Strain Name:
C57BL/6J-MtgxR9601Btlr/Mmmh
Stock Number:
069394-MU
Citation ID:
RRID:MMRRC_069394-MU
Other Names:
R9601 (G1)
Major Collection:

Strain Information

Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20349
Homologene: 8247
Pofut2
Name: protein O-fucosyltransferase 2
Synonyms: FUT13, 2310011G23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 80294
VEGA: 10
Homologene: 12724
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 0610038M01Rik, 2610510B01Rik, Dopey2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: Bat2l, 5830434P21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227723
Homologene: 106649
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: b2b1625.2Clo, Gp330, Megalin, D230004K18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Sfswap
Name: splicing factor SWAP
Synonyms: 1190005N23Rik, Sfrs8, 6330437E22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231769
Homologene: 134548
Plxna1
Name: plexin A1
Synonyms: 2600013D04Rik, NOV, PlexA1, Plxn1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18844
HGNC: HGNC:9099
Homologene: 56426
Bop1
Name: block of proliferation 1
Synonyms: Erb1p
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12181
VEGA: 15
Homologene: 6612
Hmmr
Name: hyaluronan mediated motility receptor (RHAMM)
Synonyms: Rhamm, CD168
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15366
HGNC: HGNC:5012
Homologene: 8271
Clptm1
Name: cleft lip and palate associated transmembrane protein 1
Synonyms: HS9, N14
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56457
HGNC: HGNC:2087
Homologene: 37464
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109151
Homologene: 11844
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Ufl1
Name: UFM1 specific ligase 1
Synonyms: Maxer, 1810074P20Rik, Rcad
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67490
Homologene: 9093
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE-1, A330049M09Rik, enaptin165, nesprin-1, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: CAMDI, 2610301F02Rik, ENSMUSG00000075261
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545428
Homologene: 52149
Zfp992
Name: zinc finger protein 992
Synonyms: Gm13251
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433791
Homologene: 133076
Dbx1
Name: developing brain homeobox 1
Synonyms: Mmox C, Dbx
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13172
Homologene: 19002
Cux2
Name: cut-like homeobox 2
Synonyms: Cutl2, ENSMUSG00000072641, Cux-2, Cux2, 1700051K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13048
Homologene: 22426
Ccdc187
Name: coiled-coil domain containing 187
Synonyms: 4932418E24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329366
Homologene: 77630
Sptb
Name: spectrin beta, erythrocytic
Synonyms: LOC383567, brain erythroid spectrin (235E), spectrin R, D330027P03Rik, Spnb-1, Spnb1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20741
Homologene: 295
Cdc20
Name: cell division cycle 20
Synonyms: 2310042N09Rik, p55CDC
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107995
HGNC: HGNC:1723
Homologene: 37459
Katnip
Name: katanin interacting protein
Synonyms: D430042O09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233865
Homologene: 45841
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: D2Ertd794e, 5830435C13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930543C13Rik, 4930516E05Rik, D330038K10Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Fgd2
Name: FYVE, RhoGEF and PH domain containing 2
Synonyms: Tcd2, Tcd-2, tcs2, tcs-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26382
HGNC: HGNC:3664
Homologene: 8438
Dsg3
Name: desmoglein 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13512
VEGA: 18
HGNC: HGNC:3050
Homologene: 55513
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Nkpd1
Name: NTPase, KAP family P-loop domain containing 1
Synonyms: 2310015G09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69547
Homologene: 18876
Cyp2c66
Name: cytochrome P450, family 2, subfamily c, polypeptide 66
Synonyms: 2010301M18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69888
Homologene: 133566
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Slc22a21
Name: solute carrier family 22 (organic cation transporter), member 21
Synonyms: Slc22a9, Octn3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56517
Homologene: 137336
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4A, Birc1f, Naip-rs4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: LOC235639, C030048J01Rik, Lba1, A230061D21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320429
Homologene: 45845
Or52z13
Name: olfactory receptor family 52 subfamily Z member 13
Synonyms: Olfr618, MOR31-9, GA_x6K02T2PBJ9-6320148-6321104
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259049
Homologene: 72966
Atp6v0a2
Name: ATPase, H+ transporting, lysosomal V0 subunit A2
Synonyms: 8430408C20Rik, TJ6s, V-ATPase a2, Atp6n2, ATP6a2, Tj6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21871
Homologene: 56523
Klhl25
Name: kelch-like 25
Synonyms: 2810402K13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207952
Homologene: 32546
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12722
HGNC: HGNC:2017
Homologene: 77224
Ccdc157
Name: coiled-coil domain containing 157
Synonyms: 4930562D19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216516
Homologene: 72271
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 636808
Homologene: 43974
Cyp4a29
Name: cytochrome P450, family 4, subfamily a, polypeptide 29
Synonyms: Cyp4a29-ps
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230639
Ahcyl
Name: adenosylhomocysteinase like
Synonyms: Gm4737
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11615
VEGA: 16
HGNC: HGNC:343
Arhgap22
Name: Rho GTPase activating protein 22
Synonyms: B230341L19Rik, RHOGAP2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239027
Homologene: 23292
Mrgprh
Name: MAS-related GPR, member H
Synonyms: MrgH, Gpr90
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 80978
VEGA: 17
Homologene: 12758
Camp
Name: cathelicidin antimicrobial peptide
Synonyms: MCLP, FALL39, Cramp, CAP18, Cnlp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12796
HGNC: HGNC:1472
Homologene: 110678
Slc6a17
Name: solute carrier family 6 (neurotransmitter transporter), member 17
Synonyms: D130012J15Rik, NTT4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229706
Homologene: 27775
Pcdhb21
Name: protocadherin beta 21
Synonyms: Pcdhb18, PcdhbU
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93892
Homologene: 134302
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627367
Homologene: 115024
Grid1
Name: glutamate receptor, ionotropic, delta 1
Synonyms: GluRdelta1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14803
HGNC: HGNC:4575
Homologene: 69017
Gabra1
Name: gamma-aminobutyric acid type A receptor subunit alpha 1
Synonyms: GABAAR alpha1, Gabra-1, GABAA alpha 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14394
HGNC: HGNC:4075
Homologene: 629
Krtcap2
Name: keratinocyte associated protein 2
Synonyms: 0610010I12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66059
Homologene: 15494
Ttll1
Name: tubulin tyrosine ligase-like 1
Synonyms: 6330444E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 319953
HGNC: HGNC:1312
Homologene: 8174
Cpm
Name: carboxypeptidase M
Synonyms: 5730456K23Rik, 1110060I01Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70574
HGNC: HGNC:2311
Homologene: 35367
H2bc12
Name: H2B clustered histone 12
Synonyms: Hist1h2bk
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319184
Homologene: 135980
Vmn1r159
Name: vomeronasal 1 receptor 159
Synonyms: Gm16507
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670857
Homologene: 104166
C8g
Name: complement component 8, gamma polypeptide
Synonyms: 1700013L23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69379
HGNC: HGNC:1354
Homologene: 505
Lipi
Name: lipase, member I
Synonyms: lpd1, D930038D03Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320355
Homologene: 77864
Abhd6
Name: abhydrolase domain containing 6
Synonyms: 0610041D24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66082
VEGA: 14
Homologene: 23246
Spryd7
Name: SPRY domain containing 7
Synonyms: 6330409N04Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66674
Homologene: 10725
Spata21
Name: spermatogenesis associated 21
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329972
Homologene: 18639
Ctsd
Name: cathepsin D
Synonyms: CatD, CD
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13033
HGNC: HGNC:2529
Homologene: 55616
Or4c99
Name: olfactory receptor family 4 subfamily C member 99
Synonyms: GA_x6K02T2Q125-49986553-49987462, MOR230-11, MOR230-10P, Olfr1185
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258059
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 116,580,487 bp (GRCm38)
  • C to T, chromosome 2 at 25,498,904 bp (GRCm38)
  • C to T, chromosome 2 at 26,253,433 bp (GRCm38)
  • C to A, chromosome 2 at 32,200,941 bp (GRCm38)
  • T to C, chromosome 2 at 59,901,503 bp (GRCm38)
  • C to A, chromosome 2 at 69,459,584 bp (GRCm38)
  • T to C, chromosome 2 at 77,054,729 bp (GRCm38)
  • T to A, chromosome 2 at 88,499,970 bp (GRCm38)
  • T to C, chromosome 3 at 89,249,142 bp (GRCm38)
  • T to C, chromosome 3 at 107,473,614 bp (GRCm38)
  • C to T, chromosome 3 at 144,747,549 bp (GRCm38)
  • G to A, chromosome 4 at 25,275,807 bp (GRCm38)
  • T to C, chromosome 4 at 115,248,575 bp (GRCm38)
  • C to T, chromosome 4 at 118,433,519 bp (GRCm38)
  • C to T, chromosome 4 at 141,095,156 bp (GRCm38)
  • C to T, chromosome 4 at 146,467,519 bp (GRCm38)
  • T to A, chromosome 5 at 14,252,383 bp (GRCm38)
  • A to G, chromosome 5 at 121,887,398 bp (GRCm38)
  • G to A, chromosome 5 at 124,713,193 bp (GRCm38)
  • G to A, chromosome 5 at 129,541,399 bp (GRCm38)
  • C to T, chromosome 6 at 89,331,271 bp (GRCm38)
  • A to T, chromosome 7 at 19,523,537 bp (GRCm38)
  • C to A, chromosome 7 at 19,635,838 bp (GRCm38)
  • A to G, chromosome 7 at 22,843,191 bp (GRCm38)
  • G to A, chromosome 7 at 28,154,380 bp (GRCm38)
  • A to T, chromosome 7 at 49,632,655 bp (GRCm38)
  • A to G, chromosome 7 at 75,866,009 bp (GRCm38)
  • A to T, chromosome 7 at 103,597,391 bp (GRCm38)
  • A to G, chromosome 7 at 125,842,920 bp (GRCm38)
  • C to A, chromosome 7 at 142,382,636 bp (GRCm38)
  • A to T, chromosome 8 at 91,005,732 bp (GRCm38)
  • A to T, chromosome 8 at 95,756,207 bp (GRCm38)
  • T to G, chromosome 9 at 79,617,752 bp (GRCm38)
  • T to G, chromosome 9 at 109,848,436 bp (GRCm38)
  • A to G, chromosome 9 at 111,373,125 bp (GRCm38)
  • C to T, chromosome 10 at 5,259,270 bp (GRCm38)
  • T to C, chromosome 10 at 77,259,386 bp (GRCm38)
  • T to C, chromosome 10 at 117,676,094 bp (GRCm38)
  • A to T, chromosome 11 at 4,144,598 bp (GRCm38)
  • A to T, chromosome 11 at 40,707,383 bp (GRCm38)
  • A to T, chromosome 11 at 42,135,574 bp (GRCm38)
  • A to T, chromosome 11 at 53,959,225 bp (GRCm38)
  • G to T, chromosome 12 at 76,620,989 bp (GRCm38)
  • T to C, chromosome 13 at 22,036,223 bp (GRCm38)
  • T to C, chromosome 13 at 100,300,453 bp (GRCm38)
  • T to C, chromosome 14 at 8,049,808 bp (GRCm38)
  • C to A, chromosome 14 at 33,298,770 bp (GRCm38)
  • A to G, chromosome 14 at 35,445,857 bp (GRCm38)
  • T to G, chromosome 14 at 61,545,779 bp (GRCm38)
  • T to A, chromosome 15 at 76,454,488 bp (GRCm38)
  • T to C, chromosome 15 at 83,496,315 bp (GRCm38)
  • A to G, chromosome 16 at 46,154,672 bp (GRCm38)
  • T to A, chromosome 16 at 75,555,818 bp (GRCm38)
  • A to G, chromosome 16 at 93,747,643 bp (GRCm38)
  • T to C, chromosome 17 at 12,877,377 bp (GRCm38)
  • A to G, chromosome 17 at 18,914,508 bp (GRCm38)
  • G to A, chromosome 17 at 29,374,886 bp (GRCm38)
  • T to A, chromosome 18 at 20,533,521 bp (GRCm38)
  • A to T, chromosome 18 at 37,515,332 bp (GRCm38)
  • T to C, chromosome 19 at 16,645,973 bp (GRCm38)
  • A to T, chromosome 19 at 39,186,610 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9601 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069394-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.