimulated phosphoprotein
Synonyms: b2b2600Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14026
VEGA: 12
Homologene: 56752
Lgi1
Name: leucine-rich repeat LGI family, member 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56839
HGNC: HGNC:6572
Homologene: 3737
Smyd1
Name: SET and MYND domain containing 1
Synonyms: Bop, 4632404M21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12180
Homologene: 7645
Lin7c
Name: lin-7 homolog C, crumbs cell polarity complex component
Synonyms: LIN-7-C, LIN-7C, Lin7c, MALS-3, Veli3, D2Ertd520e, 9130007B12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22343
Homologene: 22649
Rps6kb1
Name: ribosomal protein S6 kinase, polypeptide 1
Synonyms: p70/85s6k, p70s6k, S6K1, 2610318I15Rik, p70S6K1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72508
Homologene: 81703
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 74,459,922 bp (GRCm38)
  • A to T, chromosome 1 at 88,406,973 bp (GRCm38)
  • T to C, chromosome 1 at 181,690,208 bp (GRCm38)
  • T to C, chromosome 1 at 181,797,746 bp (GRCm38)
  • CAAA to CAA, chromosome 1 at 189,256,694 bp (GRCm38)
  • G to T, chromosome 1 at 194,644,894 bp (GRCm38)
  • G to A, chromosome 2 at 4,604,215 bp (GRCm38)
  • T to C, chromosome 2 at 5,961,267 bp (GRCm38)
  • T to C, chromosome 2 at 29,735,809 bp (GRCm38)
  • T to A, chromosome 2 at 29,842,748 bp (GRCm38)
  • T to C, chromosome 2 at 31,083,026 bp (GRCm38)
  • T to C, chromosome 2 at 109,894,468 bp (GRCm38)
  • T to A, chromosome 2 at 154,643,843 bp (GRCm38)
  • A to T, chromosome 3 at 28,594,944 bp (GRCm38)
  • T to A, chromosome 3 at 105,965,088 bp (GRCm38)
  • T to C, chromosome 4 at 14,666,012 bp (GRCm38)
  • A to G, chromosome 4 at 33,071,352 bp (GRCm38)
  • T to A, chromosome 4 at 88,522,678 bp (GRCm38)
  • A to T, chromosome 4 at 94,643,336 bp (GRCm38)
  • G to T, chromosome 4 at 117,676,111 bp (GRCm38)
  • T to C, chromosome 4 at 155,695,039 bp (GRCm38)
  • T to A, chromosome 5 at 16,356,833 bp (GRCm38)
  • T to A, chromosome 5 at 52,538,594 bp (GRCm38)
  • C to T, chromosome 5 at 72,339,937 bp (GRCm38)
  • A to T, chromosome 5 at 115,112,786 bp (GRCm38)
  • T to A, chromosome 5 at 124,823,444 bp (GRCm38)
  • A to T, chromosome 5 at 125,783,356 bp (GRCm38)
  • T to C, chromosome 6 at 23,626,647 bp (GRCm38)
  • T to A, chromosome 6 at 29,366,163 bp (GRCm38)
  • T to A, chromosome 6 at 34,934,186 bp (GRCm38)
  • T to A, chromosome 6 at 69,016,782 bp (GRCm38)
  • A to G, chromosome 6 at 71,225,466 bp (GRCm38)
  • C to T, chromosome 6 at 141,908,946 bp (GRCm38)
  • A to T, chromosome 7 at 25,081,979 bp (GRCm38)
  • A to G, chromosome 7 at 43,590,157 bp (GRCm38)
  • C to T, chromosome 7 at 103,843,032 bp (GRCm38)
  • T to C, chromosome 7 at 140,651,991 bp (GRCm38)
  • T to A, chromosome 7 at 142,202,331 bp (GRCm38)
  • C to A, chromosome 7 at 142,899,883 bp (GRCm38)
  • C to T, chromosome 8 at 11,007,334 bp (GRCm38)
  • T to C, chromosome 8 at 119,948,765 bp (GRCm38)
  • T to A, chromosome 9 at 36,843,797 bp (GRCm38)
  • A to T, chromosome 9 at 75,297,488 bp (GRCm38)
  • C to A, chromosome 9 at 107,983,838 bp (GRCm38)
  • C to A, chromosome 9 at 108,812,638 bp (GRCm38)
  • T to C, chromosome 9 at 119,180,549 bp (GRCm38)
  • A to T, chromosome 9 at 121,915,917 bp (GRCm38)
  • A to C, chromosome 10 at 5,220,359 bp (GRCm38)
  • G to A, chromosome 10 at 29,196,973 bp (GRCm38)
  • C to T, chromosome 10 at 41,451,433 bp (GRCm38)
  • T to G, chromosome 10 at 63,167,240 bp (GRCm38)
  • T to C, chromosome 10 at 77,259,426 bp (GRCm38)
  • T to C, chromosome 10 at 80,644,269 bp (GRCm38)
  • T to A, chromosome 10 at 107,822,033 bp (GRCm38)
  • C to T, chromosome 10 at 107,901,295 bp (GRCm38)
  • T to C, chromosome 11 at 49,217,281 bp (GRCm38)
  • T to A, chromosome 11 at 53,988,947 bp (GRCm38)
  • A to C, chromosome 11 at 55,309,926 bp (GRCm38)
  • T to C, chromosome 11 at 61,336,234 bp (GRCm38)
  • A to T, chromosome 11 at 78,403,407 bp (GRCm38)
  • C to T, chromosome 11 at 86,517,617 bp (GRCm38)
  • A to G, chromosome 11 at 100,423,134 bp (GRCm38)
  • A to G, chromosome 12 at 31,461,786 bp (GRCm38)
  • C to A, chromosome 12 at 36,381,712 bp (GRCm38)
  • A to T, chromosome 12 at 83,791,844 bp (GRCm38)
  • A to T, chromosome 12 at 87,895,479 bp (GRCm38)
  • A to T, chromosome 12 at 103,411,296 bp (GRCm38)
  • T to A, chromosome 12 at 108,686,457 bp (GRCm38)
  • T to C, chromosome 12 at 112,046,250 bp (GRCm38)
  • C to A, chromosome 13 at 21,347,417 bp (GRCm38)
  • A to G, chromosome 14 at 7,929,004 bp (GRCm38)
  • T to C, chromosome 14 at 29,986,344 bp (GRCm38)
  • T to C, chromosome 14 at 32,180,629 bp (GRCm38)
  • A to C, chromosome 14 at 121,581,432 bp (GRCm38)
  • A to G, chromosome 15 at 81,636,825 bp (GRCm38)
  • A to G, chromosome 16 at 62,924,524 bp (GRCm38)
  • A to G, chromosome 17 at 33,630,010 bp (GRCm38)
  • T to A, chromosome 17 at 34,241,015 bp (GRCm38)
  • C to A, chromosome 17 at 84,429,191 bp (GRCm38)
  • A to T, chromosome 18 at 36,024,348 bp (GRCm38)
  • T to C, chromosome 19 at 12,268,371 bp (GRCm38)
  • T to C, chromosome 19 at 28,531,003 bp (GRCm38)
  • A to G, chromosome 19 at 38,306,309 bp (GRCm38)
  • A to T, chromosome 19 at 60,766,568 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9484 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069287-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.