Strain Name:
C57BL/6J-MtgxR9701Btlr/Mmmh
Stock Number:
069494-MU
Citation ID:
RRID:MMRRC_069494-MU
Other Names:
R9701 (G1)
Major Collection:

Strain Information

Ap4e1
Name: adaptor-related protein complex AP-4, epsilon 1
Synonyms: 2310033A20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 108011
HGNC: HGNC:573
Homologene: 22397
Slc6a6
Name: solute carrier family 6 (neurotransmitter transporter, taurine), member 6
Synonyms: Taut
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21366
Homologene: 2291
Lhx5
Name: LIM homeobox protein 5
Synonyms: Lim2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16873
Homologene: 40621
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: D630035I23Rik, TRIP8, 5430433L24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Cwf19l2
Name: CWF19 like cell cycle control factor 2
Synonyms: 3230401L03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244672
Homologene: 12366
Egr1
Name: early growth response 1
Synonyms: Krox-1, Krox-24, ETR103, NGF1-A, A530045N19Rik, Zfp-6, Krox24, Zenk, Zif268, Egr-1, NGFI-A, NGFIA, TIS8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13653
HGNC: HGNC:3238
Homologene: 56394
Abcc8
Name: ATP-binding cassette, sub-family C member 8
Synonyms: SUR1, D930031B21Rik, Sur
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Dock9
Name: dedicator of cytokinesis 9
Synonyms: Zizimin1, D14Wsu89e, B230309H04Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105445
Homologene: 41026
Mib1
Name: MIB E3 ubiquitin protein ligase 1
Synonyms: E430019M12Rik, mindbomb, skeletrophin, Mib, mind bomb-1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225164
Homologene: 10810
Sec24d
Name: SEC24 homolog D, COPII coat complex component
Synonyms: 2310020L09Rik, LOC383951
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69608
Homologene: 40986
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: ASTBDN, tubedown, Tbdn-1, mNAT1, 5730450D16Rik, Narg1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74838
Homologene: 14211
Prkab1
Name: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Synonyms: 1300015D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19079
HGNC: HGNC:9378
Homologene: 38160
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20286
VEGA: 15
Homologene: 9735
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213895
Homologene: 7065
Srbd1
Name: S1 RNA binding domain 1
Synonyms: D530025C17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78586
VEGA: 17
Homologene: 9994
Bltp3b
Name: bridge-like lipid transfer protein family member 3B
Synonyms: 4930506D01Rik, E030041M21Rik, Uhrf1bp1l, 2010319N22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75089
VEGA: 10
Homologene: 12590
Cux1
Name: cut-like homeobox 1
Synonyms: Cux-1, Cux, CDP, Cutl1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13047
HGNC: HGNC:2557
Hspa5
Name: heat shock protein 5
Synonyms: baffled, D2Wsu141e, Grp78, D2Wsu17e, Hsce70, mBiP, Bip, XAP-1 antigen, 78kDa, Sez7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14828
HGNC: HGNC:5238
Homologene: 3908
Gnpat
Name: glyceronephosphate O-acyltransferase
Synonyms: D1Ertd819e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14712
HGNC: HGNC:4416
Homologene: 40716
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 21819
Homologene: 2430
Ubtf
Name: upstream binding transcription factor, RNA polymerase I
Synonyms: A930005G04Rik, UBF1, UBF, Tcfubf
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21429
Homologene: 7970
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67534
Homologene: 8764
Thbs1
Name: thrombospondin 1
Synonyms: TSP1, tbsp1, Thbs-1, TSP-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21825
Homologene: 31142
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Dock7
Name: dedicator of cytokinesis 7
Synonyms: LOC242555, 3110056M06Rik, m
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67299
Homologene: 23566
Vegfa
Name: vascular endothelial growth factor A
Synonyms: VPF, VEGF120, VEGF-A, Vegf, VEGF164, VEGF188
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22339
Homologene: 2534
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: 2900010L19Rik, mSorLA, LR11, Sorla
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20660
Homologene: 2336
Nxf1
Name: nuclear RNA export factor 1
Synonyms: Tip associated protein, Mvb1, Mex67, TAP
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 53319
HGNC: HGNC:8071
Homologene: 38176
Inpp5f
Name: inositol polyphosphate-5-phosphatase F
Synonyms: SAC2, 5830435P03Rik, cI-27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101490
Homologene: 8962
Alg8
Name: ALG8 alpha-1,3-glucosyltransferase
Synonyms: LOC381903
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381903
Homologene: 6931
Nup153
Name: nucleoporin 153
Synonyms: B130015D15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218210
HGNC: HGNC:8062
Homologene: 68442
Map1s
Name: microtubule-associated protein 1S
Synonyms: VCY2IP1, Mtap1s, Bpy2ip1, Map8, 6430517J16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270058
Homologene: 10047
Dclk3
Name: doublecortin-like kinase 3
Synonyms: Click-I, -II related, Dcamkl3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245038
Homologene: 70580
Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
Synonyms: ECaC1, CaT2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194352
HGNC: HGNC:3145
Homologene: 10520
Rnf212
Name: ring finger protein 212
Synonyms: EG330157, repro57
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 671564
Homologene: 131269
Sall3
Name: spalt like transcription factor 3
Synonyms: Msal, Msal-1, B130022O04Rik, Spalt, Salt
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20689
VEGA: 18
Homologene: 18142
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Cpfl8, dice, 6820443O06Rik, nesprin-2, syne-2, Nesp2g, diminished cone electroretinogram
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Ptprd
Name: protein tyrosine phosphatase receptor type D
Synonyms: B230219D21Rik, 1110002J03Rik, 3000002J10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Urod
Name: uroporphyrinogen decarboxylase
Synonyms: Uro-d
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22275
Homologene: 320
Nlrp1a
Name: NLR family, pyrin domain containing 1A
Synonyms: Nalp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195046
Homologene: 133820
Gzmn
Name: granzyme N
Synonyms: GrN
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 245839
VEGA: 14
HGNC: HGNC:4709
Homologene: 87221
Eln
Name: elastin
Synonyms: tropoelastin, E030024M20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13717
HGNC: HGNC:3327
Treh
Name: trehalase (brush-border membrane glycoprotein)
Synonyms: 2210412M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 58866
Homologene: 5198
Skint3
Name: selection and upkeep of intraepithelial T cells 3
Synonyms: A430090E18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 195564
Tshz1
Name: teashirt zinc finger family member 1
Synonyms: 5730407I04Rik, D18Bwg1409e, Mtsh1, Tsh1, Sdccag33, NY-CO-33, teashirt1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 110796
Homologene: 4227
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Gm973
Name: predicted gene 973
Synonyms: LOC381260
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381260
Homologene: 124277
Slc6a20a
Name: solute carrier family 6 (neurotransmitter transporter), member 20A
Synonyms: A730081N20Rik, Xtrp3s1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102680
Homologene: 10625
Armc12
Name: armadillo repeat containing 12
Synonyms: 4930511I11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67645
Homologene: 12168
Dyrk1b
Name: dual-specificity tyrosine phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
Rbm12
Name: RNA binding motif protein 12
Synonyms: SWAN, 5730420G12Rik, 9430070C08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75710
HGNC: HGNC:9898
Homologene: 34993
Gpr180
Name: G protein-coupled receptor 180
Synonyms: ITR, E130016I23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 58245
VEGA: 14
Homologene: 32506
Plekhg6
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Synonyms: LOC213522
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213522
Homologene: 32395
Hcfc2
Name: host cell factor C2
Synonyms: 1700129L13Rik, fkls
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67933
Homologene: 8337
Mrpl9
Name: mitochondrial ribosomal protein L9
Synonyms: 8030480E20Rik, C330013D18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 78523
Homologene: 12696
Or13j1
Name: olfactory receptor family 13 subfamily J member 1
Synonyms: mOR17, Olfr71, MOR262-4, GA_x6K02T2N78B-16230286-16231224
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56015
Homologene: 10460
Gpx6
Name: glutathione peroxidase 6
Synonyms: 1700020G18Rik, olfactory
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75512
HGNC: HGNC:4558
Homologene: 130008
Igkv3-10
Name: immunoglobulin kappa variable 3-10
Synonyms: V-kappa-21B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667924
Mutyh
Name: mutY DNA glycosylase
Synonyms: Mutyhalpha, 5730495A01Rik, Mutyhbeta, Mutyhb, Mutyhc, Mutyha, Myh
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70603
HGNC: HGNC:7527
Homologene: 8156
Mrgpra6
Name: MAS-related GPR, member A6
Synonyms: MrgA6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381886
Serpina16
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16
Synonyms: Gm46, LOC194604
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 194604
Homologene: 52303
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 53,522,229 bp (GRCm38)
  • T to A, chromosome 1 at 59,526,873 bp (GRCm38)
  • A to G, chromosome 1 at 74,681,323 bp (GRCm38)
  • C to T, chromosome 2 at 34,774,637 bp (GRCm38)
  • G to T, chromosome 2 at 76,918,583 bp (GRCm38)
  • A to G, chromosome 2 at 118,120,235 bp (GRCm38)
  • T to C, chromosome 2 at 127,033,643 bp (GRCm38)
  • A to G, chromosome 2 at 156,096,246 bp (GRCm38)
  • T to A, chromosome 3 at 51,441,949 bp (GRCm38)
  • A to G, chromosome 3 at 94,444,585 bp (GRCm38)
  • T to C, chromosome 3 at 123,269,672 bp (GRCm38)
  • C to A, chromosome 4 at 43,705,793 bp (GRCm38)
  • A to G, chromosome 4 at 75,998,659 bp (GRCm38)
  • T to C, chromosome 4 at 98,958,147 bp (GRCm38)
  • T to A, chromosome 4 at 112,253,897 bp (GRCm38)
  • A to G, chromosome 4 at 116,819,288 bp (GRCm38)
  • C to T, chromosome 4 at 116,992,581 bp (GRCm38)
  • A to G, chromosome 5 at 108,774,872 bp (GRCm38)
  • T to C, chromosome 5 at 116,024,215 bp (GRCm38)
  • T to A, chromosome 5 at 120,434,598 bp (GRCm38)
  • C to A, chromosome 5 at 134,715,705 bp (GRCm38)
  • T to C, chromosome 5 at 136,314,315 bp (GRCm38)
  • G to T, chromosome 6 at 41,674,660 bp (GRCm38)
  • T to C, chromosome 6 at 70,573,017 bp (GRCm38)
  • T to C, chromosome 6 at 91,723,497 bp (GRCm38)
  • T to A, chromosome 6 at 118,391,186 bp (GRCm38)
  • C to T, chromosome 6 at 125,370,639 bp (GRCm38)
  • G to A, chromosome 7 at 28,186,413 bp (GRCm38)
  • G to A, chromosome 7 at 44,312,918 bp (GRCm38)
  • T to C, chromosome 7 at 46,136,630 bp (GRCm38)
  • C to T, chromosome 7 at 47,185,785 bp (GRCm38)
  • T to A, chromosome 7 at 97,378,279 bp (GRCm38)
  • A to C, chromosome 7 at 128,676,791 bp (GRCm38)
  • A to G, chromosome 8 at 11,443,104 bp (GRCm38)
  • C to T, chromosome 8 at 70,917,068 bp (GRCm38)
  • A to G, chromosome 8 at 124,886,939 bp (GRCm38)
  • A to T, chromosome 9 at 3,430,454 bp (GRCm38)
  • A to G, chromosome 9 at 42,092,470 bp (GRCm38)
  • A to G, chromosome 9 at 44,683,351 bp (GRCm38)
  • A to G, chromosome 9 at 111,469,176 bp (GRCm38)
  • T to A, chromosome 9 at 123,660,520 bp (GRCm38)
  • A to T, chromosome 10 at 67,224,966 bp (GRCm38)
  • G to T, chromosome 10 at 82,738,435 bp (GRCm38)
  • G to A, chromosome 10 at 89,779,893 bp (GRCm38)
  • T to C, chromosome 11 at 71,097,120 bp (GRCm38)
  • A to G, chromosome 11 at 102,308,892 bp (GRCm38)
  • A to G, chromosome 12 at 75,990,423 bp (GRCm38)
  • T to C, chromosome 12 at 103,672,614 bp (GRCm38)
  • A to T, chromosome 13 at 21,317,607 bp (GRCm38)
  • A to T, chromosome 13 at 46,686,735 bp (GRCm38)
  • T to C, chromosome 14 at 56,167,853 bp (GRCm38)
  • G to A, chromosome 14 at 118,153,890 bp (GRCm38)
  • A to T, chromosome 14 at 121,639,571 bp (GRCm38)
  • C to G, chromosome 15 at 66,766,142 bp (GRCm38)
  • C to T, chromosome 15 at 81,792,304 bp (GRCm38)
  • A to T, chromosome 17 at 28,532,401 bp (GRCm38)
  • G to A, chromosome 17 at 46,031,787 bp (GRCm38)
  • T to C, chromosome 17 at 86,126,131 bp (GRCm38)
  • T to A, chromosome 18 at 10,798,494 bp (GRCm38)
  • T to C, chromosome 18 at 34,862,621 bp (GRCm38)
  • C to A, chromosome 18 at 80,974,228 bp (GRCm38)
  • A to G, chromosome 18 at 84,014,454 bp (GRCm38)
  • G to A, chromosome 19 at 8,762,408 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9701 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069494-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.