Strain Name:
C57BL/6J-MtgxR9603Btlr/Mmmh
Stock Number:
069396-MU
Citation ID:
RRID:MMRRC_069396-MU
Other Names:
R9603 (G1)
Major Collection:

Strain Information

Btrc
Name: beta-transducin repeat containing protein
Synonyms: SCF b-TRCP, beta-TrCP, Slimb, Beta-Trcp1, Fbw1a
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12234
VEGA: 19
HGNC: HGNC:1144
Homologene: 39330
Cdkn2d
Name: cyclin dependent kinase inhibitor 2D
Synonyms: p19, INK4d, p19INK4d, INK4d
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12581
VEGA: 9
HGNC: HGNC:1790
Homologene: 36081
Rai14
Name: retinoic acid induced 14
Synonyms: 1700020L11Rik, Ankycorbin, Norpeg, 1700008J19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75646
VEGA: 15
Homologene: 9199
Pkm
Name: pyruvate kinase, muscle
Synonyms: Pk-3, Pk-2, Pk3, Pkm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18746
VEGA: 9
HGNC: HGNC:9021
Homologene: 37650
Scaf8
Name: SR-related CTD-associated factor 8
Synonyms: A930036P18Rik, A630086M08Rik, Rbm16
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106583
VEGA: 17
Homologene: 8928
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64898
Homologene: 8769
Fzd10
Name: frizzled class receptor 10
Synonyms: Fz-10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 93897
HGNC: HGNC:4039
Homologene: 21411
St6galnac3
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Synonyms: ST6GalNAc III, Siat7c
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20447
Homologene: 7938
Kank1
Name: KN motif and ankyrin repeat domains 1
Synonyms: D330024H06Rik, A930031B09Rik, Ankrd15
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107351
Homologene: 17706
Slitrk3
Name: SLIT and NTRK-like family, member 3
Synonyms: ST3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 386750
Homologene: 8955
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Krr1
Name: KRR1, small subunit (SSU) processome component, homolog (yeast)
Synonyms: 2610511F02Rik, D10Ertd773e, Hrb2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52705
HGNC: HGNC:5176
Homologene: 5114
Cars1
Name: cysteinyl-tRNA synthetase 1
Synonyms: CA3, Cars
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27267
HGNC: HGNC:1493
Homologene: 1328
Tubgcp2
Name: tubulin, gamma complex component 2
Synonyms: 1700022B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74237
Homologene: 55980
Slc25a20
Name: solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
Synonyms: mCAC, Cact, 1110007P09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57279
HGNC: HGNC:1421
Homologene: 331
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: MD44, MTSG1, Atip1, B430305I03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102103
Homologene: 100292
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: 4930548D04Rik, MPP-9, MPP9, B930097C17Rik, 9630025B04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Ebf1
Name: early B cell factor 1
Synonyms: Olf-1, O/E-1, Olf1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Cubn
Name: cubilin
Synonyms: D2Wsu88e, intrinsic factor-cobalamin receptor
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Fstl5
Name: follistatin-like 5
Synonyms: 9130207J01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213262
Homologene: 10584
Zbtb41
Name: zinc finger and BTB domain containing 41
Synonyms: 8430415N23Rik, 9830132G07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226470
Homologene: 27795
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Sntg1
Name: syntrophin, gamma 1
Synonyms: G1SYN, SYN4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71096
Homologene: 56834
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232156
Homologene: 31125
Or6b6
Name: olfactory receptor family 6 subfamily B member 6
Synonyms: GA_x6K02T2PBJ9-9352783-9351839, MOR103-4, Olfr711
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259037
Homologene: 128111
St18
Name: suppression of tumorigenicity 18
Synonyms: Nzf3, Myt3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240690
Homologene: 8792
Hsf4
Name: heat shock transcription factor 4
Synonyms: ldis1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26386
HGNC: HGNC:5227
Homologene: 100128
Foxs1
Name: forkhead box S1
Synonyms: FREAC10, Fkh3, Fkhl18
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14239
HGNC: HGNC:3735
Homologene: 20871
Pramel27
Name: PRAME like 27
Synonyms: Gm13103
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 194225
Homologene: 129883
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: EG668547, Vmn2r119, EG383258
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383258
Homologene: 129687
Pla2g12a
Name: phospholipase A2, group XIIA
Synonyms: 2310004B05Rik, mGXII-1, Pla2g12, GXII, Rossy
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66350
Homologene: 11328
Slamf1
Name: signaling lymphocytic activation molecule family member 1
Synonyms: IPO-3, CD150, ESTM51, CDw150, Slam
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27218
Homologene: 48162
Rnf150
Name: ring finger protein 150
Synonyms: Greul5, A630007N06Rik, C030044C12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330812
Homologene: 33783
Acsl6
Name: acyl-CoA synthetase long-chain family member 6
Synonyms: Lacsl, A330035H04Rik, Facl6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216739
Homologene: 100939
Or2f1b
Name: olfactory receptor family 2 subfamily F member 1B
Synonyms: 18A, MOR257-2, GA_x6K02T2P3E9-4797841-4796888, Olfr38
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258988
HGNC: HGNC:8246
Homologene: 72050
Or4f14
Name: olfactory receptor family 4 subfamily F member 14
Synonyms: GA_x6K02T2Q125-72954873-72953935, MOR245-15, Olfr1306
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258023
Homologene: 128383
Klhl22
Name: kelch-like 22
Synonyms: 2610318I18Rik, Kelchl
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224023
Homologene: 23784
Or13a25
Name: olfactory receptor family 13 subfamily A member 25
Synonyms: GA_x6K02T2PBJ9-42813436-42814368, MOR253-4, Olfr539
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258963
Homologene: 79393
Cavin4
Name: caveolae associated 4
Synonyms: 2310039E09Rik, cavin 4, Murc
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68016
Homologene: 12224
Hrh3
Name: histamine receptor H3
Synonyms: Eae8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99296
HGNC: HGNC:5184
Homologene: 5232
Eif1ad7
Name: eukaryotic translation initiation factor 1A domain containing 7
Synonyms: Gm5662
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 435337
Homologene: 103865
Slc14a1
Name: solute carrier family 14 (urea transporter), member 1
Synonyms: 2610507K20Rik, UT-B, 3021401A05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108052
Homologene: 9285
Rrp1
Name: ribosomal RNA processing 1
Synonyms: NNP-1, Nnp1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18114
VEGA: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 6,845,587 bp (GRCm38)
  • A to T, chromosome 1 at 8,677,974 bp (GRCm38)
  • A to T, chromosome 1 at 139,447,517 bp (GRCm38)
  • G to T, chromosome 1 at 171,798,203 bp (GRCm38)
  • A to T, chromosome 2 at 13,287,699 bp (GRCm38)
  • A to T, chromosome 2 at 13,574,337 bp (GRCm38)
  • A to G, chromosome 2 at 111,912,783 bp (GRCm38)
  • A to C, chromosome 2 at 152,932,361 bp (GRCm38)
  • A to G, chromosome 2 at 157,561,781 bp (GRCm38)
  • C to A, chromosome 2 at 180,100,651 bp (GRCm38)
  • T to C, chromosome 3 at 37,227,800 bp (GRCm38)
  • A to G, chromosome 3 at 73,051,316 bp (GRCm38)
  • C to T, chromosome 3 at 76,588,953 bp (GRCm38)
  • G to A, chromosome 3 at 129,881,251 bp (GRCm38)
  • T to A, chromosome 3 at 153,411,540 bp (GRCm38)
  • T to C, chromosome 4 at 48,671,999 bp (GRCm38)
  • A to T, chromosome 4 at 108,642,091 bp (GRCm38)
  • T to C, chromosome 4 at 143,851,697 bp (GRCm38)
  • C to A, chromosome 5 at 111,418,527 bp (GRCm38)
  • A to T, chromosome 5 at 124,324,952 bp (GRCm38)
  • G to A, chromosome 5 at 128,601,707 bp (GRCm38)
  • C to T, chromosome 6 at 42,762,738 bp (GRCm38)
  • T to G, chromosome 6 at 83,240,732 bp (GRCm38)
  • A to G, chromosome 7 at 28,103,138 bp (GRCm38)
  • A to T, chromosome 7 at 106,971,896 bp (GRCm38)
  • T to C, chromosome 7 at 131,228,914 bp (GRCm38)
  • T to A, chromosome 7 at 140,004,876 bp (GRCm38)
  • G to T, chromosome 7 at 140,667,881 bp (GRCm38)
  • A to G, chromosome 7 at 143,559,192 bp (GRCm38)
  • T to A, chromosome 8 at 24,628,131 bp (GRCm38)
  • A to T, chromosome 8 at 41,083,758 bp (GRCm38)
  • T to A, chromosome 8 at 82,990,579 bp (GRCm38)
  • G to A, chromosome 8 at 105,272,803 bp (GRCm38)
  • T to C, chromosome 9 at 21,290,843 bp (GRCm38)
  • T to A, chromosome 9 at 59,670,548 bp (GRCm38)
  • T to C, chromosome 9 at 108,672,476 bp (GRCm38)
  • A to G, chromosome 10 at 78,404,923 bp (GRCm38)
  • T to C, chromosome 10 at 111,976,767 bp (GRCm38)
  • A to G, chromosome 11 at 44,618,179 bp (GRCm38)
  • A to T, chromosome 11 at 54,335,085 bp (GRCm38)
  • T to G, chromosome 12 at 88,271,957 bp (GRCm38)
  • G to A, chromosome 15 at 10,595,030 bp (GRCm38)
  • A to G, chromosome 16 at 17,777,051 bp (GRCm38)
  • A to G, chromosome 16 at 32,794,785 bp (GRCm38)
  • T to A, chromosome 17 at 3,195,795 bp (GRCm38)
  • C to A, chromosome 17 at 55,592,837 bp (GRCm38)
  • A to G, chromosome 17 at 71,243,415 bp (GRCm38)
  • C to A, chromosome 18 at 78,109,592 bp (GRCm38)
  • A to G, chromosome 19 at 25,430,925 bp (GRCm38)
  • G to A, chromosome 19 at 45,471,087 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9603 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069396-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.