Strain Name:
C57BL/6J-MtgxR9795Btlr/Mmmh
Stock Number:
070040-MU
Citation ID:
RRID:MMRRC_070040-MU
Other Names:
R9795 (G1)
Major Collection:

Strain Information

Mitf
Name: melanogenesis associated transcription factor
Synonyms: mi, wh, bHLHe32, BCC2, Gsfbcc2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17342
HGNC: HGNC:7105
Homologene: 4892
Adamts20
Name: ADAM metallopeptidase with thrombospondin type 1 motif 20
Synonyms: ADAMTS-20, bt
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223838
Homologene: 11808
Ano1
Name: anoctamin 1, calcium activated chloride channel
Synonyms: Tmem16a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101772
Homologene: 75079
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: 5430402I23Rik, LEC3, Lphn3, D130075K09Rik, lectomedin 3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319387
Homologene: 22878
Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330953
VEGA: 9
Homologene: 3997
Rsf1
Name: remodeling and spacing factor 1
Synonyms: 4832420A03Rik, p325, C030033M12Rik, Hbxap, XAP8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Qrich1
Name: glutamine-rich 1
Synonyms: 2610028H07Rik, b2b2404Clo
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69232
Homologene: 9803
Rasgrp1
Name: RAS guanyl releasing protein 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19419
HGNC: HGNC:9878
Homologene: 4195
Stx7
Name: syntaxin 7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 53331
VEGA: 10
Homologene: 37823
Wdr26
Name: WD repeat domain 26
Synonyms: 1600024A01Rik, Gid7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226757
Homologene: 11857
Cald1
Name: caldesmon 1
Synonyms: 4833423D12Rik, C920027I18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109624
HGNC: HGNC:1441
Homologene: 137254
Nsd2
Name: nuclear receptor binding SET domain protein 2
Synonyms: 9430010A17Rik, 5830445G22Rik, D930023B08Rik, Whsc1l, C130020C13Rik, D030027O06Rik, Whsc1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 107823
Homologene: 26175
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: adenomatosis polyposis coli, CC1, Min
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Cdk12
Name: cyclin dependent kinase 12
Synonyms: Crkrs, D11Ertd752e, 1810022J16Rik, Crk7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69131
Homologene: 128632
Ppip5k2
Name: diphosphoinositol pentakisphosphate kinase 2
Synonyms: Cfap160, Hisppd1, Vip2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227399
Homologene: 49409
Pcdh17
Name: protocadherin 17
Synonyms: C030033F14Rik, LOC219228
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Calhm6
Name: calcium homeostasis modulator family member 6
Synonyms: A630077B13Rik, Fam26f
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215900
VEGA: 10
Homologene: 25235
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Epha3
Name: Eph receptor A3
Synonyms: Tyro4, Hek, Hek4, Mek4, End3, Cek4
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13837
VEGA: 16
HGNC: HGNC:3387
Homologene: 21083
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: fibrocystin L, PKHDL1, D86 mRNA
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Or4a78
Name: olfactory receptor family 4 subfamily A member 78
Synonyms: MOR231-24_p, Olfr1251, MOR231-15P, GA_x6K02T2Q125-51109312-51108356
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259145
Homologene: 74065
Afap1l1
Name: actin filament associated protein 1-like 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 106877
Homologene: 18728
Cfap53
Name: cilia and flagella associated protein 53
Synonyms: 4933415I03Rik, Ccdc11
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 74453
Homologene: 27056
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216225
VEGA: 10
Homologene: 64832
Cntnap4
Name: contactin associated protein-like 4
Synonyms: Caspr4, E130114F09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170571
Homologene: 24912
Krt73
Name: keratin 73
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223915
Homologene: 27875
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75777
Homologene: 44907
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Sel1l3
Name: sel-1 suppressor of lin-12-like 3 (C. elegans)
Synonyms: 2310045A20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231238
Homologene: 9054
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1, Mtap1a, Mtap-1, 6330416M19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Nuggc
Name: nuclear GTPase, germinal center associated
Synonyms: SLIP-GC, LOC239151, Gm600
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100503545
Homologene: 72641
Slc6a7
Name: solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms: Prot
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240332
VEGA: 18
Homologene: 8592
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319807
Homologene: 14974
Or7e170
Name: olfactory receptor family 7 subfamily E member 170
Synonyms: GA_x6K02T2PVTD-13624132-13623212, MOR146-1, Olfr862
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258555
Homologene: 115540
Or7g32
Name: olfactory receptor family 7 subfamily G member 32
Synonyms: Olfr851, MOR155-1, GA_x6K02T2PVTD-13234278-13235216
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258907
HGNC: HGNC:8466
Homologene: 74178
Or8h9
Name: olfactory receptor family 8 subfamily H member 9
Synonyms: GA_x6K02T2Q125-48446067-48445129, MOR206-3, Olfr1099
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258764
Homologene: 107003
Foxred1
Name: FAD-dependent oxidoreductase domain containing 1
Synonyms: Tex23, TEG-23
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235169
Homologene: 9712
Sult1d1
Name: sulfotransferase family 1D, member 1
Synonyms: tyrosine-ester sulfotransferase, Sultn, 5033411P13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53315
Homologene: 124464
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Dffry, Fafl2
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 107868
Homologene: 68408
Or5p79
Name: olfactory receptor family 5 subfamily P member 79
Synonyms: MOR204-7, GA_x6K02T2PBJ9-10951546-10952496, Olfr507
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258738
Homologene: 27249
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: EG668547, EG383258, Vmn2r119
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383258
Homologene: 129687
Bbs12
Name: Bardet-Biedl syndrome 12
Synonyms: LOC386537, LOC241950, LOC241950
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241950
Homologene: 17634
Rbm20
Name: RNA binding motif protein 20
Synonyms: 2010003H22Rik, 1110018J23Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73713
Homologene: 28386
Usp31
Name: ubiquitin specific peptidase 31
Synonyms: 6330567E21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76179
Homologene: 44504
Or2y1
Name: olfactory receptor family 2 subfamily Y member 1
Synonyms: GA_x6K02T2QP88-5941817-5940888, MOR256-42P, MOR256-42P, Olfr1385, MOR256-41P, Olfr1549-ps1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258027
Homologene: 86692
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627367
Homologene: 115024
Lrriq3
Name: leucine-rich repeats and IQ motif containing 3
Synonyms: 4930438B07Rik, 4930511J15Rik, 4933403H06Rik, Lrrc44
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74435
Homologene: 23668
Slc27a3
Name: solute carrier family 27 (fatty acid transporter), member 3
Synonyms: FATP3, Acsvl3, fatty acid transport protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26568
Homologene: 11529
Nr1h4
Name: nuclear receptor subfamily 1, group H, member 4
Synonyms: HRR1, Rxrip14, Fxr, FXR, RIP14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20186
HGNC: HGNC:7967
Homologene: 3760
Or5ac17
Name: olfactory receptor family 5 subfamily AC member 17
Synonyms: Olfr199, GA_x54KRFPKG5P-55430495-55429569, MOR182-14
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404310
Homologene: 37011
Ly6e
Name: lymphocyte antigen 6 family member E
Synonyms: Tsa1, 9804, Ly67, TSA-1, RIG-E, Sca-2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17069
HGNC: HGNC:6727
Homologene: 56411
Hao1
Name: hydroxyacid oxidase 1, liver
Synonyms: Hao-1, GOX, Gox1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15112
HGNC: HGNC:4809
Homologene: 6578
Pacsin3
Name: protein kinase C and casein kinase substrate in neurons 3
Synonyms: 4921507A02Rik, 6330413E15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80708
HGNC: HGNC:8572
Homologene: 41117
Ccdc9b
Name: coiled-coil domain containing 9B
Synonyms: A430105I19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214239
Homologene: 128188
Gstt1
Name: glutathione S-transferase, theta 1
Synonyms: Gstt1-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14871
HGNC: HGNC:4641
Homologene: 134739
Zfp51
Name: zinc finger protein 51
Synonyms: zfec12, Zfp-51
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22709
VEGA: 17
Homologene: 134003
Igkv4-79
Name: immunoglobulin kappa variable 4-79
Synonyms: LOC213684, IgVk ae4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213684
Or4f14c
Name: olfactory receptor family 4 subfamily F member 14C
Synonyms: MOR245-1, GA_x6K02T2Q125-73157028-73156524, Olfr1315
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404497
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 97,744,097 bp (GRCm38)
  • G to A, chromosome 1 at 150,732,938 bp (GRCm38)
  • A to G, chromosome 1 at 181,209,247 bp (GRCm38)
  • T to A, chromosome 2 at 86,958,775 bp (GRCm38)
  • T to C, chromosome 2 at 89,667,467 bp (GRCm38)
  • C to A, chromosome 2 at 91,263,815 bp (GRCm38)
  • T to C, chromosome 2 at 112,110,985 bp (GRCm38)
  • T to C, chromosome 2 at 117,287,948 bp (GRCm38)
  • T to C, chromosome 2 at 118,757,303 bp (GRCm38)
  • T to C, chromosome 2 at 121,290,823 bp (GRCm38)
  • T to A, chromosome 2 at 134,530,632 bp (GRCm38)
  • C to T, chromosome 3 at 37,320,075 bp (GRCm38)
  • C to T, chromosome 3 at 90,389,568 bp (GRCm38)
  • T to C, chromosome 3 at 155,187,676 bp (GRCm38)
  • A to G, chromosome 5 at 33,846,145 bp (GRCm38)
  • C to A, chromosome 5 at 53,172,582 bp (GRCm38)
  • A to G, chromosome 5 at 63,806,889 bp (GRCm38)
  • T to C, chromosome 5 at 81,689,574 bp (GRCm38)
  • T to A, chromosome 5 at 87,564,796 bp (GRCm38)
  • A to T, chromosome 6 at 34,746,136 bp (GRCm38)
  • A to G, chromosome 6 at 69,043,185 bp (GRCm38)
  • A to G, chromosome 6 at 97,993,182 bp (GRCm38)
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp (GRCm38)
  • A to G, chromosome 7 at 108,622,662 bp (GRCm38)
  • A to G, chromosome 7 at 121,648,276 bp (GRCm38)
  • A to T, chromosome 7 at 144,621,697 bp (GRCm38)
  • T to C, chromosome 8 at 112,881,725 bp (GRCm38)
  • T to C, chromosome 9 at 19,497,116 bp (GRCm38)
  • T to A, chromosome 9 at 19,884,051 bp (GRCm38)
  • CGGG to CGG, chromosome 9 at 35,210,856 bp (GRCm38)
  • C to T, chromosome 9 at 58,853,479 bp (GRCm38)
  • T to A, chromosome 9 at 108,533,890 bp (GRCm38)
  • T to C, chromosome 10 at 24,181,577 bp (GRCm38)
  • T to C, chromosome 10 at 34,126,548 bp (GRCm38)
  • T to C, chromosome 10 at 75,798,557 bp (GRCm38)
  • T to C, chromosome 10 at 88,921,729 bp (GRCm38)
  • T to G, chromosome 10 at 89,478,789 bp (GRCm38)
  • A to T, chromosome 11 at 49,495,055 bp (GRCm38)
  • T to A, chromosome 11 at 98,211,225 bp (GRCm38)
  • A to T, chromosome 12 at 84,829,354 bp (GRCm38)
  • T to C, chromosome 14 at 65,609,896 bp (GRCm38)
  • C to T, chromosome 14 at 84,532,910 bp (GRCm38)
  • T to A, chromosome 15 at 10,537,645 bp (GRCm38)
  • T to C, chromosome 15 at 44,543,587 bp (GRCm38)
  • G to T, chromosome 15 at 74,958,541 bp (GRCm38)
  • C to T, chromosome 15 at 94,403,299 bp (GRCm38)
  • C to A, chromosome 15 at 101,802,290 bp (GRCm38)
  • T to A, chromosome 16 at 59,216,575 bp (GRCm38)
  • T to C, chromosome 16 at 63,552,547 bp (GRCm38)
  • T to A, chromosome 17 at 18,947,299 bp (GRCm38)
  • T to G, chromosome 17 at 21,461,789 bp (GRCm38)
  • T to C, chromosome 17 at 55,592,496 bp (GRCm38)
  • A to T, chromosome 17 at 58,102,197 bp (GRCm38)
  • T to A, chromosome 18 at 34,314,575 bp (GRCm38)
  • C to A, chromosome 18 at 61,005,794 bp (GRCm38)
  • T to C, chromosome 18 at 61,741,751 bp (GRCm38)
  • A to G, chromosome 18 at 74,305,670 bp (GRCm38)
  • C to A, chromosome 19 at 53,864,120 bp (GRCm38)
  • T to C, chromosome Y at 1,364,679 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9795 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070040-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.