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Strain Name:
C57BL/6J-MtgxR0077Btlr/Mmmh
Stock Number:
038364-MU
Citation ID:
RRID:MMRRC_038364-MU
Other Names:
R0077 (G1), C57BL/6J-MtgxR0077Btlr
Major Collection:

Strain Information

Septin4
Name: septin 4
Synonyms: cell division control-related protein 2b, Pnutl2, Bh5, septin H5, Gm11492, ARTS, Sept4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18952
HGNC: HGNC:9165
Homologene: 6107
Rbms1
Name: RNA binding motif, single stranded interacting protein 1
Synonyms: YC1, MSSP-3, MSSP-2, MSSP-1, 2600014B10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56878
HGNC: HGNC:9907
Homologene: 9640
Ddx23
Name: DEAD box helicase 23
Synonyms: 4921506D17Rik, 3110082M05Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74351
Homologene: 3542
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: D130075K09Rik, lectomedin 3, LEC3, 5430402I23Rik, Lphn3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319387
Homologene: 22878
Wfs1
Name: wolframin ER transmembrane glycoprotein
Synonyms: wolframin, Wolfram syndrome 1 homolog (human)
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22393
Homologene: 4380
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Tbcd
Name: tubulin-specific chaperone d
Synonyms: A030005L14Rik, 2310057L06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108903
Homologene: 4368
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228850
Homologene: 10666
Setdb1
Name: SET domain, bifurcated 1
Synonyms: ESET, KMT1E
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 84505
Homologene: 32157
Chaf1a
Name: chromatin assembly factor 1, subunit A
Synonyms: CAF-1, p150
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27221
VEGA: 17
HGNC: HGNC:1910
Homologene: 4003
Nr2c1
Name: nuclear receptor subfamily 2, group C, member 1
Synonyms: TR2, Tr2-11, 4831444H07Rik, Eenr
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22025
HGNC: HGNC:7971
Homologene: 55731
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Angel2
Name: angel homolog 2
Synonyms: 5730410O10Rik, 2610307I21Rik, D1Ertd654e, D1Ertd396e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52477
Homologene: 16932
Osr1
Name: odd-skipped related transcription factor 1
Synonyms: Odd1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23967
VEGA: 12
HGNC: HGNC:8111
Homologene: 8035
Xpot
Name: exportin, tRNA (nuclear export receptor for tRNAs)
Synonyms: EXPORTIN-T, C79645, 1110004L07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 73192
VEGA: 10
Homologene: 38291
Snrnp40
Name: small nuclear ribonucleoprotein 40 (U5)
Synonyms: 0610009C03Rik, Wdr57
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66585
Homologene: 3538
Zfp846
Name: zinc finger protein 846
Synonyms: 2210010B09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244721
Homologene: 87243
Adgrl4
Name: adhesion G protein-coupled receptor L4
Synonyms: EGF-TM7 receptor, Etl, 1110033N21Rik, Eltd1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170757
Homologene: 11170
Lrrtm1
Name: leucine rich repeat transmembrane neuronal 1
Synonyms: 4632401D06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74342
Homologene: 41763
Dmkn
Name: dermokine
Synonyms: cI-36, sk30, sk89, Dmkn, dermokine, 1110014F24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73712
Homologene: 136295
Lctl
Name: lactase-like
Synonyms: KLPH, E130104I05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235435
Homologene: 70710
Tsc1
Name: TSC complex subunit 1
Synonyms: hamartin, tuberous sclerosis 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 64930
Homologene: 314
Alg12
Name: ALG12 alpha-1,6-mannosyltransferase
Synonyms: mannosyltransferase, ECM39
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223774
Homologene: 36269
Pak2
Name: p21 (RAC1) activated kinase 2
Synonyms: PAK-2, D16Ertd269e, A130002K10Rik, 5330420P17Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224105
HGNC: HGNC:8591
Homologene: 99711
Atp6v1c2
Name: ATPase, H+ transporting, lysosomal V1 subunit C2
Synonyms: 1110038G14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68775
Homologene: 15866
Nlrc4
Name: NLR family, CARD domain containing 4
Synonyms: 9530011P19Rik, Card12, Ipaf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268973
VEGA: 17
Homologene: 10924
Ppp1r3a
Name: protein phosphatase 1, regulatory subunit 3A
Synonyms: GM, RGL
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 140491
HGNC: HGNC:9291
Homologene: 48124
Nav3
Name: neuron navigator 3
Synonyms: Pomfil1p, POMFIL1, 4732483H20Rik, unc53H3, steerin 3, 9630020C08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 260315
Homologene: 56688
Or1p1
Name: olfactory receptor family 1 subfamily P member 1
Synonyms: IH3, MOR133-3P, GA_x6K02T2P1NL-4434429-4435400, Olfr59
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18359
HGNC: HGNC:8222
Homologene: 73924
Capn7
Name: calpain 7
Synonyms: PalBH
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12339
HGNC: HGNC:1484
Homologene: 7651
Zfp790
Name: zinc finger protein 790
Synonyms: 6330581L23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233056
Homologene: 51695
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269356
Homologene: 12931
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Hspb7
Name: heat shock protein family, member 7 (cardiovascular)
Synonyms: cvHsp, Hsp25-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 29818
HGNC: HGNC:5249
Homologene: 8480
Ubqlnl
Name: ubiquilin-like
Synonyms: LOC244179, 4922504M18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244179
Homologene: 17034
Rspo1
Name: R-spondin 1
Synonyms: R-spondin, Rspondin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 192199
Homologene: 52148
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: D030049F17Rik, Nedl2, A730039N16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329152
Homologene: 66192
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Snrpe
Name: small nuclear ribonucleoprotein E
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20643
Homologene: 37729
Bpi
Name: bactericidal permeablility increasing protein
Synonyms: 9230105K17Rik, Bpifd1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329547
HGNC: HGNC:1095
Homologene: 37519
S100a11
Name: S100 calcium binding protein A11
Synonyms: S100c, calgizzarin, cal, Emap1, S100a14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20195
Homologene: 137318
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, 4732458A06Rik, D130016K21Rik, 9430063L05Rik, Usmg4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Lingo2
Name: leucine rich repeat and Ig domain containing 2
Synonyms: B230217C06Rik, Lrrn6c, LERN3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242384
Homologene: 17621
Pappa
Name: pregnancy-associated plasma protein A
Synonyms: PAG1, IGFBP-4ase, PAPP-A, 8430414N03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18491
HGNC: HGNC:8602
Homologene: 31097
Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms: merg1a, ether a go-go related, M-erg, LQT, Lqt2, ERG1, merg1b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16511
HGNC: HGNC:6251
Homologene: 201
Plbd2
Name: phospholipase B domain containing 2
Synonyms: 66.3 kDa, p76, 1300012G16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71772
Homologene: 41528
Gtf2ird2
Name: GTF2I repeat domain containing 2
Synonyms: 1700012P16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 114674
Homologene: 24941
Tmem229a
Name: transmembrane protein 229A
Synonyms: 6332401O19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319832
Homologene: 85312
Or2a56
Name: olfactory receptor family 2 subfamily A member 56
Synonyms: GA_x6K02T2P3E9-4602571-4601639, MOR261-2, Olfr444
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258650
Homologene: 88438
Krba1
Name: KRAB-A domain containing 1
Synonyms: A930040G15Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77827
Homologene: 15880
Vmn2r56
Name: vomeronasal 2, receptor 56
Synonyms: EG629079
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629079
Homologene: 104040
Ube2m
Name: ubiquitin-conjugating enzyme E2M
Synonyms: UBC12, Ubc-rs2, 2510040H03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22192
Homologene: 2952
Grik5
Name: glutamate receptor, ionotropic, kainate 5 (gamma 2)
Synonyms: KA2, GluRgamma2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14809
HGNC: HGNC:4583
Homologene: 1578
Vmn2r73
Name: vomeronasal 2, receptor 73
Synonyms: EG620928
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620928
Homologene: 115466
Or56b34
Name: olfactory receptor family 56 subfamily B member 34
Synonyms: GA_x6K02T2PBJ9-7917168-7918148, MOR40-5, MOR40-16, Olfr688
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259161
Homologene: 128074
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210274
Homologene: 105965
Tmed6
Name: transmembrane p24 trafficking protein 6
Synonyms: 1810018I24Rik, 1810015P03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66269
Homologene: 11938
Rgl3
Name: ral guanine nucleotide dissociation stimulator-like 3
Synonyms: 1300003D20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71746
VEGA: 9
Homologene: 11363
Zpr1
Name: ZPR1 zinc finger
Synonyms: ZPR1, Zfp259
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22687
Homologene: 2900
Ccr3
Name: C-C motif chemokine receptor 3
Synonyms: MIP-1 alphaRL2, CC-CKR3, CKR3, Cmkbr3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12771
VEGA: 9
HGNC: HGNC:1604
Homologene: 20436
Lrrc10
Name: leucine rich repeat containing 10
Synonyms: D330003I11Rik, Hrlrrp, Serdin1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237560
VEGA: 10
Homologene: 17154
Rdh1
Name: retinol dehydrogenase 1 (all trans)
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 107605
Homologene: 129514
Pik3r5
Name: phosphoinositide-3-kinase regulatory subunit 5
Synonyms: Foap2, p101
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 320207
Homologene: 8627
Fmnl1
Name: formin-like 1
Synonyms: 8030453N10Rik, formin-related gene in leukocytes
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 57778
HGNC: HGNC:1212
Homologene: 135620
Rsad2
Name: radical S-adenosyl methionine domain containing 2
Synonyms: Vig1, cig5, 2510004L01Rik, viperin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 58185
Homologene: 10969
Serpina1c
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1C
Synonyms: PI6, PI3, Spi1-3, Spi1-6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20702
HGNC: HGNC:8941
Homologene: 20103
Or5au1
Name: olfactory receptor family 5 subfamily AU member 1
Synonyms: GA_x6K02SYYB8M-929-258, GA_x6K02T2RJGY-959918-960853, MOR205-1, MOR205-2, Olfr1514, Olfr221
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258420
Homologene: 45823
Mgat3
Name: mannoside acetylglucosaminyltransferase 3
Synonyms: GnT-III, 1110038J12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17309
VEGA: 15
HGNC: HGNC:7046
Homologene: 31088
Ccdc134
Name: coiled-coil domain containing 134
Synonyms: 2310042L06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76457
VEGA: 15
Homologene: 77543
Krt18
Name: keratin 18
Synonyms: K18, Endo B, Krt1-18, CK18
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16668
VEGA: 15
HGNC: HGNC:6430
Homologene: 55448
Yipf3
Name: Yip1 domain family, member 3
Synonyms: D17Wsu94e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 28064
Homologene: 9117
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224833
Homologene: 138294
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 53,868,831 bp
  • C to A, chromosome 1 at 74,931,918 bp
  • A to G, chromosome 1 at 133,609,758 bp
  • A to T, chromosome 1 at 190,933,087 bp
  • T to A, chromosome 2 at 28,678,943 bp
  • A to T, chromosome 2 at 60,758,835 bp
  • G to T, chromosome 2 at 130,686,301 bp
  • T to A, chromosome 2 at 158,261,334 bp
  • T to C, chromosome 2 at 158,473,249 bp
  • A to C, chromosome 3 at 86,542,688 bp
  • A to C, chromosome 3 at 93,524,202 bp
  • A to T, chromosome 3 at 95,341,451 bp
  • G to A, chromosome 3 at 97,753,126 bp
  • A to G, chromosome 3 at 151,517,781 bp
  • G to A, chromosome 4 at 35,708,375 bp
  • A to T, chromosome 4 at 65,307,812 bp
  • G to A, chromosome 4 at 124,991,397 bp
  • C to G, chromosome 4 at 130,378,043 bp
  • C to A, chromosome 4 at 130,772,674 bp
  • A to G, chromosome 4 at 141,424,047 bp
  • T to A, chromosome 5 at 24,322,702 bp
  • C to A, chromosome 5 at 36,973,194 bp
  • T to C, chromosome 5 at 81,771,685 bp
  • T to C, chromosome 5 at 107,620,474 bp
  • C to T, chromosome 5 at 120,486,039 bp
  • T to C, chromosome 5 at 134,214,083 bp
  • G to T, chromosome 6 at 14,754,517 bp
  • T to C, chromosome 6 at 24,955,702 bp
  • T to C, chromosome 6 at 42,955,773 bp
  • T to C, chromosome 6 at 48,405,225 bp
  • T to A, chromosome 6 at 77,243,872 bp
  • A to G, chromosome 7 at 12,715,405 bp
  • T to C, chromosome 7 at 13,035,730 bp
  • A to T, chromosome 7 at 25,023,380 bp
  • T to C, chromosome 7 at 29,824,875 bp
  • A to G, chromosome 7 at 30,765,294 bp
  • T to A, chromosome 7 at 85,875,867 bp
  • T to C, chromosome 7 at 104,150,047 bp
  • T to C, chromosome 7 at 105,288,519 bp
  • A to T, chromosome 7 at 144,192,467 bp
  • C to A, chromosome 8 at 23,140,167 bp
  • C to T, chromosome 8 at 107,065,566 bp
  • T to C, chromosome 9 at 20,594,007 bp
  • T to A, chromosome 9 at 21,974,102 bp
  • T to A, chromosome 9 at 46,273,336 bp
  • T to A, chromosome 9 at 64,122,107 bp
  • C to T, chromosome 9 at 124,029,024 bp
  • T to A, chromosome 10 at 94,188,255 bp
  • T to C, chromosome 10 at 109,716,642 bp
  • A to G, chromosome 10 at 117,045,514 bp
  • A to T, chromosome 10 at 121,605,639 bp
  • A to T, chromosome 10 at 127,760,037 bp
  • A to G, chromosome 11 at 59,051,521 bp
  • T to A, chromosome 11 at 68,486,622 bp
  • T to C, chromosome 11 at 74,288,675 bp
  • T to C, chromosome 11 at 87,581,196 bp
  • T to C, chromosome 11 at 103,189,969 bp
  • C to A, chromosome 11 at 121,594,274 bp
  • A to T, chromosome 12 at 9,579,691 bp
  • A to T, chromosome 12 at 17,321,612 bp
  • T to C, chromosome 12 at 26,456,377 bp
  • T to C, chromosome 12 at 103,896,091 bp
  • A to G, chromosome 14 at 31,368,115 bp
  • T to C, chromosome 14 at 52,035,985 bp
  • C to T, chromosome 15 at 80,212,577 bp
  • T to C, chromosome 15 at 81,641,313 bp
  • T to C, chromosome 15 at 82,131,737 bp
  • C to T, chromosome 15 at 88,815,978 bp
  • A to G, chromosome 15 at 98,656,600 bp
  • G to T, chromosome 15 at 102,030,974 bp
  • A to T, chromosome 16 at 32,033,843 bp
  • A to G, chromosome 17 at 46,251,577 bp
  • A to G, chromosome 17 at 47,469,362 bp
  • T to A, chromosome 17 at 56,047,384 bp
  • A to G, chromosome 17 at 74,446,831 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0077 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038364-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.