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Strain Name:
C57BL/6J-MtgxR9605Btlr/Mmmh
Stock Number:
069398-MU
Citation ID:
RRID:MMRRC_069398-MU
Other Names:
R9605 (G1)
Major Collection:

Strain Information

Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Adipor1
Name: adiponectin receptor 1
Synonyms: 2810031L11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72674
Homologene: 69199
Rab6b
Name: RAB6B, member RAS oncogene family
Synonyms: C330006L04Rik, D9Bwg0185e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270192
Homologene: 39749
Dock1
Name: dedicator of cytokinesis 1
Synonyms: D630004B07Rik, 9130006G06Rik, Dock180, b2b3190Clo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330662
HGNC: HGNC:2987
Homologene: 55575
Pepd
Name: peptidase D
Synonyms: Pep-4, peptidase D, Pep4, dal
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18624
HGNC: HGNC:8840
Homologene: 239
Sik3
Name: SIK family kinase 3
Synonyms: 5730525O22Rik, 9030204A07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70661
Homologene: 57023
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 34,722,664 bp (GRCm38)
  • A to T, chromosome 1 at 36,234,805 bp (GRCm38)
  • A to T, chromosome 1 at 65,264,402 bp (GRCm38)
  • T to G, chromosome 1 at 74,747,219 bp (GRCm38)
  • A to G, chromosome 1 at 79,435,219 bp (GRCm38)
  • A to G, chromosome 1 at 134,424,815 bp (GRCm38)
  • A to T, chromosome 1 at 136,416,856 bp (GRCm38)
  • A to T, chromosome 1 at 154,204,364 bp (GRCm38)
  • A to G, chromosome 1 at 174,208,314 bp (GRCm38)
  • C to T, chromosome 1 at 174,608,628 bp (GRCm38)
  • A to G, chromosome 2 at 14,319,299 bp (GRCm38)
  • A to T, chromosome 2 at 20,766,534 bp (GRCm38)
  • T to G, chromosome 2 at 87,833,134 bp (GRCm38)
  • G to T, chromosome 2 at 101,694,280 bp (GRCm38)
  • A to G, chromosome 2 at 104,256,844 bp (GRCm38)
  • A to T, chromosome 2 at 112,661,621 bp (GRCm38)
  • G to A, chromosome 2 at 127,245,764 bp (GRCm38)
  • C to T, chromosome 3 at 37,451,781 bp (GRCm38)
  • C to A, chromosome 3 at 54,318,129 bp (GRCm38)
  • T to A, chromosome 3 at 88,762,018 bp (GRCm38)
  • G to T, chromosome 4 at 15,998,427 bp (GRCm38)
  • A to T, chromosome 4 at 19,505,187 bp (GRCm38)
  • A to T, chromosome 4 at 59,914,056 bp (GRCm38)
  • G to T, chromosome 4 at 103,353,529 bp (GRCm38)
  • T to C, chromosome 4 at 124,936,591 bp (GRCm38)
  • T to A, chromosome 4 at 139,085,297 bp (GRCm38)
  • G to A, chromosome 5 at 64,286,007 bp (GRCm38)
  • T to C, chromosome 5 at 65,806,536 bp (GRCm38)
  • C to T, chromosome 5 at 134,504,762 bp (GRCm38)
  • A to G, chromosome 5 at 135,852,251 bp (GRCm38)
  • A to T, chromosome 5 at 140,469,706 bp (GRCm38)
  • A to G, chromosome 6 at 140,648,010 bp (GRCm38)
  • T to C, chromosome 6 at 148,842,834 bp (GRCm38)
  • A to T, chromosome 7 at 3,310,844 bp (GRCm38)
  • G to A, chromosome 7 at 3,717,618 bp (GRCm38)
  • G to A, chromosome 7 at 17,759,595 bp (GRCm38)
  • A to G, chromosome 7 at 19,507,532 bp (GRCm38)
  • A to G, chromosome 7 at 29,776,839 bp (GRCm38)
  • A to C, chromosome 7 at 35,043,793 bp (GRCm38)
  • C to T, chromosome 7 at 62,348,589 bp (GRCm38)
  • T to C, chromosome 7 at 102,097,205 bp (GRCm38)
  • T to C, chromosome 7 at 120,891,947 bp (GRCm38)
  • T to A, chromosome 7 at 126,410,885 bp (GRCm38)
  • T to A, chromosome 7 at 134,782,412 bp (GRCm38)
  • C to T, chromosome 8 at 75,117,540 bp (GRCm38)
  • G to A, chromosome 8 at 120,145,641 bp (GRCm38)
  • A to G, chromosome 9 at 20,170,797 bp (GRCm38)
  • A to G, chromosome 9 at 21,735,330 bp (GRCm38)
  • A to G, chromosome 9 at 44,681,119 bp (GRCm38)
  • T to A, chromosome 9 at 46,208,819 bp (GRCm38)
  • A to T, chromosome 9 at 103,140,402 bp (GRCm38)
  • G to A, chromosome 9 at 110,517,642 bp (GRCm38)
  • A to T, chromosome 9 at 120,018,208 bp (GRCm38)
  • T to A, chromosome 10 at 39,645,776 bp (GRCm38)
  • A to G, chromosome 10 at 111,996,896 bp (GRCm38)
  • A to G, chromosome 11 at 45,984,813 bp (GRCm38)
  • G to T, chromosome 11 at 54,490,887 bp (GRCm38)
  • C to T, chromosome 11 at 74,667,946 bp (GRCm38)
  • T to A, chromosome 11 at 75,669,073 bp (GRCm38)
  • C to T, chromosome 11 at 84,293,016 bp (GRCm38)
  • T to C, chromosome 11 at 98,420,920 bp (GRCm38)
  • T to A, chromosome 11 at 100,808,450 bp (GRCm38)
  • A to G, chromosome 11 at 119,469,053 bp (GRCm38)
  • T to C, chromosome 11 at 120,011,383 bp (GRCm38)
  • A to G, chromosome 12 at 104,319,834 bp (GRCm38)
  • T to C, chromosome 12 at 117,161,658 bp (GRCm38)
  • T to A, chromosome 13 at 33,972,378 bp (GRCm38)
  • A to C, chromosome 13 at 62,871,209 bp (GRCm38)
  • T to C, chromosome 13 at 113,319,969 bp (GRCm38)
  • A to T, chromosome 14 at 45,205,342 bp (GRCm38)
  • A to T, chromosome 14 at 52,219,598 bp (GRCm38)
  • A to C, chromosome 14 at 103,664,676 bp (GRCm38)
  • G to A, chromosome 15 at 3,333,511 bp (GRCm38)
  • A to T, chromosome 15 at 76,181,013 bp (GRCm38)
  • T to A, chromosome 15 at 82,790,471 bp (GRCm38)
  • A to T, chromosome 15 at 91,737,217 bp (GRCm38)
  • G to T, chromosome 15 at 101,438,603 bp (GRCm38)
  • A to G, chromosome 16 at 13,677,223 bp (GRCm38)
  • A to T, chromosome 16 at 26,363,174 bp (GRCm38)
  • A to G, chromosome 16 at 37,022,811 bp (GRCm38)
  • A to T, chromosome 16 at 77,077,158 bp (GRCm38)
  • G to T, chromosome 16 at 95,715,077 bp (GRCm38)
  • A to G, chromosome 17 at 6,013,519 bp (GRCm38)
  • A to G, chromosome 17 at 21,464,029 bp (GRCm38)
  • T to A, chromosome 17 at 34,862,982 bp (GRCm38)
  • T to A, chromosome 17 at 37,499,440 bp (GRCm38)
  • A to T, chromosome 17 at 46,473,590 bp (GRCm38)
  • A to G, chromosome 17 at 57,411,083 bp (GRCm38)
  • T to A, chromosome 18 at 23,631,397 bp (GRCm38)
  • A to G, chromosome 18 at 74,799,159 bp (GRCm38)
  • C to A, chromosome 18 at 78,109,592 bp (GRCm38)
  • A to G, chromosome 19 at 5,337,757 bp (GRCm38)
  • A to T, chromosome 19 at 10,255,689 bp (GRCm38)
  • A to T, chromosome 19 at 39,777,999 bp (GRCm38)
  • A to T, chromosome 19 at 48,722,925 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9605 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069398-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.