Strain Name:
C57BL/6J-MtgxR9572Btlr/Mmmh
Stock Number:
069365-MU
Citation ID:
RRID:MMRRC_069365-MU
Other Names:
R9572 (G1)
Major Collection:

Strain Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: Spnb4, dyn, 5830426A08Rik, 1700022P15Rik, nmf261, SpbIV, ROSA62, neuroaxonal dystrophy
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80297
Homologene: 11879
Sstr2
Name: somatostatin receptor 2
Synonyms: Smstr2, Smstr-2, SSTR-2, sst2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20606
Homologene: 37427
Dst
Name: dystonin
Synonyms: Macf2, A830042E19Rik, Bpag1, Bpag, bullous pemphigoid antigen 1, nmf203, athetoid, nmf339, BPAG1, BPAG1-n, 2310001O04Rik, bullous pemphigoid antigen 1, ah
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Ano1
Name: anoctamin 1, calcium activated chloride channel
Synonyms: Tmem16a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101772
Homologene: 75079
Ptma
Name: prothymosin alpha
Synonyms: Thym
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19231
HGNC: HGNC:9623
Homologene: 137217
Ppp2r5e
Name: protein phosphatase 2, regulatory subunit B', epsilon
Synonyms: protein phosphatase 2A subunit beta, B56beta, 4633401M22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 26932
VEGA: 12
HGNC: HGNC:9313
Homologene: 55962
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, 2610021O03Rik, Apc1, Mcpr
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17222
Homologene: 7414
Zfp106
Name: zinc finger protein 106
Synonyms: Cd-1, H3a, sirm, Sh3bp3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20402
Homologene: 40787
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: 8030453L17Rik, KMT2H, chromatin remodeling factor, E430018P19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Clock
Name: clock circadian regulator
Synonyms: KAT13D, 5330400M04Rik, bHLHe8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Iws1
Name: IWS1, SUPT6 interacting protein
Synonyms: 1700069O15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 73473
Homologene: 134421
Rab3b
Name: RAB3B, member RAS oncogene family
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69908
HGNC: HGNC:9778
Homologene: 2149
Rpn1
Name: ribophorin I
Synonyms: Rpn-1, D6Wsu137e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 103963
Homologene: 2213
Bccip
Name: BRCA2 and CDKN1A interacting protein
Synonyms: TOK-1, 1110013J05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66165
HGNC: HGNC:978
Homologene: 41629
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: D430002O22Rik, LOC381127, D930044O18Rik, C230079D11Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211961
Homologene: 19371
Siglecf
Name: sialic acid binding Ig-like lectin F
Synonyms: mSiglec-F, Siglec5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233186
Homologene: 50482
Tmub2
Name: transmembrane and ubiquitin-like domain containing 2
Synonyms: 2010008E23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72053
Homologene: 18581
Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Synonyms: Nor1, MINOR, NOR-1, TEC
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18124
HGNC: HGNC:7982
Homologene: 5074
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: Trrp6, mtrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
F7
Name: coagulation factor VII
Synonyms: Cf7, FVII
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14068
HGNC: HGNC:3544
Homologene: 7710
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Lgn1, Birc1e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Nuak1
Name: NUAK family, SNF1-like kinase, 1
Synonyms: B230104P22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77976
Homologene: 8896
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Mrc1
Name: mannose receptor, C type 1
Synonyms: MR, CD206
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17533
HGNC: HGNC:7228
Homologene: 37622
Vmn2r100
Name: vomeronasal 2, receptor 100
Synonyms: EG627537
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627537
Homologene: 129750
Astn2
Name: astrotactin 2
Synonyms: Astnl, 1d8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56079
Homologene: 77850
Aldh6a1
Name: aldehyde dehydrogenase family 6, subfamily A1
Synonyms: Mmsdh, 1110038I05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104776
VEGA: 12
HGNC: HGNC:7179
Homologene: 4082
Nckap5
Name: NCK-associated protein 5
Synonyms: E030049G20Rik, D130011D22Rik, LOC380609
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210356
Homologene: 35542
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: Rp1h, mG145, oxygen-regulated protein 1, Dcdc3, Orp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19888
Homologene: 4564
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235505
Homologene: 25183
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230622
Homologene: 135888
B4gat1
Name: beta-1,4-glucuronyltransferase 1
Synonyms: B3gnt6, BETA3GNT1, 1500032M01Rik, iGNT, B3gnt1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 108902
VEGA: 19
Homologene: 38239
Grb14
Name: growth factor receptor bound protein 14
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50915
HGNC: HGNC:4565
Homologene: 3303
Serpina3i
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3I
Synonyms: alpha-1 antiproteinase, antitrypsin, 2B2, Gm6930
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 628900
HGNC: HGNC:16
Homologene: 115927
Vwa5a
Name: von Willebrand factor A domain containing 5A
Synonyms: Loh11cr2a, BCSC-1, 5830475I06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67776
HGNC: HGNC:6658
Homologene: 18222
Hrnr
Name: hornerin
Synonyms: S100a18, A530063N20Rik, 1110033K19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68723
Homologene: 138092
Kif26b
Name: kinesin family member 26B
Synonyms: N-11 kinesin, D230039L06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269152
Homologene: 18623
Aldoart1
Name: aldolase 1 A, retrogene 1
Synonyms: Aldoa-ps2, Aldo1-ps2, 4921524E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 353204
Homologene: 128442
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330222
Homologene: 27395
Msh5
Name: mutS homolog 5
Synonyms: Mut5, G7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Mcur1
Name: mitochondrial calcium uniporter regulator 1
Synonyms: Ccdc90a, 6230416A05Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76137
VEGA: 13
Homologene: 134447
Spata7
Name: spermatogenesis associated 7
Synonyms: B230306G18Rik, HSD3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104871
Homologene: 10189
Vcpip1
Name: valosin containing protein (p97)/p47 complex interacting protein 1
Synonyms: 5730421J18Rik, 5730538E15Rik, Vcip135
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70675
Homologene: 11814
Acan
Name: aggrecan
Synonyms: b2b183Clo, Agc1, Cspg1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11595
HGNC: HGNC:319
Homologene: 137204
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 4932441F23Rik, 1200008A14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71710
Homologene: 12559
Xkr5
Name: X-linked Kx blood group related 5
Synonyms: 5430438H03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319581
Homologene: 52219
Ttll13
Name: tubulin tyrosine ligase-like family, member 13
Synonyms: 1700111A04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269954
Homologene: 136186
Cfap221
Name: cilia and flagella associated protein 221
Synonyms: Gm101, Pcdp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226356
Homologene: 88578
Tcerg1l
Name: transcription elongation regulator 1-like
Synonyms: 5730476P14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70571
Homologene: 52165
B3gnt7
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
Synonyms: C330001H22Rik, beta-3GnT7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227327
Homologene: 17049
Phactr2
Name: phosphatase and actin regulator 2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215789
Homologene: 8816
Bag4
Name: BCL2-associated athanogene 4
Synonyms: 2410112I15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67384
HGNC: HGNC:940
Homologene: 31270
Or2ag13
Name: olfactory receptor family 2 subfamily AG member 13
Synonyms: Olfr695, GA_x6K02T2PBJ9-9092181-9091234, MOR283-6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258591
Homologene: 133597
Apol9a
Name: apolipoprotein L 9a
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223672
VEGA: 15
Homologene: 77567
Or5b106
Name: olfactory receptor family 5 subfamily B member 106
Synonyms: MOR202-17, Olfr1459, GA_x6K02T2RE5P-3473421-3472498
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258684
HGNC: HGNC:8324
Homologene: 115532
Chpt1
Name: choline phosphotransferase 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 212862
Homologene: 69297
Pomk
Name: protein-O-mannose kinase
Synonyms: 4930444A02Rik, Sgk196
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74653
Homologene: 12580
Or5w1
Name: olfactory receptor family 5 subfamily W member 1
Synonyms: MOR176-1, Olfr1134, GA_x6K02T2Q125-49162076-49161138
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259032
Homologene: 37013
Gsg1l2
Name: GSG1-like 2
Synonyms: Gm12302
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544792
Homologene: 132038
Ctsr
Name: cathepsin R
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56835
VEGA: 13
Homologene: 75127
Or8b49
Name: olfactory receptor family 8 subfamily B member 49
Synonyms: GA_x6K02T2PVTD-32296575-32297513, MOR165-9P, MOR165-10, Olfr913
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258225
VEGA: 9
Homologene: 79398
Taco1
Name: translational activator of mitochondrially encoded cytochrome c oxidase I
Synonyms: Ccdc44, 2310066I18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70207
Homologene: 39079
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 4,348,439 bp (GRCm38)
  • T to C, chromosome 1 at 9,746,545 bp (GRCm38)
  • T to A, chromosome 1 at 34,211,171 bp (GRCm38)
  • T to A, chromosome 1 at 86,305,770 bp (GRCm38)
  • T to A, chromosome 1 at 86,529,975 bp (GRCm38)
  • T to A, chromosome 1 at 119,945,836 bp (GRCm38)
  • T to A, chromosome 1 at 126,027,717 bp (GRCm38)
  • A to T, chromosome 1 at 178,917,477 bp (GRCm38)
  • T to C, chromosome 2 at 14,229,523 bp (GRCm38)
  • A to G, chromosome 2 at 64,933,336 bp (GRCm38)
  • A to G, chromosome 2 at 87,656,570 bp (GRCm38)
  • G to A, chromosome 2 at 120,519,078 bp (GRCm38)
  • G to T, chromosome 2 at 128,664,056 bp (GRCm38)
  • G to A, chromosome 3 at 14,536,088 bp (GRCm38)
  • A to G, chromosome 3 at 89,052,881 bp (GRCm38)
  • A to G, chromosome 3 at 93,332,160 bp (GRCm38)
  • T to A, chromosome 4 at 48,051,258 bp (GRCm38)
  • A to T, chromosome 4 at 65,381,635 bp (GRCm38)
  • T to A, chromosome 4 at 72,852,533 bp (GRCm38)
  • T to C, chromosome 4 at 108,929,528 bp (GRCm38)
  • C to T, chromosome 4 at 113,127,931 bp (GRCm38)
  • T to C, chromosome 5 at 76,229,491 bp (GRCm38)
  • G to A, chromosome 5 at 141,610,029 bp (GRCm38)
  • T to A, chromosome 6 at 88,102,012 bp (GRCm38)
  • A to T, chromosome 7 at 27,366,670 bp (GRCm38)
  • A to G, chromosome 7 at 43,352,634 bp (GRCm38)
  • T to C, chromosome 7 at 79,098,729 bp (GRCm38)
  • A to T, chromosome 7 at 80,258,260 bp (GRCm38)
  • A to G, chromosome 7 at 106,714,339 bp (GRCm38)
  • G to A, chromosome 7 at 133,720,749 bp (GRCm38)
  • C to T, chromosome 7 at 138,280,058 bp (GRCm38)
  • T to A, chromosome 7 at 144,650,556 bp (GRCm38)
  • A to T, chromosome 8 at 13,033,953 bp (GRCm38)
  • A to G, chromosome 8 at 18,934,150 bp (GRCm38)
  • A to T, chromosome 8 at 25,768,275 bp (GRCm38)
  • T to C, chromosome 8 at 25,982,908 bp (GRCm38)
  • T to A, chromosome 9 at 8,656,621 bp (GRCm38)
  • A to T, chromosome 9 at 38,594,331 bp (GRCm38)
  • A to G, chromosome 9 at 38,737,943 bp (GRCm38)
  • T to A, chromosome 9 at 78,660,306 bp (GRCm38)
  • C to T, chromosome 10 at 13,388,817 bp (GRCm38)
  • C to T, chromosome 10 at 39,083,275 bp (GRCm38)
  • C to A, chromosome 10 at 84,392,315 bp (GRCm38)
  • T to C, chromosome 10 at 88,480,944 bp (GRCm38)
  • A to G, chromosome 11 at 67,786,475 bp (GRCm38)
  • T to A, chromosome 11 at 102,285,715 bp (GRCm38)
  • T to A, chromosome 11 at 106,073,112 bp (GRCm38)
  • A to G, chromosome 11 at 113,625,191 bp (GRCm38)
  • A to T, chromosome 12 at 75,515,694 bp (GRCm38)
  • C to A, chromosome 12 at 84,440,243 bp (GRCm38)
  • T to C, chromosome 12 at 98,648,396 bp (GRCm38)
  • C to A, chromosome 12 at 104,268,484 bp (GRCm38)
  • A to G, chromosome 13 at 43,559,957 bp (GRCm38)
  • A to G, chromosome 13 at 61,163,164 bp (GRCm38)
  • T to C, chromosome 13 at 100,223,313 bp (GRCm38)
  • C to T, chromosome 15 at 77,404,604 bp (GRCm38)
  • A to T, chromosome 17 at 19,521,251 bp (GRCm38)
  • T to C, chromosome 17 at 35,031,393 bp (GRCm38)
  • T to A, chromosome 18 at 22,516,055 bp (GRCm38)
  • T to A, chromosome 18 at 32,070,204 bp (GRCm38)
  • T to G, chromosome 19 at 5,039,446 bp (GRCm38)
  • T to A, chromosome 19 at 13,146,564 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9572 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069365-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.