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Strain Name:
C57BL/6J-MtgxR0189Btlr/Mmmh
Stock Number:
038450-MU
Citation ID:
RRID:MMRRC_038450-MU
Other Names:
R0189 (G1), C57BL/6J-MtgxR0189Btlr
Major Collection:

Strain Information

Kif3c
Name: kinesin family member 3C
Synonyms: N-4 kinesin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16570
VEGA: 12
HGNC: HGNC:6321
Homologene: 55640
Aggf1
Name: angiogenic factor with G patch and FHA domains 1
Synonyms: 2310029P06Rik, VG5Q, 2010009L17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66549
Homologene: 41220
Prpf6
Name: pre-mRNA splicing factor 6
Synonyms: 1190003A07Rik, U5-102K, ANT-1, 2610031L17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68879
Homologene: 5368
Phf20
Name: PHD finger protein 20
Synonyms: 6820402O20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228829
Homologene: 9507
Ranbp1
Name: RAN binding protein 1
Synonyms: Htf9a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19385
HGNC: HGNC:9847
Homologene: 21600
Ahcyl2
Name: S-adenosylhomocysteine hydrolase-like 2
Synonyms: 4631427C17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74340
Homologene: 69337
Tex21
Name: testis expressed gene 21
Synonyms: tsec-2, 4931412D23Rik, 4931406F04Rik, 4931421K24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 80384
VEGA: 12
Homologene: 10510
Zfp101
Name: zinc finger protein 101
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22643
Homologene: 137226
Pola2
Name: polymerase (DNA directed), alpha 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18969
VEGA: 19
Homologene: 48121
Rock2
Name: Rho-associated coiled-coil containing protein kinase 2
Synonyms: Rock-II, B230113H15Rik, Rho-kinase, ROKalpha, Rock2m
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19878
VEGA: 12
Homologene: 21010
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, RA-GEF-2, Pdzgef2, C030018K18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Cstf3
Name: cleavage stimulation factor, 3' pre-RNA, subunit 3
Synonyms: 4732468G05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228410
HGNC: HGNC:2485
Homologene: 1014
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227648
Homologene: 10533
Btbd9
Name: BTB domain containing 9
Synonyms: 1700023F20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224671
VEGA: 17
Homologene: 14995
Dlgap5
Name: DLG associated protein 5
Synonyms: Hurp, C86398, Dlg7
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218977
Homologene: 8840
Mcph1
Name: microcephaly, primary autosomal recessive 1
Synonyms: 5430437K10Rik, BRIT1, D030046N04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244329
HGNC: HGNC:6954
Homologene: 32586
Slc45a4
Name: solute carrier family 45, member 4
Synonyms: 9330175B01Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106068
Homologene: 69908
Slc12a3
Name: solute carrier family 12, member 3
Synonyms: NCC, TSC
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20497
Homologene: 287
Sucla2
Name: succinate-Coenzyme A ligase, ADP-forming, beta subunit
Synonyms: 4930547K18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 20916
Homologene: 2856
Taf6
Name: TATA-box binding protein associated factor 6
Synonyms: p80, Taf2e, 80kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21343
Homologene: 7561
Rnf17
Name: ring finger protein 17
Synonyms: MMIP-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 30054
VEGA: 14
Homologene: 23727
Bcl7c
Name: B cell CLL/lymphoma 7C
Synonyms: C230096E12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12055
HGNC: HGNC:1006
Homologene: 3498
Rgs2
Name: regulator of G-protein signaling 2
Synonyms: GOS8
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19735
HGNC: HGNC:9998
Homologene: 2192
Iqsec3
Name: IQ motif and Sec7 domain 3
Synonyms: BRAG3, synarfGEF
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243621
Homologene: 46091
Ptprc
Name: protein tyrosine phosphatase receptor type C
Synonyms: T200, B220, CD45, Lyt-4, Ly-5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Sun2
Name: Sad1 and UNC84 domain containing 2
Synonyms: B230369L08Rik, Unc84b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223697
Homologene: 9113
Plk2
Name: polo like kinase 2
Synonyms: Snk
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20620
VEGA: 13
Homologene: 21317
Got2
Name: glutamatic-oxaloacetic transaminase 2, mitochondrial
Synonyms: mAspAT, mitochondrial aspartate aminotransferase, FABP-pm, plasma membrane fatty acid binding protein, Kyat4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14719
HGNC: HGNC:4433
Homologene: 1572
Arhgef17
Name: Rho guanine nucleotide exchange factor 17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207212
Homologene: 129601
Med13
Name: mediator complex subunit 13
Synonyms: Trap240, 1110067M05Rik, Thrap1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327987
Homologene: 21067
Dusp3
Name: dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
Synonyms: T-DSP11, VHR, 2210015O03Rik, 5031436O03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72349
HGNC: HGNC:3069
Homologene: 20870
Adam32
Name: a disintegrin and metallopeptidase domain 32
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 353188
Homologene: 17021
Taf9
Name: TATA-box binding protein associated factor 9
Synonyms: 2310012M09Rik, Taf2g
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 108143
Homologene: 39986
Ino80
Name: INO80 complex subunit
Synonyms: 2310079N15Rik, INO80, 4632409L19Rik, Inoc1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68142
Homologene: 75070
Nup54
Name: nucleoporin 54
Synonyms: 3110079L04Rik, 54kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269113
Homologene: 41169
Tubgcp2
Name: tubulin, gamma complex component 2
Synonyms: 1700022B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74237
Homologene: 55980
Nipal3
Name: NIPA-like domain containing 3
Synonyms: 9130020G22Rik, Npal3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74552
Homologene: 10722
Ndfip2
Name: Nedd4 family interacting protein 2
Synonyms: 0710001O20Rik, 9130207N19Rik, N4wbp5a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76273
Homologene: 12636
Eea1
Name: early endosome antigen 1
Synonyms: B230358H09Rik, ZFYVE2, A430109M19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216238
VEGA: 10
HGNC: HGNC:3185
Homologene: 37822
Tnks1bp1
Name: tankyrase 1 binding protein 1
Synonyms: TAB182
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228140
Homologene: 14117
Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
Synonyms: 1810037O03Rik, 9530009M10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329251
HGNC: HGNC:7619
Homologene: 135710
Gprc5b
Name: G protein-coupled receptor, family C, group 5, member B
Synonyms: hypothetical protein, clone 2-63
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 64297
Homologene: 9435
Tac1
Name: tachykinin 1
Synonyms: neurokinin 1, substance P, PPT-A, preprotachykinin A, neurokinin A, Nkna, NK1, 4930528L02Rik, SP, NK-1, PPTA
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21333
Homologene: 2394
Prickle1
Name: prickle planar cell polarity protein 1
Synonyms: 1110058P22Rik, mpk1, b2b019Clo, Pk1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106042
Homologene: 17686
Akap6
Name: A kinase anchor protein 6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Efr3b
Name: EFR3 homolog B
Synonyms: C030014M07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668212
VEGA: 12
Homologene: 66195
Hcn3
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 3
Synonyms: Hac3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15168
Homologene: 22453
Peg12
Name: paternally expressed 12
Synonyms: Frat3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27412
HGNC: HGNC:3944
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Or5b105
Name: olfactory receptor family 5 subfamily B member 105
Synonyms: GA_x6K02T2RE5P-3430689-3429787, MOR202-24, EG667271, Olfr1458
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 667271
HGNC: HGNC:8324
Nanos3
Name: nanos C2HC-type zinc finger 3
Synonyms: nos3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244551
Homologene: 65856
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212392
Homologene: 17668
Abca9
Name: ATP-binding cassette, sub-family A member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Or51ah3
Name: olfactory receptor family 51 subfamily AH member 3
Synonyms: GA_x6K02T2PBJ9-6284902-6285843, MOR19-2, Olfr615
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259084
Homologene: 17494
Adam25
Name: ADAM metallopeptidase domain 25
Synonyms: testase 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23793
HGNC: HGNC:199
Homologene: 128364
Ripk2
Name: receptor (TNFRSF)-interacting serine-threonine kinase 2
Synonyms: CCK, CARDIAK, RIP2, RICK, CARD3, D4Bwg0615e, 2210420D18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 192656
Homologene: 37856
Bbs10
Name: Bardet-Biedl syndrome 10
Synonyms: 1300007O09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71769
VEGA: 10
Homologene: 49781
Tmem184c
Name: transmembrane protein 184C
Synonyms: 8430433H16Rik, Tmem34
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234463
Homologene: 32403
Map3k6
Name: mitogen-activated protein kinase kinase kinase 6
Synonyms: Ask2, MAPKKK6, MEKK6
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 53608
HGNC: HGNC:6858
Homologene: 3435
Or8b56
Name: olfactory receptor family 8 subfamily B member 56
Synonyms: GA_x6K02T2PVTD-32530445-32531380, MOR164-2, Olfr923
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258812
VEGA: 9
Ndufb10
Name: NADH:ubiquinone oxidoreductase subunit B10
Synonyms: 22kDa, 0610011B04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68342
HGNC: HGNC:7696
Homologene: 3343
Or9s14
Name: olfactory receptor family 9 subfamily S member 14
Synonyms: GA_x6K02T2R7CC-81146179-81145211, MOR208-2, Olfr1410
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258484
Homologene: 74205
Tgs1
Name: trimethylguanosine synthase 1
Synonyms: Pimt, D4Ertd800e, Ncoa6ip
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 116940
Homologene: 32608
Trbc2
Name: T cell receptor beta, constant 2
Synonyms: BB153276, Tcrb-C2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100125263
Vmn1r39
Name: vomeronasal 1 receptor 39
Synonyms: Gm5993
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 546903
Homologene: 110800
Rpusd3
Name: RNA pseudouridylate synthase domain containing 3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101122
Homologene: 18342
Vmn1r61
Name: vomeronasal 1 receptor 61
Synonyms: Gm7186
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 636731
Homologene: 41799
Scgb1b20
Name: secretoglobin, family 1B, member 20
Synonyms: Gm7147, Gm5895, Abpa20
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545948
Homologene: 114479
Ccdc83
Name: coiled-coil domain containing 83
Synonyms: 4930549K11Rik, 4930554C01Rik, 4932423M01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75338
Homologene: 32709
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Atxn7l3b
Name: ataxin 7-like 3B
Synonyms: 6230409E21Rik, ENSMUSG00000074747, 4921506J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 382423
Homologene: 115930
Or10p21
Name: olfactory receptor family 10 subfamily P member 21
Synonyms: GA_x6K02T2PULF-10696986-10697915, MOR269-2, Olfr763
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258861
Homologene: 85121
Krt17
Name: keratin 17
Synonyms: K17, Krt1-17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16667
HGNC: HGNC:6427
Homologene: 363
Serpina5
Name: serine (or cysteine) peptidase inhibitor, clade A, member 5
Synonyms: Pci, antitrypsin, alpha-1 antiproteinase, PAI-3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268591
HGNC: HGNC:8723
Homologene: 20159
Has2
Name: hyaluronan synthase 2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15117
HGNC: HGNC:4819
Homologene: 3892
Gfus
Name: GDP-L-fucose synthase
Synonyms: Tstap35b, FX, Tsta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22122
VEGA: 15
Homologene: 2484
Zdhhc14
Name: zinc finger, DHHC domain containing 14
Synonyms: New1cp, B530001K09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224454
VEGA: 17
Homologene: 62301
Msh5
Name: mutS homolog 5
Synonyms: G7, Mut5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Gm18604
Name: predicted gene, 18604
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100417423
Coro1b
Name: coronin, actin binding protein 1B
Synonyms: coronin 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 23789
HGNC: HGNC:2253
Homologene: 40790
Ms4a20
Name: membrane-spanning 4-domains, subfamily A, member 20
Synonyms: 1700017D01Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69369
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 92,607,893 bp
  • A to G, chromosome 1 at 134,865,776 bp
  • G to A, chromosome 1 at 138,082,715 bp
  • T to C, chromosome 1 at 144,002,284 bp
  • T to A, chromosome 2 at 26,424,414 bp
  • A to G, chromosome 2 at 85,070,929 bp
  • A to G, chromosome 2 at 104,652,446 bp
  • T to A, chromosome 2 at 119,379,679 bp
  • A to G, chromosome 2 at 156,303,141 bp
  • T to A, chromosome 2 at 181,655,457 bp
  • T to C, chromosome 3 at 86,368,509 bp
  • T to C, chromosome 3 at 89,148,800 bp
  • A to G, chromosome 4 at 3,593,620 bp
  • A to T, chromosome 4 at 16,129,125 bp
  • G to T, chromosome 4 at 133,246,941 bp
  • A to T, chromosome 4 at 135,468,518 bp
  • T to C, chromosome 5 at 34,616,648 bp
  • A to G, chromosome 5 at 92,422,564 bp
  • T to C, chromosome 5 at 138,182,713 bp
  • C to T, chromosome 6 at 7,562,424 bp
  • A to T, chromosome 6 at 29,891,243 bp
  • T to C, chromosome 6 at 41,548,149 bp
  • T to A, chromosome 6 at 66,805,197 bp
  • C to T, chromosome 6 at 113,415,553 bp
  • A to T, chromosome 6 at 121,413,562 bp
  • T to C, chromosome 7 at 5,610,700 bp
  • G to T, chromosome 7 at 33,373,510 bp
  • G to A, chromosome 7 at 62,463,548 bp
  • T to A, chromosome 7 at 90,226,683 bp
  • G to T, chromosome 7 at 100,928,850 bp
  • G to T, chromosome 7 at 103,561,082 bp
  • T to C, chromosome 7 at 118,983,633 bp
  • G to A, chromosome 7 at 127,705,764 bp
  • A to T, chromosome 7 at 140,001,605 bp
  • T to C, chromosome 8 at 18,788,471 bp
  • T to A, chromosome 8 at 24,922,337 bp
  • T to A, chromosome 8 at 40,755,430 bp
  • T to A, chromosome 8 at 45,935,082 bp
  • C to T, chromosome 8 at 77,597,812 bp
  • C to T, chromosome 8 at 84,176,134 bp
  • C to T, chromosome 8 at 94,356,358 bp
  • T to C, chromosome 8 at 95,888,253 bp
  • T to A, chromosome 9 at 26,883,218 bp
  • T to A, chromosome 9 at 38,827,815 bp
  • T to C, chromosome 10 at 6,789,071 bp
  • G to A, chromosome 10 at 23,941,495 bp
  • A to T, chromosome 10 at 95,995,582 bp
  • T to G, chromosome 10 at 111,301,065 bp
  • A to T, chromosome 10 at 112,928,580 bp
  • T to A, chromosome 10 at 129,011,322 bp
  • C to T, chromosome 11 at 54,691,249 bp
  • A to G, chromosome 11 at 86,319,876 bp
  • A to G, chromosome 11 at 100,260,619 bp
  • A to T, chromosome 11 at 101,981,721 bp
  • A to T, chromosome 11 at 110,108,653 bp
  • A to T, chromosome 11 at 110,141,662 bp
  • T to A, chromosome 12 at 3,365,989 bp
  • T to A, chromosome 12 at 3,982,925 bp
  • T to A, chromosome 12 at 16,959,516 bp
  • T to C, chromosome 12 at 53,141,254 bp
  • T to A, chromosome 12 at 76,239,533 bp
  • T to A, chromosome 12 at 104,103,330 bp
  • A to T, chromosome 13 at 95,356,480 bp
  • A to G, chromosome 13 at 100,655,142 bp
  • C to T, chromosome 13 at 110,399,463 bp
  • T to A, chromosome 14 at 47,412,975 bp
  • A to G, chromosome 14 at 56,482,193 bp
  • T to C, chromosome 14 at 73,592,648 bp
  • T to C, chromosome 14 at 105,304,740 bp
  • A to T, chromosome 15 at 56,668,435 bp
  • A to G, chromosome 15 at 73,581,914 bp
  • C to A, chromosome 15 at 75,926,978 bp
  • C to A, chromosome 15 at 79,737,076 bp
  • A to T, chromosome 15 at 93,503,019 bp
  • A to T, chromosome 16 at 18,241,743 bp
  • T to C, chromosome 17 at 5,725,264 bp
  • T to C, chromosome 17 at 24,724,235 bp
  • C to T, chromosome 17 at 30,274,942 bp
  • T to A, chromosome 17 at 33,382,239 bp
  • T to C, chromosome 17 at 35,029,654 bp
  • T to G, chromosome 17 at 36,229,503 bp
  • T to C, chromosome 19 at 4,153,251 bp
  • A to T, chromosome 19 at 5,942,342 bp
  • A to G, chromosome 19 at 11,096,947 bp
  • G to A, chromosome 19 at 13,103,278 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0189 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038450-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.