Strain Name:
C57BL/6J-MtgxR9700Btlr/Mmmh
Stock Number:
069493-MU
Citation ID:
RRID:MMRRC_069493-MU
Other Names:
R9700 (G1)
Major Collection:

Strain Information

Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Zfp809
Name: zinc finger protein 809
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235047
VEGA: 9
Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223666
Homologene: 27825
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Prtg
Name: protogenin
Synonyms: Igdcc5, A230098A12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235472
Homologene: 54453
Dcaf1
Name: DDB1 and CUL4 associated factor 1
Synonyms: Vprbp, B930007L02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 321006
Homologene: 8805
Ints14
Name: integrator complex subunit 14
Synonyms: 2010321M09Rik, Vwa9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69882
VEGA: 9
Homologene: 12774
Faf1
Name: Fas-associated factor 1
Synonyms: Fam, Dffrx
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14084
HGNC: HGNC:3578
Homologene: 5120
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Jam3
Name: junction adhesion molecule 3
Synonyms: Jcam3, JAM-3, JAM-C, 1110002N23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83964
Homologene: 11338
Dhx8
Name: DEAH-box helicase 8
Synonyms: RNA helicase, Ddx8, mDEAH6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217207
HGNC: HGNC:2749
Homologene: 3628
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Myt1
Name: myelin transcription factor 1
Synonyms: NZF-2a, NZF-2b, Nztf2, Nzf2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17932
HGNC: HGNC:7622
Homologene: 3332
Hr
Name: lysine demethylase and nuclear receptor corepressor
Synonyms: N, rh, bldy, rh-bmh, ba
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 15460
HGNC: HGNC:5172
Homologene: 3774
Pum2
Name: pumilio RNA-binding family member 2
Synonyms: Pumm2, 5730503J23Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 80913
Homologene: 69183
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: LOC381562, A930005E13Rik, D930005K06Rik, Zubr1, p600, 1810009A16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Setd1a
Name: SET domain containing 1A
Synonyms: KMT2F
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233904
Homologene: 52251
Vegfa
Name: vascular endothelial growth factor A
Synonyms: VEGF164, VEGF-A, Vegf, VEGF120, VEGF188, VPF
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22339
Homologene: 2534
Rac3
Name: Rac family small GTPase 3
Synonyms: Rac1B
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170758
HGNC: HGNC:9803
Homologene: 68433
Tnc
Name: tenascin C
Synonyms: C130033P17Rik, TN, hexabrachion, Hxb, cytotactin, tenascin-C, TN-C
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Adamts12
Name: ADAM metallopeptidase with thrombospondin type 1 motif 12
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239337
VEGA: 15
Homologene: 12808
Tex30
Name: testis expressed 30
Synonyms: 1700029F09Rik, 3110030D08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75623
Homologene: 16344
Osgin2
Name: oxidative stress induced growth inhibitor family member 2
Synonyms: C230027H09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 209212
HGNC: HGNC:1355
Homologene: 3201
Ddr1
Name: discoidin domain receptor family, member 1
Synonyms: Cak, CD167a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12305
HGNC: HGNC:2730
Homologene: 68212
Aldh1a2
Name: aldehyde dehydrogenase family 1, subfamily A2
Synonyms: Aldh1a7, retinaldehyde dehydrogenase, Raldh2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19378
Homologene: 68368
Tgfbi
Name: transforming growth factor, beta induced
Synonyms: 68kDa, bIG-h3, Beta-ig
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21810
VEGA: 13
Homologene: 37294
Art3
Name: ADP-ribosyltransferase 3
Synonyms: 4930569O04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 109979
HGNC: HGNC:725
Homologene: 911
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Spic
Name: Spi-C transcription factor (Spi-1/PU.1 related)
Synonyms: Spi-C, C76795, Prf
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20728
Homologene: 7953
BC034090
Name: cDNA sequence BC034090
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 207792
Homologene: 19490
AU018091
Name: expressed sequence AU018091
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 245128
Homologene: 106376
Or1j14
Name: olfactory receptor family 1 subfamily J member 14
Synonyms: GA_x6K02T2NLDC-33222024-33222962, MOR136-4, Olfr342
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258950
Homologene: 74223
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22755
Homologene: 117959
Lpin3
Name: lipin 3
Synonyms: 9130206L11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 64899
Homologene: 84844
Ercc6l2
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
Synonyms: 1700019D06Rik, 9330134C04Rik, 0610007P08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76251
Homologene: 32564
Cdc42ep2
Name: CDC42 effector protein 2
Synonyms: Cep2, D19Bwg1013e, Borg1, 1110008C05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104252
VEGA: 19
Homologene: 4933
Mad2l1
Name: MAD2 mitotic arrest deficient-like 1
Synonyms: MAD2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56150
HGNC: HGNC:6763
Homologene: 1768
Or9a2
Name: olfactory receptor family 9 subfamily A member 2
Synonyms: GA_x6K02T2P3E9-5780974-5781915, MOR120-1, Olfr459
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258569
Homologene: 83448
Ninj2
Name: ninjurin 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 29862
HGNC: HGNC:7825
Homologene: 9555
Dpysl5
Name: dihydropyrimidinase-like 5
Synonyms: CRAM, Crmp5, CRMP-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 65254
Homologene: 41347
Or14a256
Name: olfactory receptor family 14 subfamily A member 256
Synonyms: GA_x6K02T2NHDJ-9504525-9505532, MOR219-5, Olfr294
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257904
Zfp36l2
Name: zinc finger protein 36, C3H type-like 2
Synonyms: Tis11d, ERF2, Brf2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12193
HGNC: HGNC:1108
Homologene: 5027
Polh
Name: polymerase (DNA directed), eta (RAD 30 related)
Synonyms: RAD30A
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 80905
VEGA: 17
HGNC: HGNC:9181
Homologene: 38189
C2cd6
Name: C2 calcium dependent domain containing 6
Synonyms: 1700052H20Rik, C2cd6b, Gm33589, Als2cr11, 4930408G06Rik, Als2cr11b
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73463
Homologene: 134310
Or6b9
Name: olfactory receptor family 6 subfamily B member 9
Synonyms: M50, GA_x6K02T2PBJ9-9337331-9336381, Olfr6, MOR103-16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233670
Homologene: 28439
Arpin
Name: actin-related protein 2/3 complex inhibitor
Synonyms: 2610034B18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70420
Homologene: 128480
Six2
Name: sine oculis-related homeobox 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20472
Homologene: 56518
Pcdha5
Name: protocadherin alpha 5
Synonyms: Crnr6, Cnr6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12941
HGNC: HGNC:8671
Homologene: 49565
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 44,091,214 bp (GRCm38)
  • T to G, chromosome 1 at 59,077,930 bp (GRCm38)
  • C to T, chromosome 1 at 155,226,236 bp (GRCm38)
  • T to A, chromosome 2 at 36,528,301 bp (GRCm38)
  • A to T, chromosome 2 at 160,898,645 bp (GRCm38)
  • A to G, chromosome 2 at 181,810,384 bp (GRCm38)
  • A to G, chromosome 4 at 16,006,455 bp (GRCm38)
  • A to G, chromosome 4 at 64,014,949 bp (GRCm38)
  • A to G, chromosome 4 at 109,890,982 bp (GRCm38)
  • T to A, chromosome 4 at 139,392,077 bp (GRCm38)
  • C to T, chromosome 5 at 30,747,073 bp (GRCm38)
  • T to G, chromosome 5 at 92,414,261 bp (GRCm38)
  • T to C, chromosome 5 at 137,456,574 bp (GRCm38)
  • T to C, chromosome 6 at 18,268,360 bp (GRCm38)
  • T to A, chromosome 6 at 41,772,142 bp (GRCm38)
  • C to A, chromosome 6 at 66,535,971 bp (GRCm38)
  • T to C, chromosome 6 at 120,197,912 bp (GRCm38)
  • A to T, chromosome 7 at 3,158,325 bp (GRCm38)
  • G to A, chromosome 7 at 24,275,469 bp (GRCm38)
  • A to G, chromosome 7 at 79,928,267 bp (GRCm38)
  • A to T, chromosome 7 at 86,616,410 bp (GRCm38)
  • A to G, chromosome 7 at 106,956,423 bp (GRCm38)
  • A to T, chromosome 7 at 127,786,580 bp (GRCm38)
  • A to G, chromosome 8 at 85,841,067 bp (GRCm38)
  • T to C, chromosome 9 at 22,243,174 bp (GRCm38)
  • T to C, chromosome 9 at 27,098,887 bp (GRCm38)
  • C to T, chromosome 9 at 64,972,725 bp (GRCm38)
  • G to T, chromosome 9 at 71,215,946 bp (GRCm38)
  • A to G, chromosome 9 at 72,855,031 bp (GRCm38)
  • C to T, chromosome 9 at 106,858,325 bp (GRCm38)
  • T to C, chromosome 10 at 28,580,499 bp (GRCm38)
  • T to A, chromosome 10 at 88,679,895 bp (GRCm38)
  • G to A, chromosome 11 at 101,733,189 bp (GRCm38)
  • A to T, chromosome 11 at 120,722,573 bp (GRCm38)
  • T to C, chromosome 12 at 8,729,044 bp (GRCm38)
  • T to C, chromosome 13 at 56,630,598 bp (GRCm38)
  • A to G, chromosome 13 at 63,819,711 bp (GRCm38)
  • T to C, chromosome 14 at 70,567,176 bp (GRCm38)
  • C to T, chromosome 15 at 11,311,356 bp (GRCm38)
  • T to C, chromosome 15 at 76,727,417 bp (GRCm38)
  • A to T, chromosome 17 at 35,682,396 bp (GRCm38)
  • G to A, chromosome 17 at 46,031,787 bp (GRCm38)
  • A to T, chromosome 17 at 46,199,488 bp (GRCm38)
  • A to G, chromosome 17 at 84,186,756 bp (GRCm38)
  • A to G, chromosome 17 at 85,687,439 bp (GRCm38)
  • A to G, chromosome 18 at 36,961,394 bp (GRCm38)
  • T to C, chromosome 19 at 5,918,069 bp (GRCm38)
  • T to C, chromosome 19 at 24,304,096 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9700 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069493-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.