Strain Name:
C57BL/6J-MtgxR9785Btlr/Mmmh
Stock Number:
070030-MU
Citation ID:
RRID:MMRRC_070030-MU
Other Names:
R9785 (G1)
Major Collection:

Strain Information

Sh3gl2
Name: SH3-domain GRB2-like 2
Synonyms: EEN-B1, endophilin I, Sh3d2a, 9530001L19Rik, B930049H17Rik, endophilin A1, EEN1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20404
Homologene: 20652
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Gjd2
Name: gap junction protein, delta 2
Synonyms: connexin36, Cx36, Gja9
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14617
Homologene: 7734
Lgals8
Name: lectin, galactose binding, soluble 8
Synonyms: Lgals-8, 1200015E08Rik, D13Ertd524e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56048
HGNC: HGNC:6569
Homologene: 31386
Jam2
Name: junction adhesion molecule 2
Synonyms: 2410030G21Rik, JAM-2, VE-JAM, 2410167M24Rik, Jcam2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67374
Homologene: 10929
Scg3
Name: secretogranin III
Synonyms: SgIII, Chgd, 1B1075
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20255
VEGA: 9
Homologene: 7526
Mcm5
Name: minichromosome maintenance complex component 5
Synonyms: mCD46, Cdc46, Mcmd5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17218
HGNC: HGNC:6948
Homologene: 4904
Zbtb17
Name: zinc finger and BTB domain containing 17
Synonyms: mZ13, Miz1, Zfp100
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22642
Homologene: 2575
Gtf2b
Name: general transcription factor IIB
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229906
HGNC: HGNC:4648
Homologene: 1158
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: Lec2, lectomedin-2, 2900070I05Rik, Lphn1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330814
Homologene: 8951
Zdhhc6
Name: zinc finger, DHHC domain containing 6
Synonyms: 5930409M18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66980
VEGA: 19
Homologene: 41487
Armt1
Name: acidic residue methyltransferase 1
Synonyms: 1700052N19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 73419
Homologene: 41557
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233410
Homologene: 8759
Csn2
Name: casein beta
Synonyms: CSN2, Csnb
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12991
HGNC: HGNC:2447
Homologene: 1426
Rprm
Name: reprimo, TP53 dependent G2 arrest mediator candidate
Synonyms: Reprimo, 2410012A13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67874
Homologene: 10524
Tcf7
Name: transcription factor 7, T cell specific
Synonyms: TCF-1, T-cell factor 1, Tcf1, T cell factor-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21414
Homologene: 137220
Cebpb
Name: CCAAT/enhancer binding protein beta
Synonyms: NF-IL6, C/EBP BETA, Nfil6, NF-M, CRP2, LAP, IL-6DBP, C/EBPbeta, LIP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12608
HGNC: HGNC:1834
Homologene: 3807
Usf3
Name: upstream transcription factor family member 3
Synonyms: LOC207806, LOC385650, 5530400K22Rik, Gm608
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207806
Homologene: 19504
Gabra5
Name: gamma-aminobutyric acid type A receptor subunit alpha 5
Synonyms: A230018I05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110886
HGNC: HGNC:4079
Homologene: 20219
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: D-LTCC, Cchl1a, Cchl1a2, Cacnl1a2, 8430418G19Rik, Cav1.3alpha1, C79217
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Clec3b
Name: C-type lectin domain family 3, member b
Synonyms: Tna
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21922
VEGA: 9
Homologene: 31145
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242838
Homologene: 18247
Or10j7
Name: olfactory receptor family 10 subfamily J member 7
Synonyms: GA_x6K02T2R7CC-664297-665229, MOR267-5, Olfr1406
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258758
Homologene: 133644
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230622
Homologene: 135888
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22313
Homologene: 129751
Klhdc7b
Name: kelch domain containing 7B
Synonyms: EG546648
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 546648
Homologene: 34707
Dstyk
Name: dual serine/threonine and tyrosine protein kinase
Synonyms: A930019K20Rik, C430014H23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213452
Homologene: 19711
Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Synonyms: Niemann-Pick disease, type C1, 9130221N23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237636
HGNC: HGNC:7898
Homologene: 56585
Hrnr
Name: hornerin
Synonyms: 1110033K19Rik, A530063N20Rik, S100a18
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68723
Homologene: 138092
Zfp202
Name: zinc finger protein 202
Synonyms: C130037E22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 80902
Homologene: 68317
Dnm1
Name: dynamin 1
Synonyms: dynamin 1, Ftfl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13429
HGNC: HGNC:2972
Homologene: 123905
Alpk1
Name: alpha-kinase 1
Synonyms: 8430410J10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71481
Homologene: 11849
Srl
Name: sarcalumenin
Synonyms: sarcalumenin, sar, 9830004M20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106393
Homologene: 45500
Adamts14
Name: ADAM metallopeptidase with thrombospondin type 1 motif 14
Synonyms: TS14, Adamts-14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237360
Homologene: 16383
Cracd
Name: capping protein inhibiting regulator of actin
Synonyms: C530008M17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320827
Homologene: 136278
Or5d47
Name: olfactory receptor family 5 subfamily D member 47
Synonyms: mOR-EV, MOR174-4, GA_x6K02T2Q125-49458388-49457432, Olfr74
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 117005
Homologene: 74078
Ivd
Name: isovaleryl coenzyme A dehydrogenase
Synonyms: 6720455E18Rik, 1300016K07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56357
HGNC: HGNC:6186
Homologene: 1676
Wnt1
Name: wingless-type MMTV integration site family, member 1
Synonyms: Int-1, Wnt-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22408
Homologene: 3963
Selenon
Name: selenoprotein N
Synonyms: 1110019I12Rik, Sepn1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74777
Homologene: 10723
Cd27
Name: CD27 antigen
Synonyms: Cd27, S152, Tp55, Tnfrsf7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21940
Homologene: 74386
Trdv2-2
Name: T cell receptor delta variable 2-2
Synonyms: Gm17015
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 320913
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 132,453,300 bp (GRCm38)
  • C to T, chromosome 1 at 173,183,891 bp (GRCm38)
  • A to T, chromosome 2 at 32,333,077 bp (GRCm38)
  • C to T, chromosome 2 at 54,085,226 bp (GRCm38)
  • T to C, chromosome 2 at 87,973,901 bp (GRCm38)
  • A to T, chromosome 2 at 114,011,266 bp (GRCm38)
  • G to T, chromosome 2 at 118,880,489 bp (GRCm38)
  • A to G, chromosome 2 at 167,689,743 bp (GRCm38)
  • G to A, chromosome 3 at 93,331,554 bp (GRCm38)
  • A to T, chromosome 3 at 127,679,945 bp (GRCm38)
  • AATCATC to AATC, chromosome 3 at 142,771,417 bp (GRCm38)
  • T to A, chromosome 4 at 85,355,381 bp (GRCm38)
  • A to T, chromosome 4 at 112,883,687 bp (GRCm38)
  • C to T, chromosome 4 at 134,543,063 bp (GRCm38)
  • C to T, chromosome 4 at 141,466,960 bp (GRCm38)
  • T to C, chromosome 5 at 3,858,708 bp (GRCm38)
  • A to T, chromosome 5 at 76,867,181 bp (GRCm38)
  • A to T, chromosome 5 at 87,694,643 bp (GRCm38)
  • G to A, chromosome 6 at 125,236,982 bp (GRCm38)
  • C to T, chromosome 7 at 57,490,836 bp (GRCm38)
  • G to T, chromosome 7 at 81,023,497 bp (GRCm38)
  • C to T, chromosome 8 at 75,117,540 bp (GRCm38)
  • A to T, chromosome 8 at 83,938,539 bp (GRCm38)
  • A to G, chromosome 9 at 40,208,937 bp (GRCm38)
  • G to T, chromosome 9 at 75,682,040 bp (GRCm38)
  • T to A, chromosome 9 at 123,156,932 bp (GRCm38)
  • T to A, chromosome 10 at 4,439,606 bp (GRCm38)
  • T to C, chromosome 10 at 61,213,648 bp (GRCm38)
  • C to T, chromosome 11 at 6,230,090 bp (GRCm38)
  • T to A, chromosome 11 at 52,282,946 bp (GRCm38)
  • A to T, chromosome 13 at 12,447,170 bp (GRCm38)
  • A to T, chromosome 14 at 30,102,343 bp (GRCm38)
  • A to T, chromosome 14 at 53,961,032 bp (GRCm38)
  • G to T, chromosome 15 at 89,388,418 bp (GRCm38)
  • G to T, chromosome 15 at 98,790,871 bp (GRCm38)
  • A to G, chromosome 16 at 4,496,854 bp (GRCm38)
  • A to G, chromosome 16 at 44,221,607 bp (GRCm38)
  • T to C, chromosome 16 at 84,774,509 bp (GRCm38)
  • G to A, chromosome 17 at 20,048,147 bp (GRCm38)
  • T to C, chromosome 17 at 57,478,930 bp (GRCm38)
  • T to C, chromosome 19 at 55,311,771 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9785 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070030-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.