Strain Name:
C57BL/6J-MtgxR9698Btlr/Mmmh
Stock Number:
069491-MU
Citation ID:
RRID:MMRRC_069491-MU
Other Names:
R9698 (G1)
Major Collection:

Strain Information

Dhrs3
Name: dehydrogenase/reductase 3
Synonyms: retSDR1, Rsdr1, dehydrogenase/reductase (SDR family) member 3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20148
Homologene: 20994
Anks3
Name: ankyrin repeat and sterile alpha motif domain containing 3
Synonyms: 2700067D09Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72615
VEGA: 16
Homologene: 12475
Pcm1
Name: pericentriolar material 1
Synonyms: 2600002H09Rik, C030044G17Rik, 9430077F19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: 2810449C13Rik, D330022K21Rik, Usp31
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Fmn2
Name: formin 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 54418
Homologene: 137334
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 360013
Homologene: 7977
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: MCPH5, Sha1, Aspm, D330028K02Rik, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Ric8b
Name: RIC8 guanine nucleotide exchange factor B
Synonyms: Ric-8, Ric-8b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237422
VEGA: 10
Homologene: 23080
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Sumf1
Name: sulfatase modifying factor 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58911
Homologene: 16268
Zfp626
Name: zinc finger protein 626
Synonyms: 4933426I21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71163
Ppil4
Name: peptidylprolyl isomerase (cyclophilin)-like 4
Synonyms: 3830425H19Rik, 3732410E19Rik, PPIase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67418
Homologene: 12126
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: LOC381562, A930005E13Rik, D930005K06Rik, Zubr1, p600, 1810009A16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Ten-m3, Odz3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Copg2
Name: coatomer protein complex, subunit gamma 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54160
HGNC: HGNC:2237
Homologene: 56292
Pdlim1
Name: PDZ and LIM domain 1 (elfin)
Synonyms: CLP36, mClim1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54132
HGNC: HGNC:2067
Homologene: 9643
Mfsd14b
Name: major facilitator superfamily domain containing 14B
Synonyms: Hiatl1, 5730414C17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66631
Homologene: 64464
Pot1a
Name: protection of telomeres 1A
Synonyms: Pot1, 1500031H18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101185
Homologene: 32263
Reg3g
Name: regenerating islet-derived 3 gamma
Synonyms: RegIII (gamma)
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19695
Homologene: 128216
Smpd3
Name: sphingomyelin phosphodiesterase 3, neutral
Synonyms: 4631433G07Rik, nSMase2, Nsm2, fro, neutral sphingomyelinase II
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 58994
Homologene: 10260
Hoxa13
Name: homeobox A13
Synonyms: Hox-1.10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15398
HGNC: HGNC:5102
Homologene: 73882
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Il12rb1
Name: interleukin 12 receptor, beta 1
Synonyms: CD212, IL-12R[b]
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16161
HGNC: HGNC:5971
Homologene: 4042
Slc46a2
Name: solute carrier family 46, member 2
Synonyms: 5430429N04Rik, TSO-1C12, Tscot, Ly110
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 30936
Homologene: 23273
Rab11fip4
Name: RAB11 family interacting protein 4 (class II)
Synonyms: A730072L08Rik, RAB11-FIP4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268451
Homologene: 8803
Camk2d
Name: calcium/calmodulin-dependent protein kinase II, delta
Synonyms: 2810011D23Rik, 8030469K03Rik, CaMK II
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 108058
HGNC: HGNC:1462
Homologene: 55561
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241589
Homologene: 115928
Ncdn
Name: neurochondrin
Synonyms: norbin, neurochondrin-2, neurochondrin-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26562
Homologene: 8064
Adamts9
Name: ADAM metallopeptidase with thrombospondin type 1 motif 9
Synonyms: 8430403M15Rik, 1810011L16Rik, UND4, E030027K14Rik, Gsfund3, UND3, Mhdaund3, Mhdaund4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101401
Homologene: 18821
Rmdn2
Name: regulator of microtubule dynamics 2
Synonyms: Fam82a1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381110
VEGA: 17
Homologene: 71930
Abcc9
Name: ATP-binding cassette, sub-family C member 9
Synonyms: SUR2B, Sur2, SUR2A
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Mroh3
Name: maestro heat-like repeat family member 3
Synonyms: 2310006M14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76422
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Or1e30
Name: olfactory receptor family 1 subfamily E member 30
Synonyms: MOR135-26, Olfr390, GA_x6K02T2P1NL-3938806-3939741
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258344
Homologene: 115483
Plxnb1
Name: plexin B1
Synonyms: 2900002G15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235611
HGNC: HGNC:9103
Homologene: 130508
Adprs
Name: ADP-ribosylserine hydrolase
Synonyms: Arh3, Adprhl2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100206
Homologene: 9863
Hrnr
Name: hornerin
Synonyms: S100a18, 1110033K19Rik, A530063N20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68723
Homologene: 138092
Ptpru
Name: protein tyrosine phosphatase receptor type U
Synonyms: RPTPlambda, Ptprl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Cerk
Name: ceramide kinase
Synonyms: D330016D08Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223753
Homologene: 11247
Gpr180
Name: G protein-coupled receptor 180
Synonyms: ITR, E130016I23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 58245
VEGA: 14
Homologene: 32506
Kcna3
Name: potassium voltage-gated channel, shaker-related subfamily, member 3
Synonyms: Mk-3, Kv1.3, Kca1-3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 16491
HGNC: HGNC:6221
Homologene: 128570
Cntn6
Name: contactin 6
Synonyms: NB-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 53870
HGNC: HGNC:2176
Homologene: 8702
Erich2
Name: glutamate rich 2
Synonyms: 4933404M02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66748
Homologene: 75226
Zfpm1
Name: zinc finger protein, multitype 1
Synonyms: Fog1, Friend of GATA-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22761
Homologene: 7606
Tcf23
Name: transcription factor 23
Synonyms: 2010002O16Rik, bHLHa24, Out
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69852
Homologene: 76449
Rassf4
Name: Ras association (RalGDS/AF-6) domain family member 4
Synonyms: 3830411C14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213391
Homologene: 12926
Or55b4
Name: olfactory receptor family 55 subfamily B member 4
Synonyms: GA_x6K02T2PBJ9-5206624-5205620, MOR42-3, Olfr544
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257926
Homologene: 133590
Map10
Name: microtubule-associated protein 10
Synonyms: 4933403G14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74393
Homologene: 10416
Or2m13
Name: olfactory receptor family 2 subfamily M member 13
Synonyms: GA_x54KRFPKG5P-15855164-15854223, MOR279-1, Olfr165
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258458
Homologene: 128262
Hrh3
Name: histamine receptor H3
Synonyms: Eae8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99296
HGNC: HGNC:5184
Homologene: 5232
Tagap1
Name: T cell activation GTPase activating protein 1
Synonyms: 2610315E15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 380608
VEGA: 17
Tdpoz8
Name: TD and POZ domain containing 8
Synonyms: Gm4858
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229571
Homologene: 130121
Mcub
Name: mitochondrial calcium uniporter dominant negative beta subunit
Synonyms: Ccdc109b, 9030408N13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66815
Homologene: 23056
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 136,186,714 bp (GRCm38)
  • T to G, chromosome 1 at 139,461,908 bp (GRCm38)
  • T to A, chromosome 1 at 174,537,173 bp (GRCm38)
  • A to G, chromosome 2 at 70,540,711 bp (GRCm38)
  • A to T, chromosome 2 at 76,943,374 bp (GRCm38)
  • A to G, chromosome 2 at 104,155,051 bp (GRCm38)
  • A to G, chromosome 2 at 180,101,413 bp (GRCm38)
  • T to A, chromosome 3 at 93,074,420 bp (GRCm38)
  • T to C, chromosome 3 at 93,325,787 bp (GRCm38)
  • T to C, chromosome 3 at 107,037,089 bp (GRCm38)
  • C to T, chromosome 3 at 126,840,184 bp (GRCm38)
  • C to T, chromosome 3 at 129,917,019 bp (GRCm38)
  • A to G, chromosome 4 at 59,912,582 bp (GRCm38)
  • T to C, chromosome 4 at 126,316,721 bp (GRCm38)
  • T to C, chromosome 4 at 126,749,895 bp (GRCm38)
  • A to T, chromosome 4 at 131,820,220 bp (GRCm38)
  • T to C, chromosome 4 at 137,633,891 bp (GRCm38)
  • A to G, chromosome 4 at 139,440,664 bp (GRCm38)
  • T to C, chromosome 4 at 144,919,938 bp (GRCm38)
  • C to T, chromosome 5 at 30,968,881 bp (GRCm38)
  • T to C, chromosome 6 at 25,744,616 bp (GRCm38)
  • T to C, chromosome 6 at 30,861,438 bp (GRCm38)
  • T to C, chromosome 6 at 52,259,044 bp (GRCm38)
  • A to C, chromosome 6 at 78,467,822 bp (GRCm38)
  • A to G, chromosome 6 at 92,807,140 bp (GRCm38)
  • T to A, chromosome 6 at 104,833,083 bp (GRCm38)
  • T to C, chromosome 6 at 108,154,962 bp (GRCm38)
  • A to G, chromosome 6 at 116,641,701 bp (GRCm38)
  • T to C, chromosome 6 at 142,626,031 bp (GRCm38)
  • A to G, chromosome 7 at 27,819,015 bp (GRCm38)
  • G to A, chromosome 7 at 44,312,918 bp (GRCm38)
  • G to A, chromosome 7 at 102,484,170 bp (GRCm38)
  • T to C, chromosome 8 at 41,270,504 bp (GRCm38)
  • G to A, chromosome 8 at 48,236,211 bp (GRCm38)
  • G to T, chromosome 8 at 70,811,204 bp (GRCm38)
  • A to T, chromosome 8 at 106,265,664 bp (GRCm38)
  • T to A, chromosome 8 at 122,337,129 bp (GRCm38)
  • T to A, chromosome 8 at 125,671,984 bp (GRCm38)
  • T to A, chromosome 9 at 108,115,971 bp (GRCm38)
  • A to G, chromosome 9 at 109,096,183 bp (GRCm38)
  • A to G, chromosome 10 at 7,807,269 bp (GRCm38)
  • T to C, chromosome 10 at 84,947,497 bp (GRCm38)
  • T to C, chromosome 11 at 73,787,616 bp (GRCm38)
  • A to G, chromosome 11 at 77,829,855 bp (GRCm38)
  • T to A, chromosome 11 at 79,692,766 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • G to A, chromosome 14 at 118,153,890 bp (GRCm38)
  • T to C, chromosome 15 at 86,142,794 bp (GRCm38)
  • T to C, chromosome 16 at 4,948,249 bp (GRCm38)
  • C to A, chromosome 16 at 14,149,213 bp (GRCm38)
  • A to T, chromosome 16 at 19,407,592 bp (GRCm38)
  • C to G, chromosome 17 at 6,961,078 bp (GRCm38)
  • A to G, chromosome 17 at 79,650,300 bp (GRCm38)
  • T to A, chromosome 19 at 40,230,515 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9698 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069491-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.