Strain Name:
C57BL/6J-MtgxR0464Btlr/Mmmh
Stock Number:
038664-MU
Citation ID:
RRID:MMRRC_038664-MU
Other Names:
R0464 (G1), C57BL/6J-MtgxR0464Btlr
Major Collection:

Gene Information

Sbf2
Name: SET binding factor 2
Synonyms: Mtmr13, mMTMH1, 4833411B01Rik, B430219L04Rik, SBF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Pik3cb
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Synonyms: p110beta, 1110001J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74769
HGNC: HGNC:8976
Homologene: 21250
Kcnj5
Name: potassium inwardly-rectifying channel, subfamily J, member 5
Synonyms: GIRK4, Kir3.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16521
VEGA: 9
HGNC: HGNC:6266
Homologene: 20248
Styx
Name: serine/threonine/tyrosine interaction protein
Synonyms: STNS (alternatively spliced intron of Styx), 0610039A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56291
VEGA: 14
Homologene: 41331
Gprc5a
Name: G protein-coupled receptor, family C, group 5, member A
Synonyms: Raig1, Rai3, Gprc5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232431
HGNC: HGNC:9836
Homologene: 2961
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 4930432B04Rik, D730027C18Rik, 3110043H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75786
Homologene: 8844
Wwp1
Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: 8030445B08Rik, SDRP1, Tiul1, AIP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 107568
Homologene: 21385
Triobp
Name: TRIO and F-actin binding protein
Synonyms: EST478828, Mus EST 478828, Tara
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110253
Homologene: 5104
Nf1
Name: neurofibromin 1
Synonyms: Mhdadsk9, Nf-1, Dsk9, neurofibromin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Safb
Name: scaffold attachment factor B
Synonyms: 5330423C17Rik, 3110021E02Rik, SAFB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224903
Homologene: 2229
G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: GAP SH3 binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27041
Homologene: 38096
Srbd1
Name: S1 RNA binding domain 1
Synonyms: D530025C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78586
VEGA: 17
Homologene: 9994
Ubxn4
Name: UBX domain protein 4
Synonyms: 1300013G12Rik, Ubxd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67812
Homologene: 40962
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Nek1
Name: NIMA (never in mitosis gene a)-related expressed kinase 1
Synonyms: kidney, anemia and testis, kat, D8Ertd790e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18004
HGNC: HGNC:7744
Homologene: 14376
Ncbp3
Name: nuclear cap binding subunit 3
Synonyms: 1200014J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66874
Homologene: 10231
Sgo2a
Name: shugoshin 2A
Synonyms: Tripin, 5730576N04Rik, Sgol2a, D1Ertd8e, 1110007N04Rik, Sgol2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68549
Homologene: 51867
Atp5a1
Name: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Synonyms: D18Ertd206e, Mom2, Atpm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11946
HGNC: HGNC:823
Homologene: 2985
Trh
Name: thyrotropin releasing hormone
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22044
Homologene: 5163
Kcnn2
Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Synonyms: SK2, fri, small conductance calcium-activated potassium channel 2, bc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 140492
HGNC: HGNC:6291
Homologene: 135651
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: SPT6, 5131400N11Rik, Supt6h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20926
Homologene: 40661
Glt8d2
Name: glycosyltransferase 8 domain containing 2
Synonyms: 1110021D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74782
Homologene: 41826
Lypd6
Name: LY6/PLAUR domain containing 6
Synonyms: E130115E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320343
Homologene: 18555
Gna15
Name: guanine nucleotide binding protein, alpha 15
Synonyms: G[a]15, Galpha15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14676
HGNC: HGNC:4383
Homologene: 1563
Rbl1
Name: RB transcriptional corepressor like 1
Synonyms: retinoblastoma-like 1 (p107), p107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19650
HGNC: HGNC:9893
Homologene: 2172
Fads1
Name: fatty acid desaturase 1
Synonyms: A930006B21Rik, 0710001O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76267
VEGA: 19
HGNC: HGNC:3574
Homologene: 22753
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: MD44, MTSG1, B430305I03Rik, Atip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102103
Homologene: 100292
Usp33
Name: ubiquitin specific peptidase 33
Synonyms: Vdu1, 9830169D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 170822
Homologene: 8996
Rfx7
Name: regulatory factor X, 7
Synonyms: 2510005N23Rik, 9930116O05Rik, D130086K05Rik, Rfxdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319758
Homologene: 11275
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217351
Homologene: 23137
Gpatch8
Name: G patch domain containing 8
Synonyms: Fbm1, 5430405G24Rik, Gpatc8, ENSMUSG00000075516
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237943
Homologene: 46117
Adar
Name: adenosine deaminase, RNA-specific
Synonyms: mZaADAR, ADAR1, Adar1p150, Adar1p110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56417
HGNC: HGNC:225
Homologene: 9281
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56703
Homologene: 31761
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Itpr5, Ip3r2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: Sn, Siglec-1, CD169
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20612
Homologene: 124458
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Naip-rs6, Birc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Zfp652
Name: zinc finger protein 652
Synonyms: 9530033F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268469
Homologene: 54768
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231470
Homologene: 23516
Ada
Name: adenosine deaminase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11486
HGNC: HGNC:186
Homologene: 37249
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231646
Homologene: 82639
Trip6
Name: thyroid hormone receptor interactor 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22051
Homologene: 37757
Tdpoz1
Name: TD and POZ domain containing 1
Synonyms: Spopl1, 2cpoz56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 207213
Homologene: 128308
Npr2
Name: natriuretic peptide receptor 2
Synonyms: pwe, cn, guanylyl cyclase-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Paox
Name: polyamine oxidase (exo-N4-amino)
Synonyms: Pao, 2410012F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212503
Homologene: 72096
Bok
Name: BCL2-related ovarian killer
Synonyms: matador, mtd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 51800
HGNC: HGNC:1087
Homologene: 9632
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319719
Homologene: 131217
Cttnbp2
Name: cortactin binding protein 2
Synonyms: 4732477G22Rik, 9130022E09Rik, 3010022N24Rik, Cortbp2, ORF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30785
Homologene: 14125
Ddx28
Name: DEAD box helicase 28
Synonyms: Mddx28, DEAD (Asp-Glu-Ala-Asp) box polypeptide 28, 2410004K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71986
Homologene: 10164
Ms4a20
Name: membrane-spanning 4-domains, subfamily A, member 20
Synonyms: 1700017D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69369
Cdx2
Name: caudal type homeobox 2
Synonyms: Cdx-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12591
HGNC: HGNC:1806
Homologene: 968
Slc22a19
Name: solute carrier family 22 (organic anion transporter), member 19
Synonyms: Oat5, Slc22a9, D630043A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 207151
Homologene: 133125
Cfhr3
Name: complement factor H-related 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 624286
Homologene: 138664
Fam75d3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Iqub
Name: IQ motif and ubiquitin domain containing
Synonyms: Trs4, 4932408B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 214704
Homologene: 44790
Vmn2r60
Name: vomeronasal 2, receptor 60
Synonyms: Gprc2a-rs3, Casr-rs3, EG637898
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637898
Homologene: 129683
Myrf
Name: myelin regulatory factor
Synonyms: Gm98, LOC386531, LOC225908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Pde8b
Name: phosphodiesterase 8B
Synonyms: C030047E14Rik, B230331L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218461
HGNC: HGNC:8794
Homologene: 2758
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74682
Homologene: 10814
Dusp10
Name: dual specificity phosphatase 10
Synonyms: MKP-5, MKP5, 2610306G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 63953
HGNC: HGNC:3065
Homologene: 5215
Stk36
Name: serine/threonine kinase 36
Synonyms: Fused, 1700112N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269209
Homologene: 49432
Rnf144b
Name: ring finger protein 144B
Synonyms: E130105P19Rik, Ibrdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218215
VEGA: 13
Homologene: 27092
Nab1
Name: Ngfi-A binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17936
HGNC: HGNC:7626
Homologene: 4352
Rassf5
Name: Ras association (RalGDS/AF-6) domain family member 5
Synonyms: Rapl, Nore1B, Nore1A, 1300019G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54354
Homologene: 10296
Tlr5
Name: toll-like receptor 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 53791
Homologene: 20698
Ganc
Name: glucosidase, alpha; neutral C
Synonyms: 5830445O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76051
HGNC: HGNC:4139
Homologene: 25627
Dppa3
Name: developmental pluripotency-associated 3
Synonyms: PGC7, stella, 2410075G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73708
Homologene: 138189
Clec2i
Name: C-type lectin domain family 2, member i
Synonyms: Dcl1, OCILrP2, Clr-g, Clrg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 93675
Homologene: 136309
Ceacam1
Name: carcinoembryonic antigen-related cell adhesion molecule 1
Synonyms: Cea-1, MHVR1, Cea1, Hv-2, Cea7, Cc1, Bgp1, mmCGM2, Bgp, Cea-7, Hv2, Mhv-1, C-CAM, CD66a, mmCGM1, mCEA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26365
HGNC: HGNC:1814
Homologene: 128630
Cyp2f2
Name: cytochrome P450, family 2, subfamily f, polypeptide 2
Synonyms: Cyp2f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13107
Homologene: 73898
Tcim
Name: transcriptional and immune response regulator
Synonyms: 1810011O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69068
HGNC: HGNC:1357
Homologene: 10590
Gm906
Name: predicted gene 906
Synonyms: LOC380882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 380882
VEGA: 13
Homologene: 134512
Tmem117
Name: transmembrane protein 117
Synonyms: B930062P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320709
VEGA: 15
Homologene: 12992
Fbxl15
Name: F-box and leucine-rich repeat protein 15
Synonyms: Fbxo37, 0710008C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68431
VEGA: 19
Homologene: 44220
Ripply1
Name: ripply transcriptional repressor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 622473
Homologene: 134609
Pak3
Name: p21 (RAC1) activated kinase 3
Synonyms: PAK-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 18481
HGNC: HGNC:8592
Homologene: 55664
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 52,490,015 bp
  • A to T, chromosome 1 at 58,000,094 bp
  • C to A, chromosome 1 at 74,611,172 bp
  • G to T, chromosome 1 at 93,694,213 bp
  • G to A, chromosome 1 at 128,262,904 bp
  • T to C, chromosome 1 at 131,212,261 bp
  • A to T, chromosome 1 at 139,593,945 bp
  • C to T, chromosome 1 at 182,973,710 bp
  • C to A, chromosome 1 at 184,069,076 bp
  • T to A, chromosome 2 at 50,190,678 bp
  • A to G, chromosome 2 at 91,579,513 bp
  • T to A, chromosome 2 at 120,436,694 bp
  • A to T, chromosome 2 at 131,079,359 bp
  • C to A, chromosome 2 at 157,147,545 bp
  • G to T, chromosome 2 at 163,732,964 bp
  • T to A, chromosome 3 at 89,735,582 bp
  • T to A, chromosome 3 at 93,671,475 bp
  • T to C, chromosome 3 at 152,376,235 bp
  • C to T, chromosome 4 at 19,638,763 bp
  • A to T, chromosome 4 at 43,019,814 bp
  • A to T, chromosome 4 at 43,640,597 bp
  • T to A, chromosome 4 at 113,535,731 bp
  • G to T, chromosome 5 at 96,636,803 bp
  • A to G, chromosome 5 at 114,360,510 bp
  • G to T, chromosome 5 at 129,162,650 bp
  • A to G, chromosome 5 at 137,313,681 bp
  • C to A, chromosome 5 at 147,306,473 bp
  • T to C, chromosome 6 at 18,408,691 bp
  • T to A, chromosome 6 at 24,479,263 bp
  • T to C, chromosome 6 at 92,243,668 bp
  • T to A, chromosome 6 at 122,628,533 bp
  • T to C, chromosome 6 at 128,895,423 bp
  • A to T, chromosome 6 at 135,079,415 bp
  • C to G, chromosome 6 at 146,375,889 bp
  • A to G, chromosome 7 at 25,472,017 bp
  • C to A, chromosome 7 at 27,132,537 bp
  • A to T, chromosome 7 at 42,135,831 bp
  • T to C, chromosome 7 at 110,464,576 bp
  • T to A, chromosome 7 at 140,129,282 bp
  • T to A, chromosome 8 at 24,438,628 bp
  • T to C, chromosome 8 at 41,002,474 bp
  • T to C, chromosome 8 at 54,670,392 bp
  • T to A, chromosome 8 at 61,072,273 bp
  • A to G, chromosome 8 at 106,010,053 bp
  • T to C, chromosome 9 at 32,322,973 bp
  • T to C, chromosome 9 at 72,618,204 bp
  • A to G, chromosome 9 at 99,044,743 bp
  • T to A, chromosome 10 at 74,626,844 bp
  • T to C, chromosome 10 at 81,512,504 bp
  • T to G, chromosome 10 at 82,654,730 bp
  • T to C, chromosome 11 at 55,498,626 bp
  • C to T, chromosome 11 at 73,069,821 bp
  • T to A, chromosome 11 at 78,216,338 bp
  • T to C, chromosome 11 at 79,556,789 bp
  • T to C, chromosome 11 at 95,763,649 bp
  • T to C, chromosome 11 at 102,480,886 bp
  • C to T, chromosome 11 at 117,760,549 bp
  • G to T, chromosome 12 at 9,027,472 bp
  • T to A, chromosome 13 at 47,242,887 bp
  • A to G, chromosome 13 at 50,248,275 bp
  • C to T, chromosome 13 at 54,537,100 bp
  • A to G, chromosome 13 at 59,701,759 bp
  • G to A, chromosome 13 at 95,104,698 bp
  • A to C, chromosome 13 at 100,161,782 bp
  • T to C, chromosome 14 at 45,372,451 bp
  • T to A, chromosome 14 at 50,847,684 bp
  • A to G, chromosome 15 at 78,966,986 bp
  • T to A, chromosome 15 at 94,714,919 bp
  • C to T, chromosome 17 at 56,606,025 bp
  • G to A, chromosome 17 at 86,120,002 bp
  • A to G, chromosome 18 at 45,560,359 bp
  • T to C, chromosome 18 at 77,779,922 bp
  • A to T, chromosome 19 at 7,682,913 bp
  • C to T, chromosome 19 at 10,183,065 bp
  • G to C, chromosome 19 at 10,218,162 bp
  • A to G, chromosome 19 at 11,112,437 bp
  • A to T, chromosome 19 at 46,328,512 bp
  • TTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCT to TTCCTCCTCCTCCTCCTCCTCCTCCTCCT, chromosome X at 139,779,850 bp
  • TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC to TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC,TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC, chromosome X at 143,743,893 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0464 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038664-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.