Strain Name:
C57BL/6J-MtgxR0602Btlr/Mmmh
Stock Number:
038791-MU
Citation ID:
RRID:MMRRC_038791-MU
Other Names:
R0602 (G1), C57BL/6J-MtgxR0602Btlr
Major Collection:

Gene Information

Ccr2
Name: chemokine (C-C motif) receptor 2
Synonyms: CCR2B, Cmkbr2, CKR2, CCR2A, CKR2A, CKR2B, CC-CKR-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12772
HGNC: HGNC:1603
Homologene: 537
Sgca
Name: sarcoglycan, alpha (dystrophin-associated glycoprotein)
Synonyms: adhalin, Asg, 50DAG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20391
Homologene: 9
Ppp4c
Name: protein phosphatase 4, catalytic subunit
Synonyms: 1110002D08Rik, PPX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56420
HGNC: HGNC:9319
Homologene: 2038
Vps54
Name: VPS54 GARP complex subunit
Synonyms: wr, 5330404P15Rik, mSLP8, Vps54l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245944
Homologene: 5605
Arih1
Name: ariadne RBR E3 ubiquitin protein ligase 1
Synonyms: UIP77
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23806
HGNC: HGNC:689
Homologene: 111871
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: Smc4l1, 2500002A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70099
Homologene: 4015
Tcof1
Name: treacle ribosome biogenesis factor 1
Synonyms: treacle
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 21453
Homologene: 68049
Cap1
Name: CAP, adenylate cyclase-associated protein 1 (yeast)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12331
Homologene: 74572
Panx1
Name: pannexin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 55991
HGNC: HGNC:8599
Homologene: 49416
Ptprc
Name: protein tyrosine phosphatase, receptor type, C
Synonyms: CD45, Ly-5, T200, Lyt-4, B220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, 2310042E16Rik, C330002D13Rik, Coh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Ola1
Name: Obg-like ATPase 1
Synonyms: Gtpbp9, 2810405J23Rik, 2810409H07Rik, 2510025G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67059
Homologene: 5361
Bcl9
Name: B cell CLL/lymphoma 9
Synonyms: 8030475K17Rik, A330041G23Rik, 2610202E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77578
HGNC: HGNC:1008
Homologene: 3191
Ttc13
Name: tetratricopeptide repeat domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234875
Homologene: 11569
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: 6820443O06Rik, Nesp2g, nesprin-2, syne-2, Cpfl8, diminished cone electroretinogram, dice, D12Ertd777e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Sult3a2
Name: sulfotransferase family 3A, member 2
Synonyms: Gm4794
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215895
VEGA: 10
Homologene: 111031
Hephl1
Name: hephaestin-like 1
Synonyms: zyklopen, Zp, cw, LOC244698, thd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244698
Homologene: 9112
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70417
Homologene: 23771
9430038I01Rik
Name: RIKEN cDNA 9430038I01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77252
Homologene: 130777
Gm8251
Name: predicted gene 8251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Rpgrip1
Name: retinitis pigmentosa GTPase regulator interacting protein 1
Synonyms: 4930505G06Rik, A930002K18Rik, 4930401L23Rik, nmf247
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 77945
Homologene: 10679
Ptgfr
Name: prostaglandin F receptor
Synonyms: FP, PGF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19220
HGNC: HGNC:9600
Homologene: 741
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 1300010F03Rik, 4932416F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20460
Homologene: 2283
Cspg4
Name: chondroitin sulfate proteoglycan 4
Synonyms: 4732461B14Rik, NG2, AN2, Cspg4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 121021
VEGA: 9
HGNC: HGNC:2466
Homologene: 20445
Sobp
Name: sine oculis binding protein
Synonyms: Jxc1, 5330439J01Rik, 2900009C16Rik, jc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109205
Homologene: 41216
Pomgnt2
Name: protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
Synonyms: Gtdc2, C85492
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215494
VEGA: 9
Homologene: 32795
Prpf40b
Name: pre-mRNA processing factor 40B
Synonyms: 2610317D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54614
Homologene: 81828
Lrtm1
Name: leucine-rich repeats and transmembrane domains 1
Synonyms: A930016D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319476
VEGA: 14
Homologene: 49635
Pappa2
Name: pappalysin 2
Synonyms: PAPP-A2, pregnancy-associated plasma preproprotein-A2, placenta-specific 3, Pappe, PLAC3, pregnancy-associated plasma protein-E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23850
Homologene: 10661
Gal3st2c
Name: galactose-3-O-sulfotransferase 2C
Synonyms: Gm6086
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 619597
Homologene: 41471
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Prl8a8
Name: prolactin family 8, subfamily a, member 81
Synonyms: Prlpc3, PLP-Cgamma, 1600032B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74188
Homologene: 137338
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Glp1r
Name: glucagon-like peptide 1 receptor
Synonyms: GLP-1R, GLP1Rc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14652
VEGA: 17
HGNC: HGNC:4324
Homologene: 1558
Olfr1505
Name: olfactory receptor 1505
Synonyms: MOR211-4P, GA_x6K02T2RE5P-4250267-4251217, MOR211-10_i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258151
Homologene: 17394
Olfr593
Name: olfactory receptor 593
Synonyms: MOR24-2, GA_x6K02T2PBJ9-5927412-5928362
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258378
Homologene: 27147
A530032D15Rik
Name: RIKEN cDNA A530032D15Rik gene
Synonyms: LOC381287
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381287
Homologene: 131208
Parp6
Name: poly (ADP-ribose) polymerase family, member 6
Synonyms: 1700119G14Rik, 3110038K10Rik, 2310028P13Rik, C030013N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67287
VEGA: 9
Homologene: 10627
Olfr1497
Name: olfactory receptor 1497
Synonyms: GA_x6K02T2RE5P-4127765-4126821, MOR212-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258736
Homologene: 17373
Cd226
Name: CD226 antigen
Synonyms: DNAM-1, Pta1, DNAM1, TLiSA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225825
Homologene: 4787
Slc9b1
Name: solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
Synonyms: 4933425K02Rik, 1700094G20Rik, 4933424B12Rik, Nhedc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74446
Homologene: 49914
Nrm
Name: nurim (nuclear envelope membrane protein)
Synonyms: 2610307M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106582
HGNC: HGNC:8003
Homologene: 38294
Smco1
Name: single-pass membrane protein with coiled-coil domains 1
Synonyms: 2310010M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 69576
Homologene: 18842
Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Synonyms: HER-2, ErbB-2, l11Jus8, HER2, c-erbB2, Neu oncogene, c-neu, Neu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13866
HGNC: HGNC:3430
Homologene: 3273
Tcam1
Name: testicular cell adhesion molecule 1
Synonyms: 4930570F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75870
Homologene: 123944
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 626596
Homologene: 75047
Lgi2
Name: leucine-rich repeat LGI family, member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246316
Homologene: 10048
Vmn1r171
Name: vomeronasal 1 receptor 171
Synonyms: V1rd7, V3R7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 81012
Homologene: 128341
Col25a1
Name: collagen, type XXV, alpha 1
Synonyms: 2700062B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77018
Homologene: 57111
Cd1d2
Name: CD1d2 antigen
Synonyms: Cd1b, CD1.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12480
HGNC: HGNC:1637
H2ac18
Name: H2A clustered histone 18
Synonyms: Hist2, Hist2h2aa1, H2a-615
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15267
Homologene: 116071
Sgms2
Name: sphingomyelin synthase 2
Synonyms: 5133401H06Rik, 4933405A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74442
Homologene: 32705
Nrbf2
Name: nuclear receptor binding factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 641340
Homologene: 41473
Gtf2h2
Name: general transcription factor II H, polypeptide 2
Synonyms: 44kDa, Btf2p44, p44, basal transcription factor 2, p44 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 23894
Homologene: 1159
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 44,059,967 bp
  • A to G, chromosome 1 at 46,324,842 bp
  • C to G, chromosome 1 at 85,099,505 bp
  • A to G, chromosome 1 at 94,009,179 bp
  • C to T, chromosome 1 at 138,089,485 bp
  • A to G, chromosome 1 at 158,763,055 bp
  • A to G, chromosome 2 at 73,093,712 bp
  • G to C, chromosome 3 at 69,009,538 bp
  • T to C, chromosome 3 at 86,987,803 bp
  • T to C, chromosome 3 at 96,245,550 bp
  • T to C, chromosome 3 at 97,205,786 bp
  • A to G, chromosome 3 at 130,575,414 bp
  • T to A, chromosome 3 at 131,325,107 bp
  • C to A, chromosome 3 at 135,397,755 bp
  • G to A, chromosome 3 at 151,835,202 bp
  • T to A, chromosome 4 at 115,024,423 bp
  • T to C, chromosome 4 at 122,872,409 bp
  • T to C, chromosome 5 at 52,554,423 bp
  • G to T, chromosome 7 at 23,633,177 bp
  • A to C, chromosome 7 at 103,212,580 bp
  • A to G, chromosome 7 at 126,789,082 bp
  • T to C, chromosome 7 at 137,376,361 bp
  • A to T, chromosome 8 at 124,674,366 bp
  • A to G, chromosome 9 at 15,010,204 bp
  • T to A, chromosome 9 at 15,089,051 bp
  • T to C, chromosome 9 at 56,888,017 bp
  • A to G, chromosome 9 at 59,394,871 bp
  • A to G, chromosome 9 at 59,649,365 bp
  • A to G, chromosome 9 at 75,266,196 bp
  • A to G, chromosome 9 at 121,982,273 bp
  • A to G, chromosome 9 at 124,106,621 bp
  • A to T, chromosome 10 at 33,782,048 bp
  • T to A, chromosome 10 at 43,022,389 bp
  • G to A, chromosome 10 at 67,267,826 bp
  • A to G, chromosome 11 at 21,306,434 bp
  • A to T, chromosome 11 at 94,963,235 bp
  • G to A, chromosome 11 at 98,434,271 bp
  • G to A, chromosome 11 at 106,284,078 bp
  • AGAGTGAG to AGAGTGAGTGAG, chromosome 12 at 76,097,960 bp
  • T to A, chromosome 13 at 27,508,550 bp
  • A to G, chromosome 13 at 100,469,025 bp
  • T to C, chromosome 14 at 29,022,222 bp
  • A to G, chromosome 14 at 52,133,856 bp
  • T to G, chromosome 14 at 79,020,620 bp
  • T to C, chromosome 15 at 35,422,368 bp
  • T to C, chromosome 15 at 36,139,872 bp
  • A to C, chromosome 15 at 58,577,945 bp
  • C to A, chromosome 15 at 99,304,471 bp
  • A to G, chromosome 16 at 32,273,244 bp
  • T to C, chromosome 17 at 30,909,227 bp
  • C to A, chromosome 17 at 35,864,264 bp
  • T to G, chromosome 18 at 57,262,100 bp
  • C to A, chromosome 18 at 60,833,533 bp
  • C to T, chromosome 18 at 89,269,011 bp
  • T to C, chromosome 19 at 13,794,662 bp
  • A to G, chromosome 19 at 13,919,781 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0602 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038791-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.