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Strain Name:
C57BL/6J-MtgxR9660Btlr/Mmmh
Stock Number:
069453-MU
Citation ID:
RRID:MMRRC_069453-MU
Other Names:
R9660 (G1)
Major Collection:

Strain Information

Setd5
Name: SET domain containing 5
Synonyms: 2900045N06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 72895
Homologene: 12485
Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, OB-cadherin, Cad11
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Myo1e
Name: myosin IE
Synonyms: 2310020N23Rik, 9130023P14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, D230038D11Rik, 9530077A04Rik, Mll5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69188
Homologene: 18822
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20513
VEGA: 10
Homologene: 21055
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77595
Homologene: 28122
Sik3
Name: SIK family kinase 3
Synonyms: 5730525O22Rik, 9030204A07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70661
Homologene: 57023
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 69,923,683 bp (GRCm38)
  • A to G, chromosome 1 at 134,987,507 bp (GRCm38)
  • A to G, chromosome 1 at 171,359,789 bp (GRCm38)
  • C to A, chromosome 2 at 18,699,236 bp (GRCm38)
  • C to T, chromosome 2 at 25,398,141 bp (GRCm38)
  • A to G, chromosome 2 at 60,323,840 bp (GRCm38)
  • T to C, chromosome 2 at 76,768,808 bp (GRCm38)
  • C to T, chromosome 2 at 76,885,013 bp (GRCm38)
  • T to C, chromosome 2 at 88,728,798 bp (GRCm38)
  • T to C, chromosome 2 at 88,746,528 bp (GRCm38)
  • T to G, chromosome 2 at 111,379,894 bp (GRCm38)
  • T to G, chromosome 2 at 112,833,729 bp (GRCm38)
  • T to C, chromosome 2 at 118,790,146 bp (GRCm38)
  • T to C, chromosome 2 at 143,989,258 bp (GRCm38)
  • T to A, chromosome 2 at 167,989,726 bp (GRCm38)
  • A to G, chromosome 3 at 90,198,095 bp (GRCm38)
  • C to T, chromosome 3 at 90,199,866 bp (GRCm38)
  • A to G, chromosome 3 at 129,996,773 bp (GRCm38)
  • A to G, chromosome 4 at 48,051,353 bp (GRCm38)
  • T to C, chromosome 5 at 23,478,619 bp (GRCm38)
  • A to T, chromosome 5 at 73,408,286 bp (GRCm38)
  • A to G, chromosome 5 at 134,154,138 bp (GRCm38)
  • C to T, chromosome 5 at 134,504,762 bp (GRCm38)
  • C to T, chromosome 5 at 137,564,504 bp (GRCm38)
  • T to C, chromosome 6 at 28,420,545 bp (GRCm38)
  • A to T, chromosome 6 at 41,141,616 bp (GRCm38)
  • G to A, chromosome 6 at 48,455,773 bp (GRCm38)
  • G to T, chromosome 6 at 69,764,983 bp (GRCm38)
  • A to G, chromosome 6 at 87,902,243 bp (GRCm38)
  • G to T, chromosome 6 at 113,151,405 bp (GRCm38)
  • G to T, chromosome 6 at 118,466,890 bp (GRCm38)
  • C to A, chromosome 6 at 125,591,707 bp (GRCm38)
  • T to A, chromosome 7 at 26,557,490 bp (GRCm38)
  • C to A, chromosome 7 at 98,449,857 bp (GRCm38)
  • A to G, chromosome 7 at 98,613,078 bp (GRCm38)
  • G to T, chromosome 7 at 102,112,209 bp (GRCm38)
  • C to T, chromosome 7 at 102,942,052 bp (GRCm38)
  • A to G, chromosome 7 at 120,252,255 bp (GRCm38)
  • A to T, chromosome 7 at 122,007,271 bp (GRCm38)
  • A to C, chromosome 7 at 125,663,027 bp (GRCm38)
  • A to G, chromosome 8 at 21,794,470 bp (GRCm38)
  • C to T, chromosome 8 at 102,658,247 bp (GRCm38)
  • T to C, chromosome 8 at 119,462,664 bp (GRCm38)
  • A to T, chromosome 8 at 125,760,853 bp (GRCm38)
  • A to G, chromosome 9 at 46,194,844 bp (GRCm38)
  • A to G, chromosome 9 at 70,316,642 bp (GRCm38)
  • G to T, chromosome 9 at 89,091,342 bp (GRCm38)
  • G to A, chromosome 9 at 95,914,997 bp (GRCm38)
  • A to T, chromosome 9 at 106,515,969 bp (GRCm38)
  • T to A, chromosome 10 at 77,930,555 bp (GRCm38)
  • T to A, chromosome 10 at 78,812,864 bp (GRCm38)
  • T to C, chromosome 10 at 81,535,084 bp (GRCm38)
  • C to G, chromosome 11 at 101,331,088 bp (GRCm38)
  • T to A, chromosome 11 at 110,277,422 bp (GRCm38)
  • T to C, chromosome 13 at 23,034,837 bp (GRCm38)
  • T to A, chromosome 13 at 55,631,857 bp (GRCm38)
  • A to T, chromosome 15 at 36,040,710 bp (GRCm38)
  • G to A, chromosome 15 at 82,081,897 bp (GRCm38)
  • A to T, chromosome 15 at 89,334,500 bp (GRCm38)
  • A to G, chromosome 15 at 91,734,025 bp (GRCm38)
  • C to A, chromosome 17 at 8,951,538 bp (GRCm38)
  • A to G, chromosome 17 at 28,152,440 bp (GRCm38)
  • A to G, chromosome 17 at 56,187,458 bp (GRCm38)
  • A to T, chromosome 17 at 63,499,431 bp (GRCm38)
  • T to A, chromosome 17 at 71,717,370 bp (GRCm38)
  • A to G, chromosome 18 at 67,401,601 bp (GRCm38)
  • C to A, chromosome 18 at 78,109,592 bp (GRCm38)
  • T to A, chromosome 19 at 47,093,752 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9660 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069453-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.