Strain Name:
C57BL/6J-MtgxR9744Btlr/Mmmh
Stock Number:
069990-MU
Citation ID:
RRID:MMRRC_069990-MU
Other Names:
R9744 (G1)
Major Collection:

Strain Information

Pitx2
Name: paired-like homeodomain transcription factor 2
Synonyms: Ptx2, Otlx2, Rieg, Pitx2c, Pitx2b, Pitx2a, solurshin, Brx1, Brx1a, Munc30, Brx1b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18741
HGNC: HGNC:9005
Homologene: 55454
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103554
Homologene: 113742
Cep41
Name: centrosomal protein 41
Synonyms: 1700017E11Rik, 2810431D15Rik, Cep41, Tsga14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 83922
Homologene: 10284
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229543
Homologene: 11309
Prrc2c
Name: proline-rich coiled-coil 2C
Synonyms: Bat2l2, 9630039I18Rik, 1810043M20Rik, Bat2d
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226562
Homologene: 41015
Nup205
Name: nucleoporin 205
Synonyms: 3830404O05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70699
Homologene: 45971
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, Fndc3, D14Ertd453e, sys
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Polr1a
Name: polymerase (RNA) I polypeptide A
Synonyms: Rpo1-4, 3010014K16Rik, RPA194, 194kDa, mRPA1, 2900087K15Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20019
Homologene: 7033
Mdn1
Name: midasin AAA ATPase 1
Synonyms: 4833432B22Rik, LOC213784, D4Abb1e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100019
Homologene: 39689
Epha8
Name: Eph receptor A8
Synonyms: EphA8, Hek3, Eek
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Dmbx1
Name: diencephalon/mesencephalon homeobox 1
Synonyms: Dmbx1, Cdmx, Mbx, Atx, Otx3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 140477
Homologene: 15639
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: enaptin165, nesprin-1, A330049M09Rik, C130039F11Rik, SYNE-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Erc1
Name: ELKS/RAB6-interacting/CAST family member 1
Synonyms: RAB6IP2B, RAB6IP2A, Rab6ip2, 9630025C19Rik, 5033405M01Rik, Elks1, B430107L16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 111173
Homologene: 14229
Itih5
Name: inter-alpha-trypsin inhibitor, heavy chain 5
Synonyms: 5430408M01Rik, 4631408O11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209378
Homologene: 57115
Tob1
Name: transducer of ErbB-2.1
Synonyms: Trob, Tob
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22057
Homologene: 31334
Prl
Name: prolactin
Synonyms: Prl, Prl1a1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19109
HGNC: HGNC:9445
Homologene: 732
Arhgef28
Name: Rho guanine nucleotide exchange factor 28
Synonyms: D13Bwg1089e, Rho specific exchange factor, 9230110L08Rik, RIP2, Rgnef, p190RhoGEF, RhoGEF
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110596
VEGA: 13
Homologene: 8078
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 58178
Homologene: 10967
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: Nalp-theta, D7Ertd565e, Nalp9a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233001
Homologene: 116072
Mapk15
Name: mitogen-activated protein kinase 15
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 332110
Homologene: 16371
Fhad1
Name: forkhead-associated phosphopeptide binding domain 1
Synonyms: 2900090M10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329977
Homologene: 77947
Nlrp14
Name: NLR family, pyrin domain containing 14
Synonyms: GC-LRR, 4921520L01Rik, Nalp14, Nalp-iota
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76858
Homologene: 18531
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 0610038H21Rik, 2900056O04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68379
Homologene: 8112
Vmn2r110
Name: vomeronasal 2, receptor 110
Synonyms: EG224582
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224582
Homologene: 129678
Pla2g2c
Name: phospholipase A2, group IIC
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18781
HGNC: HGNC:9032
Homologene: 7477
Or6z5
Name: olfactory receptor family 6 subfamily Z member 5
Synonyms: MOR103-6, Olfr1346, GA_x6K02T2QGBW-3203957-3204898
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258918
Homologene: 74134
Npsr1
Name: neuropeptide S receptor 1
Synonyms: VRR1, Gpr154, PGR14, 9330128H10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319239
Homologene: 45515
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230622
Homologene: 135888
Klhl5
Name: kelch-like 5
Synonyms: 1300013C10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71778
HGNC: HGNC:6356
Homologene: 56736
Myo1c
Name: myosin IC
Synonyms: mm1beta, C80397, myr2, myosin-Ibeta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Or2w4
Name: olfactory receptor family 2 subfamily W member 4
Synonyms: Olfr1363-ps1, GA_x6K02T2QHY8-11628399-11628868, GA_x6K02T2QHY8-11617756-11618682, Olfr1362, MOR256-8
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258739
Homologene: 105885
Klhl10
Name: kelch-like 10
Synonyms: 4921517C11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66720
Homologene: 12018
Tcf21
Name: transcription factor 21
Synonyms: Pod1, epc, podocyte-expressed 1, epicardin, capsulin, bHLHa23, Pod-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21412
VEGA: 10
Homologene: 2414
Cpeb2
Name: cytoplasmic polyadenylation element binding protein 2
Synonyms: A630055H10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231207
Homologene: 17995
Ankrd24
Name: ankyrin repeat domain 24
Synonyms: 4631433D01Rik, 5730519E19Rik, D10Bur2e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70615
Homologene: 49885
Atxn1
Name: ataxin 1
Synonyms: 2900016G23Rik, Sca1, Atx1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20238
VEGA: 13
Homologene: 281
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Or4k48
Name: olfactory receptor family 4 subfamily K member 48
Synonyms: MOR248-6, GA_x6K02T2Q125-72697413-72696475, Olfr1298
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258888
Homologene: 121521
Gys2
Name: glycogen synthase 2
Synonyms: LGS, glycogen synthase, liver
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232493
HGNC: HGNC:4707
Homologene: 56580
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Op1, Mater, Nalp5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23968
Homologene: 65105
Cerk
Name: ceramide kinase
Synonyms: D330016D08Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223753
Homologene: 11247
Bcl2a1c
Name: B cell leukemia/lymphoma 2 related protein A1c
Synonyms: A1-c
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12046
HGNC: HGNC:991
Kcna7
Name: potassium voltage-gated channel, shaker-related subfamily, member 7
Synonyms: Kv1.7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16495
HGNC: HGNC:6226
Homologene: 7791
Tmem132a
Name: transmembrane protein 132A
Synonyms: 6720481D13Rik, Hspa5bp1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 98170
Homologene: 75076
Nectin1
Name: nectin cell adhesion molecule 1
Synonyms: HveC, PRR1, nectin-1, PRR, Cd111, Pvrl1, HIgR
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 58235
VEGA: 9
HGNC: HGNC:9706
Homologene: 2138
Vmn2r30
Name: vomeronasal 2, receptor 30
Synonyms: V2r15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22306
Homologene: 113703
Psg29
Name: pregnancy-specific beta-1-glycoprotein 29
Synonyms: cea17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 114872
Homologene: 83380
Ramp2
Name: receptor (calcitonin) activity modifying protein 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54409
HGNC: HGNC:9844
Homologene: 4274
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 150,748,190 bp (GRCm38)
  • A to G, chromosome 1 at 162,678,164 bp (GRCm38)
  • T to C, chromosome 2 at 10,251,410 bp (GRCm38)
  • A to T, chromosome 2 at 32,363,847 bp (GRCm38)
  • C to A, chromosome 2 at 111,645,319 bp (GRCm38)
  • G to T, chromosome 3 at 90,411,298 bp (GRCm38)
  • A to T, chromosome 3 at 129,215,818 bp (GRCm38)
  • T to C, chromosome 4 at 32,715,711 bp (GRCm38)
  • C to T, chromosome 4 at 112,809,163 bp (GRCm38)
  • T to A, chromosome 4 at 115,920,065 bp (GRCm38)
  • G to T, chromosome 4 at 136,938,586 bp (GRCm38)
  • T to C, chromosome 4 at 138,743,661 bp (GRCm38)
  • T to C, chromosome 4 at 141,909,813 bp (GRCm38)
  • T to C, chromosome 5 at 43,233,925 bp (GRCm38)
  • T to C, chromosome 5 at 65,162,912 bp (GRCm38)
  • A to G, chromosome 6 at 30,656,604 bp (GRCm38)
  • T to C, chromosome 6 at 35,232,575 bp (GRCm38)
  • A to G, chromosome 6 at 71,929,388 bp (GRCm38)
  • T to C, chromosome 6 at 119,743,399 bp (GRCm38)
  • A to C, chromosome 6 at 142,448,461 bp (GRCm38)
  • A to T, chromosome 7 at 6,474,211 bp (GRCm38)
  • A to G, chromosome 7 at 7,312,285 bp (GRCm38)
  • A to T, chromosome 7 at 17,210,570 bp (GRCm38)
  • T to G, chromosome 7 at 23,421,477 bp (GRCm38)
  • A to G, chromosome 7 at 26,567,841 bp (GRCm38)
  • A to G, chromosome 7 at 45,406,978 bp (GRCm38)
  • A to T, chromosome 7 at 107,197,780 bp (GRCm38)
  • A to G, chromosome 9 at 24,289,886 bp (GRCm38)
  • A to G, chromosome 9 at 43,803,943 bp (GRCm38)
  • G to A, chromosome 9 at 114,330,273 bp (GRCm38)
  • A to G, chromosome 10 at 5,324,184 bp (GRCm38)
  • T to C, chromosome 10 at 22,819,827 bp (GRCm38)
  • T to G, chromosome 10 at 81,647,117 bp (GRCm38)
  • G to A, chromosome 10 at 120,038,664 bp (GRCm38)
  • T to C, chromosome 11 at 30,815,294 bp (GRCm38)
  • T to C, chromosome 11 at 75,671,971 bp (GRCm38)
  • C to T, chromosome 11 at 94,214,228 bp (GRCm38)
  • T to A, chromosome 11 at 100,445,570 bp (GRCm38)
  • T to A, chromosome 11 at 101,247,087 bp (GRCm38)
  • A to G, chromosome 13 at 21,611,657 bp (GRCm38)
  • A to T, chromosome 13 at 27,064,355 bp (GRCm38)
  • G to A, chromosome 13 at 45,567,823 bp (GRCm38)
  • A to G, chromosome 13 at 97,957,753 bp (GRCm38)
  • T to A, chromosome 14 at 68,505,134 bp (GRCm38)
  • C to A, chromosome 14 at 72,540,253 bp (GRCm38)
  • T to A, chromosome 15 at 75,998,063 bp (GRCm38)
  • A to G, chromosome 15 at 86,149,290 bp (GRCm38)
  • A to G, chromosome 17 at 20,574,586 bp (GRCm38)
  • G to A, chromosome 19 at 10,863,314 bp (GRCm38)
  • G to A, chromosome 19 at 50,226,837 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9744 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069990-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.