Strain Name:
C57BL/6J-MtgxR9615Btlr/Mmmh
Stock Number:
069408-MU
Citation ID:
RRID:MMRRC_069408-MU
Other Names:
R9615 (G1)
Major Collection:

Strain Information

Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223666
Homologene: 27825
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Dgkh
Name: diacylglycerol kinase, eta
Synonyms: 5930402B05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380921
VEGA: 14
HGNC: HGNC:2854
Homologene: 99373
Hdlbp
Name: high density lipoprotein (HDL) binding protein
Synonyms: 1110005P14Rik, D1Ertd101e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 110611
HGNC: HGNC:4857
Homologene: 38035
Samd4b
Name: sterile alpha motif domain containing 4B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233033
Homologene: 35268
Vps35
Name: VPS35 retromer complex component
Synonyms: Mem3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 65114
Homologene: 6221
Nbr1
Name: NBR1, autophagy cargo receptor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17966
HGNC: HGNC:6746
Homologene: 7438
Prom1
Name: prominin 1
Synonyms: AC133, Prom-1, CD133, 4932416E19Rik, Prom
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Cramp1
Name: cramped chromatin regulator 1
Synonyms: Cramp1l, 5830477H08Rik, Tce4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57354
VEGA: 17
Homologene: 35373
Smndc1
Name: survival motor neuron domain containing 1
Synonyms: 2410004J23Rik, 4933440I19Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76479
VEGA: 19
Homologene: 4290
Commd9
Name: COMM domain containing 9
Synonyms: 1810029F08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76501
Homologene: 8584
Kctd5
Name: potassium channel tetramerisation domain containing 5
Synonyms: 2610030N08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69259
Homologene: 10363
Ift74
Name: intraflagellar transport 74
Synonyms: Cmg1, 1700029H06Rik, Ccdc2, b2b796Clo
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67694
Homologene: 11831
Gp5
Name: glycoprotein 5 platelet
Synonyms: GPV, GP V
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14729
VEGA: 16
HGNC: HGNC:4443
Homologene: 74523
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20264
VEGA: 9
Homologene: 21300
Thra
Name: thyroid hormone receptor alpha
Synonyms: Rvr, 6430529J03Rik, Nr1a1, Thra2, Thra1, T3R[a], T3Ralpha, Erba, TR alpha 2, c-erbAalpha, TR alpha 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21833
Homologene: 37747
C3
Name: complement component 3
Synonyms: Plp, acylation stimulating protein, complement factor 3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Runx2
Name: runt related transcription factor 2
Synonyms: Cbfa1, Pebpa2a, AML3, polyomavirus enhancer binding factor 2 (PEBP2), PEBP2 alpha A, Osf2, SL3-3 enhancer factor 1, PEBP2aA
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12393
Homologene: 68389
Cmtm2a
Name: CKLF-like MARVEL transmembrane domain containing 2A
Synonyms: ARR19, 1700001K04Rik, 1700063K20Rik, 1700041N15Rik, Cklf, Cklfsf2a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73381
Homologene: 88508
Grik4
Name: glutamate receptor, ionotropic, kainate 4
Synonyms: 6330551K01Rik, GluRgamma1, KA-1, KA1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110637
HGNC: HGNC:4582
Homologene: 81829
Cert1
Name: ceramide transporter 1
Synonyms: ceramide transport protein, 2810404O15Rik, Col4a3bp, Cert, 9230101K08Rik, GPBP
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68018
VEGA: 13
HGNC: HGNC:2205
Homologene: 4173
Clstn1
Name: calsyntenin 1
Synonyms: 1810034E21Rik, calsyntenin-1, alcadein alpha, Cst-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 65945
Homologene: 8814
Ssh2
Name: slingshot protein phosphatase 2
Synonyms: SSH-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237860
Homologene: 14116
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX2, prostaglandin G/H synthase, PHS-2, cyclooxygenase 2, PGHS-2, cyclooxygenase-2, Pghs2, Tis10, Cox-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19225
HGNC: HGNC:9605
Homologene: 31000
Myo15a
Name: myosin XVA
Synonyms: Myo15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Cubn
Name: cubilin
Synonyms: intrinsic factor-cobalamin receptor, D2Wsu88e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Tas2r124
Name: taste receptor, type 2, member 124
Synonyms: T2R24, mGR24, Tas2r24, mt2r50
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387351
Homologene: 87293
1700123K08Rik
Name: RIKEN cDNA 1700123K08 gene
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76658
Homologene: 86127
Fat3
Name: FAT atypical cadherin 3
Synonyms: D430038H04Rik, LOC382129, 9430076A06Rik, LOC234973
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75288
Homologene: 45939
Klhl42
Name: kelch-like 42
Synonyms: C230080I20Rik, Klhdc5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232539
Homologene: 45842
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
Lipe
Name: lipase, hormone sensitive
Synonyms: 4933403G17Rik, HSL
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16890
HGNC: HGNC:6621
Homologene: 3912
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: tie-1, D430008P04Rik, TIE
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21846
Homologene: 3957
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Cyp2c39
Name: cytochrome P450, family 2, subfamily c, polypeptide 39
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13098
Homologene: 117948
Cox7a2l
Name: cytochrome c oxidase subunit 7A2 like
Synonyms: COX7RP, SIG81, SIG-81, EB1, Scaf1, COX7AR
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20463
VEGA: 17
HGNC: HGNC:2289
Homologene: 3463
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mar, Mor1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Ndor1
Name: NADPH dependent diflavin oxidoreductase 1
Synonyms: NR1, 4930447P04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78797
Homologene: 7144
Zfp85
Name: zinc finger protein 85
Synonyms: KRAB19, Zfp71, Zfp85-rs1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 22746
Homologene: 133709
Or10j3b
Name: olfactory receptor family 10 subfamily J member 3B
Synonyms: Olfr1404, MOR267-2, GA_x6K02T2R7CC-630397-629456
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258881
Homologene: 133587
Hrh4
Name: histamine receptor H4
Synonyms: H4R
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225192
VEGA: 18
Homologene: 11002
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Mater, Nalp5, Op1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23968
Homologene: 65105
Klra5
Name: killer cell lectin-like receptor, subfamily A, member 5
Synonyms: Ly49e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16636
Homologene: 110821
Gm1527
Name: predicted gene 1527
Synonyms: LOC385263
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 385263
Homologene: 133976
Ces1g
Name: carboxylesterase 1G
Synonyms: Ses-1, Ces-1, Ces1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12623
HGNC: HGNC:1863
Homologene: 137354
Cnnm4
Name: cyclin M4
Synonyms: Acdp4, 5430430O18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 94220
HGNC: HGNC:105
Homologene: 75662
Zfp78
Name: zinc finger protein 78
Synonyms: KRAB12, Zfp77
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330463
Homologene: 128524
Semp2l2b
Name: SUMO/sentrin specific peptidase 2-like 2B
Synonyms: 4930444G20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 114671
Homologene: 130042
Lipo1
Name: lipase, member O1
Synonyms: Gm5097
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 329055
Homologene: 86428
Or51ag1
Name: olfactory receptor family 51 subfamily AG member 1
Synonyms: Olfr610, MOR9-2, GA_x6K02T2PBJ9-6221839-6220892
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259085
Homologene: 17495
Acat3
Name: acetyl-Coenzyme A acetyltransferase 3
Synonyms: ACTL
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224530
HGNC: HGNC:94
Homologene: 55855
Aicda
Name: activation-induced cytidine deaminase
Synonyms: Aid
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11628
Homologene: 7623
Mrgpra6
Name: MAS-related GPR, member A6
Synonyms: MrgA6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381886
Sec61b
Name: SEC61 translocon subunit beta
Synonyms: 1190006C12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66212
Homologene: 38229
B020011L13Rik
Name: RIKEN cDNA B020011L13 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 547097
Homologene: 140625
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 36,472,812 bp (GRCm38)
  • T to C, chromosome 1 at 93,430,292 bp (GRCm38)
  • A to T, chromosome 1 at 117,801,732 bp (GRCm38)
  • T to A, chromosome 1 at 150,105,051 bp (GRCm38)
  • A to T, chromosome 1 at 173,216,467 bp (GRCm38)
  • G to A, chromosome 2 at 13,321,180 bp (GRCm38)
  • T to C, chromosome 2 at 25,248,422 bp (GRCm38)
  • T to C, chromosome 2 at 101,897,091 bp (GRCm38)
  • A to G, chromosome 3 at 28,915,326 bp (GRCm38)
  • A to G, chromosome 4 at 47,483,056 bp (GRCm38)
  • A to T, chromosome 4 at 94,662,585 bp (GRCm38)
  • T to C, chromosome 4 at 118,489,835 bp (GRCm38)
  • A to G, chromosome 4 at 149,638,300 bp (GRCm38)
  • A to G, chromosome 5 at 44,007,057 bp (GRCm38)
  • T to C, chromosome 5 at 138,563,552 bp (GRCm38)
  • T to A, chromosome 6 at 122,561,154 bp (GRCm38)
  • C to A, chromosome 6 at 129,906,723 bp (GRCm38)
  • C to T, chromosome 6 at 132,755,529 bp (GRCm38)
  • T to C, chromosome 6 at 147,107,875 bp (GRCm38)
  • T to A, chromosome 7 at 6,379,075 bp (GRCm38)
  • C to T, chromosome 7 at 23,408,136 bp (GRCm38)
  • T to A, chromosome 7 at 25,397,901 bp (GRCm38)
  • A to T, chromosome 7 at 28,407,289 bp (GRCm38)
  • T to A, chromosome 7 at 47,185,927 bp (GRCm38)
  • C to T, chromosome 7 at 103,506,520 bp (GRCm38)
  • T to A, chromosome 7 at 120,527,181 bp (GRCm38)
  • G to A, chromosome 8 at 85,284,004 bp (GRCm38)
  • A to G, chromosome 8 at 93,335,179 bp (GRCm38)
  • A to G, chromosome 8 at 104,292,654 bp (GRCm38)
  • T to C, chromosome 9 at 16,378,047 bp (GRCm38)
  • T to A, chromosome 9 at 42,591,469 bp (GRCm38)
  • C to T, chromosome 9 at 108,107,231 bp (GRCm38)
  • A to G, chromosome 9 at 119,658,438 bp (GRCm38)
  • T to C, chromosome 10 at 22,067,712 bp (GRCm38)
  • A to T, chromosome 11 at 60,483,494 bp (GRCm38)
  • A to G, chromosome 11 at 77,425,377 bp (GRCm38)
  • G to A, chromosome 11 at 98,760,889 bp (GRCm38)
  • T to A, chromosome 11 at 101,575,152 bp (GRCm38)
  • G to A, chromosome 12 at 109,590,401 bp (GRCm38)
  • G to A, chromosome 13 at 9,575,155 bp (GRCm38)
  • A to G, chromosome 13 at 67,749,207 bp (GRCm38)
  • C to T, chromosome 13 at 96,630,826 bp (GRCm38)
  • A to G, chromosome 14 at 49,318,849 bp (GRCm38)
  • A to T, chromosome 14 at 78,575,930 bp (GRCm38)
  • C to A, chromosome 15 at 76,737,238 bp (GRCm38)
  • A to C, chromosome 16 at 30,309,575 bp (GRCm38)
  • G to A, chromosome 17 at 12,928,615 bp (GRCm38)
  • A to T, chromosome 17 at 24,073,218 bp (GRCm38)
  • C to A, chromosome 17 at 24,982,809 bp (GRCm38)
  • A to C, chromosome 17 at 30,998,178 bp (GRCm38)
  • A to T, chromosome 17 at 44,658,673 bp (GRCm38)
  • A to T, chromosome 17 at 57,211,669 bp (GRCm38)
  • A to G, chromosome 17 at 83,514,272 bp (GRCm38)
  • C to A, chromosome 18 at 13,021,887 bp (GRCm38)
  • T to C, chromosome 19 at 33,776,647 bp (GRCm38)
  • T to C, chromosome 19 at 39,513,173 bp (GRCm38)
  • T to A, chromosome 19 at 53,380,520 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9615 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069408-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.