Strain Name:
C57BL/6J-MtgxR0449Btlr/Mmmh
Stock Number:
038649-MU
Citation ID:
RRID:MMRRC_038649-MU
Other Names:
R0449 (G1), C57BL/6J-MtgxR0449Btlr
Major Collection:

Gene Information

Il4
Name: interleukin 4
Synonyms: Il-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16189
HGNC: HGNC:6014
Homologene: 491
Cops3
Name: COP9 signalosome subunit 3
Synonyms: Sgn3, COP9 complex S3, Csn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26572
HGNC: HGNC:2239
Homologene: 2710
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Top1
Name: topoisomerase (DNA) I
Synonyms: Top-1, D130064I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21969
Homologene: 2467
Dtnb
Name: dystrobrevin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13528
HGNC: HGNC:3058
Homologene: 74875
Efr3a
Name: EFR3 homolog A
Synonyms: A130089M23Rik, D030063F01Rik, C920006C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76740
Homologene: 44222
Barhl1
Name: BarH like homeobox 1
Synonyms: Dres115, MBH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54422
HGNC: HGNC:953
Homologene: 81871
Slk
Name: STE20-like kinase
Synonyms: 9A2, mSLK, Etk4, SLK, Stk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20874
Homologene: 22515
Cdyl2
Name: chromodomain protein, Y chromosome-like 2
Synonyms: 1700029M19Rik, 4930453I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75796
Homologene: 41779
L3mbtl2
Name: L3MBTL2 polycomb repressive complex 1 subunit
Synonyms: 4732493N06Rik, m4mbt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 214669
Homologene: 12882
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216860
Homologene: 13029
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: GCN1L, G431004K08Rik, Gcn1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Tubgcp5
Name: tubulin, gamma complex associated protein 5
Synonyms: GCP5, B130010C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233276
Homologene: 14172
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: RPC155, RPC1, 9330175N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218832
VEGA: 14
Homologene: 5124
Ints4
Name: integrator complex subunit 4
Synonyms: 2610034N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101861
Homologene: 69427
Ddx46
Name: DEAD box helicase 46
Synonyms: 2200005K02Rik, 8430438J23Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 212880
VEGA: 13
Homologene: 5430
Fasn
Name: fatty acid synthase
Synonyms: FAS, A630082H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Serpini1
Name: serine (or cysteine) peptidase inhibitor, clade I, member 1
Synonyms: Neuroserpin, PI12, Spi17, Ns
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20713
HGNC: HGNC:8943
Homologene: 21045
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Ctnnd1
Name: catenin (cadherin associated protein), delta 1
Synonyms: P120, Ctnnd, p120-catenin, Catns
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12388
HGNC: HGNC:2515
Homologene: 1017
Vars
Name: valyl-tRNA synthetase
Synonyms: G7a, D17H6S56E, Bat-6, Bat6, Vars2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22321
Homologene: 4587
Tlr4
Name: toll-like receptor 4
Synonyms: Lps, Rasl2-8, lipopolysaccharide response
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21898
Homologene: 41317
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66725
Homologene: 18982
Ankrd13c
Name: ankyrin repeat domain 13c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433667
Homologene: 41804
Gm9631
Name: predicted gene 9631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 674842
VEGA: 11
Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Synonyms: Plekhe1, Phlpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98432
Homologene: 11015
Rfx7
Name: regulatory factor X, 7
Synonyms: 2510005N23Rik, 9930116O05Rik, D130086K05Rik, Rfxdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319758
Homologene: 11275
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 623474
Homologene: 8240
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269700
Homologene: 28297
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71169
VEGA: 12
Homologene: 41073
Slurp2
Name: secreted Ly6/Plaur domain containing 2
Synonyms: 2300005B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69462
Homologene: 104043
Krt14
Name: keratin 14
Synonyms: epidermolysis bullosa simplex, Dowling-Meara, Koebner, Krt-1.14, K14, Cytokeratin 14, Krt1-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16664
HGNC: HGNC:6416
Homologene: 110439
Zyx
Name: zyxin
Synonyms: R75157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22793
Homologene: 31164
Myo15
Name: myosin XV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Zbed5
Name: zinc finger, BED type containing 5
Synonyms: 2410018M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71970
Homologene: 84838
Abcb4
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Synonyms: mdr-2, Mdr2, Pgy-2, Pgy2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Pigg
Name: phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms: Gpi7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433931
Homologene: 39421
Xylt2
Name: xylosyltransferase II
Synonyms: E030002B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217119
Homologene: 23349
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: B930001P07Rik, 6330504P12Rik, MLSN2, melastatin 2, LTRPC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226025
VEGA: 19
Homologene: 62287
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: ALX, Hsh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209488
Homologene: 13142
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 192190
Homologene: 16332
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Mi-2 alpha, Prp9-1, Prp7, 2600010P09Rik, Chd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Ints11
Name: integrator complex subunit 11
Synonyms: 2410006F12Rik, Cpsf3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71957
Homologene: 9894
Slc45a1
Name: solute carrier family 45, member 1
Synonyms: Dnb5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242773
Homologene: 44908
Ptprh
Name: protein tyrosine phosphatase, receptor type, H
Synonyms: SAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 545902
HGNC: HGNC:9672
Homologene: 37693
Dclk1
Name: doublecortin-like kinase 1
Synonyms: CPG16, DCLK, 1700113D08Rik, 2810480F11Rik, Dcl, Click-I, Dcamkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Gpr75
Name: G protein-coupled receptor 75
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237716
HGNC: HGNC:4526
Homologene: 4945
Zfp53
Name: zinc finger protein 53
Synonyms: zfas8, KRAZ1, Zfp-53, Zfp118, D030067O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 24132
VEGA: 17
Homologene: 135946
Mrpl21
Name: mitochondrial ribosomal protein L21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 353242
Homologene: 32936
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69700
Homologene: 43567
Krt81
Name: keratin 81
Synonyms: Krt2-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64818
VEGA: 15
HGNC: HGNC:6458
Homologene: 55645
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Ccdc81
Name: coiled-coil domain containing 81
Synonyms: 4921513D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70884
Homologene: 128447
Slc27a6
Name: solute carrier family 27 (fatty acid transporter), member 6
Synonyms: FATP6, 4732438L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225579
Homologene: 38385
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Hsf4
Name: heat shock transcription factor 4
Synonyms: ldis1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26386
HGNC: HGNC:5227
Homologene: 100128
Pramel17
Name: PRAME like 17
Synonyms: B020004J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545662
Homologene: 128627
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Klk1b11
Name: kallikrein 1-related peptidase b11
Synonyms: mGK-11, Klk11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16613
HGNC: HGNC:6364
Homologene: 68141
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237711
Homologene: 104282
Olfr829
Name: olfactory receptor 829
Synonyms: GA_x6K02T2PVTD-12599710-12600648, MOR147-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 259070
Homologene: 138324
Msh5
Name: mutS homolog 5
Synonyms: G7, Mut5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17687
HGNC: HGNC:7328
Homologene: 8415
Bag6
Name: BCL2-associated athanogene 6
Synonyms: D17H6S52E, G3, 2410045D21Rik, Scythe, Bat3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224727
Homologene: 3409
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277360
Homologene: 10821
Fbxl6
Name: F-box and leucine-rich repeat protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 30840
VEGA: 15
Homologene: 8130
Fam83c
Name: family with sequence similarity 83, member C
Synonyms: 5530400B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71405
Homologene: 18669
Adam29
Name: a disintegrin and metallopeptidase domain 29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244486
HGNC: HGNC:207
Homologene: 8607
Accsl
Name: 1-aminocyclopropane-1-carboxylate synthase (non-functional)-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381411
Homologene: 86007
Zfp937
Name: zinc finger protein 937
Synonyms: Gm4979
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 245174
Homologene: 136215
Olfr850
Name: olfactory receptor 850
Synonyms: GA_x6K02T2PVTD-13214162-13213224, MOR147-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258516
Homologene: 121552
Olfr16
Name: olfactory receptor 16
Synonyms: MOR23, MOR267-13, GA_x6K02T2R7CC-893157-892228
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18313
Homologene: 7460
Cst10
Name: cystatin 10 (chondrocytes)
Synonyms: DD72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58214
HGNC: HGNC:2477
Homologene: 55615
Rbm12b1
Name: RNA binding motif protein 12 B1
Synonyms: 3000004N20Rik, Rbm12b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72397
Homologene: 28658
Bend4
Name: BEN domain containing 4
Synonyms: EG666938, D330027G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 666938
Homologene: 52626
Slc35f2
Name: solute carrier family 35, member F2
Synonyms: 1500009K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72022
VEGA: 9
Homologene: 36363
Gpr182
Name: G protein-coupled receptor 182
Synonyms: Gpcr22, Gpcr17, NOW, G10-D, AM-R, Admr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11536
Homologene: 5255
Olfr782
Name: olfactory receptor 782
Synonyms: GA_x6K02T2PULF-11031172-11032116, MOR110-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 257985
Homologene: 133581
Olfr179
Name: olfactory receptor 179
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
CN725425
Name: cDNA sequence CN725425
Synonyms: Gm5807
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 545126
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 106,350,578 bp
  • T to A, chromosome 1 at 172,957,398 bp
  • C to T, chromosome 2 at 28,915,292 bp
  • G to T, chromosome 2 at 84,603,262 bp
  • T to A, chromosome 2 at 93,866,074 bp
  • T to A, chromosome 2 at 119,941,381 bp
  • T to A, chromosome 2 at 149,407,398 bp
  • G to T, chromosome 2 at 150,239,546 bp
  • T to A, chromosome 2 at 155,830,295 bp
  • C to T, chromosome 2 at 160,712,708 bp
  • A to G, chromosome 2 at 166,569,377 bp
  • T to C, chromosome 3 at 55,500,020 bp
  • A to G, chromosome 3 at 75,613,341 bp
  • A to G, chromosome 3 at 157,991,714 bp
  • T to A, chromosome 4 at 11,606,131 bp
  • A to G, chromosome 4 at 12,145,507 bp
  • A to C, chromosome 4 at 66,839,620 bp
  • T to C, chromosome 4 at 101,836,961 bp
  • A to C, chromosome 4 at 150,643,305 bp
  • G to T, chromosome 4 at 155,887,948 bp
  • A to T, chromosome 5 at 8,939,885 bp
  • T to C, chromosome 5 at 67,398,240 bp
  • T to C, chromosome 5 at 108,336,411 bp
  • T to C, chromosome 5 at 115,592,057 bp
  • G to A, chromosome 5 at 121,364,590 bp
  • G to A, chromosome 5 at 129,901,726 bp
  • T to A, chromosome 6 at 42,351,313 bp
  • C to T, chromosome 6 at 48,466,740 bp
  • T to A, chromosome 7 at 4,598,006 bp
  • G to A, chromosome 7 at 43,997,792 bp
  • C to T, chromosome 7 at 55,823,567 bp
  • T to C, chromosome 7 at 89,890,471 bp
  • G to A, chromosome 7 at 97,529,223 bp
  • C to T, chromosome 8 at 55,872,681 bp
  • G to A, chromosome 8 at 72,200,460 bp
  • A to G, chromosome 8 at 105,275,590 bp
  • A to G, chromosome 8 at 116,583,192 bp
  • T to C, chromosome 9 at 18,856,649 bp
  • T to A, chromosome 9 at 19,478,092 bp
  • G to T, chromosome 9 at 53,816,917 bp
  • A to T, chromosome 9 at 72,610,304 bp
  • C to A, chromosome 10 at 88,540,960 bp
  • A to G, chromosome 10 at 127,750,696 bp
  • A to G, chromosome 10 at 129,351,234 bp
  • A to C, chromosome 11 at 29,893,213 bp
  • A to G, chromosome 11 at 30,892,456 bp
  • A to T, chromosome 11 at 53,618,605 bp
  • A to C, chromosome 11 at 58,665,963 bp
  • A to G, chromosome 11 at 59,818,417 bp
  • G to A, chromosome 11 at 60,509,596 bp
  • C to A, chromosome 11 at 69,357,541 bp
  • T to C, chromosome 11 at 69,905,567 bp
  • A to G, chromosome 11 at 94,666,333 bp
  • G to T, chromosome 11 at 94,668,246 bp
  • C to A, chromosome 11 at 100,207,395 bp
  • T to C, chromosome 11 at 120,811,068 bp
  • A to T, chromosome 11 at 121,943,251 bp
  • C to T, chromosome 12 at 3,591,971 bp
  • T to A, chromosome 12 at 13,519,108 bp
  • T to C, chromosome 12 at 59,172,594 bp
  • T to C, chromosome 13 at 55,653,088 bp
  • A to T, chromosome 14 at 24,484,466 bp
  • T to C, chromosome 15 at 34,428,541 bp
  • T to G, chromosome 15 at 44,501,519 bp
  • T to A, chromosome 15 at 65,842,704 bp
  • A to G, chromosome 15 at 71,962,671 bp
  • G to A, chromosome 15 at 74,743,106 bp
  • A to G, chromosome 15 at 76,535,955 bp
  • C to T, chromosome 15 at 81,668,741 bp
  • G to T, chromosome 15 at 91,238,944 bp
  • T to C, chromosome 15 at 91,750,275 bp
  • C to A, chromosome 15 at 101,463,627 bp
  • A to T, chromosome 16 at 89,837,827 bp
  • C to T, chromosome 17 at 21,508,833 bp
  • T to G, chromosome 17 at 35,012,727 bp
  • T to A, chromosome 17 at 35,041,482 bp
  • T to G, chromosome 17 at 35,141,466 bp
  • A to C, chromosome 17 at 74,692,295 bp
  • A to G, chromosome 18 at 12,500,512 bp
  • T to G, chromosome 18 at 58,609,165 bp
  • T to A, chromosome 19 at 3,292,459 bp
  • T to A, chromosome 19 at 22,988,054 bp
  • T to A, chromosome 19 at 47,637,411 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0449 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038649-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.