Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9623Btlr/Mmmh
Stock Number:
069416-MU
Citation ID:
RRID:MMRRC_069416-MU
Other Names:
R9623 (G1)
Major Collection:

Strain Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: dyn, SpbIV, neuroaxonal dystrophy, 5830426A08Rik, ROSA62, nmf261, 1700022P15Rik, Spnb4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80297
Homologene: 11879
Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Arhgap10
Name: Rho GTPase activating protein 10
Synonyms: PSGAP-s, PSGAP-m, A930033B01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78514
Homologene: 12695
Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22427
Homologene: 6659
Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, bNOS, Nos-1, NO, 2310005C01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Nrcam
Name: neuronal cell adhesion molecule
Synonyms: Bravo, C030017F07Rik, C130076O07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319504
VEGA: 12
HGNC: HGNC:7994
Homologene: 21041
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 116,442,255 bp (GRCm38)
  • G to A, chromosome 1 at 182,517,230 bp (GRCm38)
  • C to T, chromosome 2 at 6,615,711 bp (GRCm38)
  • A to G, chromosome 2 at 20,806,241 bp (GRCm38)
  • A to T, chromosome 2 at 25,609,508 bp (GRCm38)
  • G to T, chromosome 2 at 36,688,766 bp (GRCm38)
  • C to T, chromosome 2 at 41,476,636 bp (GRCm38)
  • A to G, chromosome 2 at 50,296,329 bp (GRCm38)
  • T to C, chromosome 2 at 69,477,079 bp (GRCm38)
  • T to A, chromosome 2 at 69,881,373 bp (GRCm38)
  • A to G, chromosome 2 at 89,590,917 bp (GRCm38)
  • T to C, chromosome 2 at 120,934,339 bp (GRCm38)
  • T to G, chromosome 2 at 125,115,457 bp (GRCm38)
  • G to A, chromosome 2 at 181,647,344 bp (GRCm38)
  • A to T, chromosome 3 at 93,796,914 bp (GRCm38)
  • A to G, chromosome 3 at 95,772,193 bp (GRCm38)
  • T to C, chromosome 3 at 123,114,398 bp (GRCm38)
  • T to G, chromosome 3 at 145,013,937 bp (GRCm38)
  • A to G, chromosome 4 at 43,496,819 bp (GRCm38)
  • T to C, chromosome 4 at 58,785,585 bp (GRCm38)
  • A to G, chromosome 4 at 90,224,891 bp (GRCm38)
  • A to T, chromosome 4 at 139,074,439 bp (GRCm38)
  • A to G, chromosome 4 at 139,431,713 bp (GRCm38)
  • T to G, chromosome 4 at 149,749,310 bp (GRCm38)
  • A to C, chromosome 5 at 23,965,257 bp (GRCm38)
  • G to A, chromosome 5 at 34,917,732 bp (GRCm38)
  • G to T, chromosome 5 at 71,633,680 bp (GRCm38)
  • A to G, chromosome 5 at 91,613,064 bp (GRCm38)
  • A to G, chromosome 5 at 117,949,784 bp (GRCm38)
  • A to G, chromosome 5 at 122,652,797 bp (GRCm38)
  • G to A, chromosome 5 at 137,463,374 bp (GRCm38)
  • T to A, chromosome 6 at 29,405,940 bp (GRCm38)
  • T to C, chromosome 6 at 43,274,802 bp (GRCm38)
  • T to G, chromosome 6 at 57,210,564 bp (GRCm38)
  • T to A, chromosome 6 at 66,612,018 bp (GRCm38)
  • T to C, chromosome 6 at 71,215,824 bp (GRCm38)
  • G to T, chromosome 6 at 92,880,680 bp (GRCm38)
  • T to C, chromosome 6 at 123,286,347 bp (GRCm38)
  • A to G, chromosome 6 at 149,325,467 bp (GRCm38)
  • A to G, chromosome 7 at 6,961,397 bp (GRCm38)
  • T to A, chromosome 7 at 25,081,090 bp (GRCm38)
  • A to G, chromosome 7 at 27,408,382 bp (GRCm38)
  • A to G, chromosome 7 at 44,956,507 bp (GRCm38)
  • A to G, chromosome 7 at 68,740,993 bp (GRCm38)
  • A to T, chromosome 7 at 101,664,192 bp (GRCm38)
  • A to G, chromosome 7 at 105,686,566 bp (GRCm38)
  • G to A, chromosome 7 at 105,694,927 bp (GRCm38)
  • A to G, chromosome 7 at 110,803,100 bp (GRCm38)
  • A to T, chromosome 7 at 119,582,752 bp (GRCm38)
  • A to G, chromosome 7 at 126,412,112 bp (GRCm38)
  • A to T, chromosome 7 at 127,245,129 bp (GRCm38)
  • A to G, chromosome 7 at 128,204,551 bp (GRCm38)
  • G to A, chromosome 7 at 141,441,765 bp (GRCm38)
  • A to G, chromosome 8 at 33,284,616 bp (GRCm38)
  • T to C, chromosome 8 at 77,259,157 bp (GRCm38)
  • G to T, chromosome 8 at 106,160,643 bp (GRCm38)
  • A to G, chromosome 8 at 114,418,147 bp (GRCm38)
  • G to A, chromosome 8 at 117,187,480 bp (GRCm38)
  • A to T, chromosome 9 at 48,592,360 bp (GRCm38)
  • T to C, chromosome 9 at 78,457,430 bp (GRCm38)
  • T to A, chromosome 9 at 110,989,532 bp (GRCm38)
  • C to A, chromosome 9 at 121,762,924 bp (GRCm38)
  • A to T, chromosome 10 at 5,202,009 bp (GRCm38)
  • C to T, chromosome 10 at 12,406,481 bp (GRCm38)
  • T to G, chromosome 10 at 14,130,802 bp (GRCm38)
  • T to C, chromosome 10 at 78,037,975 bp (GRCm38)
  • A to T, chromosome 10 at 91,077,601 bp (GRCm38)
  • C to A, chromosome 10 at 115,423,457 bp (GRCm38)
  • T to C, chromosome 10 at 130,479,925 bp (GRCm38)
  • G to T, chromosome 11 at 52,004,989 bp (GRCm38)
  • T to C, chromosome 11 at 68,551,333 bp (GRCm38)
  • G to C, chromosome 12 at 44,590,148 bp (GRCm38)
  • A to G, chromosome 12 at 75,939,986 bp (GRCm38)
  • A to T, chromosome 12 at 87,160,149 bp (GRCm38)
  • A to G, chromosome 12 at 104,217,484 bp (GRCm38)
  • A to G, chromosome 13 at 3,887,569 bp (GRCm38)
  • G to T, chromosome 13 at 13,678,002 bp (GRCm38)
  • T to C, chromosome 13 at 21,520,593 bp (GRCm38)
  • A to G, chromosome 14 at 54,726,884 bp (GRCm38)
  • G to T, chromosome 14 at 55,064,734 bp (GRCm38)
  • G to A, chromosome 15 at 76,890,331 bp (GRCm38)
  • T to C, chromosome 15 at 102,484,193 bp (GRCm38)
  • G to C, chromosome 16 at 22,566,444 bp (GRCm38)
  • G to A, chromosome 16 at 35,622,751 bp (GRCm38)
  • G to T, chromosome 16 at 44,501,655 bp (GRCm38)
  • A to G, chromosome 17 at 23,737,682 bp (GRCm38)
  • C to A, chromosome 17 at 24,249,393 bp (GRCm38)
  • A to T, chromosome 17 at 35,514,895 bp (GRCm38)
  • T to A, chromosome 18 at 20,850,918 bp (GRCm38)
  • A to G, chromosome 18 at 46,175,556 bp (GRCm38)
  • T to A, chromosome 19 at 5,463,822 bp (GRCm38)
  • C to A, chromosome 19 at 13,655,050 bp (GRCm38)
  • A to G, chromosome 19 at 46,888,970 bp (GRCm38)
  • T to A, chromosome 19 at 56,918,030 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9623 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069416-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.