Strain Name:
C57BL/6J-MtgxR9737Btlr/Mmmh
Stock Number:
069983-MU
Citation ID:
RRID:MMRRC_069983-MU
Other Names:
R9737 (G1)
Major Collection:

Strain Information

Epha2
Name: Eph receptor A2
Synonyms: Myk2, Eck, Sek2, Sek-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13836
HGNC: HGNC:3386
Homologene: 20929
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: Cream1, BEN, GTF3, MusTRD1, ESTM9, binding factor for early enhancer, WBSCR11
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 57080
HGNC: HGNC:4661
Homologene: 4158
Ngdn
Name: neuroguidin, EIF4E binding protein
Synonyms: Ngd, 1500001L15Rik, neuroguidin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68966
VEGA: 14
Homologene: 44286
Adnp
Name: activity-dependent neuroprotective protein
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11538
Homologene: 7617
Zkscan5
Name: zinc finger with KRAB and SCAN domains 5
Synonyms: hKraba1, Zfp95
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22757
Homologene: 8734
Bnip3l
Name: BCL2/adenovirus E1B interacting protein 3-like
Synonyms: Nix, D14Ertd719e, Nip3L
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12177
HGNC: HGNC:1085
Homologene: 3195
Pkd2
Name: polycystin 2, transient receptor potential cation channel
Synonyms: TRPP2, PC2, polycystin-2, C030034P18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18764
HGNC: HGNC:9009
Homologene: 20104
Pou6f1
Name: POU domain, class 6, transcription factor 1
Synonyms: Emb, 2310038G18Rik, cns-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19009
HGNC: HGNC:9224
Homologene: 7703
Phlpp2
Name: PH domain and leucine rich repeat protein phosphatase 2
Synonyms: Phlppl, C130044A18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244650
Homologene: 71015
Cfhr4
Name: complement factor H-related 4
Synonyms: Gm4788
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214403
HGNC: HGNC:4883
Vmn2r99
Name: vomeronasal 2, receptor 99
Synonyms: EG665376
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665376
Homologene: 115024
Sidt1
Name: SID1 transmembrane family, member 1
Synonyms: B830021E24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320007
Homologene: 41189
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52372
Vnn3
Name: vanin 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 26464
Homologene: 48295
Pabpc4l
Name: poly(A) binding protein, cytoplasmic 4-like
Synonyms: C330050A14Rik, EG241989
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241989
Homologene: 66336
Jhy
Name: junctional cadherin complex regulator
Synonyms: 4931429I11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70989
Homologene: 11726
Ccnjl
Name: cyclin J-like
Synonyms: LOC380694
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380694
Homologene: 11588
Igkv10-96
Name: immunoglobulin kappa variable 10-96
Synonyms: Gm16637
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 692165
Trav13-1
Name: T cell receptor alpha variable 13-1
Synonyms: Gm16980
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100126469
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 139,781,134 bp (GRCm38)
  • T to C, chromosome 2 at 168,184,998 bp (GRCm38)
  • A to G, chromosome 3 at 46,446,832 bp (GRCm38)
  • A to G, chromosome 4 at 141,318,503 bp (GRCm38)
  • A to T, chromosome 5 at 104,503,483 bp (GRCm38)
  • A to G, chromosome 5 at 134,379,940 bp (GRCm38)
  • A to G, chromosome 5 at 145,205,326 bp (GRCm38)
  • T to C, chromosome 6 at 68,631,973 bp (GRCm38)
  • G to C, chromosome 6 at 87,111,857 bp (GRCm38)
  • G to A, chromosome 8 at 109,937,082 bp (GRCm38)
  • T to C, chromosome 9 at 40,897,452 bp (GRCm38)
  • A to G, chromosome 10 at 23,865,915 bp (GRCm38)
  • C to A, chromosome 11 at 43,585,339 bp (GRCm38)
  • A to T, chromosome 14 at 53,545,053 bp (GRCm38)
  • A to G, chromosome 14 at 55,021,882 bp (GRCm38)
  • G to A, chromosome 14 at 67,008,765 bp (GRCm38)
  • A to G, chromosome 15 at 100,583,401 bp (GRCm38)
  • A to G, chromosome 16 at 44,281,880 bp (GRCm38)
  • A to C, chromosome 17 at 19,362,301 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9737 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069983-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.