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Strain Name:
C57BL/6J-MtgxR9802Btlr/Mmmh
Stock Number:
070047-MU
Citation ID:
RRID:MMRRC_070047-MU
Other Names:
R9802 (G1)
Major Collection:

Strain Information

Lhx5
Name: LIM homeobox protein 5
Synonyms: Lim2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16873
Homologene: 40621
Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, OB-cadherin, Cad11
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Egr1
Name: early growth response 1
Synonyms: TIS8, NGFIA, Krox24, Zenk, Zif268, ETR103, Krox-24, Krox-1, Egr-1, Zfp-6, NGF1-A, A530045N19Rik, NGFI-A
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13653
HGNC: HGNC:3238
Homologene: 56394
Abcc8
Name: ATP-binding cassette, sub-family C member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Ybx3
Name: Y box protein 3
Synonyms: MSY4, dbpA, oxyR, Dpba, Yb2, MSY3, Csda
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56449
HGNC: HGNC:2428
Homologene: 2708
Mib1
Name: MIB E3 ubiquitin protein ligase 1
Synonyms: E430019M12Rik, Mib, skeletrophin, mind bomb-1, mindbomb
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225164
Homologene: 10810
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 53,522,229 bp (GRCm38)
  • T to C, chromosome 1 at 55,696,082 bp (GRCm38)
  • A to G, chromosome 1 at 74,681,323 bp (GRCm38)
  • T to C, chromosome 1 at 150,808,640 bp (GRCm38)
  • T to A, chromosome 2 at 88,795,147 bp (GRCm38)
  • A to T, chromosome 3 at 3,634,344 bp (GRCm38)
  • T to A, chromosome 3 at 51,441,949 bp (GRCm38)
  • T to C, chromosome 3 at 59,261,925 bp (GRCm38)
  • T to C, chromosome 4 at 98,958,147 bp (GRCm38)
  • T to A, chromosome 4 at 112,253,897 bp (GRCm38)
  • A to G, chromosome 4 at 116,819,288 bp (GRCm38)
  • T to C, chromosome 5 at 116,024,215 bp (GRCm38)
  • T to A, chromosome 5 at 120,434,598 bp (GRCm38)
  • C to A, chromosome 5 at 134,715,705 bp (GRCm38)
  • T to C, chromosome 6 at 34,306,573 bp (GRCm38)
  • T to C, chromosome 6 at 70,573,017 bp (GRCm38)
  • T to A, chromosome 6 at 85,629,238 bp (GRCm38)
  • T to A, chromosome 6 at 89,663,194 bp (GRCm38)
  • T to A, chromosome 6 at 118,391,186 bp (GRCm38)
  • G to A, chromosome 6 at 131,368,463 bp (GRCm38)
  • A to T, chromosome 7 at 27,879,279 bp (GRCm38)
  • G to A, chromosome 7 at 44,312,918 bp (GRCm38)
  • T to C, chromosome 7 at 46,136,630 bp (GRCm38)
  • C to T, chromosome 7 at 47,185,785 bp (GRCm38)
  • T to A, chromosome 7 at 97,378,279 bp (GRCm38)
  • GGCG to GGCGACGGCCGCG, chromosome 7 at 97,579,906 bp (GRCm38)
  • A to C, chromosome 7 at 128,676,791 bp (GRCm38)
  • A to G, chromosome 8 at 11,443,104 bp (GRCm38)
  • G to A, chromosome 8 at 102,664,644 bp (GRCm38)
  • T to C, chromosome 9 at 22,334,157 bp (GRCm38)
  • A to G, chromosome 9 at 111,469,176 bp (GRCm38)
  • A to T, chromosome 10 at 67,224,966 bp (GRCm38)
  • G to A, chromosome 10 at 81,343,263 bp (GRCm38)
  • G to T, chromosome 10 at 82,738,435 bp (GRCm38)
  • G to A, chromosome 10 at 89,779,893 bp (GRCm38)
  • T to C, chromosome 11 at 58,994,363 bp (GRCm38)
  • A to T, chromosome 11 at 61,349,516 bp (GRCm38)
  • T to C, chromosome 11 at 74,908,399 bp (GRCm38)
  • A to G, chromosome 12 at 75,990,423 bp (GRCm38)
  • G to A, chromosome 12 at 113,407,835 bp (GRCm38)
  • T to C, chromosome 13 at 22,279,103 bp (GRCm38)
  • T to C, chromosome 13 at 33,255,095 bp (GRCm38)
  • C to A, chromosome 13 at 65,073,600 bp (GRCm38)
  • C to G, chromosome 13 at 100,426,205 bp (GRCm38)
  • C to T, chromosome 15 at 81,792,304 bp (GRCm38)
  • C to A, chromosome 16 at 21,921,768 bp (GRCm38)
  • G to A, chromosome 17 at 8,436,156 bp (GRCm38)
  • G to A, chromosome 17 at 42,592,691 bp (GRCm38)
  • T to A, chromosome 18 at 10,798,494 bp (GRCm38)
  • T to C, chromosome 18 at 34,862,621 bp (GRCm38)
  • G to A, chromosome 19 at 8,762,408 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9802 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070047-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.