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Strain Name:
C57BL/6J-MtgxR9688Btlr/Mmmh
Stock Number:
069481-MU
Citation ID:
RRID:MMRRC_069481-MU
Other Names:
R9688 (G1)
Major Collection:

Strain Information

Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: roquin, 5730557L09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381305
Homologene: 19036
Gjd2
Name: gap junction protein, delta 2
Synonyms: connexin36, Cx36, Gja9
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14617
Homologene: 7734
Camk1g
Name: calcium/calmodulin-dependent protein kinase I gamma
Synonyms: CLICK-III, CaMKIgamma
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215303
Homologene: 48706
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CS group B correcting gene, CSB, C130058G22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: E230024D05Rik, 9030416H16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71521
Homologene: 22877
Ppfibp2
Name: PTPRF interacting protein, binding protein 2 (liprin beta 2)
Synonyms: liprin beta 2, Cclp1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19024
HGNC: HGNC:9250
Homologene: 7486
Cog6
Name: component of oligomeric golgi complex 6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67542
Homologene: 10802
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Esf1
Name: ESF1 nucleolar pre-rRNA processing protein homolog
Synonyms: 2610101J03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66580
Homologene: 5717
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100019
Homologene: 39689
Jam3
Name: junction adhesion molecule 3
Synonyms: JAM-3, 1110002N23Rik, Jcam3, JAM-C
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83964
Homologene: 11338
Naa16
Name: N(alpha)-acetyltransferase 16, NatA auxiliary subunit
Synonyms: 1300019C06Rik, Narg1l
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66897
Homologene: 134838
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: 4632407J06Rik, 2810487N22Rik, B130055D15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, 8030453L17Rik, E430018P19Rik, KMT2H
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Sgo2a
Name: shugoshin 2A
Synonyms: 5730576N04Rik, Tripin, 1110007N04Rik, D1Ertd8e, Sgol2, Sgol2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68549
Homologene: 51867
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 215113
Homologene: 17555
Ern1
Name: endoplasmic reticulum to nucleus signalling 1
Synonyms: 9030414B18Rik, Ire1alpha, Ire1a, Ire1p
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78943
HGNC: HGNC:3449
Homologene: 55580
Map3k14
Name: mitogen-activated protein kinase kinase kinase 14
Synonyms: Nik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53859
HGNC: HGNC:6853
Homologene: 2940
Cndp1
Name: carnosine dipeptidase 1
Synonyms: Cn1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 338403
Homologene: 57178
Yeats4
Name: YEATS domain containing 4
Synonyms: NuBI-1, 4930573H17Rik, GAS41, B230215M10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64050
VEGA: 10
Homologene: 4760
Zic5
Name: zinc finger protein of the cerebellum 5
Synonyms: odd-paired related, Opr, 1700049L20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 65100
Homologene: 11301
Adarb1
Name: adenosine deaminase, RNA-specific, B1
Synonyms: RED1, ADAR2, D10Bwg0447e, 1700057H01Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110532
HGNC: HGNC:226
Homologene: 8280
Sox6
Name: SRY (sex determining region Y)-box 6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20679
Homologene: 22631
Rhoh
Name: ras homolog family member H
Synonyms: 5830400A04Rik, Arhh
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74734
HGNC: HGNC:686
Homologene: 3180
Ano4
Name: anoctamin 4
Synonyms: A330096O15Rik, Tmem16d
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 320091
Homologene: 66599
Tent4a
Name: terminal nucleotidyltransferase 4A
Synonyms: LAK-1, TRF4, TRF4-1, Pols, Papd7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210106
Homologene: 5089
Sh3rf1
Name: SH3 domain containing ring finger 1
Synonyms: Posh, 2200003J05Rik, Sh3md2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 59009
Homologene: 10988
Tbx15
Name: T-box 15
Synonyms: Tbx8, de, Tbx14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 21384
Homologene: 7967
Pdzd8
Name: PDZ domain containing 8
Synonyms: A630041P07Rik, Pdzk8
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107368
VEGA: 19
Homologene: 14879
Ces2g
Name: carboxylesterase 2G
Synonyms: 2210023G05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72361
HGNC: HGNC:1864
Homologene: 77154
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Klhl5
Name: kelch-like 5
Synonyms: 1300013C10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71778
HGNC: HGNC:6356
Homologene: 56736
L3mbtl1
Name: L3MBTL1 histone methyl-lysine binding protein
Synonyms: L3MBTL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241764
Homologene: 41846
Jag2
Name: jagged 2
Synonyms: Serh, D12Ggc2e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16450
VEGA: 12
HGNC: HGNC:6189
Homologene: 1677
Or6c1b
Name: olfactory receptor family 6 subfamily C member 1B
Synonyms: GA_x6K02T2PULF-11116958-11117896, MOR111-5, Olfr786
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258542
HGNC: HGNC:8355
Homologene: 133582
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Psg23
Name: pregnancy-specific beta-1-glycoprotein 23
Synonyms: 1620401C02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56868
HGNC: HGNC:1819
Homologene: 110989
Abca2
Name: ATP-binding cassette, sub-family A member 2
Synonyms: Abc2, D2H0S1474E
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Hps1
Name: HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
Synonyms: 6030422N11Rik, Hermansky-Pudlak syndrome 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 192236
HGNC: HGNC:5163
Homologene: 163
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: 1110061H03Rik, SRRP129, CASP11, SIP1, 2610510E10Rik, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72193
VEGA: 15
Homologene: 37957
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: 5730527A11Rik, Nhe9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 331004
Homologene: 69753
Antxr1
Name: anthrax toxin receptor 1
Synonyms: 2810405N18Rik, 2310008J16Rik, Tem8
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69538
Homologene: 12976
Elp5
Name: elongator acetyltransferase complex subunit 5
Synonyms: Clone 13u, Rai12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54351
Homologene: 10291
Serinc2
Name: serine incorporator 2
Synonyms: FKSG84, TDE2, 2310004K20Rik, Tde2l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230779
Homologene: 27797
Or5t5
Name: olfactory receptor family 5 subfamily T member 5
Synonyms: GA_x6K02T2Q125-48278396-48279364, MOR179-6, Olfr1093
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258363
Homologene: 133610
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78774
Ms4a5
Name: membrane-spanning 4-domains, subfamily A, member 5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 269063
Homologene: 11404
Terf2
Name: telomeric repeat binding factor 2
Synonyms: TRF2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21750
Homologene: 4133
Vmn1r29
Name: vomeronasal 1 receptor 29
Synonyms: V1rc2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113859
Homologene: 123821
Inca1
Name: inhibitor of CDK, cyclin A1 interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103844
Homologene: 19481
Mtcl3
Name: MTCL family member 3
Synonyms: 6330407J23Rik, Soga3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67412
VEGA: 10
Homologene: 28227
Amz2
Name: archaelysin family metallopeptidase 2
Synonyms: ESTM12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13929
Apobr
Name: apolipoprotein B receptor
Synonyms: Apob-48r, Apob48r
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171504
Homologene: 26695
Zbtb9
Name: zinc finger and BTB domain containing 9
Synonyms: 3930402F13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 474156
Homologene: 45145
Pex12
Name: peroxisomal biogenesis factor 12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103737
HGNC: HGNC:8854
Homologene: 240
1700093K21Rik
Name: RIKEN cDNA 1700093K21 gene
Synonyms: b2b3025Clo
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67358
Homologene: 49849
Yipf4
Name: Yip1 domain family, member 4
Synonyms: 2310034L04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67864
VEGA: 17
Homologene: 32658
Lgalsl
Name: galectin like
Synonyms: 1110067D22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216551
Homologene: 8581
Vmn1r55
Name: vomeronasal 1 receptor 55
Synonyms: LOC236535, LOC384522, V1rd5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384522
Homologene: 41799
Tti2
Name: TELO2 interacting protein 2
Synonyms: BC019943
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234138
Homologene: 11836
Gbx1
Name: gastrulation brain homeobox 1
Synonyms: Gbx-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231044
HGNC: HGNC:4185
Homologene: 41063
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: LOC217602, EG639426, Gm9813, 4921506M07Rik, AU024163
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70846
Homologene: 78002
Pcdhac2
Name: protocadherin alpha subfamily C, 2
Synonyms: CNRc2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 353237
HGNC: HGNC:8677
Homologene: 49562
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 58,017,578 bp (GRCm38)
  • A to G, chromosome 1 at 160,942,664 bp (GRCm38)
  • T to A, chromosome 1 at 193,348,721 bp (GRCm38)
  • G to C, chromosome 2 at 25,434,447 bp (GRCm38)
  • A to T, chromosome 2 at 29,146,316 bp (GRCm38)
  • A to C, chromosome 2 at 86,786,661 bp (GRCm38)
  • A to G, chromosome 2 at 114,011,628 bp (GRCm38)
  • A to T, chromosome 2 at 140,168,175 bp (GRCm38)
  • T to C, chromosome 2 at 146,036,838 bp (GRCm38)
  • A to T, chromosome 2 at 162,948,777 bp (GRCm38)
  • G to T, chromosome 3 at 53,009,107 bp (GRCm38)
  • G to T, chromosome 3 at 55,649,744 bp (GRCm38)
  • T to G, chromosome 3 at 88,984,717 bp (GRCm38)
  • A to T, chromosome 3 at 99,326,392 bp (GRCm38)
  • A to G, chromosome 4 at 32,745,590 bp (GRCm38)
  • C to A, chromosome 4 at 88,676,637 bp (GRCm38)
  • C to A, chromosome 4 at 130,264,340 bp (GRCm38)
  • T to C, chromosome 5 at 24,526,512 bp (GRCm38)
  • T to A, chromosome 5 at 32,897,932 bp (GRCm38)
  • A to T, chromosome 5 at 62,714,766 bp (GRCm38)
  • A to T, chromosome 5 at 65,164,587 bp (GRCm38)
  • A to T, chromosome 5 at 65,654,853 bp (GRCm38)
  • A to G, chromosome 5 at 65,892,313 bp (GRCm38)
  • T to C, chromosome 5 at 137,468,455 bp (GRCm38)
  • A to G, chromosome 6 at 3,377,087 bp (GRCm38)
  • A to T, chromosome 6 at 58,307,754 bp (GRCm38)
  • G to A, chromosome 6 at 87,137,352 bp (GRCm38)
  • G to T, chromosome 7 at 5,146,670 bp (GRCm38)
  • A to T, chromosome 7 at 18,610,622 bp (GRCm38)
  • A to G, chromosome 7 at 107,719,241 bp (GRCm38)
  • G to T, chromosome 7 at 115,476,990 bp (GRCm38)
  • T to C, chromosome 7 at 126,587,491 bp (GRCm38)
  • T to C, chromosome 8 at 31,154,251 bp (GRCm38)
  • T to C, chromosome 8 at 61,226,314 bp (GRCm38)
  • A to T, chromosome 8 at 104,964,672 bp (GRCm38)
  • A to G, chromosome 8 at 107,094,911 bp (GRCm38)
  • A to G, chromosome 9 at 27,056,053 bp (GRCm38)
  • G to A, chromosome 9 at 27,098,908 bp (GRCm38)
  • C to A, chromosome 9 at 95,229,054 bp (GRCm38)
  • T to C, chromosome 10 at 29,196,695 bp (GRCm38)
  • T to A, chromosome 10 at 77,311,265 bp (GRCm38)
  • A to T, chromosome 10 at 89,344,644 bp (GRCm38)
  • T to C, chromosome 10 at 117,215,681 bp (GRCm38)
  • C to A, chromosome 10 at 129,437,098 bp (GRCm38)
  • C to T, chromosome 11 at 20,829,442 bp (GRCm38)
  • A to G, chromosome 11 at 23,519,067 bp (GRCm38)
  • T to A, chromosome 11 at 69,970,599 bp (GRCm38)
  • C to T, chromosome 11 at 70,688,984 bp (GRCm38)
  • T to C, chromosome 11 at 75,543,286 bp (GRCm38)
  • T to C, chromosome 11 at 83,298,431 bp (GRCm38)
  • T to A, chromosome 11 at 102,107,273 bp (GRCm38)
  • T to A, chromosome 11 at 103,239,233 bp (GRCm38)
  • T to C, chromosome 11 at 106,459,010 bp (GRCm38)
  • T to C, chromosome 11 at 109,429,939 bp (GRCm38)
  • T to C, chromosome 11 at 116,234,160 bp (GRCm38)
  • A to T, chromosome 12 at 57,673,816 bp (GRCm38)
  • A to G, chromosome 12 at 112,908,944 bp (GRCm38)
  • A to G, chromosome 13 at 69,507,080 bp (GRCm38)
  • A to C, chromosome 14 at 32,575,798 bp (GRCm38)
  • A to T, chromosome 14 at 79,335,869 bp (GRCm38)
  • T to C, chromosome 14 at 122,464,023 bp (GRCm38)
  • A to C, chromosome 15 at 96,415,927 bp (GRCm38)
  • T to C, chromosome 17 at 26,974,920 bp (GRCm38)
  • A to G, chromosome 17 at 36,548,162 bp (GRCm38)
  • T to A, chromosome 17 at 74,499,083 bp (GRCm38)
  • A to G, chromosome 18 at 37,144,575 bp (GRCm38)
  • G to C, chromosome 18 at 84,637,857 bp (GRCm38)
  • T to C, chromosome 19 at 11,276,694 bp (GRCm38)
  • A to C, chromosome 19 at 42,766,708 bp (GRCm38)
  • G to A, chromosome 19 at 59,345,251 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9688 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069481-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.