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Strain Name:
C57BL/6J-MtgxR9734Btlr/Mmmh
Stock Number:
069980-MU
Citation ID:
RRID:MMRRC_069980-MU
Other Names:
R9734 (G1)
Major Collection:

Strain Information

Bri3bp
Name: Bri3 binding protein
Synonyms: 2410150I18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76809
Homologene: 50955
Acot7
Name: acyl-CoA thioesterase 7
Synonyms: 2410041A17Rik, Bach, AU014716
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70025
Homologene: 15780
Scamp2
Name: secretory carrier membrane protein 2
Synonyms: Sc2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24044
VEGA: 9
Homologene: 4163
Akap12
Name: A kinase anchor protein 12
Synonyms: SSeCKS, Tsga12, Srcs5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 83397
VEGA: 10
HGNC: HGNC:370
Homologene: 3740
Lamb2
Name: laminin, beta 2
Synonyms: Lamb-2, Lams, npht
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665775
Homologene: 45109
Bnip3l
Name: BCL2/adenovirus E1B interacting protein 3-like
Synonyms: Nix, D14Ertd719e, Nip3L
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12177
HGNC: HGNC:1085
Homologene: 3195
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 74,415,150 bp (GRCm38)
  • T to A, chromosome 2 at 118,240,435 bp (GRCm38)
  • A to G, chromosome 2 at 125,389,978 bp (GRCm38)
  • T to A, chromosome 2 at 156,338,620 bp (GRCm38)
  • A to T, chromosome 3 at 89,089,189 bp (GRCm38)
  • T to C, chromosome 3 at 116,546,055 bp (GRCm38)
  • A to G, chromosome 4 at 134,074,651 bp (GRCm38)
  • A to G, chromosome 4 at 144,331,167 bp (GRCm38)
  • T to A, chromosome 4 at 152,261,017 bp (GRCm38)
  • A to T, chromosome 5 at 41,805,230 bp (GRCm38)
  • T to A, chromosome 5 at 69,569,262 bp (GRCm38)
  • G to T, chromosome 5 at 125,441,672 bp (GRCm38)
  • G to T, chromosome 5 at 140,692,809 bp (GRCm38)
  • G to C, chromosome 6 at 87,111,857 bp (GRCm38)
  • A to G, chromosome 7 at 7,231,493 bp (GRCm38)
  • A to G, chromosome 7 at 56,985,160 bp (GRCm38)
  • T to A, chromosome 7 at 85,233,549 bp (GRCm38)
  • A to G, chromosome 7 at 102,415,353 bp (GRCm38)
  • A to G, chromosome 8 at 94,568,600 bp (GRCm38)
  • A to T, chromosome 9 at 38,672,943 bp (GRCm38)
  • T to C, chromosome 9 at 39,646,906 bp (GRCm38)
  • T to G, chromosome 9 at 57,582,892 bp (GRCm38)
  • G to T, chromosome 9 at 108,488,631 bp (GRCm38)
  • C to T, chromosome 10 at 4,355,929 bp (GRCm38)
  • T to A, chromosome 13 at 23,136,864 bp (GRCm38)
  • A to G, chromosome 13 at 99,228,844 bp (GRCm38)
  • C to A, chromosome 14 at 35,580,785 bp (GRCm38)
  • G to A, chromosome 14 at 67,008,765 bp (GRCm38)
  • C to T, chromosome 17 at 23,631,860 bp (GRCm38)
  • T to A, chromosome 17 at 35,638,341 bp (GRCm38)
  • T to C, chromosome 17 at 43,452,308 bp (GRCm38)
  • A to T, chromosome 18 at 12,549,263 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9734 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069980-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.