Strain Name:
C57BL/6J-MtgxR9635Btlr/Mmmh
Stock Number:
069428-MU
Citation ID:
RRID:MMRRC_069428-MU
Other Names:
R9635 (G1)
Major Collection:

Strain Information

Dnmbp
Name: dynamin binding protein
Synonyms: 2410003M15Rik, Tuba, 2410003L07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71972
Homologene: 9061
Akap9
Name: A kinase anchor protein 9
Synonyms: G1-448-15, 5730481H23Rik, mei2-5, AKAP450, repro12
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Prc1
Name: protein regulator of cytokinesis 1
Synonyms: D7Ertd348e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233406
HGNC: HGNC:9341
Homologene: 37868
Zfp512
Name: zinc finger protein 512
Synonyms: 2500002M11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269639
Homologene: 13026
Rbm34
Name: RNA binding motif protein 34
Synonyms: 4930547K05Rik, D8Ertd233e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52202
Homologene: 56691
Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: Zak, MLTKalpha, MLTKbeta, B230120H23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 65964
Homologene: 32331
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Vdac3
Name: voltage-dependent anion channel 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22335
Homologene: 36115
Ppp4r3b
Name: protein phosphatase 4 regulatory subunit 3B
Synonyms: Smek2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104570
Homologene: 68886
AW209491
Name: expressed sequence AW209491
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105351
VEGA: 13
Homologene: 11439
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212168
Homologene: 18183
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 192188
Homologene: 23022
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242274
Homologene: 10817
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Pcdhb5
Name: protocadherin beta 5
Synonyms: PcdhbE, Pcdhb4A
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Vmn1r124
Name: vomeronasal 1 receptor 124
Synonyms: Gm9500
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670764
Homologene: 104166
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: 4930532L22Rik, B230399N07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269610
Homologene: 56712
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194357
Homologene: 77226
Trim10
Name: tripartite motif-containing 10
Synonyms: Rnf9, Herf1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19824
Homologene: 4932
Cfhr4
Name: complement factor H-related 4
Synonyms: Gm4788
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214403
HGNC: HGNC:4883
Slc34a1
Name: solute carrier family 34 (sodium phosphate), member 1
Synonyms: Npt2, Slc17a2, renal Na+/Pi transporter, NaPi-IIa, Na/Pi cotransporter
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20505
VEGA: 13
Homologene: 20663
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Or5p79
Name: olfactory receptor family 5 subfamily P member 79
Synonyms: MOR204-7, GA_x6K02T2PBJ9-10951546-10952496, Olfr507
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258738
Homologene: 27249
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52372
Or6c5c
Name: olfactory receptor family 6 subfamily C member 5C
Synonyms: GA_x6K02T2PULF-11141498-11142436, MOR111-10, Olfr787
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258069
Homologene: 105326
Gm10322
Name: predicted gene 10322
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 100039225
Samsn1
Name: SAM domain, SH3 domain and nuclear localization signals, 1
Synonyms: Hacs1, 4930571B16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67742
Homologene: 11148
Cyp3a41a
Name: cytochrome P450, family 3, subfamily a, polypeptide 41A
Synonyms: steroid inducible, Cyp3a41
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53973
HGNC: HGNC:2638
Homologene: 133568
Best3
Name: bestrophin 3
Synonyms: mBest4, Vmd2l3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 382427
VEGA: 10
Homologene: 33850
Cabyr
Name: calcium binding tyrosine phosphorylation regulated
Synonyms: CBP86, 1700016C01Rik, FSP-2, 4933421A18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71132
Homologene: 49299
Gal3st2b
Name: galactose-3-O-sulfotransferase 2B
Synonyms: Gm9994
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100041596
Homologene: 41471
Pdcd2l
Name: programmed cell death 2-like
Synonyms: 6030457N17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68079
Homologene: 41861
Ighe
Name: Immunoglobulin heavy constant epsilon
Synonyms: Gm900, LOC380792
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380792
HGNC: HGNC:5522
Commd2
Name: COMM domain containing 2
Synonyms: HSPC042, D3Ertd176e, 1190017G07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 52245
Homologene: 9381
Zdhhc22
Name: zinc finger, DHHC-type containing 22
Synonyms: LOC238331
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238331
VEGA: 12
Homologene: 45486
Gm10309
Name: predicted gene 10309
Type: Gene
Species: Mouse
Chromosome: 17
Ubxn6
Name: UBX domain protein 6
Synonyms: Ubxd1, Ubxdc2, 2210415J11Rik, 1200008L11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66530
Homologene: 11538
Trpv6
Name: transient receptor potential cation channel, subfamily V, member 6
Synonyms: CAT, Ecac2, CaT1, Cac
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 64177
Homologene: 56812
Cox5b-ps
Name: cytochrome c oxidase subunit 5B, pseudogene
Synonyms: Gm11273
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100040340
Gpr17
Name: G protein-coupled receptor 17
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 574402
HGNC: HGNC:4471
Homologene: 83191
Or4f4-ps1
Name: olfactory receptor family 4 subfamily F member 4, pseudogene 1
Synonyms: Olfr1291, Olfr1291-ps1, MOR245-32_p, GA_x6K02T2Q125-72550790-72551728, OTTMUSG00000015084
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257819
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 93,941,055 bp (GRCm38)
  • C to T, chromosome 1 at 139,774,026 bp (GRCm38)
  • G to A, chromosome 2 at 72,402,059 bp (GRCm38)
  • C to T, chromosome 2 at 76,756,273 bp (GRCm38)
  • T to A, chromosome 2 at 111,499,922 bp (GRCm38)
  • T to C, chromosome 3 at 57,651,643 bp (GRCm38)
  • T to C, chromosome 3 at 158,240,501 bp (GRCm38)
  • A to T, chromosome 4 at 152,376,622 bp (GRCm38)
  • A to T, chromosome 5 at 4,050,545 bp (GRCm38)
  • A to G, chromosome 5 at 31,466,325 bp (GRCm38)
  • A to T, chromosome 5 at 145,715,510 bp (GRCm38)
  • T to A, chromosome 6 at 40,886,066 bp (GRCm38)
  • T to C, chromosome 6 at 41,622,967 bp (GRCm38)
  • G to C, chromosome 6 at 87,111,857 bp (GRCm38)
  • G to A, chromosome 7 at 21,259,795 bp (GRCm38)
  • A to C, chromosome 7 at 28,101,407 bp (GRCm38)
  • A to C, chromosome 7 at 34,192,931 bp (GRCm38)
  • T to G, chromosome 7 at 80,312,299 bp (GRCm38)
  • A to G, chromosome 7 at 108,622,447 bp (GRCm38)
  • A to T, chromosome 8 at 22,587,559 bp (GRCm38)
  • A to T, chromosome 8 at 54,648,340 bp (GRCm38)
  • T to C, chromosome 8 at 84,212,725 bp (GRCm38)
  • A to G, chromosome 8 at 126,970,122 bp (GRCm38)
  • A to T, chromosome 10 at 59,616,109 bp (GRCm38)
  • T to A, chromosome 10 at 86,850,787 bp (GRCm38)
  • A to T, chromosome 10 at 117,002,545 bp (GRCm38)
  • T to C, chromosome 10 at 129,463,594 bp (GRCm38)
  • T to C, chromosome 11 at 29,188,113 bp (GRCm38)
  • T to C, chromosome 11 at 59,081,860 bp (GRCm38)
  • A to G, chromosome 12 at 86,983,622 bp (GRCm38)
  • T to C, chromosome 12 at 113,272,279 bp (GRCm38)
  • T to C, chromosome 13 at 14,637,372 bp (GRCm38)
  • T to C, chromosome 13 at 21,501,124 bp (GRCm38)
  • G to A, chromosome 13 at 55,409,127 bp (GRCm38)
  • T to A, chromosome 15 at 91,812,324 bp (GRCm38)
  • T to G, chromosome 16 at 75,876,569 bp (GRCm38)
  • G to A, chromosome 17 at 36,876,998 bp (GRCm38)
  • A to G, chromosome 17 at 56,069,189 bp (GRCm38)
  • T to C, chromosome 17 at 86,499,066 bp (GRCm38)
  • A to G, chromosome 18 at 12,750,759 bp (GRCm38)
  • A to G, chromosome 18 at 31,947,146 bp (GRCm38)
  • A to T, chromosome 18 at 37,321,457 bp (GRCm38)
  • C to A, chromosome 19 at 43,867,535 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9635 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069428-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.