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Strain Name:
C57BL/6J-MtgxR9509Btlr/Mmmh
Stock Number:
069312-MU
Citation ID:
RRID:MMRRC_069312-MU
Other Names:
R9509 (G1)
Major Collection:

Strain Information

Dspp
Name: dentin sialophosphoprotein
Synonyms: Dmp3, Dpp, Dsp
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 666279
HGNC: HGNC:3054
Vldlr
Name: very low density lipoprotein receptor
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 22359
Homologene: 443
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216860
Homologene: 13029
Pibf1
Name: progesterone immunomodulatory binding factor 1
Synonyms: 1700017E21Rik, 4933438D16Rik, 4933439E17Rik, 4930513H15Rik, D14Ertd581e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 52023
VEGA: 14
Homologene: 4628
Erp44
Name: endoplasmic reticulum protein 44
Synonyms: 1110001E24Rik, Txndc4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76299
Homologene: 12638
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to T, chromosome 1 at 33,908,384 bp (GRCm38)
  • T to C, chromosome 1 at 34,723,691 bp (GRCm38)
  • A to G, chromosome 1 at 105,686,979 bp (GRCm38)
  • G to A, chromosome 1 at 134,188,675 bp (GRCm38)
  • A to G, chromosome 1 at 156,655,929 bp (GRCm38)
  • T to A, chromosome 1 at 188,916,243 bp (GRCm38)
  • G to A, chromosome 2 at 31,674,743 bp (GRCm38)
  • T to A, chromosome 2 at 44,997,864 bp (GRCm38)
  • A to T, chromosome 2 at 158,127,290 bp (GRCm38)
  • A to G, chromosome 2 at 162,967,383 bp (GRCm38)
  • A to C, chromosome 3 at 95,354,589 bp (GRCm38)
  • TTCCTCCTCCTCCTCCTCCTCC to TTCCTCCTCCTCCTCCTCC, chromosome 3 at 138,065,834 bp (GRCm38)
  • T to A, chromosome 4 at 14,892,485 bp (GRCm38)
  • C to T, chromosome 4 at 44,994,332 bp (GRCm38)
  • T to C, chromosome 4 at 48,208,750 bp (GRCm38)
  • A to G, chromosome 4 at 90,224,706 bp (GRCm38)
  • T to A, chromosome 4 at 98,774,867 bp (GRCm38)
  • A to T, chromosome 5 at 4,046,349 bp (GRCm38)
  • A to T, chromosome 5 at 22,344,200 bp (GRCm38)
  • C to T, chromosome 5 at 34,197,548 bp (GRCm38)
  • G to T, chromosome 5 at 90,773,189 bp (GRCm38)
  • C to A, chromosome 5 at 104,177,791 bp (GRCm38)
  • A to T, chromosome 6 at 84,210,797 bp (GRCm38)
  • A to T, chromosome 6 at 118,084,430 bp (GRCm38)
  • T to A, chromosome 6 at 125,122,522 bp (GRCm38)
  • A to T, chromosome 6 at 125,342,641 bp (GRCm38)
  • C to T, chromosome 7 at 66,708,371 bp (GRCm38)
  • C to T, chromosome 7 at 79,091,020 bp (GRCm38)
  • T to A, chromosome 7 at 85,754,867 bp (GRCm38)
  • CGGCGGCGG to CGGCGGCGGGGGCGGCGG, chromosome 7 at 97,579,920 bp (GRCm38)
  • T to C, chromosome 7 at 104,304,344 bp (GRCm38)
  • T to A, chromosome 7 at 107,823,233 bp (GRCm38)
  • T to A, chromosome 7 at 122,128,176 bp (GRCm38)
  • T to A, chromosome 7 at 122,998,568 bp (GRCm38)
  • T to A, chromosome 7 at 140,299,731 bp (GRCm38)
  • A to T, chromosome 8 at 48,313,257 bp (GRCm38)
  • C to A, chromosome 8 at 69,706,946 bp (GRCm38)
  • C to T, chromosome 9 at 60,872,216 bp (GRCm38)
  • C to T, chromosome 9 at 65,435,865 bp (GRCm38)
  • C to T, chromosome 9 at 95,743,196 bp (GRCm38)
  • A to G, chromosome 9 at 109,148,149 bp (GRCm38)
  • A to T, chromosome 10 at 5,348,927 bp (GRCm38)
  • T to C, chromosome 10 at 5,862,576 bp (GRCm38)
  • T to C, chromosome 10 at 62,429,632 bp (GRCm38)
  • A to T, chromosome 10 at 82,296,395 bp (GRCm38)
  • T to G, chromosome 10 at 84,631,786 bp (GRCm38)
  • T to C, chromosome 10 at 118,146,825 bp (GRCm38)
  • G to A, chromosome 11 at 29,464,143 bp (GRCm38)
  • A to T, chromosome 11 at 32,215,055 bp (GRCm38)
  • A to G, chromosome 11 at 49,494,649 bp (GRCm38)
  • A to G, chromosome 11 at 55,309,887 bp (GRCm38)
  • G to A, chromosome 11 at 58,439,945 bp (GRCm38)
  • T to A, chromosome 11 at 69,902,145 bp (GRCm38)
  • G to A, chromosome 11 at 75,438,069 bp (GRCm38)
  • G to A, chromosome 11 at 77,104,151 bp (GRCm38)
  • A to T, chromosome 11 at 103,863,248 bp (GRCm38)
  • T to C, chromosome 12 at 5,140,629 bp (GRCm38)
  • T to A, chromosome 12 at 17,280,988 bp (GRCm38)
  • A to G, chromosome 12 at 53,142,238 bp (GRCm38)
  • T to A, chromosome 12 at 87,138,028 bp (GRCm38)
  • T to C, chromosome 13 at 32,720,560 bp (GRCm38)
  • T to A, chromosome 13 at 73,494,832 bp (GRCm38)
  • T to A, chromosome 13 at 92,368,231 bp (GRCm38)
  • T to C, chromosome 14 at 31,084,957 bp (GRCm38)
  • T to C, chromosome 14 at 99,101,285 bp (GRCm38)
  • A to G, chromosome 15 at 7,159,474 bp (GRCm38)
  • A to T, chromosome 15 at 35,841,311 bp (GRCm38)
  • C to A, chromosome 15 at 77,488,768 bp (GRCm38)
  • C to A, chromosome 15 at 78,490,216 bp (GRCm38)
  • T to C, chromosome 16 at 3,964,816 bp (GRCm38)
  • T to A, chromosome 16 at 72,962,279 bp (GRCm38)
  • G to A, chromosome 16 at 84,852,507 bp (GRCm38)
  • A to T, chromosome 17 at 6,435,016 bp (GRCm38)
  • C to A, chromosome 17 at 21,434,367 bp (GRCm38)
  • A to G, chromosome 17 at 38,275,390 bp (GRCm38)
  • T to C, chromosome 17 at 73,337,451 bp (GRCm38)
  • A to T, chromosome 18 at 36,535,390 bp (GRCm38)
  • C to G, chromosome 18 at 58,114,478 bp (GRCm38)
  • A to G, chromosome 19 at 25,095,621 bp (GRCm38)
  • A to G, chromosome 19 at 27,244,287 bp (GRCm38)
  • A to T, chromosome 19 at 46,063,399 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9509 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069312-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.