Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9615Btlr/Mmmh
Stock Number:
069408-MU
Citation ID:
RRID:MMRRC_069408-MU
Other Names:
R9615 (G1)
Major Collection:

Strain Information

Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223666
Homologene: 27825
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Dgkh
Name: diacylglycerol kinase, eta
Synonyms: 5930402B05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380921
VEGA: 14
HGNC: HGNC:2854
Homologene: 99373
Hdlbp
Name: high density lipoprotein (HDL) binding protein
Synonyms: D1Ertd101e, 1110005P14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 110611
HGNC: HGNC:4857
Homologene: 38035
Samd4b
Name: sterile alpha motif domain containing 4B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233033
Homologene: 35268
Vps35
Name: VPS35 retromer complex component
Synonyms: Mem3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 65114
Homologene: 6221
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 36,472,812 bp (GRCm38)
  • T to C, chromosome 1 at 93,430,292 bp (GRCm38)
  • A to T, chromosome 1 at 117,801,732 bp (GRCm38)
  • T to A, chromosome 1 at 150,105,051 bp (GRCm38)
  • A to T, chromosome 1 at 173,216,467 bp (GRCm38)
  • G to A, chromosome 2 at 13,321,180 bp (GRCm38)
  • T to C, chromosome 2 at 25,248,422 bp (GRCm38)
  • T to C, chromosome 2 at 101,897,091 bp (GRCm38)
  • A to G, chromosome 3 at 28,915,326 bp (GRCm38)
  • A to G, chromosome 4 at 47,483,056 bp (GRCm38)
  • A to T, chromosome 4 at 94,662,585 bp (GRCm38)
  • T to C, chromosome 4 at 118,489,835 bp (GRCm38)
  • A to G, chromosome 4 at 149,638,300 bp (GRCm38)
  • A to G, chromosome 5 at 44,007,057 bp (GRCm38)
  • T to C, chromosome 5 at 138,563,552 bp (GRCm38)
  • T to A, chromosome 6 at 122,561,154 bp (GRCm38)
  • C to A, chromosome 6 at 129,906,723 bp (GRCm38)
  • C to T, chromosome 6 at 132,755,529 bp (GRCm38)
  • T to C, chromosome 6 at 147,107,875 bp (GRCm38)
  • T to A, chromosome 7 at 6,379,075 bp (GRCm38)
  • C to T, chromosome 7 at 23,408,136 bp (GRCm38)
  • T to A, chromosome 7 at 25,397,901 bp (GRCm38)
  • A to T, chromosome 7 at 28,407,289 bp (GRCm38)
  • T to A, chromosome 7 at 47,185,927 bp (GRCm38)
  • C to T, chromosome 7 at 103,506,520 bp (GRCm38)
  • T to A, chromosome 7 at 120,527,181 bp (GRCm38)
  • G to A, chromosome 8 at 85,284,004 bp (GRCm38)
  • A to G, chromosome 8 at 93,335,179 bp (GRCm38)
  • A to G, chromosome 8 at 104,292,654 bp (GRCm38)
  • T to C, chromosome 9 at 16,378,047 bp (GRCm38)
  • T to A, chromosome 9 at 42,591,469 bp (GRCm38)
  • C to T, chromosome 9 at 108,107,231 bp (GRCm38)
  • A to G, chromosome 9 at 119,658,438 bp (GRCm38)
  • T to C, chromosome 10 at 22,067,712 bp (GRCm38)
  • A to T, chromosome 11 at 60,483,494 bp (GRCm38)
  • A to G, chromosome 11 at 77,425,377 bp (GRCm38)
  • G to A, chromosome 11 at 98,760,889 bp (GRCm38)
  • T to A, chromosome 11 at 101,575,152 bp (GRCm38)
  • G to A, chromosome 12 at 109,590,401 bp (GRCm38)
  • G to A, chromosome 13 at 9,575,155 bp (GRCm38)
  • A to G, chromosome 13 at 67,749,207 bp (GRCm38)
  • C to T, chromosome 13 at 96,630,826 bp (GRCm38)
  • A to G, chromosome 14 at 49,318,849 bp (GRCm38)
  • A to T, chromosome 14 at 78,575,930 bp (GRCm38)
  • C to A, chromosome 15 at 76,737,238 bp (GRCm38)
  • A to C, chromosome 16 at 30,309,575 bp (GRCm38)
  • G to A, chromosome 17 at 12,928,615 bp (GRCm38)
  • A to T, chromosome 17 at 24,073,218 bp (GRCm38)
  • C to A, chromosome 17 at 24,982,809 bp (GRCm38)
  • A to C, chromosome 17 at 30,998,178 bp (GRCm38)
  • A to T, chromosome 17 at 44,658,673 bp (GRCm38)
  • A to T, chromosome 17 at 57,211,669 bp (GRCm38)
  • A to G, chromosome 17 at 83,514,272 bp (GRCm38)
  • C to A, chromosome 18 at 13,021,887 bp (GRCm38)
  • T to C, chromosome 19 at 33,776,647 bp (GRCm38)
  • T to C, chromosome 19 at 39,513,173 bp (GRCm38)
  • T to A, chromosome 19 at 53,380,520 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9615 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069408-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.