Strain Name:
C57BL/6J-MtgxR9633Btlr/Mmmh
Stock Number:
069426-MU
Citation ID:
RRID:MMRRC_069426-MU
Other Names:
R9633 (G1)
Major Collection:

Strain Information

Upp1
Name: uridine phosphorylase 1
Synonyms: Up, UPase, UdRPase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22271
Homologene: 2524
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Fgfr-1, Fr1, Hspy, FGFR-I, Eask, Flt-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Rgs4
Name: regulator of G-protein signaling 4
Synonyms: ESTM48, ESTM50
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19736
Homologene: 4100
Tcf4
Name: transcription factor 4
Synonyms: ME2, MITF-2B, E2-2, ASP-I2, SEF-2, E2.2, 5730422P05Rik, ITF-2, ITF-2b, MITF-2A, SEF2-1, bHLHb19, TFE
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 21413
Homologene: 2407
Wwc2
Name: WW, C2 and coiled-coil domain containing 2
Synonyms: D8Ertd594e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52357
Homologene: 32618
Zfp318
Name: zinc finger protein 318
Synonyms: TZF, 2610034E08Rik, D530032D06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57908
Homologene: 22808
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Tmem131
Name: transmembrane protein 131
Synonyms: CC28, YR-23, D1Bwg0491e, Rw1, Neg, 2610524E03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56030
Homologene: 32428
Mmadhc
Name: methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
Synonyms: 2010311D03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 109129
Homologene: 9248
Lrrtm4
Name: leucine rich repeat transmembrane neuronal 4
Synonyms: 7530419J18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243499
Homologene: 11807
Maea
Name: macrophage erythroblast attacher
Synonyms: Gid9, 1110030D19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59003
Homologene: 4298
Mfsd14b
Name: major facilitator superfamily domain containing 14B
Synonyms: 5730414C17Rik, Hiatl1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66631
Homologene: 64464
Ubxn7
Name: UBX domain protein 7
Synonyms: Ubxd7
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224111
VEGA: 16
Homologene: 45585
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217351
Homologene: 23137
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Psrc2, Ccdc131
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216345
Homologene: 17017
Nkx2-2
Name: NK2 homeobox 2
Synonyms: Nkx-2.2, tinman, Nkx2.2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18088
HGNC: HGNC:7835
Homologene: 1879
Avl9
Name: AVL9 cell migration associated
Synonyms: D730049P16Rik, 5830411G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78937
Homologene: 62425
Spocd1
Name: SPOC domain containing 1
Synonyms: OTTMUSG00000009522
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 622480
Homologene: 83439
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269902
Homologene: 104832
Afap1l1
Name: actin filament associated protein 1-like 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 106877
Homologene: 18728
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Vmn1r213
Name: vomeronasal 1 receptor 213
Synonyms: V1rh6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171249
Homologene: 110880
Psmb9
Name: proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Synonyms: Lmp2, Lmp-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16912
HGNC: HGNC:9546
Homologene: 2094
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 3830402K23Rik, 4930518F03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320558
Homologene: 8604
Izumo3
Name: IZUMO family member 3
Synonyms: 1700011H22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69314
Homologene: 122080
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241919
Homologene: 76320
Lingo2
Name: leucine rich repeat and Ig domain containing 2
Synonyms: LERN3, Lrrn6c, B230217C06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242384
Homologene: 17621
Erich6
Name: glutamate rich 6
Synonyms: Fam194a, 4932431H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 545527
Homologene: 65043
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: 9330209L04Rik, Mamdc1, Adp, Mdga2, 6720489L24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320772
Homologene: 45659
Atf6b
Name: activating transcription factor 6 beta
Synonyms: Creb-rp, ATF6beta, Crebl1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12915
HGNC: HGNC:2349
Homologene: 31238
Vmn1r235
Name: vomeronasal 1 receptor 235
Synonyms: V1rf2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171233
Homologene: 74360
F830016B08Rik
Name: RIKEN cDNA F830016B08 gene
Synonyms: Ifgga4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240328
VEGA: 18
Homologene: 129714
Unc5c
Name: unc-5 netrin receptor C
Synonyms: B130051O18Rik, Unc5h3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22253
Homologene: 2765
Slc26a7
Name: solute carrier family 26, member 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 208890
Homologene: 13770
Kcnb2
Name: potassium voltage gated channel, Shab-related subfamily, member 2
Synonyms: 9630047L19Rik, Kv2.2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98741
HGNC: HGNC:6232
Homologene: 31263
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: 2010309H15Rik, Thea, BFIT1, Them1, 1110020M10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329910
Homologene: 11977
Pramel14
Name: PRAME like 14
Synonyms: Pramef17, Gm13107
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 626943
Homologene: 129642
Gnat2
Name: G protein subunit alpha transducin 2
Synonyms: Tcalpha, Gt-2, Gnat-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14686
HGNC: HGNC:4394
Homologene: 21092
Slc22a14
Name: solute carrier family 22 (organic cation transporter), member 14
Synonyms: LOC382113
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382113
HGNC: HGNC:8495
Homologene: 3530
Ceacam3
Name: CEA cell adhesion molecule 3
Synonyms: cea12, Psg24, EG384557
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384557
HGNC: HGNC:1819
Homologene: 86971
Krt6b
Name: keratin 6B
Synonyms: Krt2-6b, mK6[b]
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16688
VEGA: 15
Homologene: 136794
Tktl2
Name: transketolase-like 2
Synonyms: 4933401I19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74419
Homologene: 69456
Fmo4
Name: flavin containing monooxygenase 4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226564
HGNC: HGNC:3772
Homologene: 68219
N4bp2l2
Name: NEDD4 binding protein 2-like 2
Synonyms: zag1, 2700092H06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381695
Homologene: 115380
Kcnrg
Name: potassium channel regulator
Synonyms: E030012H22Rik, LOC328424
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328424
VEGA: 14
Homologene: 35259
Ms4a8a
Name: membrane-spanning 4-domains, subfamily A, member 8A
Synonyms: CD20L5, 2010004L09Rik, Ms4a8
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 64381
Homologene: 111037
Tomm5
Name: translocase of outer mitochondrial membrane 5
Synonyms: 1110019J04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68512
Homologene: 104342
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 15,711,220 bp (GRCm38)
  • A to T, chromosome 1 at 36,807,988 bp (GRCm38)
  • T to A, chromosome 1 at 162,803,622 bp (GRCm38)
  • T to A, chromosome 1 at 169,745,274 bp (GRCm38)
  • A to T, chromosome 2 at 50,288,976 bp (GRCm38)
  • A to G, chromosome 2 at 147,185,766 bp (GRCm38)
  • A to G, chromosome 2 at 178,356,461 bp (GRCm38)
  • T to A, chromosome 3 at 31,224,017 bp (GRCm38)
  • T to C, chromosome 3 at 58,629,856 bp (GRCm38)
  • T to A, chromosome 3 at 108,095,454 bp (GRCm38)
  • A to C, chromosome 3 at 141,789,893 bp (GRCm38)
  • G to A, chromosome 4 at 14,524,540 bp (GRCm38)
  • A to G, chromosome 4 at 35,709,885 bp (GRCm38)
  • G to A, chromosome 4 at 45,107,982 bp (GRCm38)
  • T to A, chromosome 4 at 92,146,558 bp (GRCm38)
  • A to G, chromosome 4 at 106,755,981 bp (GRCm38)
  • T to C, chromosome 4 at 129,956,670 bp (GRCm38)
  • T to C, chromosome 4 at 143,994,248 bp (GRCm38)
  • T to A, chromosome 5 at 33,368,706 bp (GRCm38)
  • A to T, chromosome 5 at 150,661,638 bp (GRCm38)
  • T to A, chromosome 6 at 56,730,649 bp (GRCm38)
  • C to T, chromosome 6 at 80,023,081 bp (GRCm38)
  • T to A, chromosome 6 at 85,623,143 bp (GRCm38)
  • A to G, chromosome 7 at 17,161,763 bp (GRCm38)
  • T to C, chromosome 7 at 41,426,582 bp (GRCm38)
  • G to A, chromosome 7 at 44,312,918 bp (GRCm38)
  • C to A, chromosome 7 at 119,950,993 bp (GRCm38)
  • T to A, chromosome 8 at 25,570,760 bp (GRCm38)
  • GCC to GCCC, chromosome 8 at 47,851,924 bp (GRCm38)
  • T to C, chromosome 8 at 66,513,161 bp (GRCm38)
  • A to G, chromosome 9 at 119,179,462 bp (GRCm38)
  • T to A, chromosome 10 at 115,411,947 bp (GRCm38)
  • G to A, chromosome 11 at 9,134,909 bp (GRCm38)
  • G to A, chromosome 11 at 117,747,183 bp (GRCm38)
  • T to C, chromosome 12 at 66,689,432 bp (GRCm38)
  • A to G, chromosome 13 at 23,011,349 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • CACAACAA to CACAA, chromosome 14 at 61,607,560 bp (GRCm38)
  • C to T, chromosome 15 at 101,678,561 bp (GRCm38)
  • T to C, chromosome 16 at 32,381,430 bp (GRCm38)
  • G to T, chromosome 17 at 21,262,067 bp (GRCm38)
  • G to T, chromosome 17 at 21,262,068 bp (GRCm38)
  • T to A, chromosome 17 at 34,183,145 bp (GRCm38)
  • T to A, chromosome 17 at 34,653,533 bp (GRCm38)
  • T to A, chromosome 17 at 46,399,495 bp (GRCm38)
  • A to T, chromosome 18 at 60,299,893 bp (GRCm38)
  • A to C, chromosome 18 at 61,757,724 bp (GRCm38)
  • A to T, chromosome 18 at 69,593,311 bp (GRCm38)
  • A to G, chromosome 19 at 11,079,592 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9633 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069426-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.