Strain Name:
C57BL/6J-MtgxR9755Btlr/Mmmh
Stock Number:
070000-MU
Citation ID:
RRID:MMRRC_070000-MU
Other Names:
R9755 (G1)
Major Collection:

Strain Information

Sema3b
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Synonyms: Semaa, SemA, semaV, LUCA-1, SemA, sema5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20347
Homologene: 20972
Ndnf
Name: neuron-derived neurotrophic factor
Synonyms: epidermacan, A930038C07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68169
Homologene: 11593
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Skil
Name: SKI-like
Synonyms: SnoN2, Skir, 9130011J04Rik, SnoN, sno-dE3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20482
Homologene: 3948
Etl4
Name: enhancer trap locus 4
Synonyms: Skt, Sickle tail, 6620402G01Rik, E330027G05Rik, 9430077C05Rik, Etl-4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 208618
Homologene: 10477
Plcg1
Name: phospholipase C, gamma 1
Synonyms: Plc-gamma1, Plc-1, Plcg-1, Cded
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18803
HGNC: HGNC:9065
Homologene: 1997
Cacul1
Name: CDK2 associated, cullin domain 1
Synonyms: 9830127L17Rik, 2700078E11Rik, D130033C15Rik, 2810417M16Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78832
VEGA: 19
Homologene: 17821
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: Acinus, 2610036I19Rik, 2610510L13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56215
Homologene: 22853
Zfp318
Name: zinc finger protein 318
Synonyms: TZF, D530032D06Rik, 2610034E08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57908
Homologene: 22808
Golga3
Name: golgin A3
Synonyms: Mea2, 5430416E01Rik, repro27, Mea-2, G1-499-14
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269682
HGNC: HGNC:4426
Homologene: 4308
Arhgap33
Name: Rho GTPase activating protein 33
Synonyms: Tcgap, NOMA-GAP, Snx26
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233071
Homologene: 76448
Adgrl4
Name: adhesion G protein-coupled receptor L4
Synonyms: Eltd1, EGF-TM7 receptor, Etl, 1110033N21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170757
Homologene: 11170
Gramd1c
Name: GRAM domain containing 1C
Synonyms: 4921521N14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207798
Homologene: 129735
Amph
Name: amphiphysin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218038
HGNC: HGNC:471
Homologene: 121585
Mfsd14b
Name: major facilitator superfamily domain containing 14B
Synonyms: Hiatl1, 5730414C17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66631
Homologene: 64464
Slc44a4
Name: solute carrier family 44, member 4
Synonyms: 2210409B01Rik, NG22
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70129
Homologene: 11359
Zfp830
Name: zinc finger protein 830
Synonyms: Omcg1, 2410003C20Rik, Ccdc16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66983
Homologene: 41655
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: L-type Cav1.2, Cav1.2, D930026N18Rik, (alpha)1 subunit, Cchl1a1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Kcp
Name: kielin/chordin-like protein
Synonyms: KCP, LOC333088, Crim2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 333088
Homologene: 87817
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619697
Homologene: 86604
Scart2
Name: scavenger receptor family member expressed on T cells 2
Synonyms: 5830411N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244234
Homologene: 133218
Prmt6
Name: protein arginine N-methyltransferase 6
Synonyms: Hrmt1l6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99890
Homologene: 10024
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Adamts9
Name: ADAM metallopeptidase with thrombospondin type 1 motif 9
Synonyms: 8430403M15Rik, 1810011L16Rik, UND4, E030027K14Rik, Gsfund3, UND3, Mhdaund3, Mhdaund4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101401
Homologene: 18821
C1galt1
Name: core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
Synonyms: core 1 beta3-Gal-T, 2210410E06Rik, T-synthase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 94192
Homologene: 10599
Dhh
Name: desert hedgehog
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13363
VEGA: 15
HGNC: HGNC:2865
Homologene: 22431
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Prickle2
Name: prickle planar cell polarity protein 2
Synonyms: mpk2, 6720451F06Rik, 6230400G14Rik, Pk2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243548
Homologene: 17889
Mak
Name: male germ cell-associated kinase
Synonyms: A930010O05Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17152
VEGA: 13
HGNC: HGNC:6816
Homologene: 31344
Ppm1h
Name: protein phosphatase 1H (PP2C domain containing)
Synonyms: ARHCL1, A430075L18Rik, C030002B11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319468
Homologene: 18537
Csf2rb
Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Synonyms: Csf2rb1, Il3rb1, CDw131, Il3r, AIC2B, Il5rb, common beta chain, beta c, Bc
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12983
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Lrrc15
Name: leucine rich repeat containing 15
Synonyms: 5430427N11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74488
Homologene: 26080
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 28010
Homologene: 15879
Or12e7
Name: olfactory receptor family 12 subfamily E member 7
Synonyms: MOR264-5, GA_x6K02T2Q125-48959068-48960012, Olfr1126
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258834
Homologene: 133659
Cenpq
Name: centromere protein Q
Synonyms: 2610528M18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 83815
Homologene: 49525
Slc13a1
Name: solute carrier family 13 (sodium/sulfate symporters), member 1
Synonyms: NaSi-1, Nas1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 55961
Homologene: 31893
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192950
Homologene: 135717
Trpc4
Name: transient receptor potential cation channel, subfamily C, member 4
Synonyms: Trrp4, CCE1, Trp4, STRPC4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22066
Homologene: 22955
Mdfic2
Name: MyoD family inhibitor domain containing 2
Synonyms: LOC330390, Gm765
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330390
Homologene: 66631
Mdfic
Name: MyoD family inhibitor domain containing
Synonyms: Kdt1, clone 1.5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16543
Homologene: 18404
B4galnt2
Name: beta-1,4-N-acetyl-galactosaminyl transferase 2
Synonyms: Dlb1, Galgt2, Dlb-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14422
Homologene: 7329
Cfhr1
Name: complement factor H-related 1
Synonyms: Cfhl1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 50702
Homologene: 55632
Psg25
Name: pregnancy-specific beta-1-glycoprotein 25
Synonyms: cea13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 114868
HGNC: HGNC:1819
Homologene: 110989
Taar8a
Name: trace amine-associated receptor 8A
Synonyms: LOC215859
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215859
Homologene: 77586
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246228
Homologene: 11270
Nphp1
Name: nephronophthisis 1 (juvenile) homolog (human)
Synonyms: nephrocystin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 53885
HGNC: HGNC:7905
Homologene: 229
Cfap54
Name: cilia and flagella associated protein 54
Synonyms: LOC380653, Gm872, 4930485B16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380654
Homologene: 133438
Sapcd1
Name: suppressor APC domain containing 1
Synonyms: G7d, Ng23
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78376
Homologene: 86703
Or8g29-ps1
Name: olfactory receptor family 8 subfamily G member 29, pseudogene 1
Synonyms: GA_x6K02T2PVTD-32987171-32986232, MOR171-43, Olfr947-ps1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257924
VEGA: 9
Gnrh1
Name: gonadotropin releasing hormone 1
Synonyms: LNRH, LHRH
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14714
VEGA: 14
HGNC: HGNC:4419
Homologene: 641
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 139,560,151 bp (GRCm38)
  • A to T, chromosome 2 at 20,785,237 bp (GRCm38)
  • C to A, chromosome 2 at 87,457,375 bp (GRCm38)
  • G to A, chromosome 2 at 127,754,031 bp (GRCm38)
  • G to A, chromosome 2 at 160,731,860 bp (GRCm38)
  • A to G, chromosome 3 at 31,097,395 bp (GRCm38)
  • A to G, chromosome 3 at 54,315,794 bp (GRCm38)
  • A to C, chromosome 3 at 110,250,043 bp (GRCm38)
  • A to T, chromosome 3 at 151,510,781 bp (GRCm38)
  • A to T, chromosome 4 at 147,865,862 bp (GRCm38)
  • G to A, chromosome 4 at 155,772,879 bp (GRCm38)
  • A to G, chromosome 5 at 110,192,981 bp (GRCm38)
  • T to G, chromosome 6 at 7,867,019 bp (GRCm38)
  • G to T, chromosome 6 at 15,799,759 bp (GRCm38)
  • T to C, chromosome 6 at 24,134,408 bp (GRCm38)
  • T to C, chromosome 6 at 29,492,461 bp (GRCm38)
  • T to G, chromosome 6 at 65,703,518 bp (GRCm38)
  • C to T, chromosome 6 at 92,422,338 bp (GRCm38)
  • T to C, chromosome 6 at 92,879,941 bp (GRCm38)
  • A to T, chromosome 6 at 98,248,186 bp (GRCm38)
  • T to C, chromosome 6 at 118,674,598 bp (GRCm38)
  • A to T, chromosome 7 at 18,526,535 bp (GRCm38)
  • C to T, chromosome 7 at 30,528,501 bp (GRCm38)
  • G to A, chromosome 7 at 44,312,918 bp (GRCm38)
  • T to A, chromosome 7 at 140,261,631 bp (GRCm38)
  • A to G, chromosome 9 at 39,289,674 bp (GRCm38)
  • T to C, chromosome 9 at 107,601,585 bp (GRCm38)
  • T to C, chromosome 10 at 23,941,140 bp (GRCm38)
  • A to G, chromosome 10 at 24,077,097 bp (GRCm38)
  • T to A, chromosome 10 at 92,921,368 bp (GRCm38)
  • A to G, chromosome 10 at 122,802,260 bp (GRCm38)
  • A to G, chromosome 11 at 6,599,374 bp (GRCm38)
  • C to T, chromosome 11 at 82,764,979 bp (GRCm38)
  • G to A, chromosome 11 at 95,883,975 bp (GRCm38)
  • A to T, chromosome 13 at 19,113,155 bp (GRCm38)
  • G to T, chromosome 13 at 41,046,147 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • A to T, chromosome 14 at 54,651,835 bp (GRCm38)
  • G to A, chromosome 14 at 67,749,250 bp (GRCm38)
  • A to T, chromosome 14 at 103,314,370 bp (GRCm38)
  • T to G, chromosome 15 at 78,348,624 bp (GRCm38)
  • A to G, chromosome 15 at 98,895,058 bp (GRCm38)
  • T to A, chromosome 16 at 30,274,329 bp (GRCm38)
  • T to A, chromosome 16 at 43,983,516 bp (GRCm38)
  • A to T, chromosome 17 at 23,401,091 bp (GRCm38)
  • A to G, chromosome 17 at 34,917,355 bp (GRCm38)
  • A to G, chromosome 17 at 35,026,424 bp (GRCm38)
  • A to T, chromosome 17 at 40,932,821 bp (GRCm38)
  • A to G, chromosome 17 at 46,411,129 bp (GRCm38)
  • C to T, chromosome 19 at 60,545,517 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9755 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070000-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.