Strain Name:
C57BL/6J-MtgxR0528Btlr/Mmmh
Stock Number:
038720-MU
Citation ID:
RRID:MMRRC_038720-MU
Other Names:
R0528 (G1), C57BL/6J-MtgxR0528Btlr
Major Collection:

Gene Information

Tnrc6b
Name: trinucleotide repeat containing 6b
Synonyms: A730065C02Rik, D230019K20Rik, 2700090M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 213988
VEGA: 15
Homologene: 66194
Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: roquin, 5730557L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381305
Homologene: 19036
Prss12
Name: protease, serine 12 neurotrypsin (motopsin)
Synonyms: Bssp-3, motopsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19142
HGNC: HGNC:9477
Homologene: 7490
Klf9
Name: Kruppel-like factor 9
Synonyms: BTEB-1, Bteb1, Klf9, 2310051E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16601
VEGA: 19
HGNC: HGNC:1123
Homologene: 931
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Zranb2
Name: zinc finger, RAN-binding domain containing 2
Synonyms: Znf265, Zis, Zfp265
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53861
Dhx38
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 38
Synonyms: Prp16, Ddx38, 5730550P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64340
Homologene: 8512
Racgap1
Name: Rac GTPase-activating protein 1
Synonyms: MgcRacGAP, GTPase, Band25, gtl11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 26934
HGNC: HGNC:9804
Homologene: 8077
Eif3l
Name: eukaryotic translation initiation factor 3, subunit L
Synonyms: PAF67, 0610011H21Rik, HSP-66Y, Eif3s6ip, Eif3eip, D15N1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223691
VEGA: 15
Homologene: 9380
Tnfrsf21
Name: tumor necrosis factor receptor superfamily, member 21
Synonyms: DR6, Death receptor 6, TR7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 94185
VEGA: 17
Homologene: 8696
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, 8030453L17Rik, E430018P19Rik, KMT2H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192195
Homologene: 10225
Islr2
Name: immunoglobulin superfamily containing leucine-rich repeat 2
Synonyms: B930052A04Rik, mbu-3, Linx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320563
VEGA: 9
Homologene: 10833
Iqsec3
Name: IQ motif and Sec7 domain 3
Synonyms: BRAG3, synarfGEF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243621
Homologene: 46091
Naca
Name: nascent polypeptide-associated complex alpha polypeptide
Synonyms: skNAC, LOC380777
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17938
VEGA: 10
HGNC: HGNC:7629
Homologene: 136025
Zfp846
Name: zinc finger protein 846
Synonyms: 2210010B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244721
Homologene: 87243
Sbf1
Name: SET binding factor 1
Synonyms: Mtmr5, B230113C15Rik, 2610510A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 77980
Homologene: 84710
Hdc
Name: histidine decarboxylase
Synonyms: Hdc-s, Hdc-e, Hdc-c, Hdc-a, L-histidine decarboxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15186
HGNC: HGNC:4855
Homologene: 20490
Atraid
Name: all-trans retinoic acid induced differentiation factor
Synonyms: HSPC013, p18, 0610007C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381629
Homologene: 15412
Lnpep
Name: leucyl/cystinyl aminopeptidase
Synonyms: gp160, vp165, IRAP, 4732490P18Rik, 2010309L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240028
VEGA: 17
HGNC: HGNC:6656
Homologene: 21148
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: D2Ertd794e, 5830435C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Dna2
Name: DNA replication helicase/nuclease 2
Synonyms: E130315B21Rik, Dna2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327762
HGNC: HGNC:2939
Homologene: 6124
Clec4f
Name: C-type lectin domain family 4, member f
Synonyms: kupffer cell receptor, D18063, Clecsf13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 51811
Homologene: 9630
Soga1
Name: suppressor of glucose, autophagy associated 1
Synonyms: D430036N24Rik, 9830001H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320706
Homologene: 52382
Cep164
Name: centrosomal protein 164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214552
Homologene: 51110
Uckl1
Name: uridine-cytidine kinase 1-like 1
Synonyms: 1110007H10Rik, Urkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68556
Homologene: 101414
Aoc1l3
Name: amine oxidase copper containing 1-like 3
Synonyms: SVS I, Svs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243377
Homologene: 18250
Astn2
Name: astrotactin 2
Synonyms: 1d8, Astnl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56079
Homologene: 77850
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238455
Homologene: 18813
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: oxygen-regulated protein 1, Orp1, mG145, Dcdc3, Rp1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19888
Homologene: 4564
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: MyHC-IId/x, Myhs-f2, Myhs-f, Myhsf2, A530084A17Rik, MYHC-IIX, myosin heavy chain 2X, IId, IId/x
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Dynap
Name: dynactin associated protein
Synonyms: 2310002L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75577
VEGA: 18
Homologene: 82463
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Lipe
Name: lipase, hormone sensitive
Synonyms: HSL, 4933403G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16890
HGNC: HGNC:6621
Homologene: 3912
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71310
Homologene: 57079
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241263
Homologene: 19381
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75718
Homologene: 19431
Megf6
Name: multiple EGF-like-domains 6
Synonyms: 2600001P17Rik, Egfl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230971
HGNC: HGNC:3232
Homologene: 45412
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-a, Slp2, Slp2-d, Slp2-c, Slp2-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83671
Homologene: 131343
Wrap73
Name: WD repeat containing, antisense to Trp73
Synonyms: DD57, 2610044M17Rik, 5330425N03Rik, Wdr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 59002
Homologene: 9857
Lrrc15
Name: leucine rich repeat containing 15
Synonyms: 5430427N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74488
Homologene: 26080
Gcc2
Name: GRIP and coiled-coil domain containing 2
Synonyms: 0610043A03Rik, 2210420P05Rik, 2600014C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70297
Homologene: 45639
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268739
Homologene: 19560
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Tmprss11b
Name: transmembrane protease, serine 11B
Synonyms: 9930019B18Rik, Tmprss11bnl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319875
Homologene: 64599
Ano7
Name: anoctamin 7
Synonyms: IPCA-5, NGEP, NGEP-L, Pcanap5, Tmem16g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 404545
Homologene: 45787
Wdr61
Name: WD repeat domain 61
Synonyms: 2810418I05Rik, 2700038L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66317
Homologene: 5884
Foxi3
Name: forkhead box I3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232077
Homologene: 52949
Hcfc2
Name: host cell factor C2
Synonyms: 1700129L13Rik, fkls
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67933
Homologene: 8337
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: PAD type IV, Pdi4, Pad4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18602
Homologene: 7883
Rbm12b1
Name: RNA binding motif protein 12 B1
Synonyms: 3000004N20Rik, Rbm12b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72397
Homologene: 28658
Olfr441
Name: olfactory receptor 441
Synonyms: GA_x6K02T2P3E9-4442577-4441645, MOR261-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258649
Homologene: 88438
Cpne4
Name: copine IV
Synonyms: 3632411M23Rik, 4933406O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74020
HGNC: HGNC:2317
Homologene: 26078
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 675969
Homologene: 104330
Rsph3a
Name: radial spoke 3A homolog (Chlamydomonas)
Synonyms: 4930524H12Rik, 1700012G05Rik, Rshl2, Rshl2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66832
VEGA: 17
Homologene: 12043
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Tpra1
Name: transmembrane protein, adipocyte asscociated 1
Synonyms: Tpra40, 40kDa, Gpr175
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 24100
Homologene: 40799
Zfp764
Name: zinc finger protein 764
Synonyms: 8030466O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233893
Homologene: 62158
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: 0610010I15Rik, mPRg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74090
Homologene: 9788
4930579C12Rik
Name: RIKEN cDNA 4930579C12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319213
Olfr1366
Name: olfactory receptor 1366
Synonyms: GA_x6K02T2QHY8-11707053-11707994, MOR130-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 258280
Homologene: 105872
Vmn1r199
Name: vomeronasal 1 receptor 199
Synonyms: V1rh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171247
Homologene: 110880
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 4,344,865 bp
  • A to G, chromosome 1 at 93,395,502 bp
  • A to T, chromosome 1 at 153,124,094 bp
  • A to T, chromosome 1 at 160,967,658 bp
  • A to G, chromosome 2 at 21,825,208 bp
  • T to C, chromosome 2 at 59,936,739 bp
  • C to T, chromosome 2 at 126,616,232 bp
  • A to G, chromosome 2 at 157,020,692 bp
  • G to C, chromosome 2 at 181,570,490 bp
  • A to G, chromosome 3 at 88,982,277 bp
  • G to A, chromosome 3 at 123,482,796 bp
  • T to C, chromosome 3 at 157,534,459 bp
  • A to G, chromosome 4 at 12,145,657 bp
  • A to G, chromosome 4 at 65,644,882 bp
  • A to T, chromosome 4 at 138,594,351 bp
  • A to G, chromosome 4 at 140,769,429 bp
  • A to G, chromosome 4 at 154,145,319 bp
  • A to G, chromosome 4 at 154,259,173 bp
  • T to A, chromosome 5 at 31,052,452 bp
  • G to T, chromosome 5 at 86,671,894 bp
  • A to T, chromosome 6 at 43,116,216 bp
  • T to A, chromosome 6 at 48,988,031 bp
  • T to A, chromosome 6 at 70,957,138 bp
  • G to A, chromosome 6 at 83,652,794 bp
  • T to C, chromosome 6 at 88,910,390 bp
  • G to C, chromosome 6 at 121,412,784 bp
  • G to A, chromosome 6 at 142,692,880 bp
  • G to A, chromosome 7 at 25,398,476 bp
  • A to G, chromosome 7 at 86,230,298 bp
  • T to C, chromosome 7 at 90,403,020 bp
  • T to A, chromosome 7 at 127,404,879 bp
  • A to G, chromosome 8 at 41,315,930 bp
  • T to C, chromosome 8 at 83,210,456 bp
  • G to T, chromosome 8 at 109,562,661 bp
  • G to A, chromosome 9 at 20,587,928 bp
  • T to A, chromosome 9 at 45,776,936 bp
  • T to A, chromosome 9 at 54,722,935 bp
  • T to A, chromosome 9 at 58,199,362 bp
  • G to A, chromosome 9 at 61,956,245 bp
  • G to A, chromosome 9 at 89,162,945 bp
  • A to T, chromosome 9 at 104,686,441 bp
  • T to A, chromosome 10 at 58,298,689 bp
  • C to A, chromosome 10 at 62,958,131 bp
  • T to G, chromosome 10 at 80,003,014 bp
  • C to A, chromosome 10 at 82,739,245 bp
  • C to T, chromosome 10 at 128,043,293 bp
  • A to G, chromosome 11 at 67,220,619 bp
  • A to T, chromosome 12 at 119,447,045 bp
  • A to G, chromosome 13 at 21,537,246 bp
  • A to T, chromosome 13 at 22,382,566 bp
  • A to G, chromosome 14 at 51,997,862 bp
  • T to C, chromosome 15 at 79,089,609 bp
  • T to C, chromosome 15 at 80,879,403 bp
  • C to T, chromosome 15 at 89,288,712 bp
  • A to T, chromosome 15 at 99,628,706 bp
  • A to G, chromosome 16 at 30,273,748 bp
  • A to T, chromosome 17 at 3,511,071 bp
  • A to G, chromosome 17 at 7,946,087 bp
  • A to G, chromosome 17 at 17,531,132 bp
  • T to A, chromosome 17 at 43,037,614 bp
  • A to G, chromosome 18 at 70,242,094 bp
  • T to C, chromosome 19 at 23,142,134 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0528 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038720-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.