Strain Name:
C57BL/6J-MtgxR9802Btlr/Mmmh
Stock Number:
070047-MU
Citation ID:
RRID:MMRRC_070047-MU
Other Names:
R9802 (G1)
Major Collection:

Strain Information

Lhx5
Name: LIM homeobox protein 5
Synonyms: Lim2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16873
Homologene: 40621
Cdh11
Name: cadherin 11
Synonyms: OB-cadherin, osteoblast-cadherin, Cad11
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: D630035I23Rik, TRIP8, 5430433L24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Egr1
Name: early growth response 1
Synonyms: Krox-1, Krox-24, ETR103, NGF1-A, A530045N19Rik, Zfp-6, Krox24, Zenk, Zif268, Egr-1, NGFI-A, NGFIA, TIS8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13653
HGNC: HGNC:3238
Homologene: 56394
Abcc8
Name: ATP-binding cassette, sub-family C member 8
Synonyms: SUR1, D930031B21Rik, Sur
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Ybx3
Name: Y box protein 3
Synonyms: oxyR, dbpA, Dpba, MSY3, Csda, Yb2, MSY4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56449
HGNC: HGNC:2428
Homologene: 2708
Mib1
Name: MIB E3 ubiquitin protein ligase 1
Synonyms: E430019M12Rik, mindbomb, skeletrophin, Mib, mind bomb-1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225164
Homologene: 10810
Naa15
Name: N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Synonyms: ASTBDN, tubedown, Tbdn-1, mNAT1, 5730450D16Rik, Narg1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74838
Homologene: 14211
Prkab1
Name: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Synonyms: 1300015D22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19079
HGNC: HGNC:9378
Homologene: 38160
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20286
VEGA: 15
Homologene: 9735
Anln
Name: anillin, actin binding protein
Synonyms: Scraps, 2900037I21Rik, 1110037A17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68743
VEGA: 9
Homologene: 41281
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213895
Homologene: 7065
Bltp3b
Name: bridge-like lipid transfer protein family member 3B
Synonyms: 4930506D01Rik, E030041M21Rik, Uhrf1bp1l, 2010319N22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75089
VEGA: 10
Homologene: 12590
Rsf1
Name: remodeling and spacing factor 1
Synonyms: 4832420A03Rik, p325, C030033M12Rik, Hbxap, XAP8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Txnrd3
Name: thioredoxin reductase 3
Synonyms: TR2, Tgr
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232223
Homologene: 60033
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67534
Homologene: 8764
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Dock7
Name: dedicator of cytokinesis 7
Synonyms: LOC242555, 3110056M06Rik, m
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67299
Homologene: 23566
Tsr1
Name: TSR1 20S rRNA accumulation
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104662
Homologene: 5576
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Nxf1
Name: nuclear RNA export factor 1
Synonyms: Tip associated protein, Mvb1, Mex67, TAP
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 53319
HGNC: HGNC:8071
Homologene: 38176
Mfsd14b
Name: major facilitator superfamily domain containing 14B
Synonyms: Hiatl1, 5730414C17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66631
Homologene: 64464
Inpp5f
Name: inositol polyphosphate-5-phosphatase F
Synonyms: SAC2, 5830435P03Rik, cI-27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101490
Homologene: 8962
Alg8
Name: ALG8 alpha-1,3-glucosyltransferase
Synonyms: LOC381903
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381903
Homologene: 6931
Gipc3
Name: GIPC PDZ domain containing family, member 3
Synonyms: Rgs19ip3, Gipc3, Ahl5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209047
Homologene: 77068
Dclk3
Name: doublecortin-like kinase 3
Synonyms: Click-I, -II related, Dcamkl3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245038
Homologene: 70580
Ighd
Name: immunoglobulin heavy constant delta
Synonyms: IgD
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380797
HGNC: HGNC:5480
Med12l
Name: mediator complex subunit 12-like
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329650
Homologene: 43143
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Cpfl8, dice, 6820443O06Rik, nesprin-2, syne-2, Nesp2g, diminished cone electroretinogram
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Eln
Name: elastin
Synonyms: tropoelastin, E030024M20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13717
HGNC: HGNC:3327
Skint3
Name: selection and upkeep of intraepithelial T cells 3
Synonyms: A430090E18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 195564
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Opn5
Name: opsin 5
Synonyms: Gpr136, Neuropsin, TMEM13, PGR12
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 353344
VEGA: 17
Homologene: 72341
Plcl1
Name: phospholipase C-like 1
Synonyms: C230017K02Rik, PRIP-1, PLC-L
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227120
HGNC: HGNC:9063
Homologene: 38155
Vmn1r195
Name: vomeronasal 1 receptor 195
Synonyms: V1ri6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171257
Homologene: 110880
Zfp607a
Name: zinc finger protein 607A
Synonyms: 4732475C15Rik, Zfp607
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545938
Homologene: 134321
Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
Synonyms: C130026N12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71751
VEGA: 16
HGNC: HGNC:6852
Homologene: 37958
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
T
Name: brachyury, T-box transcription factor T
Synonyms: T1, Bra, Tbxt
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20997
Homologene: 2393
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243961
Homologene: 22949
Hnf4g
Name: hepatocyte nuclear factor 4, gamma
Synonyms: NR2A2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 30942
HGNC: HGNC:5026
Homologene: 37886
Serpinb9e
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9e
Synonyms: Spi14, ovalbumin, NK26
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20710
HGNC: HGNC:8955
Homologene: 69093
Hcfc2
Name: host cell factor C2
Synonyms: 1700129L13Rik, fkls
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67933
Homologene: 8337
Slc47a1
Name: solute carrier family 47, member 1
Synonyms: MATE1, 1300013J15Rik, mMATE1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67473
Homologene: 34364
Akr1b1
Name: aldo-keto reductase family 1 member B
Synonyms: Ahr-1, Akr1b3, Ahr1, Aldr1, ALR2, Aldor1, AR
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11677
HGNC: HGNC:381
Homologene: 133743
Igkv3-10
Name: immunoglobulin kappa variable 3-10
Synonyms: V-kappa-21B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667924
Mutyh
Name: mutY DNA glycosylase
Synonyms: Mutyhalpha, 5730495A01Rik, Mutyhbeta, Mutyhb, Mutyhc, Mutyha, Myh
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70603
HGNC: HGNC:7527
Homologene: 8156
Mrgpra6
Name: MAS-related GPR, member A6
Synonyms: MrgA6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381886
Or4c11b
Name: olfactory receptor family 4 subfamily C member 11B
Synonyms: Olfr1201, MOR230-2, GA_x6K02T2Q125-50268830-50269753
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258897
Homologene: 81567
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 53,522,229 bp (GRCm38)
  • T to C, chromosome 1 at 55,696,082 bp (GRCm38)
  • A to G, chromosome 1 at 74,681,323 bp (GRCm38)
  • T to C, chromosome 1 at 150,808,640 bp (GRCm38)
  • T to A, chromosome 2 at 88,795,147 bp (GRCm38)
  • A to T, chromosome 3 at 3,634,344 bp (GRCm38)
  • T to A, chromosome 3 at 51,441,949 bp (GRCm38)
  • T to C, chromosome 3 at 59,261,925 bp (GRCm38)
  • T to C, chromosome 4 at 98,958,147 bp (GRCm38)
  • T to A, chromosome 4 at 112,253,897 bp (GRCm38)
  • A to G, chromosome 4 at 116,819,288 bp (GRCm38)
  • T to C, chromosome 5 at 116,024,215 bp (GRCm38)
  • T to A, chromosome 5 at 120,434,598 bp (GRCm38)
  • C to A, chromosome 5 at 134,715,705 bp (GRCm38)
  • T to C, chromosome 6 at 34,306,573 bp (GRCm38)
  • T to C, chromosome 6 at 70,573,017 bp (GRCm38)
  • T to A, chromosome 6 at 85,629,238 bp (GRCm38)
  • T to A, chromosome 6 at 89,663,194 bp (GRCm38)
  • T to A, chromosome 6 at 118,391,186 bp (GRCm38)
  • G to A, chromosome 6 at 131,368,463 bp (GRCm38)
  • A to T, chromosome 7 at 27,879,279 bp (GRCm38)
  • G to A, chromosome 7 at 44,312,918 bp (GRCm38)
  • T to C, chromosome 7 at 46,136,630 bp (GRCm38)
  • C to T, chromosome 7 at 47,185,785 bp (GRCm38)
  • T to A, chromosome 7 at 97,378,279 bp (GRCm38)
  • GGCG to GGCGACGGCCGCG, chromosome 7 at 97,579,906 bp (GRCm38)
  • A to C, chromosome 7 at 128,676,791 bp (GRCm38)
  • A to G, chromosome 8 at 11,443,104 bp (GRCm38)
  • G to A, chromosome 8 at 102,664,644 bp (GRCm38)
  • T to C, chromosome 9 at 22,334,157 bp (GRCm38)
  • A to G, chromosome 9 at 111,469,176 bp (GRCm38)
  • A to T, chromosome 10 at 67,224,966 bp (GRCm38)
  • G to A, chromosome 10 at 81,343,263 bp (GRCm38)
  • G to T, chromosome 10 at 82,738,435 bp (GRCm38)
  • G to A, chromosome 10 at 89,779,893 bp (GRCm38)
  • T to C, chromosome 11 at 58,994,363 bp (GRCm38)
  • A to T, chromosome 11 at 61,349,516 bp (GRCm38)
  • T to C, chromosome 11 at 74,908,399 bp (GRCm38)
  • A to G, chromosome 12 at 75,990,423 bp (GRCm38)
  • G to A, chromosome 12 at 113,407,835 bp (GRCm38)
  • T to C, chromosome 13 at 22,279,103 bp (GRCm38)
  • T to C, chromosome 13 at 33,255,095 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • C to G, chromosome 13 at 100,426,205 bp (GRCm38)
  • C to T, chromosome 15 at 81,792,304 bp (GRCm38)
  • C to A, chromosome 16 at 21,921,768 bp (GRCm38)
  • G to A, chromosome 17 at 8,436,156 bp (GRCm38)
  • G to A, chromosome 17 at 42,592,691 bp (GRCm38)
  • T to A, chromosome 18 at 10,798,494 bp (GRCm38)
  • T to C, chromosome 18 at 34,862,621 bp (GRCm38)
  • G to A, chromosome 19 at 8,762,408 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9802 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070047-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.