Strain Name:
C57BL/6J-MtgxR0382Btlr/Mmmh
Stock Number:
038588-MU
Citation ID:
RRID:MMRRC_038588-MU
Other Names:
R0382 (G1), C57BL/6J-MtgxR0382Btlr
Major Collection:

Gene Information

Vps41
Name: VPS41 HOPS complex subunit
Synonyms: Vam2, mVam2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218035
VEGA: 13
Homologene: 69165
Ckm
Name: creatine kinase, muscle
Synonyms: Ckmm, MCK, M-CK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12715
HGNC: HGNC:1994
Homologene: 20432
Ptprf
Name: protein tyrosine phosphatase, receptor type, F
Synonyms: RPTP-LAR, LAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: 2810449C13Rik, D330022K21Rik, Usp31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 170707
Homologene: 12988
Gstcd
Name: glutathione S-transferase, C-terminal domain containing
Synonyms: 4933434L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67553
Homologene: 11693
Trpc4ap
Name: transient receptor potential cation channel, subfamily C, member 4 associated protein
Synonyms: D2Ertd113e, Trrp4ap, Trp4-associated protein TAP1, 4833429F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56407
Homologene: 9224
Utp4
Name: UTP4 small subunit processome component
Synonyms: Cirh1a, Tex292, TEG-292
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 21771
HGNC: HGNC:1983
Homologene: 40775
Tmem39a
Name: transmembrane protein 39a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67846
Homologene: 9985
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: ska26, skax26, Cd, skam26Jus
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Slc22a3
Name: solute carrier family 22 (organic cation transporter), member 3
Synonyms: Oct3, Orct3, EMT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20519
VEGA: 17
Homologene: 22630
Fnbp1l
Name: formin binding protein 1-like
Synonyms: 2610318I01Rik, TOCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214459
Homologene: 134636
Clec14a
Name: C-type lectin domain family 14, member a
Synonyms: 1200003C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 66864
VEGA: 12
Homologene: 12047
Fstl3
Name: follistatin-like 3
Synonyms: E030038F23Rik, Flrg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 83554
HGNC: HGNC:3973
Homologene: 4280
Aak1
Name: AP2 associated kinase 1
Synonyms: D6Ertd245e, 5530400K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 269774
Homologene: 128746
Patl1
Name: protein associated with topoisomerase II homolog 1 (yeast)
Synonyms: Pat1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225929
VEGA: 19
Homologene: 82269
Rbm45
Name: RNA binding motif protein 45
Synonyms: Drb1, G430095G15Rik, Drbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241490
Homologene: 15560
Strbp
Name: spermatid perinuclear RNA binding protein
Synonyms: 6430510M02Rik, C230082I21Rik, Spnr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20744
Homologene: 7548
Mov10l1
Name: Mov10 like RISC complex RNA helicase 1
Synonyms: Csm, CHAMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 83456
HGNC: HGNC:7201
Homologene: 56835
Natd1
Name: N-acetyltransferase domain containing 1
Synonyms: Gtlf3b, Gm16515, F3-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 24083
Homologene: 11907
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268379
Homologene: 27991
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E21Rik, 2310076E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76469
VEGA: 13
Homologene: 137367
Fat3
Name: FAT atypical cadherin 3
Synonyms: D430038H04Rik, LOC234973, 9430076A06Rik, LOC382129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270120
VEGA: 9
Homologene: 82252
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, Dnahc17, 2810003K23Rik, Dnahcl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Slc9b2
Name: solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
Synonyms: C80638, NHE10, Nhedc2, nha-oc, NHA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 97086
Homologene: 45381
Efcab7
Name: EF-hand calcium binding domain 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230500
Homologene: 19952
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Usp50
Name: ubiquitin specific peptidase 50
Synonyms: 1700086G18Rik, 4930511O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75083
Homologene: 75281
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245026
Homologene: 18260
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237887
Dcaf12
Name: DDB1 and CUL4 associated factor 12
Synonyms: 1500001L20Rik, 5830424K06Rik, Wdr40a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68970
Homologene: 49418
Gpatch1
Name: G patch domain containing 1
Synonyms: Gpatc1, 1300003A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67471
Homologene: 41217
Stox2
Name: storkhead box 2
Synonyms: 4933409N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 71069
Homologene: 18414
Sgsm3
Name: small G protein signaling modulator 3
Synonyms: 1810012I01Rik, Rutbc3, CIP85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105835
Homologene: 9249
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Adgrc3, flamingo, Fmi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Vmn2r9
Name: vomeronasal 2, receptor 9
Synonyms: EG435864
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 435864
Homologene: 129606
Adap2
Name: ArfGAP with dual PH domains 2
Synonyms: centaurin alpha 2, Centa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216991
Homologene: 10179
Cttnbp2
Name: cortactin binding protein 2
Synonyms: ORF4, 3010022N24Rik, Cortbp2, 4732477G22Rik, 9130022E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30785
Homologene: 14125
Rad21l
Name: RAD21-like (S. pombe)
Synonyms: Gm14160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668929
Homologene: 82650
Tcam1
Name: testicular cell adhesion molecule 1
Synonyms: 4930570F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75870
Homologene: 123944
Olfr1354
Name: olfactory receptor 1354
Synonyms: MOR139-5, GA_x6K02T03FR9-4826-3919, EG257869, MOR139-7, Olfr233-ps1, GA_x6K02T2QGN0-2895081-2894349, MOR185-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 259163
Homologene: 136441
Slfn8
Name: schlafen 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 276950
Homologene: 45432
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: Nhe9, 5730527A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 331004
Homologene: 69753
Uap1
Name: UDP-N-acetylglucosamine pyrophosphorylase 1
Synonyms: SPAG2, ESTM38, AgX, AGX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 107652
Homologene: 2342
Olfr1052
Name: olfactory receptor 1052
Synonyms: GA_x6K02T2Q125-47777498-47778436, MOR172-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259012
Homologene: 79679
Olfr1183
Name: olfactory receptor 1183
Synonyms: GA_x6K02T2Q125-49948903-49949814, MOR230-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258522
Homologene: 128125
Gm8775
Name: predicted gene 8775
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100417855
Qrfpr
Name: pyroglutamylated RFamide peptide receptor
Synonyms: Gpr103, AQ27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229214
Homologene: 18865
Brinp1
Name: bone morphogenic protein/retinoic acid inducible neural specific 1
Synonyms: Dbccr1, Dbc1, Fam5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56710
HGNC: HGNC:2687
Homologene: 8754
P2rx2
Name: purinergic receptor P2X, ligand-gated ion channel, 2
Synonyms: P2X2a, P2x2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231602
Homologene: 14251
Fbxl14
Name: F-box and leucine-rich repeat protein 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101358
Homologene: 15271
Vmn2r45
Name: vomeronasal 2, receptor 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100042810
Homologene: 113703
Vmn1r94
Name: vomeronasal 1 receptor 94
Synonyms: Gm6160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620537
Homologene: 104166
Klk6
Name: kallikrein related-peptidase 6
Synonyms: Prss18, Prss9, neurosin, protease M, Bssp, Klk29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 19144
HGNC: HGNC:6367
Homologene: 68279
Rnf170
Name: ring finger protein 170
Synonyms: 6720407G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 77733
Homologene: 12807
Ces1b
Name: carboxylesterase 1B
Synonyms: Gm5158
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382044
HGNC: HGNC:1863
Homologene: 117484
Lztfl1
Name: leucine zipper transcription factor-like 1
Synonyms: 5530402H04Rik, 6130400H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 93730
HGNC: HGNC:6741
Homologene: 41368
Fbxo5
Name: F-box protein 5
Synonyms: Emi1, 2510044I10Rik, Fbxo31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67141
Homologene: 8135
Olfr792
Name: olfactory receptor 792
Synonyms: GA_x6K02T2PULF-11219415-11220350, MOR108-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258150
Homologene: 133881
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 170,161,482 bp
  • A to T, chromosome 2 at 37,600,826 bp
  • T to A, chromosome 2 at 76,370,211 bp
  • A to G, chromosome 2 at 86,298,593 bp
  • A to T, chromosome 2 at 88,461,725 bp
  • T to A, chromosome 2 at 126,777,928 bp
  • A to T, chromosome 2 at 151,645,443 bp
  • A to G, chromosome 2 at 155,636,230 bp
  • T to A, chromosome 3 at 4,212,073 bp
  • C to T, chromosome 3 at 36,180,969 bp
  • A to T, chromosome 3 at 122,570,953 bp
  • A to T, chromosome 3 at 132,986,408 bp
  • G to T, chromosome 3 at 135,318,422 bp
  • T to C, chromosome 4 at 41,302,672 bp
  • T to C, chromosome 4 at 68,762,308 bp
  • T to C, chromosome 4 at 99,901,769 bp
  • A to G, chromosome 4 at 118,223,394 bp
  • C to G, chromosome 4 at 130,007,831 bp
  • A to G, chromosome 4 at 137,621,218 bp
  • T to C, chromosome 5 at 108,847,597 bp
  • T to A, chromosome 5 at 110,341,179 bp
  • A to G, chromosome 6 at 18,435,343 bp
  • A to T, chromosome 6 at 86,946,919 bp
  • T to C, chromosome 6 at 119,481,060 bp
  • A to G, chromosome 6 at 134,467,668 bp
  • T to G, chromosome 7 at 8,483,099 bp
  • T to C, chromosome 7 at 19,421,384 bp
  • A to T, chromosome 7 at 20,167,653 bp
  • T to C, chromosome 7 at 35,301,655 bp
  • A to G, chromosome 7 at 43,829,245 bp
  • A to T, chromosome 8 at 26,125,899 bp
  • A to G, chromosome 8 at 47,203,284 bp
  • T to C, chromosome 8 at 93,076,052 bp
  • T to C, chromosome 8 at 106,922,935 bp
  • A to G, chromosome 9 at 15,959,756 bp
  • A to T, chromosome 9 at 94,685,217 bp
  • T to A, chromosome 9 at 105,755,555 bp
  • C to A, chromosome 9 at 108,829,218 bp
  • T to C, chromosome 9 at 123,707,906 bp
  • G to T, chromosome 10 at 5,801,176 bp
  • T to A, chromosome 10 at 78,917,126 bp
  • T to C, chromosome 10 at 79,777,307 bp
  • T to C, chromosome 10 at 129,541,014 bp
  • T to C, chromosome 11 at 9,636,650 bp
  • T to C, chromosome 11 at 59,040,306 bp
  • C to T, chromosome 11 at 60,906,913 bp
  • T to C, chromosome 11 at 80,178,385 bp
  • T to A, chromosome 11 at 83,004,556 bp
  • T to A, chromosome 11 at 83,029,534 bp
  • G to A, chromosome 11 at 106,284,078 bp
  • T to C, chromosome 11 at 118,128,996 bp
  • A to G, chromosome 12 at 58,268,617 bp
  • C to A, chromosome 13 at 18,827,727 bp
  • A to T, chromosome 13 at 93,092,748 bp
  • G to A, chromosome 15 at 81,008,314 bp
  • A to G, chromosome 15 at 88,985,593 bp
  • A to G, chromosome 16 at 38,591,398 bp
  • C to T, chromosome 17 at 12,421,507 bp
  • T to A, chromosome 19 at 11,925,232 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0382 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038588-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.