Strain Name:
C57BL/6J-MtgxR9739Btlr/Mmmh
Stock Number:
069985-MU
Citation ID:
RRID:MMRRC_069985-MU
Other Names:
R9739 (G1)
Major Collection:

Strain Information

Ctnnal1
Name: catenin alpha like 1
Synonyms: catenin (cadherin associated protein), alpha-like 1, Catnal1, ACRP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 328977
Homologene: 138627
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, RA-GEF-2, C030018K18Rik, Pdzgef2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Fkbp4
Name: FK506 binding protein 4
Synonyms: FKBP52, FKBP-52
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14228
HGNC: HGNC:3720
Homologene: 36085
Bend3
Name: BEN domain containing 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 331623
VEGA: 10
Homologene: 19511
Syngr2
Name: synaptogyrin 2
Synonyms: cellugyrin, Clast2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20973
Homologene: 20987
Sfrp5
Name: secreted frizzled-related sequence protein 5
Synonyms: SARP3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54612
Homologene: 2268
Thap1
Name: THAP domain containing, apoptosis associated protein 1
Synonyms: 4833431A01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73754
Homologene: 10005
Bach2
Name: BTB and CNC homology, basic leucine zipper transcription factor 2
Synonyms: E030004N02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12014
Homologene: 7240
Esco1
Name: establishment of sister chromatid cohesion N-acetyltransferase 1
Synonyms: A930014I12Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 77805
Homologene: 62166
Tubgcp3
Name: tubulin, gamma complex component 3
Synonyms: GCP3, Spc98p
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 259279
Homologene: 4609
Pde12
Name: phosphodiesterase 12
Synonyms: E430028B21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 211948
Homologene: 14272
Fyb1
Name: FYN binding protein 1
Synonyms: FYB-120/130, ADAP, B630013F22Rik, Fyb
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 23880
HGNC: HGNC:4036
Homologene: 22664
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: Bai3, A830096D10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Ccdc175
Name: coiled-coil domain containing 175
Synonyms: 4930403N07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73936
VEGA: 12
Homologene: 79144
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234686
Homologene: 136406
Scyl3
Name: SCY1-like 3 (S. cerevisiae)
Synonyms: Pace1, 1200016D23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240880
Homologene: 10706
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Casq1
Name: calsequestrin 1
Synonyms: CSQ1, sCSQ, CSQ-1, CSQ
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12372
HGNC: HGNC:1512
Homologene: 20329
Pfkfb2
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Synonyms: 4930568D07Rik, PFK-2/FBPase-2 gene B
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18640
HGNC: HGNC:8873
Homologene: 88554
Or8g21
Name: olfactory receptor family 8 subfamily G member 21
Synonyms: GA_x6K02T2PVTD-32691280-32690354, MOR171-11, Olfr935
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258741
VEGA: 9
Homologene: 133683
Or9s18
Name: olfactory receptor family 9 subfamily S member 18
Synonyms: Olfr466, GA_x6K02T2PB7A-3051266-3052192, MOR209-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258816
Homologene: 72032
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Plcd1
Name: phospholipase C, delta 1
Synonyms: PLC-delta 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18799
VEGA: 9
HGNC: HGNC:9060
Homologene: 21252
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54667
Homologene: 23226
Alg6
Name: ALG6 alpha-1,3-glucosyltransferase
Synonyms: E230028F23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320438
Homologene: 6920
Cd200r4
Name: CD200 receptor 4
Synonyms: F630107N04Rik, MCD200RLa
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239849
Homologene: 45557
Gm17019
Name: predicted gene 17019
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66773
Homologene: 69402
Snrpf
Name: small nuclear ribonucleoprotein polypeptide F
Synonyms: 2010013O18Rik, SMF
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 69878
Homologene: 130366
Gm37240
Name: predicted gene, 37240
Type: Gene
Species: Mouse
Chromosome: 3
Gm9195
Name: predicted gene 9195
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 675947
Homologene: 139067
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 20,350,484 bp (GRCm38)
  • C to T, chromosome 1 at 25,553,768 bp (GRCm38)
  • T to C, chromosome 1 at 130,697,078 bp (GRCm38)
  • T to C, chromosome 1 at 163,943,850 bp (GRCm38)
  • T to C, chromosome 1 at 172,215,484 bp (GRCm38)
  • T to C, chromosome 2 at 82,993,552 bp (GRCm38)
  • A to G, chromosome 3 at 84,509,806 bp (GRCm38)
  • A to G, chromosome 3 at 89,946,096 bp (GRCm38)
  • T to A, chromosome 4 at 32,563,042 bp (GRCm38)
  • T to C, chromosome 4 at 56,816,200 bp (GRCm38)
  • G to A, chromosome 4 at 99,761,958 bp (GRCm38)
  • T to A, chromosome 4 at 143,728,427 bp (GRCm38)
  • G to A, chromosome 5 at 15,032,827 bp (GRCm38)
  • T to C, chromosome 6 at 128,433,765 bp (GRCm38)
  • A to T, chromosome 7 at 104,861,529 bp (GRCm38)
  • A to G, chromosome 8 at 12,649,744 bp (GRCm38)
  • C to T, chromosome 8 at 26,160,962 bp (GRCm38)
  • C to T, chromosome 8 at 105,337,746 bp (GRCm38)
  • G to T, chromosome 9 at 38,995,006 bp (GRCm38)
  • A to G, chromosome 9 at 119,072,127 bp (GRCm38)
  • T to C, chromosome 10 at 43,509,851 bp (GRCm38)
  • C to T, chromosome 10 at 93,583,528 bp (GRCm38)
  • A to G, chromosome 11 at 54,622,363 bp (GRCm38)
  • T to A, chromosome 11 at 117,812,472 bp (GRCm38)
  • A to T, chromosome 12 at 72,140,018 bp (GRCm38)
  • T to C, chromosome 13 at 65,152,628 bp (GRCm38)
  • A to T, chromosome 14 at 7,935,954 bp (GRCm38)
  • T to C, chromosome 14 at 26,665,602 bp (GRCm38)
  • C to T, chromosome 14 at 72,452,824 bp (GRCm38)
  • A to G, chromosome 14 at 103,282,793 bp (GRCm38)
  • A to G, chromosome 15 at 6,640,582 bp (GRCm38)
  • A to T, chromosome 16 at 44,820,779 bp (GRCm38)
  • T to A, chromosome 18 at 10,594,218 bp (GRCm38)
  • T to C, chromosome 18 at 24,770,509 bp (GRCm38)
  • C to T, chromosome 18 at 65,624,823 bp (GRCm38)
  • T to A, chromosome 19 at 42,199,808 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9739 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069985-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.