Strain Name:
C57BL/6J-MtgxR9589Btlr/Mmmh
Stock Number:
069382-MU
Citation ID:
RRID:MMRRC_069382-MU
Other Names:
R9589 (G1)
Major Collection:

Strain Information

Kifc3
Name: kinesin family member C3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16582
HGNC: HGNC:6326
Homologene: 124421
Fn1
Name: fibronectin 1
Synonyms: Fn, Fn-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Itga8
Name: integrin alpha 8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241226
HGNC: HGNC:6144
Homologene: 37396
Kif13b
Name: kinesin family member 13B
Synonyms: N-3 kinesin, C130021D12Rik, 5330429L19Rik, GAKIN
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16554
VEGA: 14
Homologene: 9073
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: 2810449H11Rik, D130015N03Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Secisbp2l
Name: SECIS binding protein 2-like
Synonyms: 3110001I20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70354
Homologene: 18923
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 277939
Homologene: 19524
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 386750
Homologene: 8955
Pah
Name: phenylalanine hydroxylase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18478
HGNC: HGNC:8582
Homologene: 234
Gad1
Name: glutamate decarboxylase 1
Synonyms: GAD25, GAD67, Gad-1, Z49976, GAD44, EP10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14415
HGNC: HGNC:4092
Homologene: 635
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, repro4, Mtap2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Rfx7
Name: regulatory factor X, 7
Synonyms: 2510005N23Rik, D130086K05Rik, Rfxdc2, 9930116O05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319758
Homologene: 11275
Ppp4r2
Name: protein phosphatase 4, regulatory subunit 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232314
Homologene: 17953
Plekhh2
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213556
VEGA: 17
Homologene: 35317
Slc6a18
Name: solute carrier family 6 (neurotransmitter transporter), member 18
Synonyms: Xtrp2, XT2, D630001K16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 22598
VEGA: 13
Homologene: 40785
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Fyb2
Name: FYN binding protein 2
Synonyms: 1700024P16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242594
Homologene: 52981
Vmn2r73
Name: vomeronasal 2, receptor 73
Synonyms: EG620928
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620928
Homologene: 115466
Sec11a
Name: SEC11 homolog A, signal peptidase complex subunit
Synonyms: sid2895, Spc18, 1810012E07Rik, 18kDa, Sec11l1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56529
Homologene: 55536
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1a, Mtap-1, Mtap1, 6330416M19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Adgrg3
Name: adhesion G protein-coupled receptor G3
Synonyms: Gpr97, A030001G24Rik, Pb99
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54672
Homologene: 18129
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 4832404P21Rik, 2310021P13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Shpk
Name: sedoheptulokinase
Synonyms: 4930431K22Rik, Carkl
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74637
HGNC: HGNC:1492
Homologene: 8319
Or51a39
Name: olfactory receptor family 51 subfamily A member 39
Synonyms: Olfr33, MTPCR33, MOR11-2, GA_x6K02T2PBJ9-5431102-5430146
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18332
Homologene: 81534
Gcnt1
Name: glucosaminyl (N-acetyl) transferase 1, core 2
Synonyms: C2 GlcNAcT, IGnT, 5630400D21Rik, beta-1, 6-N-acetylglucosaminyltransferase
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14537
HGNC: HGNC:4203
Homologene: 37486
Stmn4
Name: stathmin-like 4
Synonyms: RB3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56471
Homologene: 10496
Tmem237
Name: transmembrane protein 237
Synonyms: LOC381259, Als2cr4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381259
Homologene: 17570
Smg9
Name: SMG9 nonsense mediated mRNA decay factor
Synonyms: smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans), 1500002O20Rik, N28092
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71997
Homologene: 10426
Kcnk15
Name: potassium channel, subfamily K, member 15
Synonyms: KCNK11, TASK5, KCNK14, KT3.3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241769
Homologene: 11179
Lrrc63
Name: leucine rich repeat containing 63
Synonyms: 4921509B22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70859
Homologene: 52823
Htra3
Name: HtrA serine peptidase 3
Synonyms: 9530081K03Rik, 2210021K23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 78558
Homologene: 12697
Zfp28
Name: zinc finger protein 28
Synonyms: mkr-5, Zfp-28, 2810438M17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22690
Homologene: 69047
Ccdc17
Name: coiled-coil domain containing 17
Synonyms: 1100001F07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 622665
Homologene: 77410
Ighv11-2
Name: immunoglobulin heavy variable V11-2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780818
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 59,119,987 bp (GRCm38)
  • A to G, chromosome 1 at 66,410,594 bp (GRCm38)
  • A to T, chromosome 1 at 71,629,782 bp (GRCm38)
  • C to T, chromosome 2 at 12,232,890 bp (GRCm38)
  • T to C, chromosome 2 at 70,585,940 bp (GRCm38)
  • T to C, chromosome 2 at 121,305,917 bp (GRCm38)
  • C to A, chromosome 2 at 125,747,505 bp (GRCm38)
  • T to G, chromosome 2 at 125,747,510 bp (GRCm38)
  • C to T, chromosome 2 at 163,858,207 bp (GRCm38)
  • T to C, chromosome 3 at 73,050,648 bp (GRCm38)
  • C to A, chromosome 4 at 105,015,636 bp (GRCm38)
  • A to G, chromosome 4 at 116,597,594 bp (GRCm38)
  • T to C, chromosome 5 at 35,664,065 bp (GRCm38)
  • A to T, chromosome 6 at 40,750,585 bp (GRCm38)
  • C to T, chromosome 6 at 100,861,448 bp (GRCm38)
  • T to A, chromosome 7 at 6,389,817 bp (GRCm38)
  • T to G, chromosome 7 at 24,420,821 bp (GRCm38)
  • T to C, chromosome 7 at 80,916,151 bp (GRCm38)
  • A to G, chromosome 7 at 85,870,451 bp (GRCm38)
  • T to A, chromosome 7 at 100,432,549 bp (GRCm38)
  • T to C, chromosome 7 at 102,714,165 bp (GRCm38)
  • A to G, chromosome 8 at 95,033,465 bp (GRCm38)
  • A to T, chromosome 8 at 95,134,744 bp (GRCm38)
  • T to A, chromosome 9 at 66,465,558 bp (GRCm38)
  • T to C, chromosome 9 at 72,617,840 bp (GRCm38)
  • T to A, chromosome 10 at 87,567,335 bp (GRCm38)
  • C to T, chromosome 11 at 73,213,441 bp (GRCm38)
  • G to T, chromosome 12 at 112,782,728 bp (GRCm38)
  • A to T, chromosome 12 at 114,048,427 bp (GRCm38)
  • G to T, chromosome 13 at 46,802,544 bp (GRCm38)
  • A to G, chromosome 13 at 73,668,204 bp (GRCm38)
  • A to G, chromosome 14 at 20,713,103 bp (GRCm38)
  • T to C, chromosome 14 at 64,776,310 bp (GRCm38)
  • A to G, chromosome 14 at 66,357,889 bp (GRCm38)
  • A to T, chromosome 14 at 75,084,939 bp (GRCm38)
  • G to A, chromosome 17 at 84,547,490 bp (GRCm38)
  • G to A, chromosome 19 at 17,330,058 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9589 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069382-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.