Strain Name:
C57BL/6J-MtgxR0302Btlr/Mmmh
Stock Number:
038514-MU
Citation ID:
RRID:MMRRC_038514-MU
Other Names:
R0302 (G1), C57BL/6J-MtgxR0302Btlr
Major Collection:

Gene Information

Kifc3
Name: kinesin family member C3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16582
HGNC: HGNC:6326
Homologene: 124421
Nfat5
Name: nuclear factor of activated T cells 5
Synonyms: nfatz, TonEBP, B130038B15Rik, OREBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54446
HGNC: HGNC:7774
Homologene: 4811
Dnm2
Name: dynamin 2
Synonyms: Dyn2, b2b2159Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13430
HGNC: HGNC:2974
Homologene: 90883
Trim32
Name: tripartite motif-containing 32
Synonyms: 3f3, 1810045E12Rik, Zfp117, BBS11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69807
Homologene: 36327
Slc6a12
Name: solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Synonyms: Gabt2, BGT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14411
Homologene: 128225
Cr1l
Name: complement component (3b/4b) receptor 1-like
Synonyms: mCRY, Crry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12946
HGNC: HGNC:2335
Homologene: 128275
Ints6
Name: integrator complex subunit 6
Synonyms: Notch2l, 2900075H24Rik, DICE1, Ddx26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18130
VEGA: 14
Homologene: 8121
Cbfa2t2
Name: CBFA2/RUNX1 translocation partner 2
Synonyms: MTGR1, C330013D05Rik, Cbfa2t2h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12396
HGNC: HGNC:1536
Homologene: 3733
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Autotaxin, Npps2, PD-Ialpha, Pdnp2, ATX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Asah2
Name: N-acylsphingosine amidohydrolase 2
Synonyms: neutral/alkaline ceramidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 54447
VEGA: 19
Homologene: 10310
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 277854
Homologene: 34718
Mtbp
Name: Mdm2, transformed 3T3 cell double minute p53 binding protein
Synonyms: MDM2BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105837
HGNC: HGNC:7417
Homologene: 11102
Med25
Name: mediator complex subunit 25
Synonyms: ESTM2, 2610529E18Rik, 2610034E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75613
Homologene: 12614
Nsmce4a
Name: NSE4 homolog A, SMC5-SMC6 complex component
Synonyms: 2410003A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67872
Homologene: 9745
Lonp2
Name: lon peptidase 2, peroxisomal
Synonyms: 1300002A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66887
Homologene: 12050
Capza2
Name: capping protein (actin filament) muscle Z-line, alpha 2
Synonyms: Cappa2, 1110053K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12343
HGNC: HGNC:1490
Homologene: 55956
Lrpprc
Name: leucine-rich PPR-motif containing
Synonyms: Lrp130, 3110001K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72416
Homologene: 32695
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: 6720464I07Rik, Solo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223435
VEGA: 15
Homologene: 20847
Taf13
Name: TATA-box binding protein associated factor 13
Synonyms: 2010309N11Rik, 1810004N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99730
Homologene: 4126
Oprl1
Name: opioid receptor-like 1
Synonyms: MOR-C, ORL1, XOR1, LC132, nociceptin/ orphaninFQ receptor, morc, N/OFQ receptor, NOP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18389
HGNC: HGNC:8155
Homologene: 22609
Rnf126
Name: ring finger protein 126
Synonyms: 2610010O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70294
VEGA: 10
Homologene: 27024
Ass1
Name: argininosuccinate synthetase 1
Synonyms: ASS, Ass-1, fold
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11898
HGNC: HGNC:758
Homologene: 6899
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: C530005A01Rik, 6030465E24Rik, spastic paraplegia 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214585
Homologene: 41614
Lypd6
Name: LY6/PLAUR domain containing 6
Synonyms: E130115E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320343
Homologene: 18555
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, Mtap2, repro4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Cyth2
Name: cytohesin 2
Synonyms: CLM2, Pscd2, ARNO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19158
HGNC: HGNC:9502
Homologene: 32116
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 329002
Homologene: 7198
Ttc7b
Name: tetratricopeptide repeat domain 7B
Synonyms: Ttc7l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104718
VEGA: 12
Homologene: 14675
Mctp2
Name: multiple C2 domains, transmembrane 2
Synonyms: LOC244049
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244049
Homologene: 69254
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: Trrp7, LTRPC2, TRPC7, 9830168K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28240
Homologene: 20709
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTP-BL, Ptpri, PTPL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL-19, DLP12, HL19, DHC3, LOC380889, 4921531P07Rik, Dnahc7l, Dnahc12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Man2b1
Name: mannosidase 2, alpha B1
Synonyms: lysosomal alpha-mannosidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17159
HGNC: HGNC:6826
Homologene: 37322
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: fmd, mdg, Cchl1a3, sj, muscle dysgenesis, Cav1.1, DHPR alpha1s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Mfsd6
Name: major facilitator superfamily domain containing 6
Synonyms: 9630025I22Rik, MMR2, 2210010L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98682
Homologene: 9784
Exoc3l
Name: exocyst complex component 3-like
Synonyms: C730015A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 277978
Homologene: 18629
Ankra2
Name: ankyrin repeat, family A (RFXANK-like), 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68558
Homologene: 11312
Olfr1168
Name: olfactory receptor 1168
Synonyms: GA_x6K02T2Q125-49669483-49670421, MOR174-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258524
Homologene: 128091
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Itga1
Name: integrin alpha 1
Synonyms: CD49A, Vla1, E130012M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Ggn
Name: gametogenetin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243897
Homologene: 45139
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Slc2a7
Name: solute carrier family 2 (facilitated glucose transporter), member 7
Synonyms: OTTMUSG00000010396
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435818
Homologene: 72470
Ankdd1a
Name: ankyrin repeat and death domain containing 1A
Synonyms: LOC384945, EG330963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330963
VEGA: 9
Homologene: 65619
Adprs
Name: ADP-ribosylserine hydrolase
Synonyms: Arh3, Adprhl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100206
Homologene: 9863
Ccdc96
Name: coiled-coil domain containing 96
Synonyms: 4921513E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66717
Homologene: 32639
Cckar
Name: cholecystokinin A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12425
HGNC: HGNC:1570
Homologene: 37337
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216188
Homologene: 51942
Cpt1b
Name: carnitine palmitoyltransferase 1b, muscle
Synonyms: M-CPTI, M-CPT I, Cpt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12895
HGNC: HGNC:2329
Homologene: 22548
Lcn2
Name: lipocalin 2
Synonyms: 24p3, NGAL, NRL, neu-related lipocalin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16819
HGNC: HGNC:6526
Homologene: 4064
Pbx3
Name: pre B cell leukemia homeobox 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18516
HGNC: HGNC:8634
Homologene: 21243
Nr1h3
Name: nuclear receptor subfamily 1, group H, member 3
Synonyms: LXR alpha, Unr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22259
HGNC: HGNC:7966
Homologene: 21165
Vmn1r184
Name: vomeronasal 1 receptor, 184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100312477
Homologene: 74353
Mtmr10
Name: myotubularin related protein 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233315
Homologene: 9822
Zfr2
Name: zinc finger RNA binding protein 2
Synonyms: 2010013I23Rik, 9130206N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103406
Homologene: 88124
Ccl4
Name: chemokine (C-C motif) ligand 4
Synonyms: MIP-1B, MIP-1 beta, Mip1b, Scya4, AT744.1, Act-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20303
Homologene: 48153
Krt23
Name: keratin 23
Synonyms: K23, CK23, Krt1-23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94179
HGNC: HGNC:6438
Homologene: 9172
Fam75d3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Epsti1
Name: epithelial stromal interaction 1 (breast)
Synonyms: 5033415K03Rik, BRESI1, 2310046K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 108670
VEGA: 14
Homologene: 12630
Lrrc14
Name: leucine rich repeat containing 14
Synonyms: E130306I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223664
Homologene: 40970
Il1rap
Name: interleukin 1 receptor accessory protein
Synonyms: IL-1R AcP, IL-1RAcP, 6430709H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16180
HGNC: HGNC:5995
Homologene: 1643
Daxx
Name: Fas death domain-associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13163
HGNC: HGNC:2681
Homologene: 1033
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 46,123,777 bp
  • T to C, chromosome 1 at 52,709,457 bp
  • A to T, chromosome 1 at 66,414,828 bp
  • A to T, chromosome 1 at 105,589,093 bp
  • A to G, chromosome 1 at 136,100,604 bp
  • G to A, chromosome 1 at 195,117,793 bp
  • A to T, chromosome 2 at 31,514,819 bp
  • A to G, chromosome 2 at 32,384,889 bp
  • A to T, chromosome 2 at 34,224,560 bp
  • T to G, chromosome 2 at 50,165,667 bp
  • T to A, chromosome 2 at 88,185,510 bp
  • A to G, chromosome 2 at 91,192,013 bp
  • G to A, chromosome 2 at 112,647,123 bp
  • A to T, chromosome 2 at 122,092,187 bp
  • T to C, chromosome 2 at 154,534,876 bp
  • G to A, chromosome 2 at 181,719,228 bp
  • A to G, chromosome 3 at 108,571,722 bp
  • G to A, chromosome 4 at 65,613,254 bp
  • T to C, chromosome 4 at 126,317,392 bp
  • C to T, chromosome 4 at 150,149,521 bp
  • T to C, chromosome 5 at 32,904,546 bp
  • A to T, chromosome 5 at 36,486,101 bp
  • GCTTAGCCTCTTCT to GCT, chromosome 5 at 53,700,299 bp
  • G to T, chromosome 5 at 103,565,225 bp
  • G to A, chromosome 6 at 17,648,524 bp
  • A to G, chromosome 6 at 121,363,259 bp
  • A to T, chromosome 7 at 26,267,543 bp
  • G to T, chromosome 7 at 29,171,240 bp
  • A to C, chromosome 7 at 44,880,558 bp
  • C to A, chromosome 7 at 45,810,585 bp
  • A to T, chromosome 7 at 64,297,497 bp
  • C to T, chromosome 7 at 72,090,264 bp
  • A to G, chromosome 7 at 130,545,893 bp
  • A to G, chromosome 8 at 85,093,016 bp
  • A to G, chromosome 8 at 86,637,991 bp
  • G to T, chromosome 8 at 95,103,470 bp
  • C to T, chromosome 8 at 105,293,543 bp
  • T to C, chromosome 8 at 107,358,701 bp
  • G to T, chromosome 9 at 21,500,343 bp
  • G to A, chromosome 9 at 65,509,642 bp
  • A to C, chromosome 10 at 77,943,990 bp
  • G to T, chromosome 10 at 79,759,223 bp
  • G to T, chromosome 10 at 81,251,336 bp
  • G to A, chromosome 10 at 83,520,365 bp
  • T to A, chromosome 11 at 83,663,454 bp
  • A to G, chromosome 11 at 99,478,201 bp
  • T to C, chromosome 12 at 100,387,179 bp
  • T to C, chromosome 13 at 59,703,150 bp
  • T to A, chromosome 13 at 98,271,692 bp
  • G to A, chromosome 13 at 115,012,318 bp
  • A to G, chromosome 14 at 26,799,999 bp
  • T to C, chromosome 14 at 62,709,512 bp
  • A to T, chromosome 14 at 77,939,926 bp
  • A to G, chromosome 15 at 27,902,517 bp
  • T to C, chromosome 15 at 54,860,061 bp
  • A to T, chromosome 15 at 55,625,424 bp
  • G to T, chromosome 15 at 76,714,352 bp
  • A to G, chromosome 15 at 89,417,870 bp
  • A to G, chromosome 16 at 26,692,794 bp
  • G to T, chromosome 16 at 91,656,144 bp
  • T to A, chromosome 17 at 33,913,620 bp
  • T to C, chromosome 17 at 84,740,078 bp
  • T to C, chromosome 18 at 82,658,088 bp
  • A to T, chromosome 19 at 32,052,956 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0302 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038514-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.